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1701
Predictors of infliximab efficacy in patients with severe attack of ulcerative colitis
Published 2013-10-01“…High cost of such treatment and risk of adverse events related to it requires definition of strict indications for application of this drug. It was necessary to detect factors due to which at early stage of biological therapy it is possible to decide whether infliximab will allow to achieve long-term clinical remission, and also to avoid operative treatment.Material and methods. …”
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1702
Immunogenicity and safety of a live attenuated varicella vaccine in healthy subjects aged between 13 to 55 years: a double-blind, randomized, active-controlled phase iii clinical t...
Published 2025-12-01“…Varicella-zoster virus (VZV) antibody was detected before vaccination and 42 days after two doses of vaccination.Results The lower limits of the 95% CI for the differences in seroconversion rates and geometric mean titer (GMT) ratios between the two groups were greater than their respective pre-set non-inferiority margins. …”
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1703
The validity of the renal Doppler resistivity index in renal allograft infections
Published 2025-12-01“…There was a statistically significant difference in RRI in those with allograft infections, with the ROC curve for detection of infection utilizing RRI demonstrated an Area Under Curve 0.634 (p-value 0.015; cutoff value: 0.765; CI:0.527–0.742), with a specificity of 64.4% and a sensitivity of 68.8%.Conclusion Normal renal graft arterial resistivity index values, despite a renal allograft dysfunction, may be indicative of allograft infection, guiding clinicians’ decisions regarding kidney biopsy and facilitating further biopsy interpretations.…”
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1704
Two Approaches to Cognitive Evaluation: Assessing the Strengths and Limitations of GPCOG and ACE-III
Published 2025-02-01“…Combined, they enhance early detection and management of cognitive disorders. …”
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1705
The Conscious Side of ‘Subliminal’ Linguistic Priming: A Systematic Review With Meta-Analysis and Reliability Analysis of Visibility Measures
Published 2025-01-01“…One strategy to establish this automaticity involves detecting significant syntactic priming effects in tasks that limit conscious awareness of the stimuli. …”
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1706
Acid sphingomyelinase modulates anxiety-like behavior likely through toll-like receptor signaling pathway
Published 2025-02-01“…Transcriptional profiling combined with bioinformatics analysis revealed the upregulation of Toll-like receptor signaling pathway related gene including Tlr1/2, Ccl3, Ccl4, Ccl5 and Cd86 in Asm KO mice, which was further confirmed by the detection of activated microglia and astrocytes through iba-1 and GFAP immunohistochemical staining. …”
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1707
Biochemical Pattern of Methylmalonyl-CoA Epimerase Deficiency Identified in Newborn Screening: A Case Report
Published 2024-07-01“…Here, we report for the first time the biochemical description of a case detected by NBS. The NBS results showed increased levels of propionylcarnitine (C3) and 2-methylcitric acid (MCA), while methylmalonic acid (MMA) and homocysteine (Hcy) were within the reference limits. …”
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1708
Non-target effects of ten essential oils on the egg parasitoid Trichogramma evanescens
Published 2023-01-01“…Most EOs also affect parasitoid behavior: (i) Basil, Coriander, Oregano, Peppermint, Mugwort and Thyme EOs are highly repellent for naive female parasitoids; (ii) Anise and Fennel EOs can have repellent or attractive effects depending on strains; and (iii) Sweet orange, Oregano and Rosemary EOs have no detectable impact on orientation behavior. This study shows that EOs fumigation have non-target effects on egg parasitoids. …”
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1709
A 20 m spatial resolution peatland extent map of Alaska
Published 2025-02-01“…Ground-data were used to train machine learning classifiers to detect peatlands using a fusion of Sentinel-1 (Dual-polarized Synthetic Aperture Radar), Sentinel-2 (Multi-Spectral Imager), and derivatives from the Arctic Digital Elevation Model (ArcticDEM), that were spatially constrained by a peatland suitability model. …”
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1710
Natural selection and adaptive traits in the Maniq, a nomadic hunter-gatherer society from Mainland Southeast Asia
Published 2025-02-01“…Balancing selection was primarily detected in immune-related genes, particularly within the HLA region, underscoring the critical role of genetic diversity in surviving pathogen-rich environments. …”
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1711
Diversity of beetles (Arthropoda, Insecta, Coleoptera) associated with coniferous forests in Honduras
Published 2025-02-01“…Within I. apache, evidence of intraspecific genetic diversity was observed, although no population structure was detected. While this research provides an updated inventory of beetle species associated with Honduran coniferous forests, further taxonomic surveys and ecological studies are essential to better understand the spread and impact of bark beetles in pine ecosystems.…”
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1712
Looking outside the box with a pathology aware AI approach for analyzing OCT retinal images in Stargardt disease
Published 2025-02-01“…In severely affected regions, identified by a box detection model, the total retina is segmented as a single layer to avoid errors. …”
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1713
Genomic epidemiology and phenotypic characterization of Staphylococcus aureus isolated from atopic dermatitis patients in South China
Published 2025-02-01“…Genes esaC, esxB, and sea were only detected in ST7, potentially contributing to its prevalence in AD. …”
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1714
Structure and function of a β-1,2-galactosidase from Bacteroides xylanisolvens, an intestinal bacterium
Published 2025-01-01“…However, when α-d-galactosyl fluoride (α-GalF) as a donor substrate and galactose or d-fucose as an acceptor substrate are incubated with a nucleophile mutant, reaction products are detected. The galactobiose produced from the α-GalF and galactose is identified as β-1,2-galactobiose using NMR. …”
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1715
Multigenerational effects of cultivating transgenic maize straw on earthworms: A combined laboratory and field experiment
Published 2025-02-01“…No significant differences in the survival, body weight, cocoon production, or hatching of earthworms fed GM or non-GM DBN318 maize were detected after three consecutive generations in a laboratory test. …”
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1716
Antegrade Endobiliary Forceps Biopsy Improves Diagnosis of Klatskin Tumor Compared to Brush Biopsy
Published 2022-08-01“…Malignant lesions of the biliary tract were detected by forceps technique in 79.0 %, brush biopsy in 66.7 % (p >0,05). …”
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1717
The prevalence, clinical features, and long-term outcome of patients with primary Sjögren’s syndrome with renal involvement
Published 2025-02-01“…Therefore, screening for renal involvement is important for preserving renal function and early detection of LPD.…”
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1718
Leveraging transformer models to predict cognitive impairment: accuracy, efficiency, and interpretability
Published 2025-02-01“…Its capacity to process both continuous and categorical data and its interpretability through attention mechanisms make it a promising tool for early detection of neurodegenerative diseases, potentially improving clinical decision-making and interventions.…”
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1719
A case report of confirmed difficult pulmonary tuberculosis based on the hybrid capture-based tNGS method
Published 2025-02-01“…Conclusion The hc-tNGS has significant value in diagnosing pulmonary tuberculosis, especially in cases that are difficult to detect with other methods. In the future, this could gradually become a routine diagnostic method for pulmonary tuberculosis, enhancing the accuracy of early diagnosis.…”
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1720
Overexpression of NtCET4 gene in tobacco promoted vegetative bud activity and delayed flowering
Published 2025-01-01“…NtCET4 expression in transgenic plants was increased from seedling to mature, and higher expression was detected before flowering relative to after flowering. …”
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