Health Canada's use of its priority review process for new drugs: a cohort study by Joel Lexchin

“…The purpose of this study is to compare Health Canada's use of priority reviews to therapeutic ratings from two independent organisations, the Patented Medicine Prices Review Board (PMPRB) and the French drug bulletin Prescrire International, over the period 1 January 1997–31 December 2012.Design Cohort study.Data sources Annual reports of the Therapeutic Products Directorate, and the Biologics and Genetic Therapies Directorate; evaluations of therapeutic innovation from PMPRB and Prescrire International; WHO Collaborating Centre for Drug Statistics Methodology.Interventions Assessments by PMPRB and Prescrire International treated as a gold standard for postmarket therapeutic value.Primary and secondary outcome measures Drug-by-drug comparison between the review status from Health Canada and the therapeutic status from PMPRB/Prescrire using κ values, and positive and negative predictive values. …”
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Effect of The Duration of The Diagnosis on DNA Methylation Changes in Three Different Diabetic Genes in Type 2 Diabetes Mellitus by Harem Othman Smail

“…Patients with type 2 diabetes, particularly those who had just received a diagnosis, showed higher levels of methylation than the control group. …”
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Case Report: Surgical treatment of lumbar ligamentum flavum cysts combined with spinal instability causing radiculopathy by Keshi Yang, Keshi Yang, Changbin Ji, Changbin Ji, Dawei Luo, Dawei Luo, Jiwei Yin, Jiwei Yin, Xiaozhe Wu, Xiaozhe Wu, Hui Xu, Hui Xu

“…PurposeThis study aimed to describe a case of a patient with a lumbar ligamentum flavum cyst combined with spinal instability who underwent cyst resection and transforaminal lumbar interbody fusion (TLIF).MethodsWe present a rare case of a patient with a lumbar ligamentum flavum cyst combined with spinal instability causing radiculopathy. …”
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The effect of anti mullerian hormone and follicle stimulating hormone discordance on oocyte quality and live birth rates by Seray Kaya, Murat Genc, Bensu Bulut, Medine Akkan Oz, Mustafa Ozturk

“…This retrospective study was conducted on 82 patients who sought infertility treatment at Assisted Reproductive Techniques Center of Gulhane Training and Research Hospital between January 1, 2016, and December 31, 2020. …”
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Decision experiences in joint replacement surgery for patients with haemophilic arthritis: A qualitative study by YaNan Kan, YunChun Bao, Fuying Ye

“…Methods Fifteen HA patients who were candidates for joint replacement surgery at a tertiary and first-class hospital in Zhejiang Province were interviewed using a semistructured in-depth interview from January to December 2023. …”
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Vaginal Preparation with Povidone Iodine and Postcesarean Infectious Morbidity: A Retrospective Trial by Esra Turgut Yavuz, Erdal Malatyalıoğlu, Fatma Devran Bıldırcın

“…STUDY DESIGN: This study included 250 pregnant women undergoing cesarean delivery, who applied our clinic between the dates 2010-2011. …”
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FACTORS AFFECTING THE ADHERANCE OF POST CABG PATIENTSIN CARDIAC REHABILITATION-A CROSS-SECTIONALSTUDY IN KARACHI by Muniba Khanum et al

“…Adherence was observed in patients who have accepted their condition (81.1%), learned to cope with the limitations (76.8%), were comfortable with exercise regime (67.4%), believed that exercise will decrease the deconditioning (74.9%) and will improve physical fitness (20.8%). …”
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Evaluation of zonulin levels in patients with migraine by Gözde Ülfer, Burcu Polat, Ahmet Yabalak, Çağrı Çakıcı

“…Methods The sample comprised 40 individuals who had migraine and 40 controls. Disease duration, attack duration, attack frequency, Visual Analog Scale (VAS) scores, and comorbidities were available for the migraine group. …”
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Efficacy of ileostomy in Crohn's disease of the large intestine with perianal involvement by Yu. A. Shelygin, V. N. Kashnikov, K. V. Bolikhov, A. V. Vardanyan, I. L. Khalif

“…Overall 43 patients with Crohn's disease of the large intestine with perianal involvement who underwent ileostomy in January, 1998 to July, 2009 in The State scientific center of coloproctology were included in original study. …”
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Olabiyi Babalola J. Yai (1939-2020): Philosopher, Polymath, Humanist by Sanya Osha

“…Throughout the huge conference, I had been beside Irele, ravenously tapping into his wealth of knowledge and experience, plying him with an endless barrage of questions relating to our intellectual history and the key figures who had indelibly marked and shaped its trajectory. …”
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Regulation of the Employment Status of Seafarers by Boris Jerman

“…This article discusses the specifics of the employment relationship of seafarers who not only perform their obligations on a ship under an employment contract, but also live far away from their permanent residence, with limited contact with their home environment, including their families. …”
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The role of non-alcoholic fatty liver disease in the formation of atherosclerotic vascular lesions in patients with abdominal obesity by N. L. Denisov, V. B. Grinevich, Ye. V. Chernetsova, Yu. A. Kravchuk, K. V. Ivashkin

“…The study involved 60 patients with AO (waist circumference ≥80 cm in women and ≥94 cm in men) and NAFLD who provided written informed consent to participate in the study. …”
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A Comparative Study Evaluated the Performance of Two-class Classification Algorithms in Machine Learning by Shilan Abdullah Hassan, Maha Sabah Saeed

“…The Organization for World Health (WHO) reports that around 17 million individuals worldwide pass away from cardiovascular diseases (CVD), notably heart attacks and strokes, each year. …”
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The effect of circuit games on manipulative movement for elementary school students aged 9-10 years by Fika Widiana Kuspratiwi, Wawan Sundawan Suherman, Amat Komari

“…This circuit-training program is, post 1) Fabric Volleyball Game, post 2) Football Circuit Game, post 3) Suki Basketball Circuit Game, post 4) Quickie (Who’s Fast?) Game. Each post is done for 10 minutes, recovery 5-6 minutes, and this program is implemented for 16 meetings. …”
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Differencesin Variations of Qira'at al-Sab' Tariq al-Shatibiyyah in Usul al-Qira'at based on verses 1-31 in Surah al-Baqarah by M. Jismani Yusoff, Nor Hafizi Yusof, Ismail Abd Halim

“…The results of the study can help individuals who study the Ilmu Qira'at know the difference between the variations of Qira'at al-Sab' Tariq al-Shatibiyyah in Usul al-Qira'at and then be able to practice it in the verses involved in this study.…”
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Effects of dump site soil on the leaf structures of <i>Luffa cylindrical</i> (sponge gourd) and <i>Amaranthus viridis</i> (green amaranth) by S.I. Musa, K.O. Awayewaserere, K.I. Njoku

“…All the HMs detected at the three spots and control were below the World Health Organization (WHO) and Dutch pollutant standard level, except for (Zn) which was at the exact limit (50.000Mg/kg). …”
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Risk Factors and Prevention of Upper Gastrointestinal Complications Associated with Nonsteroidal Anti-Inflammatory Drugs by N. V. Bakulina, S. V. Tikhonov, K. A. Nagornova

“…The use of selective cyclooxygenase-2 inhibitors is associated with a reduced risk of gastrointestinal complications. All patients who are going to receive NSAIDs should be diagnosed with H. pylori and treated with eradication therapy if this infection is detected. …”
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Globalization, Security and Governance Challenges in Nigeria by WILSON SIMON OKWOLI, LAMI LENTON ANUGA, JOSEPH ABOGENYE ANUGA

“…It also found that the inability of the Nigerian state to deliver on material development aspirations of citizens exposes the country to global terrorist actors who highjack the difficulties of governance to pursue their own ends. …”
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Refining the Make My Day stroke prevention intervention for primary healthcare through co-creation with stakeholders by Cecilia Johnsson, Elin Jakobsson, Maria Hagströmer, Susanne Guidetti, Ann-Helen Patomella, Eric Asaba

“…Method This was an iterative co-creation process of five collaborative workshops engaging stakeholders; healthcare professionals (HP), and persons at risk for stroke, who participated in or delivered a stroke prevention intervention in primary healthcare. …”
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INVESTIGATING RISKS IN DEPENDENCE PRODUCING DRUGS USERS AMONGSUB-POPULATION OF HIGHER EDUCATION INSTITUTES IN KARACHI;.A CROSS-SECTIONAL STUDY by Shamsul Arfin Qasmi et al

“…A total of 445 participants who fulfilled the inclusion criteria were inducted in present chosen for this study. …”
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