Predictors of infliximab efficacy in patients with severe attack of ulcerative colitis by A. O. Golovenko, I. L. Khalif, O. V. Golovenko, V. V. Veselov

“…High cost of such treatment and risk of adverse events related to it requires definition of strict indications for application of this drug. It was necessary to detect factors due to which at early stage of biological therapy it is possible to decide whether infliximab will allow to achieve long-term clinical remission, and also to avoid operative treatment.Material and methods. …”
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Immunogenicity and safety of a live attenuated varicella vaccine in healthy subjects aged between 13 to 55 years: a double-blind, randomized, active-controlled phase iii clinical t... by Yang Zhang, Shiyuan Wang, Guifan Li, Jinhui Shi, Xianyun Chang, Hao Zhang, Fengcai Zhu, Jingxin Li, Hongxing Pan, Jinfang Sun

“…Varicella-zoster virus (VZV) antibody was detected before vaccination and 42 days after two doses of vaccination.Results The lower limits of the 95% CI for the differences in seroconversion rates and geometric mean titer (GMT) ratios between the two groups were greater than their respective pre-set non-inferiority margins. …”
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The validity of the renal Doppler resistivity index in renal allograft infections by Moataz Fatthy, Karim M. Soliman, Éva Csongrádi, Abd El Rahman Marzouk, Ahmed Fathy, Ahmed Fayed

“…There was a statistically significant difference in RRI in those with allograft infections, with the ROC curve for detection of infection utilizing RRI demonstrated an Area Under Curve 0.634 (p-value 0.015; cutoff value: 0.765; CI:0.527–0.742), with a specificity of 64.4% and a sensitivity of 68.8%.Conclusion Normal renal graft arterial resistivity index values, despite a renal allograft dysfunction, may be indicative of allograft infection, guiding clinicians’ decisions regarding kidney biopsy and facilitating further biopsy interpretations.…”
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Two Approaches to Cognitive Evaluation: Assessing the Strengths and Limitations of GPCOG and ACE-III by Magdalena Mąka, Dominik Sikora, Piotr Oleksy, Adam Zając, Karol Zieliński, Łukasz Papież, Ewa Góralczyk, Jakub Kamiński, Bartosz Buczkowski, Dagmara Wochnik

“…Combined, they enhance early detection and management of cognitive disorders. …”
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The Conscious Side of ‘Subliminal’ Linguistic Priming: A Systematic Review With Meta-Analysis and Reliability Analysis of Visibility Measures by David Hernández-Gutiérrez, Miguel A. Sorrel, David R. Shanks, Miguel A. Vadillo

“…One strategy to establish this automaticity involves detecting significant syntactic priming effects in tasks that limit conscious awareness of the stimuli. …”
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Acid sphingomyelinase modulates anxiety-like behavior likely through toll-like receptor signaling pathway by Huiqi Yuan, Yanan Xu, Hailun Jiang, Meizhu Jiang, Luofei Zhang, Shifeng Wei, Cao Li, Zhigang Zhao

“…Transcriptional profiling combined with bioinformatics analysis revealed the upregulation of Toll-like receptor signaling pathway related gene including Tlr1/2, Ccl3, Ccl4, Ccl5 and Cd86 in Asm KO mice, which was further confirmed by the detection of activated microglia and astrocytes through iba-1 and GFAP immunohistochemical staining. …”
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Biochemical Pattern of Methylmalonyl-CoA Epimerase Deficiency Identified in Newborn Screening: A Case Report by Evelina Maines, Roberto Franceschi, Francesca Rivieri, Giovanni Piccoli, Björn Schulte, Jessica Hoffmann, Andrea Bordugo, Giulia Rodella, Francesca Teofoli, Monica Vincenzi, Massimo Soffiati, Marta Camilot

“…Here, we report for the first time the biochemical description of a case detected by NBS. The NBS results showed increased levels of propionylcarnitine (C3) and 2-methylcitric acid (MCA), while methylmalonic acid (MMA) and homocysteine (Hcy) were within the reference limits. …”
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Non-target effects of ten essential oils on the egg parasitoid Trichogramma evanescens by van Oudenhove, Louise, Cazier, Aurélie, Fillaud, Marine, Lavoir, Anne-Violette, Fatnassi, Hicham, Perez, Guy, Calcagno, Vincent

“…Most EOs also affect parasitoid behavior: (i) Basil, Coriander, Oregano, Peppermint, Mugwort and Thyme EOs are highly repellent for naive female parasitoids; (ii) Anise and Fennel EOs can have repellent or attractive effects depending on strains; and (iii) Sweet orange, Oregano and Rosemary EOs have no detectable impact on orientation behavior. This study shows that EOs fumigation have non-target effects on egg parasitoids. …”
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A 20 m spatial resolution peatland extent map of Alaska by Mark J. Lara, Roger Michaelides, Duncan Anderson, Wenqu Chen, Emma C. Hall, Caroline Ludden, Aiden I. G. Schore, Umakant Mishra, Sarah N. Scott

“…Ground-data were used to train machine learning classifiers to detect peatlands using a fusion of Sentinel-1 (Dual-polarized Synthetic Aperture Radar), Sentinel-2 (Multi-Spectral Imager), and derivatives from the Arctic Digital Elevation Model (ArcticDEM), that were spatially constrained by a peatland suitability model. …”
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Natural selection and adaptive traits in the Maniq, a nomadic hunter-gatherer society from Mainland Southeast Asia by Tobias Herzog, Maximilian Larena, Wibhu Kutanan, Helmut Lukas, Martin Fieder, Helmut Schaschl

“…Balancing selection was primarily detected in immune-related genes, particularly within the HLA region, underscoring the critical role of genetic diversity in surviving pathogen-rich environments. …”
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Diversity of beetles (Arthropoda, Insecta, Coleoptera) associated with coniferous forests in Honduras by Mauricio Hernández, Mauricio Michel, Joel García, Geisy Dueñas, Marcela Moncada, Kevin Amaya, Yensi Yánez, Alejandra Pinto, Gabriela Matamoros, Alejandro Zamora, Gustavo Fontecha

“…Within I. apache, evidence of intraspecific genetic diversity was observed, although no population structure was detected. While this research provides an updated inventory of beetle species associated with Honduran coniferous forests, further taxonomic surveys and ecological studies are essential to better understand the spread and impact of bark beetles in pine ecosystems.…”
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Looking outside the box with a pathology aware AI approach for analyzing OCT retinal images in Stargardt disease by Parisa Khateri, Tiana Koottungal, Damon Wong, Rupert W. Strauss, Lucas Janeschitz-Kriegl, Maximilian Pfau, Leopold Schmetterer, Hendrik P. N. Scholl

“…In severely affected regions, identified by a box detection model, the total retina is segmented as a single layer to avoid errors. …”
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Genomic epidemiology and phenotypic characterization of Staphylococcus aureus isolated from atopic dermatitis patients in South China by Chao Yang, Xiaowei Chen, Min Li, Wenchang Yuan, Shunguang Li, Dexing Han, Junhui Feng, Haimin Luo, Minling Zheng, Jiaqi Liang, Cha Chen, Pinghua Qu, Song Li

“…Genes esaC, esxB, and sea were only detected in ST7, potentially contributing to its prevalence in AD. …”
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Structure and function of a β-1,2-galactosidase from Bacteroides xylanisolvens, an intestinal bacterium by Yutaka Nakazawa, Masumi Kageyama, Tomohiko Matsuzawa, Ziqin Liang, Kaito Kobayashi, Hisaka Shimizu, Kazuki Maeda, Miho Masuhiro, Sei Motouchi, Saika Kumano, Nobukiyo Tanaka, Kouji Kuramochi, Hiroyuki Nakai, Hayao Taguchi, Masahiro Nakajima

“…However, when α-d-galactosyl fluoride (α-GalF) as a donor substrate and galactose or d-fucose as an acceptor substrate are incubated with a nucleophile mutant, reaction products are detected. The galactobiose produced from the α-GalF and galactose is identified as β-1,2-galactobiose using NMR. …”
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Multigenerational effects of cultivating transgenic maize straw on earthworms: A combined laboratory and field experiment by Li Zhang, Wenjing Shen, Zhixiang Fang, Laipan Liu, Ruizong Jia, Jingang Liang, Biao Liu

“…No significant differences in the survival, body weight, cocoon production, or hatching of earthworms fed GM or non-GM DBN318 maize were detected after three consecutive generations in a laboratory test. …”
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Antegrade Endobiliary Forceps Biopsy Improves Diagnosis of Klatskin Tumor Compared to Brush Biopsy by A. V. Kozlov, P. G. Tarazov, A. A. Polikarpov, A. V. Moiseenko, A. I. Urbansky, M. V. Yutkin, G. M. Yakshieva, D. A. Granov

“…Malignant lesions of the biliary tract were detected by forceps technique in 79.0 %, brush biopsy in 66.7 % (p >0,05). …”
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The prevalence, clinical features, and long-term outcome of patients with primary Sjögren’s syndrome with renal involvement by Howook Jeon, Youngjae Park, Jennifer Jooha Lee, Yoo-Seok Suh, Seung-Ki Kwok, Sung-Hwan Park, Wan-Uk Kim, Jung Hee Koh

“…Therefore, screening for renal involvement is important for preserving renal function and early detection of LPD.…”
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Leveraging transformer models to predict cognitive impairment: accuracy, efficiency, and interpretability by Kai Ma, Junzhi Zhang, Xinhang Huang, Mengyang Wang

“…Its capacity to process both continuous and categorical data and its interpretability through attention mechanisms make it a promising tool for early detection of neurodegenerative diseases, potentially improving clinical decision-making and interventions.…”
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A case report of confirmed difficult pulmonary tuberculosis based on the hybrid capture-based tNGS method by Weiqian Chen, Huimin Chen, Ze Liu, Xinle Chi, Yaomeng Chen, Huan Ye, Wenjie Huang, Chenlei Cao, Wei Weng

“…Conclusion The hc-tNGS has significant value in diagnosing pulmonary tuberculosis, especially in cases that are difficult to detect with other methods. In the future, this could gradually become a routine diagnostic method for pulmonary tuberculosis, enhancing the accuracy of early diagnosis.…”
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Overexpression of NtCET4 gene in tobacco promoted vegetative bud activity and delayed flowering by LONG Junlan, LUO Rui, LUO Xu, ZHANG Lan

“…NtCET4 expression in transgenic plants was increased from seedling to mature, and higher expression was detected before flowering relative to after flowering. …”
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