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Subwavelength-scale off-axis optical nanomanipulation within Gaussian-beam traps
Published 2025-01-01Get full text
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282
Impact of corticosteroids on the efficacy of first-line pembrolizumab plus chemotherapy in patients with advanced non-small-cell lung cancer
Published 2025-02-01“…Results: Of the 193 included patients, 43 (22.3%) were receiving SCs, mainly because of symptomatic brain metastases (in 25/43 cases, 58%). In multivariate analysis, SC therapy at a 10 mg/day threshold was not associated with PFS (hazard ratio (HR) = 1.25, 95% confidence interval (CI) 0.77–2.03, p = 0.35). …”
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Pooled screening for CAR function identifies novel IL-13Rα2-targeted CARs for treatment of glioblastoma
Published 2025-02-01“…Nonetheless, they are of particular interest for the treatment of glioblastoma, which is an aggressive form of brain cancer with few effective therapeutic options, due to their ability to cross the highly selective blood-brain barrier.Methods Here, we use our pooled screening platform, CARPOOL, to expedite the discovery of CARs with antitumor functions necessary for solid tumor efficacy. …”
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Multi-dimensional evidence from the UK Biobank shows the impact of diet and macronutrient intake on aging
Published 2025-02-01“…MVMR results confirm the causal benefits of carbohydrate intake, including reductions in phenotypic age (β = −0.0025; 95% CI = [−0.0047, −0.0003]; p = 0.0253) and increases in whole-brain grey matter volume (β = 0.0262; 95% CI = [0.007, 0.046]; p = 0.0087). …”
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287
Ultrahigh-field imaging (7 Tesla) in DNET: Unmasking microstructural imaging characteristics – A case report
Published 2025-03-01“…Commercial ultrahigh-field 7 Tesla (T) MRI has been approved for clinical brain imaging, including applications in epilepsy and brain tumors. …”
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288
Identification of m6A methyltransferase-related WTAP and ZC3H13 predicts immune infiltrates in glioblastoma
Published 2025-02-01“…Abstract Glioblastoma (GBM) is a prevalent and highly fatal primary malignant brain tumor. N6-methyladenosine (m6A) modification plays a critical role in the development of brain tumor. …”
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A new effLuc/Kate dual reporter allele for tumor imaging in mice
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291
The Impact of Drug Abuse on The Learner's Academic Performance in Kisoro Municipality Kisoro District.
Published 2024“…The study recommended that students should reduce and if possible abstain from drugs taking if they are to keep track of education well and improve their academic performance, the government should intervene by putting strict laws on the way sellers of drugs should put the time to open their bars and to close them to reduce on drugs taking among people, students should look for other ways of reducing stress not to end it by drugs taking since it affects their brain and also affects their academic performance, students' leisure time should be spent productively on doing some activities like reading and discussing but not to spend it on drugs abusing if they are to move forward effectively with the education process and there should be massive sensitization on the dangers of drugs on academic performance of students to reduce and if possible end drugs taking among school learning children.…”
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292
Facts About Iron
Published 2017-11-01“…Iron also is needed to keep the immune system healthy and help brain cells work normally. This 2-page fact sheet is a minor revision written by Linda B. …”
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293
THE HEALING POWER OF MUSIC. MUSIC IN PRACTICE
Published 2012-06-01“…Their knowledge is indispensable in order to be able to approach the psychology of hearing, of sound and music psychology. The brain research conducted in the second half of the 20th century has demonstrated the fact that the right hemisphere is the one responsible for music: it has the functions of recognizing melody, while the left one to identify rhythm. …”
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294
Leveraging AlphaFold for innovation and sustainable health research in Africa
Published 2025-02-01“…Without addressing the lack of research infrastructure, funding, and supportive science policies, structural biology capacity-building efforts in Africa will continue to be hindered by the persistent challenge of brain drain.…”
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295
INTERROGATING ISSUES AND PERSPECTIVES ON RESEARCH AND DEVELOPMENT IN SELECTED NIGERIAN PUBLIC UNIVERSITIES
Published 2023-08-01“…The paper identified inadequate funding, lack of equipment, facilities and materials, lack of awareness, lack of implementation of research results, low rating in human capital indices, brain-drain, underemployment, etc, as challenges of research and human capital development in Nigeria. …”
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296
Atypical early neural responses to native and non-native language in infants at high likelihood for developing autism
Published 2025-02-01“…Infants were presented with native (English) and novel (Japanese) speech while sleeping naturally in the scanner. Whole-brain and a priori region-of-interest analyses were conducted to evaluate neural differences in language processing based on likelihood group and language condition. …”
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Acute effects of physical exercise on cognitive function and neurotrophins in patients with type 1 diabetes: A systematic review
Published 2025-02-01“…In contrast, higher levels of neurotrophins, such as brain-derived neurotrophic factor (BDNF), may be associated with better brain health. …”
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299
Behavioral representations within the endogenous dual attentional pathways during audiovisual integration processing
Published 2025-02-01“…The brain showed consistent activation in the frontal eye field, inferior parietal lobule, supplementary motor area, superior temporal gyrus, middle occipital gyrus and cuneus. …”
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Estimation of median LC50 and toxicity of environmentally relevant concentrations of thiram in Labeo rohita
Published 2025-02-01“…Moreover, comet assay revealed significant (p < 0.05) DNA damage in the isolated cells of kidneys, heart and brain at higher doses (80 μg/L and 120 μg/L) of thiram that was further confirmed by histo-pathological alterations in these tissues. …”
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