A biallelically active embryonic enhancer dictates GNAS imprinting through allele-specific conformations by Yorihiro Iwasaki, Monica Reyes, Harald Jüppner, Murat Bastepe

“…Therefore, a biallelically active embryonic enhancer dictates GNAS imprinting via different chromatin conformations, underlying the allele-specific pathogenicity of STX16-ICR microdeletions.…”
Get full text

Kaposi's sarcoma-associated herpesvirus (KSHV) gB dictates a low-pH endocytotic entry pathway as revealed by a dual-fluorescent virus system and a rhesus monkey rhadinovirus expressing KSHV gB. by Shanchuan Liu, Sarah Schlagowski, Anna K Großkopf, Natalia Khizanishvili, Xiaoliang Yang, Scott W Wong, Elina M Guzmán, Marija Backovic, Stefano Scribano, Arne Cordsmeier, Armin Ensser, Alexander S Hahn

Get full text

Considerations for Selecting a Bull by Martha Thomas, Matt Hersom

“…AN218, a 3-page fact sheet by Martha Thomas and Matt Hersom, lists factors to consider for selecting a bull, one of the largest decisions dictating carcass merit for the subsequent calves. …”
Get full text

Language assessment in primary progressive aphasia: Which components should be tested? by Andressa Aguiar da Silva, Marcela Lima Silagi, Karin Zazo Ortiz

“…<h4>Results</h4>A statistically significant performance difference was found between the PPAG and CG on the following tasks: structured interview, oral comprehension of phrases, oral narrative discourse, written comprehension of phrases, written dictation, sentence repetition, semantic verbal fluency, oral naming of nouns and verbs, object manipulation, phonological verbal fluency, body part recognition and left-right orientation, written naming of nouns, oral text comprehension, number dictation, written narrative discourse, written text comprehension and numerical calculations (mental and written).…”
Get full text

2019–2020 Florida Citrus Production Guide: Citrus Cold Protection by Tripti Vashisth, W. Chris Oswalt

“…Since the introduction of citrus by the Spanish in the 1500s, freezing temperatures have dictated where the citrus production areas in Florida are located. …”
Get full text

Nursery Crop Selection and Market Niches by Gary W. Knox, Matthew Chappell

“…This 5-page fact sheet describes several important factors that must be considered in order to properly assess which ornamental crops should be grown and which market niches exist that may dictate crop selection. Written by Gary Knox and Matthew Chappell and published by the UF Department of Environmental Horticulture, November 2011. …”
Get full text

Increase in treatment compliance reveals new options of treatment of gastroesophageal reflux disease by Yu. V. Yevsyutina, A. S. Trukhmanov

“…The wide prevalence of GERD dictates necessity of search of new effective agents. …”
Get full text

Iron-catalysed stereoselective NH transfer enables dynamic kinetic resolution of sulfoxides by Fang-Xu Fan, Hui Xu, Shi-Xiong Tang, Yanfeng Dang, Fei Wang

“…In addition, the stereoselectivity is primarily dictated by the difference in dispersion interactions of the transition states.…”
Get full text

Breaking the wire: the impact of critical length on melting pathways in silver nanowires by K M Ridings, E E L Vaka’uta, S M Croot

“…We explore the melting mechanisms of silver nanowires through molecular dynamics simulations and theoretical modelling, where we observe that two distinct mechanisms or pathways emerge that dictate how the solid-liquid interface melts during the phase transition. …”
Get full text

In-silico platform for the multifunctional design of 3D printed conductive components by Javier Crespo-Miguel, Sergio Lucarini, Sara Garzon-Hernandez, Angel Arias, Emilio Martínez-Pañeda, Daniel Garcia-Gonzalez

“…The former determines the multifunctional nature of the composite, whereas the latter dictates the mesostructural characteristics such as filament adhesion and void distribution. …”
Get full text

Christianity and medical science: A historical quest for remedy in time of epidemics by V.U. Iheanacho

“…For its part, reason dictates what needs to be done in terms of practical and necessary measures to alleviate pain and suffering while waiting for divine intervention. …”
Get full text

Satisfaction by the certain subjective success in career by Janjić Ivana, Ilić Đurđijana

“…For modern business, characterized by strong competition and constant change, the labor market dictates the requirements of developing personal abilities. …”
Get full text

Ischemic heart disease and reflux-esophagitis: complexities of the differential diagnosis and treatment. by Yu. N. Belenkov, Ye. V. Privalova, A. O. Yusupova, M. V. Kozhevnikova

“…Combination of diseases requires long treatment, dictates necessity of choice of the safe agent, having no negative effect on the course of IHD.Conclusion. …”
Get full text

Adjuvants for peptide-based cancer vaccines by Willem W Overwijk, Hiep Khong

“…As vaccine adjuvants dictate the type and magnitude of the T cell response after vaccination, it is critical to understand how they work to design safe, but also effective, cancer vaccines for clinical use. …”
Get full text

COVID-19 Pandemic and Irritable Bowel Syndrome — is there a Relationship? by V. A. Akhmedov

“…It was shown that during the pandemic, more than 90 % of the interviewed patients with IBS had an exacerbation of IBS with an increase in symptoms such as bloating and cramps, and 75 % of them said that the exacerbation of symptoms was reflected in the activity of patients in everyday life. These factors dictate the need for an integrated approach in the management of such a group of patients with the use of modern multi-target drugs that affect the pathogenetic factors in the formation of functional gastrointestinal diseases, one of which is the Kolofort drug due to the triple multi-target mechanism of action on the pathogenesis of functional gastrointestinal diseases.…”
Get full text

Targeting adipocyte ESRRA promotes osteogenesis and vascular formation in adipocyte-rich bone marrow by Tongling Huang, Zhaocheng Lu, Zihui Wang, Lixin Cheng, Lu Gao, Jun Gao, Ning Zhang, Chang-An Geng, Xiaoli Zhao, Huaiyu Wang, Chi-Wai Wong, Kelvin W. K. Yeung, Haobo Pan, William Weijia Lu, Min Guan

“…ESRRA abrogation results in enhanced SPP1 and decreased leptin secretion from both visceral adipocytes and BMAds, concertedly dictating bone marrow stromal stem cell fate commitment and restoring type H vessel formation, constituting a feed-forward loop for bone formation. …”
Get full text

R-loops acted on by RNase H1 influence DNA replication timing and genome stability in Leishmania by Jeziel D. Damasceno, Emma M. Briggs, Marija Krasilnikova, Catarina A. Marques, Craig Lapsley, Richard McCulloch

“…This work provides a link between R-loop homeostasis and DNA replication timing in a eukaryotic parasite and demonstrates that orchestration of DNA replication dictates levels of genome plasticity in Leishmania.…”
Get full text

Information and Communication Technology Adoption and the Growth of Small Medium Enterprises in Uganda: Empirical Evidence from Kampala City Council Authority by Eton, Marus, Constant, Okello Obura, Fabian, Mwosi, Benard, Patrick Ogwel, Mary, Ejang, Francis, Ongia

“…Training institutions should strengthen the ICT training programs by aligning them to the required job demands as dictated in the field of business. Government should also promote the application and adoption of ICT e-business by slashing the exorbitant taxes charged on the use of these products. …”
Get full text