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161
The Evaluation of Uterine Sarcomas: Tertiary Center Experience
Published 2024-08-01“…No statistically significant effect of adjuvant systemic chemotherapy, adjuvant radiotherapy, and combined treatments on median overall survival and median disease-free survival was detected (p>0.05). …”
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162
Recent research progress on metal ions and metal-based nanomaterials in tumor therapy
Published 2025-02-01“…Currently, the main methods of tumor treatment include surgery, radiotherapy, chemotherapy, etc., but these traditional treatment methods often have certain limitations. …”
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163
Factors associated with breast lymphedema after adjuvant radiation therapy in women undergoing breast conservation therapy
Published 2025-02-01“…Conclusion: Patients with larger breast volumes, Black patients, those receiving chemotherapy, and those who develop arm lymphedema or cellulitis may be at higher risk of BL after lumpectomy and RT, suggesting that patients with these risk features may benefit from complementary or alternative surgical approaches and heightened monitoring to avoid BL.…”
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164
An aggregation-induced emission-active lysosome hijacker: Sabotaging lysosomes to boost photodynamic therapy efficacy and conquer tumor therapeutic resistance
Published 2025-04-01“…This ultimately causes severe cell damage and restores the sensitivity of tumor cells to radiotherapy and chemotherapy. Thus, QM-DMAC serves as a highly efficient lysosome-targeting photosensitizer and an excellent therapeutic sensitizer. …”
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165
Do Pathologic Fractures in Long Bone Following Bony Malignancy Increase the Risk of Venous Thromboembolism? A Comparative Study
Published 2024-01-01“…This risk of developing DVT is increased much fold in the presence of metastasis, chemotherapy, radiotherapy, fracture fixation, and arthroplasty.…”
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166
Deep visual proteomics reveals DNA replication stress as a hallmark of signet ring cell carcinoma
Published 2025-02-01“…These findings suggest that pembrolizumab immunotherapy may be more effective than conventional chemotherapy for this patient. Our results provide novel insights into the proteomic landscape of SRCC, identify potential targets, and open up for personalized therapeutic strategies in managing SRCC.…”
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167
Computational Study of Trisindoline 5 Against Overexpressed EGFR Protein on Breast Cancer Stem Cell
Published 2025-01-01“…The current treatment to control the proliferation rate of breast cancer is still not optimal due to the presence of breast cancer stem cells (BCSCs) which are resistant to several chemotherapy agents. Epidermal Growth Factor Receptor (EGFR) may promote the survival of BCSCs. …”
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168
Biomarker panel for early detection of uterine cancer
Published 2024-10-01“…Various treatments modalities, including surgery, Chemotherapy, targeted therapies are examined. In conclusion, early detection through biomarkers like P53, K-RAS, HER2/neu, PTEN, Serum CA-125 holds great promise for early diagnosis and treatment advancements, and offering hope for improved outcomes and a better quality of life for patients in the future. …”
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169
CDCA7 enhances STAT3 transcriptional activity to regulate aerobic glycolysis and promote pancreatic cancer progression and gemcitabine resistance
Published 2025-02-01“…CDCA7 overexpression promoted PC cell proliferation, migration, and invasion, and increased resistance to the chemotherapy drug gemcitabine, possibly through enhanced aerobic glycolysis. …”
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170
Pattern of Orbito-ocular Tumours in Nigeria: a systematic review
Published 2025-02-01“…The most common malignant tumours were retinoblastoma (in children) and conjunctival squamous cell carcinoma (in adults) while squamous papilloma was the most common benign tumour. Chemotherapy with or without surgeries was the most common intervention with varied treatment outcomes due to the nature and stage of tumour, adherence to treatment, and follow-up plan.…”
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171
Genetic advancements in breast cancer treatment: a review
Published 2025-02-01“…Traditional treatments, including surgery, chemotherapy, and radiation, face limitations such as drug resistance, metastasis, and severe side effects. …”
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172
Rare Encounter Behind the Ear: Unveiling Kimura Disease in the Postaural Region
Published 2024-11-01“…Treatment options encompass systemic steroids, antihistamines, immunosuppressants, chemotherapy, radiotherapy, and surgical excision. Despite interventions, the disease often locally recurs. …”
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173
A review of leishmaniasis: current knowledge and future directions of heterocyclic molecules
Published 2024-09-01“…The review also explores various therapies for leishmanial diseases, from chemotherapy to immunotherapy, and discusses their advantages and limitations. …”
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174
Cuproptosis-related lncRNAs and genes: Potential markers for glioblastoma prognosis and treatment.
Published 2025-01-01“…Cuproptosis, caused by intracellular copper, is a novel RCD process that affects chemotherapy efficacy and glioma progression; however, the precise function of cuproptosis-related lncRNAs (CRLs) and cuproptosis-related genes (CRGs) in GBM remains uncertain. …”
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175
Advances in preclinical and clinical studies of oncolytic virus combination therapy
Published 2025-02-01“…This paper summarizes the tumor-killing mechanisms of oncolytic viruses, explores their integration with radiotherapy, chemotherapy, immune checkpoint inhibitors, CAR-T, and CAR-NK therapies, and provides an overview of related clinical trials. …”
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176
Long-term Outcome of Vascularized Fibular Bone Graft Reconstruction for Upper Limb Osteosarcoma: A Case Report
Published 2024-06-01“…Materials and methods: This is a case report of a 34-year-old female who underwent left proximal humerus osteosarcoma wide excision and reconstruction with free vascularized fibula graft and chemotherapy 12 years back. During these 12 years, the patient had gradual improvement in her movements in her left upper limb and overall outcome. …”
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177
Clinicopathological features and evaluation of microsatellite stability of colorectal carcinoma with cribriform comedo pattern
Published 2024-04-01“…Because this feature is important for planning adjuvant chemotherapy, it may be useful to identify cases, particularly with a cribriform comedo pattern >90%. …”
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178
Anterior clinoid process metastasis with sudden loss of vision: role of emergency optic nerve decompression
Published 2025-02-01“…Case presentation We report the case of a 41-year-old male patient with a diagnosis of radius leiomyosarcoma, who underwent surgery in 2014, with bone and lung metastases, who had been treated with chemotherapy and appeared to have the disease controlled at his last follow-up. 6 years later, he developed a one month history of progressive unilateral loss of visual acuity and visual field defect (initially quadrantanopia that progressed to nasal hemianopia). …”
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179
Multiple machine learning-based integrations of multi-omics data to identify molecular subtypes and construct a prognostic model for HNSCC
Published 2025-02-01“…High-risk patients were more sensitive to radiotherapy and chemotherapy (e.g., Cisplatin, 5-Fluorouracil), while low-risk patients responded better to immunotherapy and targeted therapies. …”
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180
Green Strategy–Based Synthesis of Silver Nanoparticles for Antibacterial Applications
Published 2021“…Antibiotics have been the nucleus of chemotherapy since their discovery and introduction into the healthcare system in the 1940s. …”
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