An Update on African Trypanocide Pharmaceutics and Resistance. by Keneth Iceland, Kasozi, MacLeod, Ewan Thomas, Ntulume, Ibrahim, Welburn, Susan Christina

“…African trypanosomiasis is associated with Trypanosoma evansi, T. vivax, T. congolense, and T. brucei pathogens in African animal trypanosomiasis (AAT) while T. b gambiense and T. b rhodesiense are responsible for chronic and acute human African trypanosomiasis (HAT), respectively. …”
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Meta-analysis of the association between overexpression of RAD51 family genes and prognosis and clinical features in breast cancer by Yong-Cheng Liu, Jun Shen

“…Regarding clinical characteristics, high expression of RAD51 family genes was significantly associated with human epidermal growth factor receptor 2 (HER2) positivity [OR = 1.782, 95%CI (1.328–2.392), P < 0.01]. …”
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Aplikasi Jurnal Harian Covid-19 untuk Pemantauan Isolasi Mandiri (PISOM) by Mutiara Anggun, Margaretha Amanda, Tri Ahmad Sandi, Rinto Priambodo

“…Abstract Coronavirus disease 2019 (Covid-19) is an infectious disease, caused by the SARS-CoV-2 virus which affects the respiratory system in the human body and can result in death. Hundreds of millions of cases have been reported in different countries and regions. …”
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Performance of emergency triage prediction of an open access natural language processing based chatbot application (ChatGPT): A preliminary, scenario-based cross-sectional study by İbrahim Sarbay, Göksu Bozdereli Berikol, İbrahim Ulaş Özturan

“…OBJECTIVES: Artificial intelligence companies have been increasing their initiatives recently to improve the results of chatbots, which are software programs that can converse with a human in natural language. The role of chatbots in health care is deemed worthy of research. …”
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Klasifikasi Pola Pergerakan Bola Mata Menggunakan Metode Multilayer Backpropagation by Karina Amadea, Fitra A. Bachtiar, Gusti Pangestu

“…Abstract  Eye is one of the most important organs in the human body. By using the eye, humans can get as much as 80% of information just by looking. …”
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New insights into the mechanism of triphenyl phosphate and its metabolite diphenyl phosphate in diabetic kidney disease by Ting Fang, Qiaoyan Liu, Xinxin Huangfu, Hongkai Zhu, Hongwen Sun, Liming Chen

“…The results indicated statistically significant regulation of most core targets by TPHP and DPHP in MPC5, MES13, and human kidney-2 cells.…”
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A guide to selecting high-performing antibodies for Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform (PPP2R5D) for use in Western Blot, immunoprecipi... by Carl Laflamme, Kathleen Southern, Riham Ayoubi, Maryam Fotouhi, Charles Alende

“…These studies are part of a larger, collaborative initiative seeking to address antibody reproducibility by characterizing commercially available antibodies for human proteins and publishing the results openly as a resource for the scientific community. …”
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Increasing the uptake of long-acting reversible contraception in general practice: the Australian Contraceptive ChOice pRoject (ACCORd) cluster randomised controlled trial protocol by Danielle Mazza, Angela Taft, Kevin McGeechan, Kirsten Black, Heather McKay, Marion Haas, Jayne Lucke, Jeffery F Peipert

“…The costs and outcomes of the intervention and control will be compared in a cost-effectiveness analysis.Ethics and dissemination The ACCORd study has been approved by the Monash University Human Research Ethics Committee: CF14/3990-2014002066 and CF16/188-2016000080. …”
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Pilates exercise in pregnancy: a systematic review and meta-analysis by Yuxuan Li, Heran Lu, Liuwei Zhang, Yijia Ren, Xiaotong Dai, Lin Lin

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Inosine enhances the efficacy of immune‐checkpoint inhibitors in advanced solid tumors: A randomized, controlled, Phase 2 study by Haiqing Zhao, Wei Zhang, Yuting Lu, Yin Dong, Zhihao He, Hongchao Zhen, Qin Li

“…Abstract Background This study aimed to evaluate whether inosine enhances the efficacy of immune‐checkpoint inhibitors in human malignant solid tumors. Methods This single‐center, prospective, randomized, open‐label study was conducted, from January 2021 to December 2022, in Beijing Friendship Hospital, Capital Medical University, and participants were randomly assigned (1:1) to either the inosine (trial) or non‐inosine (control) group that received inosine (dosage: 0.2 g, three times/day) + PD‐1/PD‐L1 inhibitor or only PD‐1/PD‐L1 inhibitor ± targeted ± chemotherapy, respectively. …”
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Tata Kelola Teknologi Informasi Pada Sektor Publik: Penyelarasan Teknologi Informasi Dengan Visi Kepemimpinan (Studi Kasus: Kota Salatiga dan Kabupaten Bengkayang) by Andeka Rocky Tanaamah, Agustinus Fritz Wijaya, Sarah Ayu Maylinda

“…This study found factors that play a role such as the commitment of the regional head, the ability to describe the vision and mission, the availability of regulations and rules, support for implementing IT, the ability to consolidate and manage, institutional structuring, support, and budget allocation, availability of infrastructure, resources human resources, and the ability to develop implementation strategies. …”
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Weight Change and Predictors of Weight Change Among Patients Initiated on Darunavir/Cobicistat/Emtricitabine/Tenofovir Alafenamide or Bictegravir/Emtricitabine/Tenofovir Alafenamid... by Bruno Emond, Carmine Rossi, Aurélie Côté-Sergent, Keith Dunn, Patrick Lefebvre, Marie-Hélène Lafeuille, Prina Donga

“…**Background:** Recent evidence suggests that integrase strand transfer inhibitors are associated with greater weight gain than protease inhibitors in patients with human immunodeficiency virus (HIV-1). **Objectives:** To describe demographic and clinical characteristics of insured patients with HIV-1 in the United States initiating darunavir/&#8203;cobicistat/&#8203;emtricitabine/&#8203;tenofovir alafenamide (DRV/c/FTC/TAF) or bictegravir/FTC/TAF (BIC/FTC/TAF), assess the differences in weight and body mass index (BMI) change between cohorts up to one year after treatment initiation, and identify the predictors of weight gain associated with each treatment. …”
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Sistem Deteksi Myocardial Infarction Berdasarkan Pathological Q Waves Dan ST Segment Elevation Menggunakan Metode Support Vector Machine by Ragil Hadi Prasetyo, Edita Rosana Widasari, Agung Setia Budi

“…Abstract Heart is a very important organ for the human body because if you experience a disorder of the heart it will have a big impact on the body. …”
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Artificial Intelligence–Powered Training Database for Clinical Thinking: App Development Study by Heng Wang, Danni Zheng, Mengying Wang, Hong Ji, Jiangli Han, Yan Wang, Ning Shen, Jie Qiao

“… Abstract BackgroundWith the development of artificial intelligence (AI),ntered the era of intelligent medicine ObjectiveThis study aimed to introduce an app named “XueYiKu,” which includes consultations, physical examinations, auxiliary examinations, and diagnosis, incorporating AI and actual complete hospital medical records to build an online-learning platform using human-computer interaction. MethodsThe “XueYiKu” app was designed as a contactless, self-service, trial-and-error system application based on actual complete hospital medical records and natural language processing technology to comprehensively assess the “clinical competence” of residents at different stages. …”
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Investigating the Feasibility of Behavioral Nudges to Reduce the Phenomenon of Escape from Responsibility in Public Sector by Seyed Kamal Vaezi, Mahboubeh Hosseini

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REGIONAL FACTORS OF MECHANISMS TRANSFORMATION FOR STRENGTHENING THE ECONOMIC SECURITY OF ENTREPRENEURIAL ACTIVITY IN THE INDUSTRIAL SECTOR OF UKRAINE by Tetyana Calinescu, Olena Zelenko, Serhii Pidmohylnyi

“…Results of the study: it is determined that the formation of economic security of entrepreneurial activity in the industrial sector of Ukraine at the regional level is carried out by increasing the volume of sales of products/services against the background of ensuring the resource, production, scientific, technical, human resources potential, provided that the welfare of employees and the absence of inflation; an instrumentarium for assessing the status of economic security of entrepreneurial activity in the industrial sector at the regional level has been defined, which provides for the analysis of individual coefficients with a threshold value, as well as the calculation of an integral indicator of the status of economic security of entrepreneurial activity in the industrial sector of the region; the article characterises modern factors of formation of economic security of entrepreneurial activity at the level of regions of Ukraine, in particular, the most promising branches of the industrial sector for a particular region of Ukraine and the standard of living of the economically active population with the status of internally displaced persons. …”
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Cetacean feeding modelling using machine learning: A case study of the Central-Eastern Mediterranean Sea by Carla Cherubini, Giulia Cipriano, Leonardo Saccotelli, Giovanni Dimauro, Giovanni Coppini, Roberto Carlucci, Carmelo Fanizza, Rosalia Maglietta

“…Investigating environmental drivers of cetacean feeding behaviour is essential for effective marine resource management, especially in the Mediterranean Sea, a biodiversity hotspot heavily impacted by human activities and climate change. This study realized a pioneer assessment of feeding activity related to the marine environment for three cetacean species - striped dolphin, common bottlenose dolphin, and Risso's dolphin - in the Gulf of Taranto (Northern Ionian Sea, Central-eastern Mediterranean) using an innovative Machine Learning (ML) approach. …”
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Enhancing collaborative clinical reasoning among multidisciplinary healthcare teams in a neurosurgery ICU: insights from video-reflexive ethnography by Ching-Yi Lee, Ching-Hsin Lee, Sze-Yuen Yau, Hung-Yi Lai, Po-Jui Chen, Mi-Mi Chen

“…Clinical trial number Not required, as this is not a clinical trial and does not involve any healthcare interventions with human participants.…”
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Inhibition of tumour necrosis factor alpha by Etanercept attenuates Shiga toxin-induced brain pathology by Robin Christ, Devon Siemes, Shuo Zhao, Lars Widera, Philippa Spangenberg, Julia Lill, Stephanie Thiebes, Jenny Bottek, Lars Borgards, Andreia G. Pinho, Nuno A. Silva, Susana Monteiro, Selina K. Jorch, Matthias Gunzer, Bente Siebels, Hannah Voss, Hartmut Schlüter, Olga Shevchuk, Jianxu Chen, Daniel R. Engel

“…Analysis of microglial populations using a novel human-in-the-loop deep learning algorithm for the segmentation of microscopic imaging data indicated specific morphological changes, which were reduced to healthy condition after inhibition of TNF-α. …”
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Association between sleep during pregnancy and birth outcomes: a prospective cohort study by Libing Huang, Huanjun Chen, Fuhui Yao, Zhonghan Sun, Shijiao Yan, Yuwei Lai, Chuanzhu Lv, Xiong-Fei Pan, Rixing Wang, Xingyue Song

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