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121
Current Trends in Treatment for Acid-Dependent Diseases: Clinical Efficacy and Safety of Rabeprazole
Published 2021-12-01“…A lower rabeprazole metabolic dependence on cytochrome P-450 enzyme system renders its antisecretory effect predictable and reduces the risk of interactions with other drugs metabolised through this system. …”
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122
Viral hepatitis B epidemiology in Sakha republic (Yakutia)
Published 2015-09-01“…Data of the Russian Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing (Rospotrebnadzor) for Sakha republic (report form #1) and results of enzyme-linked immunoassay (EIA) for viral hepatitis markers (HBsAg, a-HBcor IgG, a-HDV, a-HCV) in population of 17 areas of republic were utilized.Results. …”
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123
The Impact of COVID-19 on Gametes and Endometrium: A Narrative Review
Published 2023-03-01“…Whereas the available data suggest that SARS-CoV-2 interferes with various types of molecular pathways in the oocyte, spermatozoa, and endometrium, the lack of co-expression in angiotensin-converting enzyme 2 and transmembrane protease serine 2 in those cell lines theoretically avoid concerns by patients and reproductive endocrinologists. …”
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124
Comparison of Vitamin-D binding protein levels in gingival crevicular fluid of pre- and postmenopausal women with and without chronic periodontitis: A clinico-biochemical study
Published 2023-07-01“…GCF DBP levels were evaluated using an enzyme-linked immunosorbent assay kit. Results: There was a significant correlation between menopausal status and periodontal status in relation to GCF DBP levels (P = 0.000). …”
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125
Enzymatic functionalization of bacterial nanocellulose: current approaches and future prospects
Published 2025-02-01“…An alternative to these procedures is the highly specific enzymatic modification of bacterial nanocellulose, which perfectly fits into the assumptions of green technologies, making the process eco-friendly and not limiting any outlooks for further usage of the obtained biocomposites. The employment of enzymes for the targeted alteration of this material’s properties is based on either a direct method, such as controlled hydrolysis and nanofication [i.e., synthesis of different morphological forms of bacterial cellulose (e.g., rod-shaped nanocrystals)] using cellulases, and/or attachment of reactive functional groups into the polymer structure via oxidation (e.g., utilizing a laccase/TEMPO catalytic system or lytic polysaccharide monooxygenases) and esterification catalyzed by lipases; or an indirect procedure involving the application of bacterial nanocellulose as a matrix for enzyme immobilization (e.g., laccase, glucose oxidase, horseradish peroxidase, lysozyme, bromelain, lipase, papain), thus creating a specific catalytic system. …”
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126
Investigation into the sero-molecular prevalence of Brucella melitensis in small ruminants in districts Mohmand and Charsadda Khyber Pakhtunkhwa Pakistan.
Published 2025-01-01“…A total of 400 blood samples were collected from sheep and goats (n = 200 from each species) and analyzed by Rose Bengal precipitation test (RBPT), the indirect enzyme-linked immunosorbent assay (i-ELISA) and polymerase chain reaction (PCR). …”
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127
Recent advances in small molecule LpxC inhibitors against gram-negative bacteria (2014–2024)
Published 2025-02-01“…Uridine diphosphate-3-O-(hydroxymyristoyl)-N-acetylglucosamine deacetylase (LpxC) is a metalloenzyme cofactored with zinc ions, which is a key enzyme in the synthesis of outer membrane lipid A in Gram negative bacteria. …”
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128
Assessment of Brush Biopsy Findings and Salivary LDH Levels in Oral Mucosal Lesions of Tobacco Users
Published 2023-04-01“…Introduction: The oral brush cytology is an alternative method developed to improve the efficacy of conventional cytology in oral potentially malignant disorder (OPMD), and salivary lactate dehydrogenase (LDH) which is a cytoplasmic enzyme has been widely used as a marker for diagnosing various diseases. …”
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129
Nanozyme-based aptasensors for the detection of tumor biomarkers
Published 2025-02-01“…Nanozymes are nanomaterials that possess enzyme-like properties, demonstrating substantial potential for enhancing the sensing capabilities of biosensors. …”
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130
Combined Effects of Humic Acid-Modified Magnetic Biochar and AMF on the Properties of Saline-Alkali Soil and Photosynthetic Parameters of Muskmelon
Published 2024-12-01“…Moreover, by conducting pot experiments, the influence of individual fungi, individual biochar, and combined biochar-fungi (AMF+10%B, AMF+20%B) on the physicochemical properties, and enzyme activities of saline soil and alkaline soil, and the photosynthetic parameters of muskmelon were studied. …”
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131
New advances in biological preservation technology for aquatic products
Published 2025-02-01“…Moreover, the preservation mechanisms of bio-preservatives, including antioxidant activity, inhibition of spoilage bacteria and enzyme activity, and the formation of protective films are reviewed. …”
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132
Exogenously applied ABA alleviates dysplasia of maize (Zea mays L.) ear under drought stress by altering photosynthesis and sucrose transport
Published 2025-12-01“…Exogenous ABA inhibited bald tip and the decline of maize plant biomass, and increased the number and weight of grains per ear at harvest under drought stress by regulating photosynthetic pigment content (Chla, Chlb, Car), gas exchange parameters (Pn, Tr, gs, Ci, Ls), Chla fluorescence parameters (Fv/Fm, ФPSII, ETR, qP, NPQ), chloroplast structure and function, photosynthetic enzyme activity, and the transcription level of genes coding SUTs (ZmSUT1, ZmSUT2, ZmSUT4, ZmSUT6). …”
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133
Changes in the Intestinal Microbiota in Patients with Chronic Pancreatitis: Systematizing Literature Data
Published 2022-12-01“…The severe CP is associated with impaired synthesis of antimicrobial peptides, bicarbonates, and digestive enzymes by the pancreas, which is a risk factor for dysbiotic changes in the intestinal microbiota, consisting in the development of small intestinal bacterial overgrowth (SIBO) and gut dysbiosis. …”
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134
Probing the role of Coniferin and Tetrahydrocurcumin from Traditional Chinese medicine against PSAT1 in early-stage ovarian cancer: An in silico study.
Published 2025-01-01“…In this work, we used computational approaches to find putative Traditional Chinese Medicine (TCM) inhibitors that target Phosphoserine Aminotransferase 1 (PSAT1), a crucial enzyme linked to the development of early-stage ovarian cancer. …”
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135
Glucoraphanin conversion into sulforaphane and related compounds by gut microbiota
Published 2025-02-01“…Sulforaphane is formed by the hydrolysis of glucoraphanin by a plant enzyme called myrosinase, which is inactivated in the stomach of mammals. …”
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136
Thymol maintains peppers quality by regulating antioxidant capacity, cell wall metabolism and membrane lipid metabolism
Published 2025-01-01“…Additionally, thymol application inhibited the hydrolysis of pepper cell wall components and decreased the activities of enzymes related to cell wall and membrane lipid metabolism. …”
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137
AI-driven prediction of drug activity against Toxoplasma gondii: Data augmentation and deep neural networks for limited datasets
Published 2025-06-01“…Toxoplasmosis, caused by Toxoplasma gondii (T. gondii), is a serious global health concern, particularly in immunocompromised individuals. Inhibiting the enzyme TgDHFR is a promising strategy for developing treatments. …”
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138
Markers of chronic hepatitis B at patients with HIV-infection and treatment approaches
Published 2010-11-01“…All blood samples were investigated for the presence of НBV, HDV, HCV, HAV-virus markers in serum by enzyme-linked immunoassay and for the presence of RNA HIV, RNA HCV and DNA HBV by polymerase chain reaction.Results. …”
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139
Antihypertensive effect of sinapine extracted from rapeseed meal in 2K1C hypertensive rats
Published 2025-02-01“…The renin angiotensin aldosterone system (RAAS), including the levels of renin, angiotensin I (Ang I), angiotensin II (Ang II), aldosterone (ALD), angiotensin-converting enzyme (ACE) and other molecules related to blood pressure, such as NO, prostacyclin (PGI2), endothelin-1 (ET1), and thromboxane A2 (TXA2), were measured in rat blood. …”
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140
Carboxypeptidase B1 in dialyzed chronic kidney disease patients
Published 2025-02-01“…Abstract Carboxypeptidase B1 has long been known to be a pancreas-specific tissue enzyme. In this paper we focus on Carboxypeptidase B1 concentration measurement in dialyzed chronic kidney kidney disease patients and on the effect dialysis adequacy and regimen exert on its concentration. …”
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