Statistical and machine learning based platform-independent key genes identification for hepatocellular carcinoma. by Md Al Mehedi Hasan, Md Maniruzzaman, Jie Huang, Jungpil Shin

“…Hepatocellular carcinoma (HCC) is the most prevalent and deadly form of liver cancer, and its mortality rate is gradually increasing worldwide. …”
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Perceptions of Biosimilars Among Healthcare Providers in Saudi Arabia by Mohammed Alqahtani, Ahmed Al-jedai, Albert Wertheimer

“…Biosimilars are safe and effective treatments for chronic diseases such as cancer and rheumatoid arthritis. The Saudi Food and Drug Authority (SFDA) manages the quality and registration of biosimilars in the Kingdom of Saudi Arabia. …”
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Liver Transplantation in the Treatment of Unresectable Hepatocellular Carcinoma in the Absence of Liver Cirrhosis by O. D. Olisov, M. S. Novruzbekov, I. E. Galankina, L. N. Zimina, V. A. Gulyaev, L. V. Donova, M. Sh. Khubutiya

“…Hepatocellular carcinoma is one of the most common types of cancer, which occurs mainly in patients with liver cirrhosis and chronic viral hepatitis. …”
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A Criterion-based Approach for the Systematic and Transparent Extrapolation of Clinical Trial Survival Data by Gabriel Tremblay, Patrick Haines, Andrew Briggs

“…The techniques are then applied to a metastatic breast cancer (MBC) example. **Methods:** A criterion-based guide was devised to allow the accurate extrapolation and justification of survival estimates in a MBC study comparing eribulin (Halaven) monotherapy with treatment of their (patient’s) physician’s choice (TPC). …”
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Candida dubliniensis breast implant infection in a lung transplant recipient by Ashley Barnes, MD, Kristen Broderick, MD, Errol Bush, MD, Jonathan Orens, MD, Melanie Marashly, CRNP, Shmuel Shoham, MD, Robin Avery, MD

“…This report details the case of a lung transplant recipient with a remote history of breast cancer and breast reconstruction with implants, who received lengthy antifungal therapy for a post-transplant donor-transmitted Candida dubliniensis empyema. …”
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A systematic review of proaporphine alkaloids and a pharmacological update by Christian Bailly

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Nanozyme-based aptasensors for the detection of tumor biomarkers by Ke Wang, Xiaogang Lin, Xiao Lv, Mingna Xie, Jinyu Wu, Jie Jayne Wu, Yang Luo

“…The objective is to provide insights for improving biosensor performance in tumor biomarker detection, thereby contributing to advancements in precision cancer diagnosis and treatment.…”
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An aggregation-induced emission-active lysosome hijacker: Sabotaging lysosomes to boost photodynamic therapy efficacy and conquer tumor therapeutic resistance by Hang Zou, Pingping Wang, Zhihao Bai, Liping Liu, Jingtong Wang, Yanfang Cheng, Bairong He, Zujin Zhao, Lei Zheng

“…Therapeutic resistance is a major challenge in clinical cancer theranostics, often leading to treatment failure and increased patient mortality. …”
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Evaluating the World Health Organization’s Hearts Model for Hypertension and Diabetes Management: A Pilot Implementation Study in Guatemala by Irmgardt Alicia Wellmann, Luis Fernando Ayala, Taryn M. Valley, Vilma Irazola, Mark D. Huffman, Michele Heisler, Peter Rohloff, Rocío Donis, Eduardo Palacios, Manuel Ramírez-Zea, David Flood

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The emerging roles of aberrant alternative splicing in glioma by Reda Ben Mrid, Sara El Guendouzi, Marco Mineo, Rachid El Fatimy

“…Such disruptions are usually associated with the development of several cancers, including glioma. Consequently, AS constitutes a key regulatory mechanism that could serve as a target for future therapies. …”
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A review of research progress on disease burden of foodborne aflatoxins by Mei QIN, Jinyao CHEN, Lishi ZHANG, Jiao HUO, Yang SONG, Li CHENG

“…The International Agency for Research on Cancer (IARC) has classified AFB1, AFB2, AFG1 and AFG2 as Group 1 carcinogens, primarily causing hepatocellular carcinoma (HCC) in humans, but also affecting growth and development in children and damaging the human immune system, resulting in varying degrees of health burden to populations. …”
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Role of alpha-fetoprotein in complex diagnostics of progressing course of chronic hepatitis B and C by I. A. Belavina, O. P. Dudanova

“…Overall 69 patients with chronic viral hepatitis were investigated: 39 with chronic hepatitis B (CHB) and 30 — with chronic hepatitis C (CHC) without signs of cirrhotic transformation and liver cancer. The diagnosis was verified by clinical, laboratory and morphological – with assessment of histological activity index (HAI) and histological sclerosis index (HSI), instrumental (transabdominal ultrasound, Doppler ultrasonography of portal blood flow), virologic studies. …”
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Failure of Colorectal Anastomosis: Risk Factors, Prevention, Diagnosis, Therapeutic Tactics by M. F. Cherkasov, A. V. Dmitriev, V. S. Groshilin, S. V. Pereskokov, M. A. Kozyrevskiy, A. A. Urupina

“…Individual consideration of risk factors and their adequate assessment in terms of possible complications are decisive in the choice of the extent of surgical intervention, which will undoubtedly improve the immediate and long-term results of the surgical treatment of colorectal cancer.…”
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The 500-year Cultural & Economic Trajectory of Tobacco: A Circle Complete by Christopher A. Jones, Amanda Wassel, William Mierse, E. Scott Sills

“…Solid epidemiological work connecting tobacco use with “the shortening of life span” began to appear in the medical literature in the 1950s, linking smoking with lung cancer and related conditions. In subsequent years, these developments led to significant curtailment of tobacco use. …”
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An overview of bioactive components and phytopharmaceutical potentials of Hygrophila auriculata–A herbaceous medicinal plant by Megha Malpotra, Meenakshi Garg, Neha Singh, Susmita Dey Sadhu, Rajni Chopra, Bhupesh Sharma

“…The bioactive compounds are linked to phytopharmaceutical properties like antioxidant, cardioprotective, anti-diabetic, diuretic, hepatoprotective, androgenic, haematinic, anti-cancer, anti-inflammatory, etc. However, more research is still needed to connect existing literature with contemporary pharmacology. …”
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Endometriosis in Postmenopausal Woman Without Previous Hormonal Therapy: A Case Report by Mine İslimye Taşkın, Meltem Çağrı Menteşe, Engin Uzgören, Ümit İnceboz

“…A pelvic ultrasound scan revealed a right ovarian cystic mass of approximately 2.6x2.1cm in size and a left ovarian multiple lobated hemorrhagic cystic mass approximately 5.0x2.8 cm in size. Cancer antigen 25 (CA 125) level appeared to be within the normal range. …”
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Helicobacter pylori Infection and Hepatobiliary Pathology by S. V. German, I. P. Bobrovnitsky

“…Different species of the Helicobacter genus, including H. pylori, are shown to contribute to the development of liver cancer. However, some researchers report data against the involvement of H. pylori in the pathogenesis of various hepatobiliary diseases.Conclusion.  …”
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Effect of Dietary Inclusion of Chitosan on Survival and Selected Cellular Antioxidants in <i>Drosophila melanogaster</i> by O.G. Igharo, L.I. Abadaike, J.O. Osunbor, I.C. Owie, A.I. Aruomaren, E.L. Igharo, K.I. Ikeke

“…Reduced antioxidant levels have been linked to accelerated aging and conditions leading to death like cancer. Based on the fact that antioxidant slow aging process and reduces risks of life threatening conditions. …”
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Halodule uninervis extract facilitates the green synthesis of gold nanoparticles with anticancer activity by Nadine Wehbe, Joelle Edward Mesmar, Riham El Kurdi, Ali Al-Sawalmih, Adnan Badran, Digambara Patra, Elias Baydoun

“…The produced AuNPs exhibited anticancer activity against several human cancer cell lines, highlighting their potential efficacy as anticancer therapeutic agents. …”
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