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381
The Juno mission as a probe of long-range new physics
Published 2025-01-01“…Requiring that the contribution from the fifth force does not exceed the uncertainty of the precession shift inferred from data, we find that a new parameter space with the mass of the fifth-force mediator around 10−14 eV is excluded at 95% C.L.…”
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382
Irritable Bowel and Bacterial Overgrowth Syndromes: a Bacterial Link Hypothesis of Functional Disease
Published 2021-04-01“…Proinflammatory cytokines and mediators in SIBO, in turn, provoke visceral hypersensitivity and intense motility, the key IBS factors. …”
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383
STAT signaling in the pathogenesis and therapy of acute myeloid leukemia and myelodysplastic syndromes
Published 2025-03-01“…Aberrant activation of STAT proteins has been implicated as a mediator of oncogenesis in several malignancies. In this review, we discuss the role of STAT proteins in both regulated and dysregulated hematopoiesis, the consequences of dysregulation in acute myeloid leukemia and myelodysplastic syndromes, therapeutic strategies, and recent advancements in STAT-targeted therapy. …”
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384
Protocols for the application of human embryonic stem cell-derived neurons for aging modeling and gene manipulation
Published 2025-03-01“…Here, we present a protocol for applying human embryonic stem cell (hESC)-derived neurons to model aging and the further application of small interfering RNA (siRNA)-mediated gene silencing for functional investigations. …”
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385
Tomographic features of lung damage associate with D-Dimer levels and further clinical outcome in patients with acute respiratory distress syndrome due to COVID-19
Published 2025-02-01“…Likewise, lung injury has been related to activation of the coagulation-fibrinolysis systems and pro-inflammatory mediators; where D-Dimer acquires prognostic relevance. …”
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386
GDF15 induces immunosuppression via CD48 on regulatory T cells in hepatocellular carcinoma
Published 2021-09-01“…Regulatory T (Treg) cells are key mediators of HCC-associated immunosuppression. We investigated the selective mechanism exploited by HCC that lead to Treg cells expansion and to find more efficacious immunotherapies.Methods We used matched tumor tissues and blood samples from 150 patients with HCC to identify key factors of Treg cells expansion. …”
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387
Telomerase inhibiting phytochemicals derived from Blumea eriantha for cancer treatment: A comprehensive computational analysis
Published 2025-02-01“…The phytochemical also exhibited a robust binding affinity mediated by consistent magnesium metal ion interactions involving key residues such as Asp251, Asp252, Ile252, and Asp343, along with additional hydrogen bonding and water-mediated contacts that enhance its stability and selectivity. …”
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388
Deciphering Regulatory Networks Governing Seedling Emergence in Deep-Sown Direct-Seeded Rice Cultivation
Published 2025-02-01“…Additionally, a role for miRNA-mediated regulation of auxin response factors was hypothesized in seedling emergence regulation. …”
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389
The Foreign Commission of the Soviet Writers’ Union in 1950s-1960s: Boundaries, Obstacles, Tricks, Embarrassment, Impact
Published 2025-02-01“… In the 1950s and 1960s, the Foreign Commission of the Soviet Writers’ Union occupied the niche of mediator in relations between Western literature and the USSR. …”
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390
Towards a "literary" translation of the Scriptures: with special reference to a "poetic" rendition
Published 2002-06-01“… This study proposes a more dynamic, or “mediated,” approach to Bible translation as one possible option (among many), should this be called for by the contextual circumstances of the target language setting. …”
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391
THE CONCEPT OF “THE HOLY SEED” AS A COPING STRATEGY IN EZRA-NEHEMIAH AND ITS IMPLICATIONS FOR SOUTH AFRICA
Published 2018-06-01“…One of her basic assumptions is that coping plays a key mediating role in the reintegration process. Taking cue from her deliberation, this article aims to investigate the role played by psychological coping in the return of Judean exiles from Babylon in Ezra-Nehemiah. …”
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392
Rekonstrukcja przejawów e-kultury dziecięcej generowanej w cyfrowej przestrzeni bycia razem. Doniesienie z badań netnograficznych
Published 2020-11-01“…This includes an absence of temporal and spatial boundaries of children’s culture, the mediated nature of its members’ contacts, the involvement of children in the network, the existence of culture in external memory, the electronic character of culture creations and their ephemeral and peculiar nature. …”
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393
Prevalence of Oral Lesions Biopsies Among Different Laboratories
Published 2024-12-01“…. %) cases, cystic lesions were 49 (16.7%) cases, and immunologically mediated lesions were only 3.8%. Conclusions: The results showed a high frequency of malignant tumors, which need more evaluation of etiological factors. …”
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394
Children’s literature as coupling point between global sustainability concerns and children’s local agency
Published 2025-02-01“…The analyses show how children’s potential agency is developed through a dialectical process of becoming based on a sociocultural and phenomenological understanding of artefacts, mediating means and place as an event. …”
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395
Unveiling the wonders of bacteria-derived extracellular vesicles: From fundamental functions to beneficial applications
Published 2025-02-01“…Extracellular vesicles (EVs), are critical mediators of intercellular communication and exhibit significant potential across various biomedical domains. …”
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396
A new perspective on apoptosis: Its impact on meat and organoleptic quality in different animals
Published 2025-01-01“…To effectively improve and control meat quality across different animal species, it is important to gather more information on the mechanisms by which apoptotic potential, mediated through the interaction of apoptosis-related molecules, influences meat quality variations. …”
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397
Bidirectional regulation of reactive oxygen species for radiosensitization in nasopharyngeal carcinoma
Published 2025-02-01“…This radiosensitizer not only effectively reverses tumor hypoxia to promote reactive oxygen species (ROS) generation but also significantly inhibits glutathione (GSH)-mediated ROS scavenging, thereby achieving bidirectional radiosensitization by enhancing ROS production and suppressing its scavenging. …”
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398
Hormone Receptors in Cervicovaginal Cells
Published 2013-04-01“…The steroid hormones mediate their effects via intracellular reseptors (3P). …”
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399
Proton-electron coupling and mixed conductivity in a hydrogen-bonded coordination polymer
Published 2025-02-01“…We demonstrate the practical implications of this mechanism by examining the humidity-dependent synaptic plasticity of Ni-BAND, showcasing how MPECs can expand into traditional MIEC applications while leveraging their unique proton-mediated advantages.…”
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400
Exosome-like nanovesicles derived from kale juice enhance collagen production by downregulating Smad7 in human skin fibroblasts
Published 2025-02-01“…Plant-derived exosome-like nanovesicles (ELNs) are critical mediators of cross-kingdom communication, modulating gene expression in animal cells despite their plant origin. …”
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