The impact of land use transition on ecosystem service value in Lixiahe area: Multi-scenario simulation based on Markov-FLUS model by CHEN Xinwei, LI Hongbo, ZHANG Wenbo, GE Xiaoping

“…The main form of land use type transformation was from cultivated land to wetland or construction land, and the active transformation areas were concentrated in the central and eastern and western boundary areas. (2) The ecosystem service value of the study area in 1990, 2005 and 2020 showed a year-on-year increasing trend, and the spatial pattern was relatively stable. …”
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A high offset stem design does not increase stem migration under full weight bearing in cementless total hip arthroplasty: a model-based RSA study by Tobias Reiner, Robert Sonntag, Jan Philippe Kretzer, Michael Clarius, Eike Jakubowitz, Stefan Weiss, Stefan Kinkel, Tilman Walker, Tobias Gotterbarm, Timo Albert Nees

“…Clinical outcomes were assessed using the modified Harris Hip Score (HHS) and the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC). …”
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Staphylococcus aureus induces mitophagy via the HDAC11/IL10 pathway to sustain intracellular survival by Yaji Yang, Haotian Zhou, Feilong Li, Yanhao Zhang, Jianye Yang, Yidong Shen, Ning Hu, Quanming Zou, Leilei Qin, Hao Zeng, Wei Huang

“…Additionally, confocal microscopy, flow cytometry, Mdivi-1 intervention, and Western blot were utilized to validate the role of mitophagy in supporting S. aureus survival. …”
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Comparative effectiveness of laparoscopic versus open colectomy in colon cancer patients: a study protocol for emulating a target trial using cancer registry data by Semaw Ferede Abera, Gabriele Robers, Anika Kästner, Ulrike Stentzel, Kerstin Weitmann, Wolfgang Hoffmann

“…Methods: Using Mecklenburg-Western Pomerania Cancer Registry data from 2008 to 2018, we will emulate a phase III, multicenter, open-label, two-parallel-arm hypothetical target trial in adult patients with stage I–III colon cancer who received laparoscopic or open colectomy as an elective treatment. …”
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Effects of perioperative treatment of resectable adenocarcinoma of esophagogastric junction by immunotherapy (Adebrelimab) combined with chemotherapy (XELOX): protocol for a single... by Yingyi Li, Yuqin Cao, Xipeng Wang, Chengqiang Li, Liqin Zhao, Hecheng Li

“…Considering the differences in chemotherapy regimen tolerance between Asian and Western populations, this study intends to evaluate the suitability of Adebrelimab combined with XELOX chemotherapy for the Asian population. …”
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CircSPG21 ameliorates oxidative stress-induced senescence in nucleus pulposus-derived mesenchymal stem cells and mitigates intervertebral disc degeneration through the miR-217/SIRT... by Yongbo Zhang, Sheng Yang, Xuan You, Zhengguang Li, Liuyang chen, Rui Dai, Hua Sun, Liang Zhang

“…Interactions among circSPG21, miR-217, and the NAD-dependent protein deacetylase sirtuin-1 (SIRT1) were validated through dual-luciferase assays, RNA fluorescence in situ hybridization and RNA immune precipitation. β-Gal staining, EdU staining, Western blotting, JC-1 assays, cell cycle analysis, and quantitative reverse transcription PCR (RT‒qPCR) were used to examine the functions of these molecules in TBHP-induced senescent NPMSCs. …”
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Experiences of HIV Positive Serostatus Disclosure to Sexual Partner Among Individuals in Discordant Couples in Mbarara City, Southwestern Uganda. by Atwijukiire, Humphrey, Nakidd, Gladys, Tweheyo, Otwine Anne, Kabami, Jane

“…The current study addressed this research gap and explored the lived experiences of serostatus disclosure among discordant couples in Mbarara City, South Western Uganda. Participants and Methods: We conducted 12 in-depth interviews with the help of a translated interview guide, and they were audio recorded. …”
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Basic Molecular Biology, Metabolic and Immunological Mechanisms of Fecal Microbiota Transplantation by O. V. Goloshchapov, A. V. Beynarovich, A. B. Chukhlovin, R. V. Klementeva, A. A. Shcherbakov, E. A. Bakin, I. K. Golubovskaya, N. D. Ventslovayte, O. S. Yudintseva, M. V. Gorchakova, V. E. Karev, M. A. Kucher, M. A. Suvorova, E. V. Svetkina, G. G. Rodionov, V. V. Gostev, S. V. Sidorenko, I. S. Moiseev, A. D. Kulagin

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The study of miRNA-211 affects melanogenesis progress in Cashmere goats via suppressing <i>AP1S2</i> by B. Zhang, R. Liu, T. Ma, X. Li, Y. Zhao, H. Su, J. Li, Y. Li, H. Jiang, Q. Zhang

“…In B16-F10 cells, which overexpress miRNA-211 and goat skin, the opposite expression trends between <i>AP1S2</i> and miRNA-211 were analyzed by reverse transcription–quantitative PCR (RT-qPCR) and western blot. And their opposite expression trends were confirmed in B16-F10 cells by immunofluorescence. …”
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Functional analysis of heterozygous variants in the SALL1 gene in 2 children with Townes-Brocks syndrome with FSGS by Rong Liang, Bixia Zheng, Chunli Wang, Sanlong Zhao, Wei Zhou, Ying Chen, Ruochen Che

“…The Sall1 protein expression level was detected by western blotting. Immunofluorescence was also employed to detect the subcellular localization of SALL1. …”
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Impact of COVID-19 Control Measures on Trace Gases (NO2, HCHO and SO2) and Aerosols over India during Pre-monsoon of 2020 by Mriganka Sekhar Biswas, D. C. Ayantika

“…A significant seasonal reduction in SO2 was noted over western India (WI) and SI. Additionally, widespread decline covering all the zones was found in the pre-monsoon AOD. …”
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Protocol for a randomised phase 3 trial evaluating the role of Finasteride in Active Surveillance for men with low and intermediate-risk prostate cancer: the FINESSE Study by Samuel Smith, Peter Sasieni, William Cross, Richard Bryant, Steven Kennish, James Catto, Rachel Hubbard, Simon Faulkner, Rohit Chahal, Mohantha Dooldeniya, Marcus Cumberbatch, Bernard North, Alastair D Lamb, Roseann Kealy, Selina Bhattrai

“…Background Prostate cancer (PCa) is the most common male malignancy in the western world. Many men (40%) are diagnosed with localised low or intermediate-risk PCa, which is suitable for active surveillance (AS). …”
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Jianpi Yiqi Busui prescription alleviates myasthenia gravis by regulating Th17 through the TAK1/P38 MAPK/eIF-4E signaling pathway by Zhuming Chen, Jing Lu, Tianying Chang, Dongmei Zhang, Yibin Zhang, Miao Liu, Tong Wu, Peng Xv, Jian Wang

“…ELISA and RT-qPCR were used to measure acetylcholine receptor antibody (AChR-Ab) and Th17-related cytokines, including IL-17, IL-21, IL-23, TNF-α, TGF-β, IL-1β, and IL-6. Western blot and immunofluorescence staining were used to detect the expression levels of key proteins and their phosphorylated forms, such as transforming growth factor beta-activated kinase 1 (TAK1), P38 mitogen-activated protein kinase (P38 MAPK), and eukaryotic initiation factor 4E (eIF-4E). …”
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COVID-19 vaccine uptake in Zimbabwe and Sierra Leone: an application of Health Belief Model constructs by Simon Ssentongo, Alex Muhereza, Morie Mustapha, Ruth Gemi, Dennis Cherian, Rebecca Waugh, Benjamin Crookston, Cougar Hall, Mary Linehan, Hayden Borg, Joshua West

“…Abstract Introduction While African countries, in general, experienced a milder COVID-19 impact compared to Western nations, they faced challenges with vaccine uptake. …”
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Evidence-based cancer care: assessing guideline adherence of multidisciplinary tumor board recommendations for breast and colorectal cancer in a non-academic medical center by Carl-Stephan Leonhardt, Leopold Lanzenberger, Raphael Puehringer, Ulla Klaiber, Irene Hauser, Oliver Strobel, Gerald Prager, Martin Bodingbauer

“…Yet, most patients in Western countries receive cancer care at non-academic medical centers. …”
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Debt Management and Financial Performance of SACCOs in Karamoja Region: A Case of Kamukoi, Thurr and Lotuke SACCOs. by Apio, Brenda

“…This study examined the effect of debt management on the financial performance of SACCOs in the western belt of the Karamoja sub-region. SACCO's financial performance in the region has been alarming. …”
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Care burden and quality of life among family caregivers of children with cerebral palsy in China: the mediating roles of social support and coping styles by Fang Liu, Rui Zhang, Cui Cui, Hengyu Zhou

“…Methods The purposive sampling method was used in this study to select 189 caregivers of cerebral palsy children from the rehabilitation department of a children’s hospital in western China from May 2022 to August 2023. Self-designed demographic data questionnaire, the WHO’s Quality of Life Questionnaire, the Zarit Burden Interview, the Social Support Rating Scale, and the Simplified Coping Style Questionnaire were used for conducting the investigation. …”
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The Role of Motility Impairment in the Pathogenesis of Functional Disorders of the Gastrointestinal Tract and Modern Possibilities for Their Treatment (Resolution of an Expert Coun... by I. V. Maev, A. S. Trukhmanov, A. A. Sheptulin, V. I. Simanenkov, S. R. Abdulhakov, N. A. Agafonova, V. A. Akhmedov, T. A. Ilchishina, M. G. Ipatova, O. V. Krapivnaya, Yu. A. Kucheryavyi, M. F. Osipenko, O. A. Storonova, G. N. Tarasova, G. Ya. Khismatullina, S. V. Cheryomushkin

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Principles of Rational Nutrition for Managing Constipation by Yu. O. Shulpekova, D. A. Sheptulin, N. V. Shulpekova

“…In countries characterized by the Western-style diet, only about 10% of people consume an optimal amount of fibre daily. …”
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Land use transition and its driving mechanisms in China’s human-elephant conflict areas by WANG Yuan, WANG Yahui, YANG Aoxi, FAN Hui, XIE Fei

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