Emergency Medicine Palliative Care Access (EMPallA): protocol for a multicentre randomised controlled trial comparing the effectiveness of specialty outpatient versus nurse-led tel... by Jeanne Cho, Michael Hill, Corita R Grudzen, Deborah J Shim, Abigail M Schmucker, Keith S Goldfeld, Lauren Southerland, Jeffrey M Caterino, Marie-Carmelle Elie, Robert Swor, Susan E Cohen, Arum Kim, Joseph Lowy, Jennifer S Scherer, Nancy E Bael, Ellin Gafford, Joshua Lakin, Paige Barker, Angela Chmielewski, Jennifer Kapo, Audrey Tan, Rebecca Yamarik, Susan Salz, Stephen Ryan, Anne Kim, Isabel Castro, Amelia Hargrove, Laura Stuecher, Nora Daut, Juanita Booker-Vaughns, Garrett K Chan, J Nicholas Dionne-odom, Patrick Dunn, Robert Galvin, Ernest A Hopkins III, Margaret M Maguire, Neha Reddy Pidatala, Dawn Rosini, Sally Welsh, Karen Jubanyik, Ada L Rubin, Kei Ouchi, Rebecca Murray, Nicole Tang, Marie Bakitas, Abraham Brody, Caroline Blaum, Mara Flannery, Richard Tamirian, Pamela Marsack, Jennifer Bonito, Romilla Batra, Donna C Sadasivan, Eric David Isaacs, Constance L Kizzie-Gillett, William K Vaughan, Pluscedia G Williams, Angela Young-Brinn

“…Eligible patients: (1) have advanced cancer (metastatic solid tumour) or end-stage organ failure (New York Heart Association class III or IV heart failure, end-stage renal disease with glomerular filtration rate <15 mL/min/m2, or global initiative for chronic obstructive lung disease stage III, IV or oxygen-dependent chronic obstructive pulmonary disease); (2) speak English; (3) are scheduled for ED discharge or observation status; (4) reside locally; (5) have a working telephone and (6) are insured. …”
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AutoLDP: An accurate and efficient artificial intelligence-based tool for automatic labeling of digital pathology by Yingnan Zhao, Huifen Ye, Jing Yang, Su Yao, Maohua Lv, Zhihong Chen, Yunrui Ye, Qingru Hu, Cheng Lu, Zaiyi Liu, Ke Zhao, Zhihua Chen

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Hepatic Lamp2a deficiency promotes inflammation of murine autoimmune cholangitis via affecting bile acid metabolism by Qingling Fan, Guanya Guo, Yinan Hu, Yi Lu, Rui Su, Jiaqi Yang, Erzhuo Xia, Shuoyi Ma, Miao Zhang, Jingbo Wang, Ting Li, Ying Han

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Multiple large language models versus experienced physicians in diagnosing challenging cases with gastrointestinal symptoms by Xintian Yang, Tongxin Li, Han Wang, Rongchun Zhang, Zhi Ni, Na Liu, Huihong Zhai, Jianghai Zhao, Fandong Meng, Zhongyin Zhou, Shanhong Tang, Limei Wang, Xiangping Wang, Hui Luo, Gui Ren, Linhui Zhang, Xiaoyu Kang, Jun Wang, Ning Bo, Xiaoning Yang, Weijie Xue, Xiaoyin Zhang, Ning Chen, Rui Guo, Baiwen Li, Yajun Li, Yaling Liu, Tiantian Zhang, Shuhui Liang, Yong Lv, Yongzhan Nie, Daiming Fan, Lina Zhao, Yanglin Pan

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FusOn-pLM: a fusion oncoprotein-specific language model via adjusted rate masking by Sophia Vincoff, Shrey Goel, Kseniia Kholina, Rishab Pulugurta, Pranay Vure, Pranam Chatterjee

“…In total, FusOn-pLM provides biologically relevant representations for advancing therapeutic discovery in fusion-driven cancers.…”
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The RNA M5C methyltransferase NSUN2 promotes progression of hepatocellular carcinoma by enhancing PKM2-mediated glycolysis by Qin Qi, Rui Zhong, Yan Huang, Yong Tang, Xiao-wen Zhang, Chang Liu, Chun-fang Gao, Lin Zhou, Jian Yu, Lu-yi Wu

“…Abstract Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide. The 5-methylcytosine (m5C) RNA methyltransferase NSUN2 is involved in cell proliferation and metastasis and is upregulated in a variety of cancers. …”
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Citrus Flavonoid Effects on Obesity by Yu Wang, Laura E. Reuss

“…Obesity, a chronic disease that increases the risk for a myriad of diseases including diabetes, hypertension, cardiovascular diseases, as well as certain types of cancers, results from a persistent excess of energy intake versus energy expenditure and is characterized by an increase in both adipose cell size and number. …”
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Facts about Antioxidants by Kaitlin G. Clark, Wendy J. Dahl

“…Antioxidants also can help our immune system defend against bacteria, fungi, viruses, and some cancers. The body produces some of its own antioxidants, but eating a plant-based diet increases the level of antioxidants in our bodies. …”
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Morphological and endoscopic diagnostic criteria of serrated adenomas of the colon by A. M. Nechipay, M. V. Zobnina, L. M. Cherkasova, I. B. Perfilyev, V. A. Krivopuskov

“…At the present time hyperplastic polyps and other serrated neoplasms are considered to be precursor lesions for 15 to 20% of sporadic or asymptomatic colorectal cancers located mainly in proximal colon, that progress by specific serrated adenoma-related pathway. …”
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Advanced NGS analysis of cell-free tumor DNA supports clonal relation to primary high-grade B-cell lymphoma lesion and CNS relapse despite MRI negativity by Veronika Navrkalova, Andrea Mareckova, Jakub Porc, Samuel Hricko, Viera Hrabcakova, Jarmila Kissova, Sona Kundova, Marie Jarosova, Sarka Pospisilova, Jana Kotaskova, Andrea Janikova

“…Abstract High-grade B-cell lymphomas (HGBCLs) are aggressive blood cancers with a severe disease course, especially when the central nervous system (CNS) is involved. …”
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Artificial intelligence links CT images to pathologic features and survival outcomes of renal masses by Ying Xiong, Linpeng Yao, Jinglai Lin, Jiaxi Yao, Qi Bai, Yuan Huang, Xue Zhang, Risheng Huang, Run Wang, Kang Wang, Yu Qi, Pingyi Zhu, Haoran Wang, Li Liu, Jianjun Zhou, Jianming Guo, Feng Chen, Chenchen Dai, Shuo Wang

“…Improving the diagnosis of benign renal masses and distinguishing aggressive cancers from indolent ones is key to better treatment selection. …”
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EFFECT OF ORGANISATIONAL DYNAMICS ON ACCOUNTING PRACTICES OF LISTED DEPOSIT MONEY BANKS (DMBs) IN NIGERIA by Mubaraq Sanni

“… Accounting scandals and financial irregularities have always been conducted to achieve numerous objectives which however become cancerous issues truncating the survival of firms. …”
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Yield and horticultural performance of seed-oil pumpkin in south Florida by Geoffrey Meru, Yuqing Fu

“…Pumpkin seed is rich in oil (50% w/w), protein (35%), unsaturated fatty acids (86%) (Meru et al. 2018), and antioxidants that have many health benefits, including a reduced risk of certain cancers (Lelley et al. 2009; Nesaretnam et al. 2007; Stevenson et al. 2007), treatment of enlarged prostate, and  lowering cholesterol levels (Fruhwirth and Hermetter 2007; Thompson and Grundy 2005). …”
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LAMB1 downregulation suppresses glioma progression by inhibiting aerobic glycolysis through regulation of the NF-κB/HK2 axis by Zhenxiang Zhao, Haiying Liu, Yingzi Liu, Junpeng Wen, Jiangwei Yuan

“…Abstract Background Laminin subunit beta 1 (LAMB1) has regulatory functions on the proliferation, attachment, and migration of tumor cells, with increased levels linked to different cancers. Objective This study aims at investigating the effects and mechanisms of LAMB1 in glioma. …”
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Comprehensive analysis of differential mRNA and circRNA profiles in primary and metastatic pancreatic neuroendocrine tumors by Gang Li, Jing Zhang, Bentuo Zhang, Dan Wang, Zequn Wang, Yan Pan, Lijie Ma

“…We found that in pNET development and metastasis, 11 genes and 14 circRNAs were notably upregulated, while 25 genes and 35 circRNAs were significantly downregulated, compared to nearby non-cancerous tissue. Our analysis of differentially expressed RNA and circRNA genes revealed that tumor cell adhesion and integrin activation, regulated by genes like PIEZO1, IFT74, SKAP1, GPX1, F7, VTN, and OMG, are strongly linked to pNET metastasis. …”
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Double Stokes polarimetric microscopy for chiral fibrillar aggregates by Viktoras Mazeika, Kamdin Mirsanaye, Leonardo Uribe Castaño, Serguei Krouglov, Mehdi Alizadeh, Mykolas Maciulis, Lukas Kontenis, Vitalijus Karabanovas, Virginijus Barzda

“…DSP can be applied to investigate the origin of chiral complex-valued susceptibility of collagen, to study modifications of collagen in cancerous tissue, and to map ultrastructural parameters of large areas for whole-slide histopathology.…”
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Single-cell RNA sequencing reveals tumor heterogeneity in small cell neuroendocrine cervical carcinoma by Xuesong Xiang, Xiang Tao, Keqin Hua, Hua Jiang, Jingxin Ding

“…Here, we mapped the single-cell landscape of a total of six samples from matched SCNECC cancerous foci and normal adjacent cervical tissues. …”
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Comprehensive Overview - Outcomes and Challenges of Bariatric Surgery - Physical, Psychological and Nutritional Considerations by Katarzyna Doman, Dawid Komada, Kamil Hermanowicz, Daria Oleksy, Agnieszka Najdek, Urszula Kaczmarska, Aleksandra Woźniak, Marcin Mycyk, Julia Nowak, Michał Jakub Cioch

“… Obesity, defined by excessive and abnormal body fat accumulation, leads to various health conditions such as diabetes, cardiovascular diseases, and certain cancers, significantly affecting the health and increasing the risk of mortality. …”
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Ethnobotanical survey of medicinal and aromatic plants used by the population of Settat Province, Morocco by Manal Lahyaoui, Nadia Dakka, Naoual El Menyiy, Mansour Sobeh, Pakhrur Razi, Khang Wen Goh, Yaser Mohammed Al-Worafi, Muhammad Junaid Farrukh, Abdelhakim Bouyahya

“…The results highlighted the primary ailments treated with these plants, such as diabetes, gastrointestinal disorders, cardiovascular diseases, oral conditions, cancers, insomnia, and stress. Additionally, the study referenced traditional medicinal uses from various national studies and international scientific research that validated the therapeutic properties of each plant.…”
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Fucosylated haptoglobin promotes inflammation via Mincle in sepsis: an observational study by Taylor Roh, Sungeun Ju, So Young Park, Yeonghwan Ahn, Jiyun Chung, Miyako Nakano, Gyoungah Ryu, Young Jae Kim, Geumseo Kim, Hyewon Choi, Sung-Gwon Lee, In Soo Kim, Song-I Lee, Chaeuk Chung, Takashi Shimizu, Eiji Miyoshi, Sung-Soo Jung, Chungoo Park, Sho Yamasaki, Seung-Yeol Park, Eun-Kyeong Jo

“…Despite extensive research on Hp glycosylation as a glyco-biomarker for cancers, understanding glycosylated modifications of Hp in sepsis patients (SPs) remains limited. …”
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