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661
Teachers' well-being and performance at government-aided primary schools in Rubanda District's Bubaare Sub-County
Published 2021“…This study was carried out to establish the influence of teachers’ welfare on their performance in government aided primary schools in Bubaare sub-county in Rubanda District South Western Uganda. The study used cross sectional survey research design. …”
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Transformer-based travel time estimation method for plateau and mountainous environments
Published 2025-02-01“…Two datasets were constructed based on measurements from two selected areas in eligible plateau and mountainous regions of western China. For each dataset, two categories of features were defined: terrain-weather features and spatio-temporal features. …”
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664
KLF5 promotes esophageal squamous cell carcinoma radioresistance by targeting the Keap1-Nrf2 pathway
Published 2025-02-01“…The effects of overexpression or downregulation of KLF5 on anti-irradiated cells' proliferation, migration, invasion, and apoptotic activity were studied through colony formation assay, Transwell assay, and flow cytometry. Western blot can detect the activity of Nrf2 signaling pathway in cells and tissues. …”
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665
Impact of Paracoccus sp. EGY7 carotenoids on triple-negative breast cancer cells: invitro study
Published 2025-02-01“…The extract induced apoptosis, as evidenced by significantly increased BAX/BCL-2 gene expression ratios at 600 and 1200 µg (p < 0.05). Western blotting showed increased BAX protein expression at 600 and 1200 µg compared to the control group (p < 0.001), and significantly lower BCL-2 protein expression (p = 0.000005 for 1200 µg and p = 0.0001 for 600 µg). …”
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666
Effects of coenzyme q10 supplementation on metabolic and reproductive outcomes in obese rats
Published 2025-02-01“…The cafeteria diet (CAF) serves as an animal model mirroring Western diet habit. Coenzyme Q10 (CoQ10), known for enhancing reproductive outcomes in various pathologies, is not fully understood for its effects on obesity treatment. …”
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667
Sphingosine kinase 1 promotes M2 macrophage infiltration and enhances glioma cell migration via the JAK2/STAT3 pathway
Published 2025-02-01“…Enrichment analysis and Western blotting revealed that SPHK1 functions as a JAK2/STAT3 pathway controller. …”
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668
AKT1-Mediated NOTCH1 phosphorylation promotes gastric cancer progression via targeted regulation of IRS-1 transcription
Published 2024-12-01“…Methods The study utilized databases such as PhosphositePlus, TRANSFAC, CHEA, GPS 5.0, and TCGA, along with experimental techniques including Western Blot, co-IP, in vitro kinase assay, construction of lentiviral overexpression and silencing vectors, immunoprecipitation, modified proteomics, immunofluorescence, ChIP-PCR, EdU assay, Transwell assay, and scratch assay to investigate the effects of AKT1-induced Notch1 phosphorylation on cell proliferation, invasion and migration in vitro, as well as growth and epithelial-mesenchymal transition (EMT) in vivo. …”
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669
Best practice mechanisms for biodiversity conservation law and policy
Published 2023-01-01“…The literature demonstrated that when it comes to biodiversity conservation law, the concept of ‘best practice’ is elusive, and does not necessarily equate to a reversal in species decline. Further, most western countries utilise the same legal mechanisms (also known as policy tools) for biodiversity conservation, although some countries implement these laws more effectively than others. …”
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670
DEEP STRUCTURE, TECTONIC EVOLUTION AND HYDROCARBON POTENTIAL OF THE KALAMIT SWELL (NORTHWESTERN SHELF OF THE BLACK SEA) ACCORDING TO DENSITY MODELING DATA
Published 2024-10-01“…The southern one belongs to the subcontinental type of transitional block between the SP and the Western Black Sea Basin. The boundaries of the КS are determined, which are mostly controlled by faults. …”
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671
MicroRNA-541-3p/Rac2 signaling bridges radiation-induced lung injury and repair
Published 2025-06-01“…Flow cytometry, polymerase chain reaction, and western blotting were used to analyze cell necroptosis, target gene expression, and target protein expression, respectively. …”
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672
A missense variant in the SOX5 gene (c.221C > T) is associated with intellectual disability
Published 2025-02-01“…Additionally, protein stability was evaluated using I-Mutant, and 3D protein structures were modeled with I-TASSER. Western blots and QPCR were employed to assess gene expression and protein stability. …”
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Mechanistic insights into 125I seed implantation therapy for Cholangiocarcinoma: focus on ROS-Mediated apoptosis and the role of GPX2
Published 2024-06-01“…Protein expression was determined by Western blotting and immunohistochemistry. Results Our results demonstrate that 125I seeds effectively inhibited tumor growth in the rabbit VX2 tumor model and promoted the apoptosis of CCA cells in vitro in a dose-dependent manner. …”
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CSF3 promotes colorectal cancer progression by activating p65/NF-κB signaling pathway and inducing an immunosuppressive microenvironment
Published 2025-03-01“…Methods: CSF3 expression levels in CRC cells and tissues were detected by quantitative real-time PCR (qRT-PCR), western blot and immunohistochemistry (IHC). In vitro and in vivo assays were performed to investigate the oncogenic function of CSF3 in the tumor associated malignant phenotypes and the tumorigenic capability of CRC cells. …”
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675
ASKAP Observations of the Radio Shell in the Composite Supernova Remnant G310.6-1.6
Published 2025-01-01Get full text
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676
Call for Papers: Demography Prize for Young Researches 2016/2017
Published 2016-12-01“…Published in 2015 by a France-based think tank of the same name, it analyses the situation of young people in 64 Western and non-Western countries by means of no less than 59 different social, economic and political indicators. …”
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Stress buffering effects of physical activity in adolescents: the moderating role of physical activity attitudes
Published 2025-02-01“…Methods A stratified and cluster sampling method was used to select 2420 junior high school students from nine provinces from each of the three economic zones (with high GDP level, medium GDP level, and low GPD level) of eastern, western, and central China and the Adolescent Self-Rating Life Events Checklist, the Calgary Symptoms of Stress Inventory, the Physical Activity Rating Scale, and the behavioral attitude dimension of the Physical Activity Attitude Scale were used to investigate adolescent stress events, stress symptoms, physical activity, and physical activity attitudes respectively. …”
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