Screening Southeast Asian medicinal plants: Clausena lansium, Leea indica, Strobilanthes crispa, Vitex trifolia for anti-platelet aggregation and blood coagulation effects by Sogand Zareisedehizadeh, Fu-Xun Heng, Chay-Hoon Tan, Paul Chi-Lui Ho, Hwee-Ling Koh

“…Liquid chromatography and time of flight mass spectrometry (LC-ToF-MS) analysis of Leea indica revealed gallic acid, methyl gallate, epigallocatechin, epigallocatechin-3-O-gallate, and other polyphenolic compounds. …”
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Ion suppression correction and normalization for non-targeted metabolomics by Iqbal Mahmud, Bo Wei, Lucas Veillon, Lin Tan, Sara Martinez, Bao Tran, Alexander Raskind, Felice de Jong, Yiwei Liu, Jibin Ding, Yun Xiong, Wai-kin Chan, Rehan Akbani, John N. Weinstein, Chris Beecher, Philip L. Lorenzi

“…Abstract Ion suppression is a major problem in mass spectrometry (MS)-based metabolomics; it can dramatically decrease measurement accuracy, precision, and sensitivity. …”
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Drosophila ubiquitin-specific peptidase 14 stabilizes the PERIOD protein by regulating a ubiquitin ligase SLIMB by So Who Kang, Jung-Eun Park, Soonhyuck Ok, Minhui Um, Hyeonjeong Son, Seunghee Byun, Nayoung Park, Su Jin Lee, Thị Xuân Thùy Trần, Gyeongmin Kim, Jeonghun Yeom, Kyunggon Kim, Eun Young Kim, Min-Ji Kang

“…Moreover, reducing slimb expression mitigates the effects of USP14 on PER protein stability. Mass spectrometry identifies two ubiquitination sites on PER (Lys1117 and Lys1118) critical for its degradation. …”
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Exposure to Silica, Arsenic, and Chromium (VI) in Cement Workers: A Probability Health Risk Assessment by Noor Haziqah Kamaludin, Juliana Jalaludin, Shamsul Bahri Mohd Tamrin, Abdah Md Akim, Tri Martiana, Noeroel Widajati

“…Inductively coupled plasma mass spectrometry (ICP-MS) was used for As, and Cr analysis, and X-ray powder diffraction (XRD) was used for Si analysis. …”
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Simultaneous Determination of Multiple Acid-Suppressing Drugs by UPLC-MS/MS Method and Application for Pharmacokinetics Study by Li X, Liu S, Yu M, Xi W, Wu X, Liu D, Liu A, Wang H

“…Precisely quantifying their plasma levels is crucial for clinical pharmacokinetic assessments and therapeutic drug monitoring.Aim: This study aimed to establish a generic and efficient ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) assay for the determination of five PPIs (esomeprazole, rabeprazole, ilaprazole, lansoprazole, and pantoprazole) and the P-CAB (vonoprazan) in human plasma.Methods: The six analytes were extracted from human plasma via protein precipitation and a single dilution step. …”
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Microbial community succession characteristics in an anaerobic baffled reactor during phenol gradient acclimation by Yuan LI, Chunmei YU, Daqiang CANG

“…Phenol degradation intermediates were performed using gas chromatography/mass spectrometry (GC–MS), with their quantities measured by high-performance liquid chromatography. …”
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Assessment of the essential oil extracted from Citrus aurantifolia leaves using solvent-free microwave extraction technique by G.M. Masud Rana, Md. Jasim Uddin, Jaytirmoy Barmon, Bijoy Chandra Ghos, Tahmina Akter Chowdhury, Amit Kumar Dey, Bijoy Maitra, Ismat Moin Tamanna, AHM Mahbubur Rahman, Barun Kanti Saha, Mst. Sarmina Yeasmin

“…Gas chromatography-mass spectrometry (GC–MS) profiling revealed multiple bioactive components in C. aurantifolia leaves EO, with neral (30.728 %), d-limonene (22.824 %), citral (19.430 %), lemonol (5.060 %), geraniol (3.447 %), geranial (3.079 %), and caryophyllene (3.959 %) being the major components. …”
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Smart packaging tools for selected Indian traditional buffalo milk products: a case for on-package freshness indicators by Narender Raju Panjagari, Ashish Kumar Singh, Sangita Ganguly, Rajan Sharma, Vivek Sharma

“…The prerequisites for developing freshness indicators were to identify the critical volatile headspace markers using solid phase microextraction (SPME) coupled with gas chromatography-mass spectrometry (GC-MS) for the respective dairy products, selection of suitable innovative ink components, namely dyes (methyl red, and methyl red sodium salt), plasticizer (glycerol), choose appropriate polymer support (methylcellulose, polyvinyl alcohol or paper), and adopt a suitable production technique such as casting, dipping, or electrospinning. …”
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Tracing the change of the volatile compounds of soy sauce at different fermentation times by PTR-TOF-MS, E-nose and GC–MS by Qixin Kan, Longbipei Cao, Liping He, Peipei Wang, Guangdie Deng, Jun Li, Jiangyan Fu, Qingrong Huang, Chi-Tang Ho, Yunqi Li, Chunhui Xie, Yong Cao, Linfeng Wen

“…Proton-transfer reaction time-of-flight mass spectrometry (PTR-TOF-MS), combined with electronic nose (E-nose), was first used to track the change of volatile organic compounds (VOCs) in soy sauce in this study. …”
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Quantitative proteomics and targeted metabolomics reveal the role of Cassia siamea L. extract in the response to high-fat diet-induced obesity in Drosophila by Ananya Dechakhamphu, Nattapong Wongchum, Theeraphan Chumroenphat, Alongklod Tanomtong, Sirithon Siriamornpun

“…Methods: CSE was obtained via extraction from C. siamea wood with 70 % ethanol and its phytochemical content was analyzed by gas chromatography–mass spectrometry (GC‒MS) and high-performance liquid chromatography (HPLC). …”
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The effects of Thymus capitatus essential oil topical application on milk quality: a systems biology approach by Ralph Nehme, Chiara Gini, Elise Vanbergue, Sergine Even, Filippo Biscarini, Sonia Andrés, Lucie Rault, Faustine Noel, Valerie Hardit, Said Bouhallab, David M. Pereira, Riadh Ksouri, Philippe Roussel, Secundino López, Paola Cremonesi, Bianca Castiglioni, Donatella Caruso, Fiorenza Faré, Manuela Fontana, Fabrizio Ceciliani, Latifa Abdennebi-Najar

“…This study aimed to investigate the impact of Thymus capitatus essential oil (TCEO), known for its high antibacterial and antioxidant properties, on milk microbiota using 16S rRNA sequencing, the lipidomic profile via liquid chromatography-quadrupole time-of-flight mass spectrometry, udder skin microbiota, and inflammatory biomarkers of dairy cows at the end of lactation. …”
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Systemic delivery of AAV5, AAV8, and AAV9 packaging a C5-12-microdystrophin-FLAG expression cassette in non-human primates by Mengping Liu, Erica Cook, Yanshan Dai, Erich Ehlert, Francois du Plessis, Jacek Lubelski, Bogdan G. Sleczka, Petia Shipkova, Zhuyin Li, Joshua Gamse, David Gordon, Leonard P. Adam, Paul C. Levesque, Glen B. Banks

“…At 1 month post-dose, we compared tissue vector genomes, mRNA, and microdystrophin-FLAG protein levels by meso-scale discovery-enzyme-linked immunosorbent assay, liquid chromatography-mass spectrometry, and immunofluorescence. The C5-12 promoter was highly selective for heart and skeletal muscles, when compared to off-target tissues such as peripheral blood mononuclear cells, lung, liver, and kidney. …”
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PTOV1 exerts pro-oncogenic role in colorectal cancer by modulating SQSTM1-mediated autophagic degradation of p53 by Yongli Fan, Yuqin Li, Xia Luo, Shiqi Xiang, Jia Hu, Jingchun Zhan, Weilong Chang, Rui Deng, Xianwen Ran, Yize Zhang, Yudie Cai, Weiwei Zhu, Huifen Wang, Zhibo Liu, Di Wang

“…Immunoprecipitation (IP) combined with protein mass spectrometry and Co-Immunoprecipitation (Co-IP) was used to identify p53 interacting with PTOV1. …”
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2-Heptanone Produces Sensorial-Emotional Changes, Depending on Length of Exposure / La 2-heptanona produce cambios sensorio-emocionales, dependiendo del tiempo de exposición by Ana Gloria Gutiérrez-García, Carlos M. Contreras, María Remedios Mendoza-López

“…Gas chromatography/mass spectrometry indicated that urinary 2-heptanone content was increased approximately two-fold during pre-menstruation compared with the days around ovulation. …”
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Temporal changes in plasma and milk lipids in response to an esophageal bolus of rumen-protected fish oil in lactating Holstein dairy cows by J.E. Rico, V. Sáinz de la Maza-Escolà, N.D. Senevirathne, P. Deme, N.J. Haughey, R. Gervais, J.W. McFadden

“…Extracted plasma was analyzed for individual FA and phospholipid concentrations using gas chromatography and mass spectrometry. Separated milk fat was analyzed for individual milk FA using gas–liquid chromatography and a flame-ionization detector. …”
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Salvia deserti Decne., an endemic and rare subshrub from Arabian desert: antidiabetic and antihyperlipidemic effects of leaf hydroethanolic extracts by Arbi Guetat, Slimen Selmi, Abdelrhman T. Abdelwahab, Marwa A. Abdelfattah, Abd Ealrhman M. Elhaj, Roaa T. Mogharbel, M. J. A. Abualreish, Abdullah F. Alanazi, Karim Hosni, Naceur Mejri, Abdennacer Boulila

“…The identity of phenolic compounds of the hydroethanolic extract of S. deserti was conducted through HPLC-Electrospray Ionization-Mass Spectrometry (LC-ESI-MS) analyses.ResultsOral administration of hydroethanolic extract of S. deserti at 200 and 400 mg/kg for 14 days significantly decreased blood glucose and restored the hepatic and renal function by reducing the levels of ALT, AST, ALP, GGT, LDH, urea and creatinine. …”
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A multicenter, randomized, open label, two formulation, crossover bioequivalence trial of doxorubicin hydrochloride liposomal injection in Chinese patients with metastatic breast c... by Jingshu Wang, Xiuping Lai, Herui Yao, Hui Yang, Xiaolong Cao, Xiaochen Wang, Ying Wang, Weiqi Nian, Xiaodong Zheng, Qingxiu Mai, Anding Liu, Xiaozhi Lv, Xiaoying Bi, Junyi Chen, Junyan Wu, Suiwen Ye

“…Pharmacokinetic (PK) evaluation was conducted through the collection of blood samples, and the liquid chromatography tandem mass spectrometry (LC/MS/MS) method was leveraged to quantify plasma concentrations of both liposome-encapsulated doxorubicin and non-encapsulated doxorubicin in patients. …”
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Maternal neonicotinoid pesticide exposure impairs glucose metabolism by deteriorating brown fat thermogenesis by Wenwen Zhu, Jiali Fang, Chenbo Ji, Hong Zhong, Tianying Zhong, Xianwei Cui

“…Urinary concentrations of seven widely used NEOs were quantified using ultra-high performance liquid chromatography multiple reaction monitoring mass spectrometry (UHPLC-MRM-MS/MS). Correlation analysis revealed the associations between NEOs concentrations and glucose homeostasis parameters. …”
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Effect of rhGH treatment on lipidome and brown fat activity in prepuberal small for gestational age children: a pilot study by Lorena González, Carolina Gonzalez-Riano, Pablo Fernández-García, Rubén Cereijo, Aina Valls, Andrea Soria-Gondek, Nativitat Real, Belén Requena, Joan Bel-Comos, Patricia Corrales, David Jiménez-Pavón, Coral Barbas, Francesc Villarroya, David Sánchez-Infantes, Marta Murillo

“…Untargeted lipidomics analysis was performed using liquid chromatography-mass spectrometry (LC-MS), and serum biomarker levels were measured using ELISA assays. …”
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Evolution of aroma compounds in round soy sauce aroma type baijiu during aging and the effect of aging markers on the lasting aroma in finished glass by Shi-Yi Wang, Chen Li, Yu-Jie Li, Guang-Qian Liu, Zhen-Ming Lu, Li-Juan Chai, Hong-Yu Xu, Jin-Song Shi, Song-Tao Wang, Cai-Hong Shen, Xiao-Juan Zhang, Zheng-Hong Xu

“…The round 1–4 SSABs were analyzed by gas chromatography–mass spectrometry and an electronic tongue over one-year aging. …”
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