Changes in faecal haemoglobin values over sequential rounds of faecal immunochemical tests (FIT) in a surveillance population by Amanda J Cross, Kate Wooldrage, Gemma Mortell, Gwen A Murphy

“…Participants were grouped based on changes between FIT rounds, with changes defined as absolute differences ≥4 µg/g, and positivity at round 3.Results Among 4412 participants, the largest group (n=2773) was the no change category, which had the lowest ACN detection rate (4.7%, 95% CI: 3.9 to 5.5). The serial increase group with a positive round 3 value (n=46) had the highest ACN detection rate (32.6%, 95% CI: 19.5 to 48.0).Conclusion No change in FIT result across multiple rounds was associated with a low ACN detection rate, while a serial increase was associated with higher ACN detection rates. …”
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