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Genetic parameters and parental and early-life effects of boar semen traits
Published 2025-02-01Get full text
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363
Multi-locus CRISPRi targeting with a single truncated guide RNA
Published 2025-02-01“…Abstract A critical goal in functional genomics is evaluating which non-coding elements contribute to gene expression, cellular function, and disease. …”
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364
Infectious disease phylodynamics with occurrence data
Published 2021-08-01“…Abstract Phylodynamic models use pathogen genome sequence data to infer epidemiological dynamics. …”
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365
An oligodendrocyte silencer element underlies the pathogenic impact of lamin B1 structural variants
Published 2025-02-01“…Most cases of ADLD are caused by tandem genomic duplications involving the lamin B1 gene (LMNB1) while a small subset are caused by genomic deletions upstream of the gene. …”
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366
The distribution of allele frequencies of the 15 Short Tandem Repeats loci in Elazığ population, Turkiye
Published 2024-04-01“…The DNA within the Human Genome involves loci with high polymorphism such as short tandem repeats (STR). …”
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Opportunities for promoting open data in the Caribbean through biobanks
Published 2025-02-01“…It offers unprecedented insights into health data through extensive follow up and collection of genome-wide genotype data. H3Africa focuses on genomics research that addresses health disparities among African populations, which parallels the Caribbean’s challenges. …”
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Chronic wounds and adaptive Pseudomonas aeruginosa: A phenotypic and genotypic characterization
Published 2025-01-01“…This was performed using genomic and phenotypic approaches to understand the survival and persistence of Pseudomonas strains. …”
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370
Galloping into the Future: Genetic Tips and Tools for the Horse Owner
Published 2017-06-01“… This 4-page fact sheet discusses the equine genome, determining the genotype of a horse, breeding for certain traits, and the future of genetic tools. …”
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371
Galloping into the Future: Genetic Tips and Tools for the Horse Owner
Published 2017-06-01“… This 4-page fact sheet discusses the equine genome, determining the genotype of a horse, breeding for certain traits, and the future of genetic tools. …”
Get full text
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372
Overcoming immunotherapy resistance in gastric cancer: insights into mechanisms and emerging strategies
Published 2025-02-01“…We also discuss emerging strategies to overcome resistance, including combination therapies, novel immunotherapeutic approaches, and personalized treatment strategies based on tumor genomics and the immune microenvironment. By highlighting these key areas, this review aims to inform future research directions and clinical practice, ultimately improving outcomes for GC patients undergoing immunotherapy.…”
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373
The impact of social complexity on the efficacy of natural selection in termites
Published 2024-10-01“…In this study, we investigate the genomic consequences of eusociality in termites (Isoptera) on two different timescales. …”
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Simultaneous Inference of Past Demography and Selection from the Ancestral Recombination Graph under the Beta Coalescent
Published 2024-03-01“…The reproductive mechanism of a species is a key driver of genome evolution. The standard Wright-Fisher model for the reproduction of individuals in a population assumes that each individual produces a number of offspring negligible compared to the total population size. …”
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376
The impaired response of nasal epithelial cells to microplastic stimulation in asthma and COPD
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377
Protein arginine methyltransferase 7 linked to schizophrenia through regulation of neural progenitor cell proliferation and differentiation
Published 2025-02-01“…Summary: Genome-wide association studies (GWASs) have identified numerous genomic loci linked to schizophrenia (SCZ), while their pathogenic mechanisms largely remain unclear. …”
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378
Global biogeography and projection of antimicrobial toxin genes
Published 2025-02-01“…Results Here, we identified 4400 ATG clusters from 149 families by correlating 10,000 samples worldwide with over 200,000 microbial genome data. We demonstrated that global microbial communities universally encode complex and diverse ATGs, with widespread differences across various habitats. …”
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Hairy transcriptional repression targets and cofactor recruitment in Drosophila.
Published 2004-07-01“…This approach identified 40 novel genomic targets for Hairy in Kc cells, as well as 155 loci recruiting Groucho, 107 loci recruiting dSir2, and wide genomic binding of dCtBP to 496 loci. …”
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