Immunoinformatic strategy for developing multi-epitope subunit vaccine against Helicobacter pylori. by Md Nahian, Md Rasel Khan, Fabiha Rahman, Hossain Mohammed Reza, Imren Bayil, Tanjum Ahmed Nodee, Tabassum Basher, Mostafizur Rahaman Sany, Rabeya Najnin Munmun, S M Ariful Habib, Lincon Mazumder, Mrityunjoy Acharjee

“…Helicobacter pylori is a gram-negative bacterium that persistently infects the human stomach, leading to peptic ulcers, gastritis, and an increased risk of gastric cancer. The extremophilic characteristics of this bacterium make it resistant to current drug treatments, and there are no licensed vaccines available against H. pylori. …”
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Towards autonomous robotic THz-based in vivo skin sensing: the PicoBot by Anubhav Dogra, Dominic Jones, Arturo Ignacio Hernandez Serrano, Shruti Chakraborty, Jacob Joshua Young, Benjamin George Page, Joseph Hardwicke, Pietro Valdastri, Emma Pickwell-MacPherson

“…Skin conditions including eczema, psoriasis and skin cancer affect a high percentage of the population and we have been developing a THz probe to help with their diagnosis, treatment and management. …”
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Pathogenic and therapeutic role of bile acids at reflux-gastritis by T. L. Lapina, I. M. Kartavenko, V. T. Ivashkin

“…According to the modern point of view bile acids are associated with a lot of neoplasms of digestive organs, including esophageal, stomach, small intestine, liver, pancreas and colorectal cancer. Exposition of bile acids results in formation of active forms of oxygen and nitrogen, damage of DNA, mutagenicity, induction of apoptosis in short-term prospect and resistance to apoptosis in long-term prospect. …”
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Local control and recurrence patterns after stereotactic irradiation delivered in more than 4 fractions for hepatocellular carcinomas and liver metastases: a retrospective study by Alizée Renan, Marie Bruand, Maria Jolnerovski, Aboubacar Diallo, Nicolas Demogeot

“…Results The primary dose ranged from 35 to 50 Gy delivered in 5 to 7 fractions for the treatment of HCC (39%) or liver metastases (61%) mainly secondary to colorectal cancer (40%). LC rate was 64%, with 12 patients showing recurrence volume overlap with the initial target volume or treatment isodose. …”
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Targeting MDM2 affects spastin protein levels and functions: implications for HSP treatment by Francesca Sardina, Federica Polverino, Sonia Valentini, Claudia Carsetti, Elisabetta Falvo, Giada Tisci, Silvia Soddu, Fabiola Moretti, Alessandro Paiardini, Cinzia Rinaldo

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The Effect of Tumor Angiogenesis Agents on Tumor Growth Dynamics: A Mathematical Model by Ali Mohseni, Mohammad Pooyan, Somayeh Raiesdana, Mohammad Bagher Menhaj

“…In this paper, we developed a cancer model by introducing tumor angiogenesis agents to better highlight the role of these chemical substances in tumor-induced vascularization. …”
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Burden of HPV-induced diseases and cost effectiveness of catch-up vaccination in Czech Republic: a model-based study by Vojtech Kamenský, Lukáš Dostálek, Martin Rožánek, Aleš Tichopád, Roman Prymula, Ivana Šarkanová

“…Abstract Objectives Human papillomavirus (HPV) infections are highly prevalent sexually transmitted infections, notably associated with various cancers. This study analyses the health and economic impacts of HPV-associated diseases in the Czech Republic and evaluates the cost-effectiveness of a catch-up vaccination program. …”
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Lower urinary dysfunction as a long-term effect of childhood vincristine treatment, with potential influences by sex and dose by Nao Iguchi, Ali Teimouri, Duncan T. Wilcox, Anna P. Malykhina, Nicholas G. Cost

“…Abstract Vincristine (VCR) is one of the most widely used chemotherapy agents in treating pediatric cancer. Nonetheless, it is known to cause dose-dependent neurotoxicity which can impact virtually every organ system. …”
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Bidirectional regulation of reactive oxygen species for radiosensitization in nasopharyngeal carcinoma by Jie Chen, Chengyu Feng, Yufei Lan, Xiangtian Chen, Zhengqi Peng, Zihan Huang, Ruiqing Wang, Wenxin Zhang, Yingying Ye, Zhilei Mao, Dongyue Pan, Lihua Yang

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International accreditation of a pediatric hematology/oncology fellowship program in Guatemala: a quantitative assessment by Daniel C. Moreira, Claudia Garrido, Roy Rosado, Leeanna Fox Irwin, Ricardo Mack, Carlos Rodriguez-Galindo, Federico Antillón-Klussmann

“…Abstract Purpose High-quality graduate medical education programs are essential to expand the care available to children with cancer worldwide. The authors used the Education Program Assessment Tool (EPAT), a standardized tool for evaluating pediatric hematology/oncology (PHO) fellowship programs, to describe the impact of the Accreditation Council for Graduate Medical Education International (ACGME-I) accreditation process. …”
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Digital twins as global learning health and disease models for preventive and personalized medicine by Xinxiu Li, Joseph Loscalzo, A. K. M. Firoj Mahmud, Dina Mansour Aly, Andrey Rzhetsky, Marinka Zitnik, Mikael Benson

“…Early clinical applications of DTs have shown potential in areas like artificial organs, cancer, cardiology, and hospital workflow optimization. …”
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A Cost-effectiveness Analysis of Brentuximab Vedotin in Relapsed or Refractory Systemic Anaplastic Large Cell Lymphoma by Margaret Hux, Denise Zou, Esprit Ma, Peter Sajosi, Andreas Engstrom, Ross Selby, Eugene Benson, Andrew Briggs, Vijayveer Bonthapally

“…Comparison with conventional chemotherapy was based on data from the Canadian British Columbia Cancer Agency registry from 40 patients starting salvage chemotherapy after front-line treatment between 1980 and 2012. …”
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Comparative analysis of alectinib and brigatinib in real-world treatment of advanced NSCLC with ALK rearrangements by Kyuhwan Kim, Kyu Yean Kim, Hye Seon Kang, Ah Young Shin, Sung Kyoung Kim, Chan Kwon Park, Sang Haak Lee, Seung Joon Kim, Jeong Uk Lim, Chang Dong Yeo

“…Background and objectives: This study aimed to compare the efficacy of the second-generation anaplastic lymphoma kinase (ALK) tyrosine kinase inhibitors (TKIs) alectinib and brigatinib in the treatment of advanced non-small-cell lung cancer (NSCLC) with ALK rearrangements based on real-world data. …”
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Biological age model using explainable automated CT-based cardiometabolic biomarkers for phenotypic prediction of longevity by Perry J. Pickhardt, Michael W. Kattan, Matthew H. Lee, B. Dustin Pooler, Ayis Pyrros, Daniel Liu, Ryan Zea, Ronald M. Summers, John W. Garrett

“…Age- and sex-corrected survival hazard ratio for the highest-vs-lowest risk quartile was 8.73 (95% CI,8.14-9.36) for the CT biological age model, and increased to 24.79 after excluding cancer diagnoses within 5 years of CT. Muscle density, aortic plaque burden, visceral fat density, and bone density contributed the most. …”
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Solitary metastasis in the internal auditory canal from non-small cell lung carcinoma: A case report by Julie De Boos, Marie Bruyneel, Ionela Bold

“…Discussion: IAC metastases are rare, representing only 0.3%–0.7 % of all lesions in this anatomical space. Lung cancer is a common primary source. Clinically, IAC metastases manifest with acute onset and rapid symptom progression, often mimicking benign conditions. …”
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Budget Impact of RefluxStop™ as a Treatment for Patients with Refractory Gastro-oesophageal Reflux Disease in the United Kingdom by Sam Harper, Lukasz Grodzicki, Stuart Mealing, Elizabeth Gemmill, Paul Goldsmith, Ahmed Ahmed

“…**Discussion:** While the time horizon was too short to capture some of the adverse events of PPIs and complications of GORD, such as the development of Barrett’s esophagus or esophageal cancer, the use of RefluxStop™ was associated with a substantial reduction in surgical complications, including surgical failures, reoperations, and endoscopic esophageal dilations. …”
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Assessment of Radionuclide Concentration in Surface Soil and Human Health Risk Associated with Exposure in Two Higher Institutions of Esan land, Edo State, Nigeria by F.A. Popoola, O.D. Fakeye, Q.B. Basiru, D.A. Adesina, M.A. Sulola

“…The total mean values for radiation dose estimation for Radium Equivalent Activity, Absorbed Dose, Excess Lifetime Cancer Risk, Outdoor and Indoor Annual Effective Dose Equivalent are 13.20 BqKg-1, 6.03 nGy/ℎ, 0.026, 7.40 µSτ/γ and 29.60 µSτ/γ respectively. …”
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Assessing the influence of matcha green tea extract on NF-κB/MAPK signaling pathway activation in rats: A study on irradiation-induced acute hepatic inflammatory response by Noha Sayed Hamed, Eithar K. El Adham, Amal I. Hassan

“…Background: Numerous forms of cancer are frequently treated with radiation therapy, which provides substantial benefits in tumor control. …”
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Evaluation of the Relationship Between Histopathological Tissue Diagnosis and Endometrial Thickness in Cases with Postmenopausal Bleeding by Mehmet Şükrü Budak, Mehmet Baki Şentürk, Sedat Akgöl, Mehmet Obut, Ali Emre Tahaoğlu, Cihan Toğrul, Ayhan Yıldırım

“…It appears that high parity ratios reduce the endometrium cancer risk. …”
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Any Long-term Effect of the Beirut Port Explosion on the Airborne Particulate Matter? by Yi-Bo Zhao, Nathalie Hayeck, Najat A. Saliba, Claudia Schreiner, Markus Zennegg, Fuze Jiang, Renato Figi, Davide Bleiner, Jing Wang

“…Protective measures must be taken to reduce the exposure risks by controlling the PM release from demolition and construction, traffic, and diesel generators. The cancer risk in Beirut based on PAHs measurements in 2021 was also estimated and discussed.…”
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