Showing 221 - 240 results of 686 for search '"genomics"', query time: 0.06s Refine Results
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    In silico identification of switching nodes in metabolic networks by Mairet, Francis

    Published 2024-10-01
    Subjects: “…Genome-scale metabolic model, Branching point, Reporter metabolites, Flux Balance Analysis…”
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    Heterogeneity analysis provides evidence for a genetically homogeneous subtype of bipolar-disorder. by Caroline C McGrouther, Aaditya V Rangan, Arianna Di Florio, Jeremy A Elman, Nicholas J Schork, John Kelsoe, Bipolar Disorder Working Group of the Psychiatric Genomics Consortium

    Published 2025-01-01
    “…We first apply this covariate-corrected biclustering algorithm to a cohort of 2524 BD cases and 4106 controls from the Bipolar Disease Research Network (BDRN) within the Psychiatric Genomics Consortium (PGC). We find evidence of genetic heterogeneity delineating a statistically significant bicluster comprising a subset of BD cases which exhibits a disease-specific pattern of differential-expression across a subset of SNPs. …”
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