An Electronic Frailty Index Based on Deficit Accumulation May Predict Glaucomatous Visual Field Progression by Duy W, Pajewski N, Williamson JD, Thompson AC

“…Walter Duy,1,* Nicholas Pajewski,2 Jeff D Williamson,3 Atalie C Thompson3,4,* 1Wake Forest University School of Medicine, Winston-Salem, NC, USA; 2Department of Biostatistics and Data Science, Wake Forest University School of Medicine, Winston-Salem, NC, USA; 3Department of Gerontology and Geriatric Medicine, Wake Forest University School of Medicine, Winston-Salem, NC, USA; 4Department of Surgical Ophthalmology, Wake Forest University School of Medicine, Winston-Salem, NC, USA*These authors contributed equally to this workCorrespondence: Atalie C Thompson, Department of Surgical Ophthalmology, Atrium Health Wake Forest Baptist Health, Janeway Tower 6th Floor, Winston-Salem, NC, USA, Tel +1 (336) 716-4091, Fax +1 (336) 716-7994, Email [email protected]: To investigate whether an electronic frailty index (eFI) is associated with visual field loss in glaucoma.Patients and Methods: We identified 1163 subjects ≥ 65 years old with glaucoma (1082 right eyes and 1042 left eyes) who had a calculable baseline eFI, and who had reliable visual fields at baseline and final follow-up. …”
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Impact of Oxycodone HCl Extended-release Formulary Restrictions on Extended-release Opioid Market Share, Healthcare Resource Utilization and Costs in Commercial and Medicare Plans by Rolin L. Wade, Chi-Chang Chen, Ajita P. De, Jaren C. Howard

“…**Background:** Previous research demonstrated that utilization management (UM) such as prior authorization (PA) or non-formulary (NF) restrictions may reduce pharmacy costs when designed and applied appropriately to certain drug classes. …”
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The Landing Error Scoring System (LESS) and Lower Limb Power Profiles in Elite Rugby Union Players by Stephen Rowell, Nicola Relph

“…LESS trials were scored independently by the authors. Statistical analyses were used to confirm reliability, data normality, and between group differences (p<0.05)…”
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“Panoramas magníficos”. La geografía en tres revistas guatemaltecas, 1894-1898 by Rodrigo Antonio Vega y Ortega Báez

“…The research methodology takes up the social studies of science that make it possible to relate the history of geography with the interest of editors, authors and readers for this science. The journals included geographical themes because it was a useful science in political, social and economic terms, as well as having a place in formal education and informal education.…”
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Health-Related Quality of Life and Psychological Outcomes in Participants with Symptomatic and Non-Symptomatic Knees after ACL Reconstruction by Johanna M. Hoch, Ansley Swann, Rachel Kleis, Matthew C. Hoch, Carrie Baker, Dee Dlugonski

“… # Purpose/Hypothesis The purpose of this study was to examine differences in health-related quality of life (HRQL) and psychological outcomes in people with a history of ACLR who were categorized as symptomatic or non-symptomatic by application of the Englund criteria. The authors’ hypothesized participants classified as symptomatic would have lower HRQL, increased fear-avoidance beliefs, and decreased resilience compared to participants classified as non-symptomatic…”
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Reliability of the Tuck Jump Assessment Using Standardized Rater Training by Kevin Racine, Meghan Warren, Craig Smith, Monica R. Lininger

“… # HYPOTHESIS/PURPOSE To determine the reliability of the TJA using varied healthcare professionals following an online standardized training program. The authors hypothesized that the total score will have moderate to excellent levels of intra- and interrater reliability…”
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Genome Characteristic of NDM-5-Producing Klebsiella Quasipneumoniae and Klebsiella Pneumoniae in China by Chen L, Liu R, Ye H, Qian J, Lou D

“…Lifeng Chen,1,&ast; Ruishan Liu,2,3,&ast; Haowei Ye,2 Jiajie Qian,4 Danfeng Lou5 1Department of Clinical Engineering and Materials Supplies, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, People’s Republic of China; 2State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, People’s Republic of China; 3Jinan Microecological Biomedicine, Shandong Laboratory, Jinan, People’s Republic of China; 4Department of Gastrointestinal Surgery, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, People’s Republic of China; 5Department of Infectious Diseases, Shulan (Hangzhou) Hospital, Hangzhou, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Danfeng Lou, Department of Infectious Diseases, Shulan (Hangzhou) Hospital, No. 848 Dongxin Road, Hangzhou, People’s Republic of China, Email [email protected] Jiajie Qian, Department of Gastrointestinal Surgery, The First Affiliated Hospital, College of Medicine Zhejiang University, No. 79 Qingchun Road, Hangzhou, People’s Republic of China, Email [email protected]: The global dissemination of carbapenem-resistant Enterobacteriaceae poses a significant threat to public health. …”
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Enhancing privacy and traceability of public health insurance claim system using blockchain technology by Andry Alamsyah, I. Putu Sadhu Setiawan

“…A proof-of-concept prototype was developed to demonstrate the core functionalities of the new system.ResultsBy integrating blockchain technology, our prototype ensures authorized access, bolsters data privacy, and maintains data integrity in the NHI claim workflow. …”
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Refining management strategies for Lennox–Gastaut syndrome: Updated algorithms and practical approaches by Stéphane Auvin, Alexis Arzimanoglou, Mercè Falip, Pasquale Striano, J. Helen Cross

“…Most people with LGS have learning difficulties and need a lot of support, often in residential care. The authors are experts in treating people with LGS and this article provides up‐to‐date guidance and advice on how best to care for those with the condition.…”
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Causal Effects of Sleep Traits on Angina Pectoris: Mediation by Cardiovascular Risk Factors by Zeng C, Ke Y, Li H, Zhang C, Chen J, Chen M

“…Chuanfei Zeng,&ast; Yujia Ke,&ast; Huan Li, Chi Zhang, Jian Chen, Mingkai Chen Department of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan, Hubei, 430000, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Mingkai Chen, Email [email protected]: Angina pectoris (AP) is a major factor in heightened risk of cardiac arrest and has been previously linked to sleep patterns. …”
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Impacts of National Reimbursement Drug Price Negotiation on drug accessibility, utilization, and cost in China: a systematic review by Zheng Zhu, Jiawei Zhang, Zhihu Xu, Quan Wang, Yu Qi, Li Yang

“…The published studies indicated the implementation of the NRDPN policy decreased drug prices, ranging from 24 to 72%, which increased the affordability of success-negotiated drugs (refer to those medications that have undergone a successful price negotiation process between pharmaceutical companies and healthcare authorities) and decreased out-of-pocket expenditures. …”
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DEVELOPING INFORMATION AND TECHNOLOGICAL COMPETENCE OF PROSPECTIVE MILITARY SAILORS by Ruslan Shevchenko, Oleh Cherniavskyi, Vasyl Shemchuk, Olena Zlobina, Natalia Benkovska, Nataliia Terentieva, Андрій Гуралюк

“…In the research proposed by the authors, the components of the information technology competence of future officers of the Armed Forces of Ukraine are revealed. …”
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The Role of Fatigue in Return to Sport Testing Following Anterior Cruciate Ligament Reconstruction by Justin C Tallard, Corbin Hedt, Bradley S Lambert, Patrick C McCulloch

“… # Purpose/Hypothesis The purpose of this study was to assess the effect of fatigue on performance of various hop tests used in clinical rehabilitation settings by examining LSI scores. The authors hypothesized that participants will have worse limb symmetry index scores following the fatigue protocol and that the operative limb (ACLR) will have a greater decline in function than the non-operative limb (CON)…”
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Barriers and enablers to implementing clinical practice guidelines in primary care: an overview of systematic reviews by Tao Wang, Xian-Liang Liu, Jing-Yu (Benjamin) Tan, Isabella Zhao

“…Objectives To identify the barriers and enablers to implementing clinical practice guidelines (CPGs) recommendations in primary care and to provide recommendations that could facilitate the uptake of CPGs recommendations.Design An overview of systematic reviews.Data sources Nine electronic databases (PubMed, Cochrane Library, CINAHL, MEDLINE, PsycINFO, Web of Science, Journals @Ovid Full Text, EMBase, JBI) and three online data sources for guidelines (Turning Research Into Practice, the National Guideline Clearinghouse and the National Institute for Health and Care Excellence) were searched until May 2021.Eligibility criteria Systematic reviews, meta-analyses or other types of systematic synthesis of quantitative, qualitative or mixed-methods studies on the topic of barriers and/or enablers for CPGs implementation in primary care were included.Data extraction and synthesis Two authors independently screened the studies and extracted the data using a predesigned data extraction form. …”
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Impact of Preoperative Daytime Sleepiness and Insomnia on Therapy Adherence and Neurostimulation Amplitude in Unilateral Hypoglossal Nerve Stimulation by Pordzik J, Ludwig K, Ruckes C, Gouveris H

“…Johannes Pordzik,1,&ast; Katharina Ludwig,1,&ast; Christian Ruckes,2 Haralampos Gouveris1 1Department of Otolaryngology/Head and Neck Surgery & Sleep Medicine Center, University Medical Center Mainz, Mainz, 55131, Germany; 2Interdisciplinary Center for Clinical Trials, University Medical Center Mainz, Mainz, 55131, Germany&ast;These authors contributed equally to this workCorrespondence: Haralampos Gouveris, Email [email protected]: Average adherence to hypoglossal nerve stimulation (HGNS) therapy is more than 5 h/night. …”
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Arsitektur Sistem Percakapan Otomatis Berbahasa Indonesia dengan Normalisasi Bahasa Informal Menjadi Baku by Muhammad Fathur Rahman Khairul, Rizal Setya Perdana

“…NLP generally only works with formal language and is unable to interpret the meaning of informal sentences. Therefore, the authors propose an approach to enable machines to understand informal language by normalizing the informal language to standard by utilizing NLP. …”
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Peningkatan Akurasi Klasifikasi Algoritma C 4.5 Menggunakan Teknik Bagging pada Diagnosis Penyakit Jantung by Erwin Prasetyo, Budi Prasetiyo

“…Heart disease data is taken from the UCI Machine Learning Repository dataset. The purpose of the authors conducting this research is to determine the application of bagging techniques on the C4.5 algorithm, determine the accuracy of the results in the C4.5 algorithm, and compare the level of accuracy of the application of bagging techniques on the C4.5 algorithm. …”
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Shoulder Isokinetic Strength Balance Ratio in Overhead Athletes: A Cross-Sectional Study by Valentine Zimermann Vargas, Caroline Motta, Rodrigo Luiz Vancini, Claudio Andre Barbosa de Lira, Marilia Santos Andrade

“…As there were several differences between the overhead sports according to the FRs, the authors suggest caution in grouping overhead athletes across multiple sports. …”
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Perancangan User Experience Aplikasi Info COVID-19 Menggunakan Metode Human Centered Design by Pradya Mutiarahma, Hanifah Muslimah Az-Zahra, Yusi Tyroni Mursityo

“…Based on that problem, the author provides a solution by designing the user experience of a mobile-based application for COVID-19 information. …”
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B Cell Activation, Differentiation, and Their Potential Molecular Mechanisms in Osteoarthritic Synovial Tissue by Lu P, Li Y, Yang S, Yao H, Tu B, Ning R

“…Peizhi Lu,1,2,&ast; Ya Li,1,2,&ast; Shuo Yang,2 Haoyu Yao,2 Bizhi Tu,2 Rende Ning1,2 1Graduate School, Bengbu Medical University, Bengbu, Anhui, People’s Republic of China; 2Department of Orthopedics, the Third Affiliated Hospital of Anhui Medical University, the First People’s Hospital of Hefei, Hefei, Anhui, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Bizhi Tu, Department of Orthopedics, the Third Affiliated Hospital of Anhui Medical University, the First People’s Hospital of Hefei, Hefei, Anhui, People’s Republic of China, Tel +86 15357483840, Email [email protected] Rende Ning, Graduate School, Bengbu Medical University, Bengbu, Anhui, People’s Republic of China, Tel +86 13956966305, Email [email protected]: The objective of this study was to characterize the activation and differentiation of B cells in the synovium of osteoarthritis (OA) and to explore the underlying molecular mechanisms.Methods: Peripheral blood and synovial samples from OA patients at different stages were collected, and flow cytometry was employed to analyze the activation and differentiation of B cells. …”
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