Economic and Humanistic Burden of Moderate and Severe Hemophilia A and B in Spain: Real-World Evidence Insights from the CHESS II Study by Carmen Peral, Alfonso De Lossada Juste, Nadia Lwoff, Nataly Espinoza-Cámac, Miguel Ángel Casado, Tom Burke, Jose Alvir, Sheena Thakkar, Enrico Ferri Grazzi

“…**Methods:** Spanish data from the CHESS II study (2018-2020) on patients' clinical characteristics, health-related quality of life (HRQoL) and hemophilia-related healthcare resource utilization were analyzed. Economic burden was determined by estimating condition-related annual per-patient direct (medical and nonmedical) and indirect costs, stratified according to hemophilia type and severity and presented as 2022 Euros. …”
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Gut Microbiota and Its Impact on Brain Function and Mental Health by Zofia Martyna Wójcik, Katarzyna Kamińska-Omasta, Bartosz Omasta, Olga Krupa, Paulina Dorota Pietrukaniec, Kuba Borys Romańczuk, Kinga Furtak, Szymon Przemysław Stolarczyk, Magdalena Agata Czerska, Daria Rybak

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Helicobacter pylori infection diagnostics and choice of eradication treatment: results of inquiry of doctors from different regions of Russian Federation by N. N. Dekhnich, R. S. Kozlov, O. A. Sablin, Ye. A. Prischepova

“…Overall 261 doctors of healthcare institutions in 15 cities of Russia (Orel, St. …”
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Exploring Acute Kidney Injury Incidence in Hip Periprosthetic Joint Infection Treatment With Combined Intravenous and Intra-articular Antibiotic Infusion by Wenbo Mu, MD, PhD, Boyong Xu, MD, Fei Wang, MD, Wentao Guo, MD, PhD, Xiaogang Zhang, MD, Li Cao, MD

“…Background: Periprosthetic joint infections (PJIs) are a significant complication following total hip arthroplasty, impacting patient health and healthcare costs. This study examines the incidence of acute kidney injury (AKI) in patients undergoing hip PJI treatment with a combination of intravenous and intra-articular antibiotic infusion therapies. …”
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Diagnostic Performance of Deep Learning Applications in Hepatocellular Carcinoma Detection Using Computed Tomography Imaging by Enes Şahin, Ozan Can Tatar, Mehmet Eşref Ulutaş, Sertaç Ata Güler, Turgay Şimşek, Nihat Zafer Utkan, Nuh Zafer Cantürk

“…As artificial intelligence technology continues to evolve, its integration into healthcare systems is expected to advance the accuracy and efficiency of diagnostics in oncology, enhancing early detection and treatment strategies and potentially improving patient survival rates.…”
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The Impact of Creatine Supplementation on Physical Performance, Cognitive Functions, and Safety – A Literature Review by Adam Sobiński, Matylda Czerwonka, Zuzanna Kościuszko, Katarzyna Kurza, Silvia Ciraolo, Julianna Podolec, Agnieszka Kulczycka-Rowicka, Katarzyna Lesiczka-Fedoryj, Joanna Wojda, Anna Walczak

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Impact of gas flaring on acute respiratory distress among pregnant women and newborn babies in Delta State Central Senatorial District, Nigeria by Omatseye Alero Akuirene, John Esimaje Moyegbone, Charity Omoikhekpen Chukumah, Mercy Ebiyemi Kalaroo, Josiah Obaghwerhievwo Adjene, Emmanuel Agbonomhen Agege, Joseph Onyedenyifa Odoko, Ezekiel Uba Nwose

“…Materials and methods: A descriptive cross-sectional survey involving 483 pregnant women of reproductive age, antenatal caregivers and healthcare professionals at health facilities in Delta State Central Senatorial District. …”
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A Study on Diagnostic Accuracy of Dipsi Method Over Traditional Oral Glucose Tolerance Test Among Antenatal Women by Vijayadevi Shanmugam, Dharani Sudha Gopalraj, Shruthi Nanjudappan, Rajeswari Ravindran

“…Failure to identify true positive cases could have significant clinical implications, impacting maternal and neonatal outcomes and overburdening healthcare systems. Further research with larger and diverse populations is needed to establish more accurate diagnostic thresholds for GDM using the DIPSI method or alternative criteria.…”
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Tough choices: the experience of family members of critically ill patients participating in ECMO treatment decision-making: a descriptive qualitative study by Xiangying Yang, Yao Lin, Amao Tang, Xiaokang Zeng, Weiying Dai, Qian Zhang, Li Ning

“…It may be difficult to improve the time it takes to make the decision without sacrificing the quality of the decision. Healthcare professionals should provide timely emotional support, informational support, and comprehensive social support to assist them in making efficient decisions while respecting the treatment preferences of the decision-makers.…”
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Pain Associated with Endometriosis. A Review of Quality of Life. Psychological Aspects, Career Development, Sexual Health, and Intimate Partner Relationships by Marlena Zubiak, Martyna Byrska, Hanna Barska-Kobylińska, Sara Langner, Ewa Katarzyna Malaka, Marta Janura, Jagoda Elias, Wiktor Biesiada, Sara Szydłowska, Krzysztof Błaszków

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Assessment of Blood Pressure Control Status Among Hypertensive Patients Attending Rwandan District Hospital NCD Clinics: A Retrospective Follow-Up Study by Evariste Ntaganda, Ziad El-Khatib, Regine Mugeni, Boniface Nsengiyumva, Clarisse Musanabaganwa, James Gafirita, Francois Uwinkindi, Richard Kalisa

“…Building the capacity of healthcare staff at both hospital and health centre levels is vital to improving hypertension management in NCD clinics.…”
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Indicators Of Morbidity And Mortality From Diseases of the Digestive System in the Krasnodar Krai and the Quality of Medical Care for Gastroenterological Patients by N. V. Korochanskaya, V. M. Durleshter, O. V. Kovalevskaya, S. N. Serikova, K. I. Popandopulo

“…The analysis was carried out according to C 51 “Distribution of deaths by gender, age groups and causes of death” form of the Territorial Authority of the Federal State Statistics Service for the Krasnodar Krai for the period from 2006 to 2018, as well as on the basis of the “Demography” block database of the Parus software of the healthcare management system of the Krasnodar Krai for 6 months of 2019. 1341 medical records of patients receiving outpatient medical care and the medical records of people who had died from digestive diseases in 2017-2019 were reviewed.Results. …”
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Cost-effectiveness of selective digestive decontamination (SDD) versus selective oropharyngeal decontamination (SOD) in intensive care units with low levels of antimicrobial resist... by Marc J M Bonten, Denise van Hout, Nienke L Plantinga, Patricia C Bruijning-Verhagen, Evelien A N Oostdijk, Anne Marie G A de Smet, G Ardine de Wit, Cornelis H van Werkhoven

“…Objective To determine the cost-effectiveness of selective digestive decontamination (SDD) as compared to selective oropharyngeal decontamination (SOD) in intensive care units (ICUs) with low levels of antimicrobial resistance.Design Post-hoc analysis of a previously performed individual patient data meta-analysis of two cluster-randomised cross-over trials.Setting 24 ICUs in the Netherlands.Participants 12 952 ICU patients who were treated with ≥1 dose of SDD (n=6720) or SOD (n=6232).Interventions SDD versus SOD.Primary and secondary outcome measures The incremental cost-effectiveness ratio (ICER; ie, costs to prevent one in-hospital death) was calculated by comparing differences in direct healthcare costs and in-hospital mortality of patients treated with SDD versus SOD. …”
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Probiogenomic analysis of Limosilactobacillus fermentum SD7, a probiotic candidate with remarkable aggregation abilities by Thunchanok Yaikhan, Monwadee Wonglapsuwan, Nuntiya Pahumunto, Natakorn Nokchan, Rawee Teanpaisan, Komwit Surachat

“…These findings provide a comprehensive understanding of the genetic composition of L. fermentum and its potential probiotic properties, identifying L. fermentum SD7 as a promising probiotic candidate for use in the food and healthcare industries.…”
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The immediate alteration of cerebellar Glx/GABA and cerebello-thalamo-cortical connectivity in patients with schizophrenia after cerebellar TMS by Chenyang Yao, Youjin Zhao, Qian Zhang, Ziyuan Zhao, Kai Ai, Bo Zhang, Su Lui

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Contribution of the Geodiversity knowledge to social, economic, and environmental health development by Cassio Silva, Edson Farias Mello, Gilberto Dias Calaes, Patricia Duringer Jacques, André Luiz Invernizzi

“…Regarding infrastructure, geosciences support both social (housing, sanitation, education, healthcare) and economic (energy, transportation, communications) developments. …”
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Effect of endoscopic sinus surgery on eustachian tube function in adult patients with chronic rhinosinusitis by Mahmoud Atef Abdelghaffar Youssef, Nassim Talaat Nassim, MohamedNourEddin Bashir Alkeeb, Tareq Muhammad Algarf

“…Abstract Background Chronic rhinosinusitis (CRS) is a frequent chronic heterogeneous inflammatory disease of the upper airways and paranasal sinuses persistent for ≥ 12 weeks causing considerable healthcare expenses and reduction of patients’ quality of life due to severe tiredness and disappointment as well as diminished cognitive function. …”
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Integrating a quality improvement experiential platform into medical student education by Amy S. Stanley, René M. Kronlage, Miranda J. Reid, Hannah G. Rains, Colleen J. Kalynych, Michele N. Lossius, Janice A. Taylor, Carolyn K. Holland

“…The aims were to assess students’ perceptions in regard to (1) student confidence in quality improvement (QI) methodology, and (2) competency in executing QI initiatives in healthcare as measured by a post-participation survey. …”
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Supporting older adults with mobility disabilities through voice-activated digital assistants and smart home technologies by Jaewon Kang, Emma Lachs, Kathryn Huang, Laura A. Rice, Wendy A. Rogers

“…Conclusion: Voice-activated digital assistants and smart home technologies have the potential to support older adults with mobility disabilities, assuming the right resources are provided to facilitate utilization. Healthcare professionals and researchers should recognize the unique benefits of these technologies for this population to promote their adoption and use effectively.…”
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Interdisciplinary collaboration across secondary and primary care to improve medication safety in the elderly (IMMENSE study): study protocol for a randomised controlled trial by Liv Mathiesen, Jeanette Schultz Johansen, Kjerstin Havnes, Kjell H. Halvorsen, Stine Haustreis, Lillann Wilsgård Skaue, Elena Kamycheva, Kirsten K. Viktil, Anne Gerd Granås, Beate H. Garcia

“…This paper presents the study protocol to explore the effects of the intervention with regard to healthcare use, health-related quality of life (HRQoL) and medication appropriateness in elderly patients.Methods and analysis A total of 500 patients aged ≥70 years will be included and randomised to control (standard care) or intervention group (1:1). …”
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