Fighting Alzheimer’s with Movement: The Role of Physical Activity in Disease Management by Agnieszka Kosińska, Magdalena Balwierz, Karolina Kalinowska, Urszula Świrk, Jan Karczmarz, Joanna Orzechowska, Marika Gutowska, Michał Orzechowski, Aleksandra Paprocka, Paulina Fijałek

“…The goal is to provide valuable insights for individuals and healthcare professionals on using physical activity as a non-pharmacological approach to managing Alzheimer's disease. …”
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Leveraging machine learning and rule extraction for enhanced transparency in emergency department length of stay prediction by Waqar A. Sulaiman, Charithea Stylianides, Andria Nikolaou, Andria Nikolaou, Zinonas Antoniou, Ioannis Constantinou, Lakis Palazis, Anna Vavlitou, Theodoros Kyprianou, Theodoros Kyprianou, Efthyvoulos Kyriacou, Antonis Kakas, Antonis Kakas, Marios S. Pattichis, Andreas S. Panayides, Constantinos S. Pattichis, Constantinos S. Pattichis

“…The findings highlight the importance of transparency in machine learning applications for healthcare, paving the way for future improvements in model performance and clinical adoption.…”
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Evaluation of spinal deformity and its progression in pyogenic spondylodiscitis: A retrospective MRI study of 59 cases by Andreas Kramer, Jonathan Neuhoff, Santhosh G. Thavarajasingam, Rebecca Sutherland, Hugh McCaughan, Benjamin Davies, Ehab Shiban, Florian Ringel, Andreas K. Demetriades

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Budget Impact of Rivaroxaban for the Prevention of Thromboembolic Events after Hip or Knee Replacement in Spain by Xavier Granero Xiberta, Antonio Murcia, José Ricardo Troncoso Durán, Claudio Gómez Zubeldia, Aleix Llorac Moix, Ruth Graefenhain De Codes, Maria Giovana Ferrario, Luis Lizán

“…Health care resources including pharmacologic prophylaxis, anesthesia and nurse care costs (Euros 2014) were estimated from the Spanish National Healthcare System (NHS) perspective. The annual cost associated with each cohort was estimated based on the mean cost per patient and the estimated distribution of use of rivaroxaban or enoxaparin in the base case scenario and alternative scenario (increase of rivaroxaban use) over the 3 years. …”
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Perioperative SARS-CoV-2 Infection in Patients Undergoing Elective Surgery in Gynecology Clinic: Tertiary Center Experience by Gulnihal Reyhan Toptas, Eylem Unlubilgin, Tugba Kinay, Ali Riza Dogan, Mehmet Akif Akgul, Sitare Aslanova, Emel Ebru Ercan, Vakkas Korkmaz, Sezin Erturk Aksakal, Yaprak Ustun

“…CONCLUSION: The results of our study show that gynecological surgical procedures do not increase the transmission and mortality rates of SARS-CoV-2 among patients and healthcare professionals as long as infection control measures are followed. …”
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Ethnobotany, floristic and phytochemical studies of medicinal plants used to treat uterine fibroids in Mbarara City, Uganda by Calton Nantinda, Esther Lynnet Kisakye, David Musana, Isaac Ssessanga, Ukashar Ssenabulya, Timothy Omara, Ivan Kahwa, Florence Nalimu

“…The TMPs play a vital role in the healthcare within this region, often incorporating conventional diagnostic methods such as ultrasound scans before providing herbal treatments. …”
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Quality of life and overall well-being between healthy individuals and patients with varied clinical diagnoses by Mohamad Adam Bujang, Wei Hong Lai, Xun Ting Tiong, Selvasingam Ratnasingam, Alex Ren Jye Kim, Masliyana Husin, Yvonne Yih Huan Jee, Nurul Fatma Diyana Ahmad, Clare Hui Hong Tan, Khoo Sing Yee, Yoon Khee Hon, Eileen Pin Pin Yap, Fazalena Johari, Alan Yean Yip Fong

“…Information regarding healthy participants was gathered from healthcare workers without any comorbidities. Data for non-healthy participants were collected from individuals diagnosed with various conditions across four specialist clinics: nephrology, oncology, psychiatry, and cardiology. …”
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Safety and effectiveness of different modes of labor induction among pregnant women delivering at referral hospitals in Dar es Salaam, Tanzania: a cohort study by Emmanuel Erasto, Martine A. Manguzu, Goodluck G. Nyondo, Manase Kilonzi, Alphonce Ignace Marealle, Ritah F. Mutagonda

“…Conclusion Oxytocin was the most effective and safest method for labor induction within 24 h, resulting in favorable maternal and neonatal outcomes. Healthcare workers should prioritize oxytocin for timely deliveries, while considering alternatives like dinoprostone, misoprostol, and balloon catheter based on individual patient needs and clinical circumstances.…”
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Cost-effectiveness of leveraging existing HIV primary health systems and community health workers for hypertension screening and treatment in Africa: An individual-based modeling s... by Matthew D Hickey, James Ayieko, Jane Kabami, Asiphas Owaraganise, Elijah Kakande, Sabina Ogachi, Colette I Aoko, Erick M Wafula, Norton Sang, Helen Sunday, Paul Revill, Loveleen Bansi-Matharu, Starley B Shade, Gabriel Chamie, Laura B Balzer, Maya L Petersen, Diane V Havlir, Moses R Kamya, Andrew N Phillips

“…<h4>Conclusions</h4>Leveraging existing healthcare infrastructure to implement population-level hypertension screening by CHWs and hypertension treatment through integrated chronic care clinics is expected to reduce CVD morbidity and mortality and is likely to be cost-effective in most settings across Africa.…”
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The search for a blood-based biomarker for Myalgic Encephalomyelitis/ Chronic Fatigue Syndrome (ME/CFS): from biochemistry to electrophysiology by Krista S. P. Clarke, Caroline C. Kingdon, Michael Pycraft Hughes, Eliana Mattos Lacerda, Rebecca Lewis, Emily J. Kruchek, Robert A. Dorey, Fatima H. Labeed

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Evaluating the relative predictive validity of measures of self-referential processing for depressive symptom severity by Ethel Siew Ee Tan, Hong Ming Tan, Kah Vui Fong, Sheryl Yu Xuan Tey, Nikita Rane, Chong Wei Ho, Zhao Yuan Tan, Rachel Jing Min Ong, Chloe Teo, Jerall Yu, Maxine Lee, An Rae Teo, Sin Kee Ong, Xin Ying Lim, Jin Lin Kee, Jussi Keppo, Geoffrey Chern-Yee Tan

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Mental health literacy and associated factors among traditional healers of Jimma town, southwest, Ethiopia 2020: a community based, cross-sectional study by Gudeta Mideksa, Elias Tesfaye, Yimenu Yitayih, Yohanes Sime, Kemal Aliye, Abraham Tamirat Gizaw

“…BackgroundTraditional healers are in the front line to give the mental healthcare service in developing countries like Ethiopia. …”
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A Pragmatic Clinical Trial to Compare the Real-World Effectiveness of V-Go versus Standard Delivery of Insulin in Patients with Advanced Type 2 Diabetes by Mark J. Cziraky, Scott Abbott, Matt Nguyen, Kay Larholt, Elizabeth Apgar, Thomas Wasser, Poul Strange, Leon Shi, H. Courtenay Harrison, Beverly Everitt, Lynn Nowak

“…**Background:** Many patients with type 2 diabetes mellitus (T2DM) do not have adequate glycemic control, leading to poor patient outcomes and high healthcare costs. **Objective:** This prospective pragmatic clinical trial evaluated V-Go, a wearable insulin delivery device, compared with standard treatment optimization (STO) among insulin-treated patients with T2DM in a realworld, community-based practice setting. …”
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Enhancing Semi-Supervised Learning With Concept Drift Detection and Self-Training: A Study on Classifier Diversity and Performance by Jose L. M. Perez, Roberto S. M. Barros, Silas G. T. C. Santos

“…Machine learning algorithms that assist in decision-making are becoming crucial in several areas, such as healthcare, finance, marketing, etc. Algorithms exposed to a larger and more relevant amount of training data tend to perform better. …”
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Feasibility study to assess the delivery of a lifestyle intervention (TreatWELL) for patients with colorectal cancer undergoing potentially curative treatment by Annie S Anderson, Ronan E O’Carroll, Martine Stead, Robert J C Steele, Mary Wells, Maureen Macleod, Anna Campbell, Jacqui A Sugden, Jackie Rodger, Jennifer McKell

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Trisomy 21 screening with αlpha software and the Fetal Medicine Foundation algorithm by L Pistorius, C A Cluver, I Bhorat, L Geerts

“…To determine the screen positive and detection rates of prenatal screening for trisomy 21 in the SA private healthcare system. Methods. Data from the three largest laboratories collected between 2010 and 2015 were linked with genetic tests to assess screen positive and detection rates. …”
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TOURISM study (Treatment Outcomes in UteRIne SarcoMa): a 10-year retrospective evaluation of practice in the UK by Rebekah Webb, Mohammed Al-Zubaidi, Mark A Baxter, Karin Purshouse, James Robertson, Helen Creedon, Katherine Fair, Asma Sarwar, Laura Hannington, Adam L Peters, Samuel Mcinerney, Karen E Mactier, Georgina E Wood, Mai K Bishr, Leonie Eastlake, Katharine Lankester, Alison L Stillie

“…Treatment options and robust trial data are limited.Objectives The TOURISM study (Treatment Outcomes in UteRIne SarcoMa) is a UK-wide study by the National Oncology Trainees Collaborative for Healthcare Research which aimed to characterise this patient cohort.Design A retrospective descriptive cohort study. …”
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Establishing primary care physician commitment in Canadian long-term care homes: a protocol for a modified e-Delphi study by Andrew P Costa, Aaron Jones, Darly Dash, Paula Rochon, Patrick Quail, Rachel D Savage, Henry Yu-Hin Siu, Lisa M McCarthy, Nathan Stall, Dee Tripp, Maya Potter, Paul Katz, Samantha Peck

“…We aim to establish consensus on expectations concerning PCP commitment in Canadian LTC homes.Methods and analysis We describe a protocol for a two-round modified e-Delphi study assessing the consensus of an expert panel, guided by the RAND methodological guidance for conducting Delphi panels and the ACcurate COnsensus Reporting Document (ACCORD) guideline for healthcare-based consensus studies. We will recruit pan-Canadian experts who demonstrate extensive knowledge and experience in medical care delivery and medical practice models in the Canadian LTC sector. …”
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Randomised controlled trial of topical kanuka honey for the treatment of rosacea by James Fingleton, Mark Weatherall, Richard Beasley, Irene Braithwaite, Janwillem Kocks, Mark Holliday, Andrew Corin, Colin Helm, Davitt Sheahan, Barney Montgomery, Judith Riley, Anna Hunt, Christopher Tofield

“…Objective To investigate the efficacy of topical 90% medical-grade kanuka honey and 10% glycerine (Honevo) as a treatment for rosacea.Design Randomised controlled trial with blinded assessment of primary outcome variable.Setting Outpatient primary healthcare population from 5 New Zealand sites.Participants 138 adults aged ≥16, with a diagnosis of rosacea, and a baseline blinded Investigator Global Assessment of Rosacea Severity Score (IGA-RSS) of ≥2. 69 participants were randomised to each treatment arm. 1 participant was excluded from the Honevo group, and 7 and 15 participants withdrew from the Honevo and control groups, respectively.Interventions Participants were randomly allocated 1:1 to Honevo or control cream (Cetomacrogol), applied twice daily for 8 weeks.Main outcome measures The primary outcome measure was the proportion of participants who had a ≥2 improvement in the 7-point IGA-RSS at week 8 compared to baseline. …”
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Multinational comparison of new antidepressant use in older adults: a cohort study by Robyn Tamblyn, David Westfall Bates, David L Buckeridge, Will Dixon, Alan J Forster, Nadyne Girard, Jennifer Haas, Bettina Habib, Siyana Kurteva, Jack Li, Therese Sheppard

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