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4841
Genetic parameters and parental and early-life effects of boar semen traits
Published 2025-02-01“…Early-life effects included the dam’s parity, ages of the dam and sire, gestation length, litter size, litter sex ratio, number of piglets born alive, number of litter mates at weaning, rearing length, and weight gain. …”
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4842
Evaluation of the Clinical Efficacy of Prednisolone in the Treatment of Inflammatory Bowel Diseases with Different Dosage Methods
Published 2023-05-01“…In this study were included 86 patients aged from 18 to 65 years with moderate or severe active inflammatory bowel disease (61 — UC, 25 — CD). …”
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4843
The relationship between negative psychological state and quality of life among cardiovascular disease patients in China: the masking effect of abnormal dietary behavior
Published 2025-02-01“…The purpose of this study was to construct a moderated mediation model to explore the roles of abnormal dietary behavior and family health in the mechanism through which depression/anxiety influences Quality of life (QoL) in patients with cardiovascular disease.MethodsA field survey was conducted in China and ultimately included 730 patients with cardiovascular disease aged 20–60 years. Data were collected using the Europe Quality of five-dimensional five-level questionnaire, Short-Form of the Eating Behavior Scale, Patient Health Questionnaire-9, Generalized Anxiety Disorder-7, and the Chinese version of the short-form of the Family Health Scale. …”
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4844
Using Dose-Effect Relationship for Optimising Systemic Corticosteroid Dosage in Treatment of Inflammatory Bowel Diseases
Published 2020-12-01“…The study included 86 patients with moderate to severe active disease (61 with UC and 25 with CD) aged 18 to 65 years. To induce remission, all patients had the first course of prednisone at a starting dose of 30 to 60 mg/day, with a subsequent reduction. …”
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4845
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4846
Assessing awareness and treatment knowledge of preventable blindness in rural and urban South African communities
Published 2024-06-01“…Both groups were aware of the role of ageing in blindness. Conclusion. Urban participants in this study appeared to be more knowledgeable than rural participants about the causes and symptoms of blindness and its treatment options. …”
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4847
Shift from chronic to episodic migraine frequency in a long-term phase 3 study of galcanezumab
Published 2025-02-01“…Ability to convert patients from chronic migraine frequency to episodic migraine (EM) frequency is a clinically relevant and desirable outcome when prescribing preventive treatments to patients with CM. Methods Patients aged 18–65 years with an ICHD-3β diagnosis of CM were randomized 2:1:1 to receive monthly injections of placebo (N = 558), galcanezumab 120 mg with a 240-mg loading dose (N = 278), or galcanezumab 240 mg (N = 277) during a 3-month double-blind period of the phase 3 REGAIN trial. …”
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4848
Cost-effectiveness analysis for implementation of smoking cessation strategies at primary health care settings in Tamil Nadu.
Published 2025-01-01“…<h4>Objectives</h4>To compare the cost-effectiveness of the smoking cessation of proposed strategies (PSs), PS1: enhanced counselling (EC) + nicotine replacement therapy (NRT) + bupropion tablet; PS2: behavioural intervention (BI) + NRT + promotion of bupropion sustained release (SR); PS3: EC + NRT + promotion of bupropion SR with the current strategy (BI +NRT+ Bupropion) in a population of smokers aged ≥15 years attending the PHC in Tamil Nadu.<h4>Methods</h4>In this hypothetical cohort of 100,000 individuals using the decision tree analysis, a cost-effectiveness assessment was conducted for both proposed and existing strategies. …”
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4849
A decomposition analysis of sociodemographic factors and non-cigarette tobacco use as contributors to the change in smoking rates in South Africa between 2017/18 and 2021
Published 2024-06-01“…However, the use of waterpipe/hubbly, ECigs, RYO cigarettes and snuff increased significantly. Women, individuals aged <35 years and black Africans had the largest increase in waterpipe/hubbly and ECig use. …”
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4850
Using a co-design approach to develop a Preventative Online Mental Health Program for Youth (POMHPY): a quality improvement project
Published 2025-02-01“…The current paper details the co-design approach to creating a Preventative Online Mental Health Program for Youth (POMHPY)—a virtually delivered program designed for Ontario youth ages 12 to 25 that promotes mental, physical, and social wellbeing. …”
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4851
The Effects of Digital eHealth Versus Onsite 2-Day Group-Based Education in 255 Patients With Irritable Bowel Syndrome: Cohort Study
Published 2025-02-01“…MethodsPatients diagnosed with IBS, aged 15-70 years, were enrolled after referral to the Section of Gastroenterology at Haukeland University Hospital, Norway. …”
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4852
Who is to blame for the ‘problem’ of teenage pregnancy? Narratives of blame in two South African communities
Published 2025-02-01“…Data derived from seventy-one in-depth interviews conducted with forty AGYW aged between 15 and 24, twenty-four parents/caregivers of AGYW, five service providers, ten school educators, and two other community members. …”
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4853
Clinical Burden and Healthcare Resource Use of Asthma in Children in the UK
Published 2025-02-01“…We assessed the clinical and economic burden of asthma in children in the UK to better understand the impact of pediatric asthma.Methods: This was a retrospective, case-matched, longitudinal analysis using the Clinical Practice Research Datalink GOLD database and linked patient-level data (Hospital Episode Statistics and Office for National Statistics datasets) of selected patient (aged 6– 11 years) records in 2017. Severe exacerbation and re-exacerbation rates per patient-year (PPY), all-cause healthcare resource utilization (HCRU), and HCRU-related costs were assessed in asthma patients versus matched non-asthma controls, stratified by severity.Results: Among 5950 patients, severe exacerbation rate was 0.06, 0.17 and 0.31 PPY for mild, moderate, and severe asthma, respectively. …”
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4854
HIV viral load suppression rates among adults and children living with HIV in the North West Region of Cameroon: A call for action!
Published 2025-01-01“…<h4>Introduction</h4>HIV continues to be a major public health problem in Cameroon where 2.7% of the population aged 15 to 49 are living with HIV. The prevalence remains higher in females, 3.4% versus 1.9% in males. …”
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4855
Clinical Profile and Prescription Patterns in Culture-proven Enteric Fever in Children
Published 2024-03-01“…Materials and methods: We carried out a retrospective study of culture-proven enteric fever in children aged 0–18 years between January 2018 and March 2023. …”
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4856
Clinical decision fatigue: a systematic and scoping review with meta-synthesis
Published 2025-02-01“…This review aimed to understand DF determinants and consequences and capture motivational factors overlooked in the existing reviews.Design Systematic and scoping review (ScR) with meta-synthesis.Eligibility criteria Empirical and non-empirical papers on clinical DF or related constructs directly impacting clinical decision-making were considered, with doctors of all ages, sexes and nationalities as participants. The Preferred Reporting Item for Systematic Reviews and Meta-analyses scoping review checklist has been applied and checked.Information sources Six databases were systematically searched by two independent researchers according to a predefined set of keywords.Results 43 papers were included, of which 25 were empirical. …”
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4857
Urinary concentrations of arsenic species in older Dutch adults and risk of chronic kidney disease
Published 2025-02-01“…To assess the risk of internal As exposure, toxic relevant arsenic (TRA) (sum of arsenite (As(III)), arsenate (As(V)), and their methylation metabolites, monomethylarsonate (MMA) and dimethylarsinate (DMA)) in urine should be used.Morning urine samples of 288 Dutch adults (aged 52–91 years) were analysed for As(III), As(V), MMA, DMA, arsenobetaine (AsB) and total As using ICP-MS. …”
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4858
Validating a digital depression prevention program for adolescents in Jordan: cultural adaptation and user testing in a randomized controlled trial
Published 2025-02-01“…It evaluated the feasibility, cultural acceptability, and effectiveness of the translated and culturally adapted DHI, named Al-Khaizuran, with comparisons to school-based group CBT.MethodsA two-arm, single-blind randomized controlled trial with a mixed-methods design was conducted among 109 Jordanian adolescents aged 15–17 years experiencing mild to moderate depression. …”
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4859
Relationship of monocyte to high-density lipoprotein ratio (MHR) and other inflammatory biomarkers with sarcopenia: a population-based study
Published 2025-02-01“…Methods The study comprised 10,321 participants aged 20 years and above from the United States. Multiple logistic regression was performed to explore the association between ln-transformed MHR, SII, NLR, NHHR and low muscle mass. …”
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4860
Combination of Mangosteen (Garcinia mangostana L.) Pericarp Extract and Physical Exercise Decreases Atherosclerotic Lesions in Atherogenic Diet-Fed Rats
Published 2024-12-01“…Twenty-five male Wistar rats (Rattus norvegicus) aged 6-8 weeks were randomly divided into five groups of five rats each: C (control, normal diet), CH (atherogenic diet), T1 (atherogenic diet plus MP extract 800 mg/kg/day in three divided doses with PE), T2 (atherogenic diet plus MP extract-loaded nanoemulsion 50 mg/kg/day with PE), and T3 (atherogenic diet plus atorvastatin 1.44 mg/day with PE). …”
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