The effects of citrulline supplementation on athlete´s performance: systematic review by Silvia Burgos, Aysu Dursun, Valentin Emilio Fernández Elias

“… Background: Citrulline is a non-essential amino acid that may enhance exercise performance and reduce soreness after exercise. …”
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How energy determines spatial localisation and copy number of molecules in neurons by Cornelius Bergmann, Kanaan Mousaei, Silvio O. Rizzoli, Tatjana Tchumatchenko

“…Our results further reveal robust energy benefits when certain mRNA classes are moved into dendrites, for example mRNAs of proteins with long amino acid chains or mRNAs with large non-coding regions and long half-lives proving surprising insights at the level of molecular populations.…”
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Sideroflexin family genes were dysregulated and associated with tumor progression in prostate cancers by Hua Huang, Huibo Lian, Wang Liu, Benyi Li, Runzhi Zhu, Haiyan Shao

“…Abstract Sideroflexin (SFXN) family genes encode for a group of mitochondrial proteins involved in cellular processes such as iron homeostasis, amino acid metabolism, and energy production. Recent studies showed that they were aberrantly expressed in certain human cancers. …”
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Advancing risk stratification in kidney transplantation: integrating HLA-derived T-cell epitope and B-cell epitope matching algorithms for enhanced predictive accuracy of HLA compa... by Matthias Niemann, Matthias Niemann, Benedict M. Matern, Benedict M. Matern, Gaurav Gupta, Bekir Tanriover, Fabian Halleck, Klemens Budde, Eric Spierings, Eric Spierings

“…Several algorithms of molecular compatibility have been suggested, each focusing on a specific aspect of epitope immunogenicity.MethodsConsidering reported death-censored graft survival in the SRTR dataset, we evaluated four models of molecular compatibility: antibody-verified Eplets, Snow, PIRCHE-II and amino acid matching. We have statistically evaluated their co-dependency and synergistic effects between models systematically on 400,935 kidney transplantations using Cox proportional hazards and XGBoost models.ResultsMultivariable models of histocompatibility generally outperformed univariable predictors, with a combined model of HLA-A, -B, -DR matching, Snow and PIRCHE-II yielding highest AUC in XGBoost and lowest BIC in Cox models. …”
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Case report: Hypoparathyroidism-sensorineural hearing loss-renal dysplasia without febrile seizures: a novel mutation in the GATA3 gene by Haibin Chen, Haibin Chen, Yudi Zhang, Xueyao Yang, Xueyao Yang, Yongzhen Li

“…This mutation resulted in the substitution of cysteine with phenylalanine at amino acid position 267 (p.C267F). The missense mutation was determined to be both pathogenic and novel.ConclusionEarly genetic testing should be prioritized, and regular monitoring of kidney development and hearing status is essential. …”
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Study on intestinal microbial communities of three different cattle populations on Qinghai-Tibet Plateau. by Quji Suolang, Zhuzha Basang, Wangmu Silang, Cangjue Nima, Qiwen Yang, Wa Da

“…KEGG enrichment analysis revealed that BL and TH cattle showed significant enrichment in the immune system, energy metabolism, and amino acid metabolism-related pathways compared with TJ cattle. …”
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Blueprint for a high-performance biomaterial: full-length spider dragline silk genes. by Nadia A Ayoub, Jessica E Garb, Robin M Tinghitella, Matthew A Collin, Cheryl Y Hayashi

“…Patterns of variation among sequence repeats at the amino acid and nucleotide levels indicate that the interaction of selection, intergenic recombination, and intragenic recombination governs the evolution of these highly unusual, modular proteins. …”
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Enhancement of postharvest performance in Lilium tigrinum Ker Gawl flowers with Salicylic acid: a signalling molecule and a growth regulator by Moonisah Aftab, Haris Yousuf Lone, Wajahat Waseem Tantray, Aijaz A. Wani, Mohmad Arief Zargar, Inayatullah Tahir

“…Furthermore, SA treatment enhances total soluble protein content, increased proline accumulation, decreased specific protease activity and maintained lower amino acid levels. These enhancements in physiological and biochemical stability can significantly enhance the economic viability of the floral industry by extending the postharvest longevity and maintaining the aesthetic integrity of cut flowers, thereby addressing the increasing global demand for superior-quality floral commodities. …”
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Guiding chili variety selection for Zao chili in Guizhou: Based on a systematic study of sensory, physicochemical, and volatile characteristics by Xueya Wang, Kuan Lu, Wenxin Li, Ju Chen, Yong Yin, Xiaojing Sun, Min Lu, Jianwen He

“…The ZC produced by FQB3 had the highest comprehensive sensory score (89.7), characterized by high total acid and amino acid nitrogen content and low crude fibre content. …”
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Distinct vaginal microbiome and metabolome profiles in women with preterm delivery following cervical cerclage by Jun Zhang, Li Li, Mengjun Zhang, Jiaoning Fang, Zhimin Xu, Yijing Zheng, Zhi Lin, Mian Pan

“…In addition, vaginal metabolomics-based liquid chromatography–Orbitrap–tandem mass spectrometry (LC-Orbitrap-MS/MS) found that the alteration in vaginal metabolites in pregnant women with PTB is involved in starch and sucrose metabolism; arginine and praline metabolism; galactose metabolism; purine metabolism; arginine metabolism; tryptophan metabolism and N-glycan biosynthesis; cysteine and methionine metabolism; taurine and hypotaurine metabolism; amino acid metabolism; propanoate metabolism; valine, leucine, and isoleucine biosynthesis; glycine, serine, and threonine metabolism; and steroid hormone biosynthesis. …”
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Actinorhodopsin: an efficient and robust light-driven proton pump for bionanotechnological applications by Nooraldeen Ayoub, Nadia Djabeur, Daniel Harder, Jean-Marc Jeckelmann, Zöhre Ucurum, Stephan Hirschi, Dimitrios Fotiadis

“…Here, we characterized the actinorhodopsin RlActR from the freshwater actinobacterium Rhodoluna lacicola, which conserves amino acid residues critical for light-driven proton pumping found in MRs. …”
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Integrated multi-omics analysis reveals the underlying molecular mechanism for the neurotoxicity of triclosan in zebrafish by Shasha Zhao, Yuhang Ling, Baohua Zhang, Danting Wang, Limei Sun

“…Lipid metabolism, especially glycerophospholipid metabolism, and amino acid regulation pathways were co-enriched by multi-omics combinatorial analysis. …”
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Gut microbiota dysfunction in Crohn’s disease by Sylvie Buffet-Bataillon, Sylvie Buffet-Bataillon, Gabriela Durão, Isabelle Le Huërou-Luron, Olivier Rué, Olivier Rué, Yann Le Cunff, Vincent Cattoir, Guillaume Bouguen

“…Major shifts in oxidative stress pathways and reduced carbohydrate and amino acid metabolism in favour of nutrient transport were identified in CS compared to CR. …”
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Analysis and Characterization of the Immunogenicity of Rhoptry Protein 18 by Masoud Foroutan, Amir Karimipour-Saryazdi, Ali Dalir Ghaffari, Hamidreza Majidiani, Arezo Arzani Birgani, Elaheh Karimzadeh-Soureshjani, Shahrzad Soltani, Hany M Elsheikha

“…The Ramachandran plot of both crude and refined models showed that 85.8% and 95.3% of the amino acid residues, respectively, fell within favored regions, indicating energetically stable conformations. …”
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A novel protein encoded by porcine circANKRD17 activates the PPAR pathway to regulate intramuscular fat metabolism by Xiao He, Fang Xie, Ying Nie, Xuefeng Wang, Junyi Luo, Ting Chen, Qianyun Xi, Yongliang Zhang, Jiajie Sun

“…In addition, we discovered that circANKRD17 has an open reading frame and can be translated into a novel 571-amino-acid protein that promotes lipid metabolism. Conclusions Our research provides new insights into the role of protein-coding circANKRD17, especially concerning the metabolic characteristics of pig breeds with higher intramuscular fat content.…”
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Design, theoretical approaches and new framework of pyrazolo[3,4-d]pyrimidine as potent anticancer agents: Efficient synthesis, ADME-T and molecular docking by Peduri Suresh Reddy, Thuraka Sekhar, Pinnu Thriveni, Gandla Mahesh Kumar, Allaka Tejeswara Rao, Mohammad Raish, Tota Giridhar, Gudipati Srinivasulu

“…Additionally, the anchoring function of the 1,3,4-thiadiazole-substituted pyrazolo[3,4-d]pyrimidine moiety in interacting with anticancer targets and hydrophobic interaction with the essential amino acid residues has been highlighted by molecular modeling studies. …”
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Creatine and pregnancy outcomes, a prospective cohort study in low-risk pregnant women: study protocol by Deborah L De Guingand, Stacey J Ellery, Miranda L Davies-Tuck, Hayley Dickinson

“…This circuit is fuelled by creatine, an amino acid derivative that can be obtained from a diet containing animal products, and by synthesis in the body de novo. …”
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Analysis of expression and transport activity of sugar transporter gene HpSWEET7 from red pitaya by ZHENG Qianming, YAN Shuang, XIE Pu, WANG Honglin, MA Yuhua

“…[Results] The ORF of HpSWEET7 was 771 bp, encoding 256 amino acid residues. HpSWEET7 contained two MtN3_saliva (Pfam No. …”
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Genome-wide identification and expression analysis of the PIN gene family in the pepper pedicel abscission zone and during root development by HE Lei, YAN Xi, LAI Wei, LIU Chongzheng, YANG Hong, HE Jianwen

“…The proteins encoded by these genes exhibit amino acid length ranging from 358 to 654 residues, molecular weight from 39 251.05 D to 71 170.91 D, and isoelectric point from 6.40 to 9.38. …”
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Evaluating the reflux suppression properties of Gaviscon Infant powder with different milk formulations using an in vitro model of the infant stomach by Fiona McLaughlin, Jeanine Fisher, Mark Atherton, Cathal Coyle

“…Various milk formulations are commercially available to help manage GER and CMPA symptoms (extensively hydrolyzed [eHF], partially hydrolyzed [pHF], and amino-acid formulas [AAF]). We aimed to understand if an alginate product (Gaviscon Infant powder) worked as intended in the presence of different milk formulations. …”
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