Acceptability and Implementation Challenges of Benzathine Penicillin G Secondary Prophylaxis for Rheumatic Heart Disease in Ethiopia: A Qualitative Study by Eshetie Melese Birru, Kevin T. Batty, Laurens Manning, Stephanie L. Enkel, Brioni R. Moore

“…Highlights: • Key barriers included (a) resistance from healthcare providers to administer benzathine penicillin G (BPG) due to their concerns about injection-related severe adverse events, and potential repercussions should an event occur, (b) poor community and healthcare provider awareness of the disease and its treatment, (c) lack of resources to manage adverse events, and (d) injection pain. • Key enablers included (a) perceived superior treatment benefits of BPG and (b) co-administration of lidocaine/analgesics to reduce injection pain. • Recommendations to address identified challenges include (a) improved training/education on RHD diagnosis, disease progression, and treatment, (b) improved access to supportive resources, (c) active adverse reaction monitoring and reporting, and (d) encouraging the provision/access of globally subsidized BPG suspension formulations in pre-filled syringes.…”
Get full text

Overview of preclinical and phase II clinical studies on Pegmolesatide’s long-term erythropoiesis stimulating effect via EPOR-mediated signal transduction by Xiaoying Ma, Zhen Li, Lu Zhang, Hui Qian, Qinkai Chen, Ye Tao, Yunfan Li, Dandan Wang, Zhizhen Hu, Weili Luo, Ping Li, Hai Yu, Changlin Mei, Xueqing Yu, Yuanfeng Zhou

“…Adverse events were mild and manageable, with no reports of severe anaphylaxis. Discussion Preclinical and clinical evidence signifies that Pegmolesatide is a unique, potent PEGylated EPO-memetic peptide (EMP) with a prolonged PD efficacy and PK half-life and a good safety-tolerability profile. …”
Get full text

Balneotherapy for the treatment of post-COVID syndrome: a randomized controlled trial by Diana Ovejero, Anna Ribes, Judit Villar-García, Marta Trenchs-Rodriguez, Daniel Lopez, Xavier Nogués, Robert Güerri-Fernandez, Natalia Garcia-Giralt

“…Abstract Background Post-Acute COVID Syndrome (PACS) is a complex disorder that currently lacks effective evidenced-based therapies to manage it. This randomized controlled trial aims to evaluate the effects of balneotherapy (BT) on PACS symptomatology. …”
Get full text

Evaluation of Performance Metrics Required in Proper Selection of SDN Controller for Integrated Satellite-Terrestrial Networks by Oluwatobi A. Ayofe, Mu'azu J. Musa, Zanna M. Abdullahir, Abdoulie M.S. Tekanyi, Aliyu D. Usman, Ezekiel E. Agbon, Emmanuel A. Otsapa, Agburu O. Adikpe, Matthew Iyobhebhe, Paul Thomas Muge

“… SDN controllers are increasingly becoming an integral part of modern communication networks due to their ability to centrally control and manage networks from a global point of view. One of the application areas in which the SDN paradigm is gaining traction is the Integration of Satellite and Terrestrial Networks (ISTN). …”
Get full text

Rancang Bangun Purwarupa Pemilah Sampah Pintar Berbasis Deep Learning by Kahlil Muchtar, Nyak Twoman Anshari, Chairuman Chairuman, Khalid Alhabibie, Khairul Munadi

“…According to the latest research by Sustainable Waste Indonesia (SWI) 24% of waste in Indonesia is still not properly managed. From about 65 million tons of waste produced in Indonesia every day, the largest contributor to this is organic waste as much as 60%, plastic waste 14%, followed by paper waste 9%, metal 4.3%, glass, wood and other materials at 12.7%. …”
Get full text

Sistem Kendali Perangkat Elektronik Jarak Jauh Berbasis Jaringan Nirkabel Menggunakan Secure Shell (SSH) dan robot Operating System (ROS) by Abdul Jalil

“…The methodology has used to manage the electronic devices in this study is used Remote Access Control (RAC) based on SSH protocol. …”
Get full text

Hubungan Antara Cache, Energy Consumption dan Runtime Performance pada Progressive Web Apps by Wakhid Kurniawan, Agung Fatwanto

“…Service Workers at the core have the ability to intercept and handle network requests, including managing programmatic response caches. All Service worker capabilities are cached. …”
Get full text

Implementasi VPN Antar Cabang Menggunakan Teknologi SDWAN dengan Metode Load Balance (Studi Kasus: PT. Mitra Solusi Infokom) by Muhammad Fikri, Muhammad Rifqi

“…Abstract The rapid development of network communication, the process of managing and monitoring the network will be more complex. …”
Get full text

Designing a Model for Credit Risk Assessment of Customers for Guarantees Issued by the Export Guarantee Fund of Iran via Artificial Neural Network Model by Farshid Ahmadi Sartakhti, Kambiz Hojabr Kiani, Seyed Shamsoddin Hoseini, Abbas Memarnejad

“…In this case, while measuring the credit risk and separating customers, it is possible to manage the risk and the credit portfolio of the Export Guarantee Fund of Iran optimally.…”
Get full text

Analysis of the Spatial Pattern of Military River Defense on the Ming Great Wall: A Case Study of the Shanxi Section of the Yellow River by Tianlian WANG, Zhe LI

“…This includes expanding corner ramparts for frontal enemy protection and incorporating passes and water gates on border walls to manage water flow. Using data extracted from historical aerial photos and 3D Real Scene point cloud, the original historical original appearance of Hequying City (a river defense node) and its border walls is restored.ConclusionDriven by the intricate river water environment and military defense demands, a layered military defense network has emerged within the spatial pattern of river defense, and a comprehensive defense layout has been established by fully leveraging the natural terrain. …”
Get full text

Visualisasi Data Kriminal Wilayah Polres Musi Banyuasin by Fitri Purwaningtias, Muhamad Ariandi, Maria Ulfa

“…The purpose of this research is to help Sat Tahti employees in managing data on criminal prisoners quickly and easily using this Tableau and also being able to present graphic reports that are easy to read and understand by the Head of the MuBa Police. …”
Get full text

Inappropriate medication prescribing, polypharmacy, potential drug-drug interactions and medication regimen complexity in older adults attending three referral hospitals in Asmara,... by Nuru Abdu, Saleh Idrisnur, Hanae Said, Lude Kifle, Natnael Habte, Semira Ghirmai, Tomas Tewelde, Senai Mihreteab Siele, Eyasu H. Tesfamariam

“…Conclusion Inappropriate medication prescribing and clinically significant drug-drug interactions were common among older adults, highlighting the need for immediate attention from policymakers, program managers, and healthcare professionals.…”
Get full text

Analisis Kualitas Website Balai Besar Taman Nasional Gunung Gede Pangranggo (BBTNGGP) menggunakan Metode Webqual 4.0 by Muhammad Syahid Qadhafi, Atit Pertiwi

“…Such as limited payment methods for ordering Conservation Area Entry Permits (SIMAKSI) online, less attractive website appearance, less efficient quality of information where visitors register online by taking tickets and health checks offline, quality of interaction services between national park managers and visitors who have not been maximized. …”
Get full text

Perancangan User Experiance Website Travel Mabruro Menggunakan Pendekatan Human-Centered Design by Safira Nur Rahmah, Hanifah Muslimah Az- Zahra, Yusi Tyroni Mursityo

“…However because of the COVID-19 pandemic, Travel Mabruro need online services in managing registration and administration to reduce physical contact, for this reason Travel Mabruro utilizes a previously owned website to add these services. …”
Get full text

Zolpidem: Efficacy and Side Effects for Insomnia by Amber N. Edinoff, Natalie Wu, Yahya T. Ghaffar, Rosemary Prejean, Rachel Gremillion, Mark Cogburn, Azem A. Chami, Adam M. Kaye, Alan D. Kaye

“…The treatment of insomnia should involve a multi-disciplinary approach, focusing on implementing behavioral interventions, improving sleep hygiene, managing psychological stressors, hypnotic treatment, and pharmacological therapy. …”
Get full text

A Prospective, Crossover, Randomized, Double-Blind Clinical Study Comparing the Effectiveness and Ocular Comfort of 0.1% Hyaluronic Acid and 0.3% Hyaluronic Acid in Patients With D... by Kim SJ, Yoo WS, Kwon LH, Kim RB, Yoon HJ, Yoon KC

“…Using these eye drops in a personalized treatment plan can help people with DED manage their symptoms better and lead more comfortable lives.Keywords: dry eye disease, 0.1% hyaluronic acid, 0.3% hyaluronic acid…”
Get full text

Evaluation de la qualité de vie des femmes souffrant d’une fistule obstétricale à Kinshasa [Evaluation of the quality of life of women with obstetric fistula in Kinshasa] by Jonathan Enguta Mwenzi, Ruth Bukabau Babuya, Francine Manyonga Sabowa

“…Methods - We used a survey method supported by the McGill Quality of Life Scale, which we administered to a sample of 56 women with obstetric fistula managed at the Fistula Clinic in Kinshasa. Results -In terms of socio-demographic variables, the study sample consisted of 20 women under the age of 30, 15 aged 30-39 and 21 aged 40-49. …”
Get full text

Fálétí’s Philosophical Sensibility by Adeshina Afolayan

“…In Irele and Gikandi’s edited volumes, The Cambridge History of African and Caribbean Literature (2004), Fálétí only managed an appearance in the bibliography that featured four of his works—Wọn Rò Pé Wèrè Ni ́ (1965), Ọmọ Olókùn Ẹṣin (1969), Baṣòrun Gáà (1972) and Ìdààmú Páàdì Mínkáílù (1974). …”
Get full text

Efficacy of Alginate-Antacid Medication in the Treatment of Patients with Gastroesophageal Reflux Disease by O. A. Storonova, A. S. Trukhmanov, V. T. Ivashkin

“…The inclusion of alginate-antacid medication into treatment schemes for managing ERD patients significantly increases its effectiveness, reliably increasing the rate of the onset of the clinical effect. alginate-antacid medication is shown to be an effective monotherapy for NERD. …”
Get full text

IGJR 1/2020: Housing crisis: How can we improve the situation for young people? by IF and FRFG

“…An EU comparison shows that the percentage of households managed by a person aged 18–29 who spends 40% or more of their disposable income on housing costs ranges from 1.3% (in Malta) to 45.4% (in Greece) (Leach et al. 2016). …”
Get full text