New options for targeting TRPV1 receptors for cancer treatment: odorous Chinese herbal medicine by Minghui Zhang, Minghui Zhang, Zongao Wang, Zongao Wang, Shaojun Liu, Shaojun Liu, Yuxuan Li, Yuxuan Li, Yanting Gong, Yanting Gong, Min Liu, Min Liu

“…In this paper, we review the expression and significance of TRPV1 receptor in various cancer cell types, the role of TRPV1 in the apoptosis-proliferation balance, cancer cell invasion and metastasis, and tumor micro-environment, with emphasis on the mechanisms by which TRPV1 receptor mediates inflammatory response, immune system, and thus regulates cancer. …”
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Impact of community‑based health insurance on utilisation of preventive health services in rural Uganda: a propensity score matching approach by Emmanuel, Nshakira-Rukundo, Essa, Mussa Chanie, Nathan, Nshakira, Joachim, von Braun

“…We postulate that these findings are partly mediated by information diffusion and social networks, financial protection, which gives households the capacity to save and use service more, especially curative services that are delivered alongside preventive services. …”
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Hypothermia regulates mitophagy and apoptosis via PINK1/Parkin-VDAC 3 signaling pathway during oxygen-glucose deprivation/recovery injury by Luying Zhang, Song Yang, Hao Cui, Chenchen Hang, Xingsheng Wang, Le An, Zhenyu Shan, Zhen Liang, Rui Shao, Ziren Tang

“…Previous study has demonstrated that hypothermia provides neuroprotection via increasing PINK1/Parkin-mediated mitophagy. However, whether hypothermia can regulate both apoptosis and mitophagy through the PINK1/Parkin-VDAC3 signaling pathway or not. …”
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Relationship between programmed cell death and targeted therapy for thyroid cancer in patients with a poor prognosis: an update by Yuejia Zhao, Simeng Zhao, Zhe Fan, Yongfu Zhao, Guangzhi Wang

“…Programmed cell death (PCD) is a cell death process mediated by specific molecular program, regulated by specific genes within the cell. …”
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Study of charged Lepton Flavor Violation in electron muon interactions by Ran Ding, Jingshu Li, Meng Lu, Zhengyun You, Zijian Wang, Qiang Li

“…We investigate the possible charged Lepton Flavor Violation (cLFV) processes mediated by an extra massive neutral gauge boson Z′ in electron muon interactions, either at a proposed electron muon collider or in a fixed target experiment with high-energy muon beam hitting electrons in the target. …”
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Mechanisms and therapeutic potential of the hedgehog signaling pathway in cancer by Ge Cong, Xingyu Zhu, Xin Ru Chen, Hao Chen, Wei Chong

“…The hedgehog signaling pathway, a critical mediator in the normal development of numerous organs and the pathogenesis of cancer, is typically quiescent but is aberrantly activated in several malignancies. …”
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Virus-inspired biogenic delivery system for advancing cancer therapy by Di Sun, Hao Liang, Qianwen Mu, Chengchao Chu, Gang Liu, Chao Liu

“…In vaccine research, Virus-mimic nanovesicles have been effectively verified against cancer via the immunogenicity and the pharmacological effect of drug molecules delivered to mediate an immune response in the body. This review summarizes the research status of virus-inspired drug delivery platforms for cancer therapy utilization.…”
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Oral lichen planus involving the palate: Case report and review of literature by Shahen Ali Ahmed, Ali Fakhree Alzubaidee

“…Women are most often affected and lichen planus is usually reported in individuals over 50 years of age The etiology of lichen planus is unknown at present and the disorder has been classified as a chronic disease of immune-mediated pathogenesis. The oral lesions are usually bilateral and involve the buccal mucosa in about 90 percent of all cases. …”
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Probing exotic long-lived particles from the prompt side using the CONTUR method by L. Corpe, A. Goudelis, S. Jeannot, S. Jeon

“…The probed models include feebly-interacting dark matter, hidden sector models mediated by a heavy neutral scalar, dark photon models and a model featuring photo-phobic axion-like particles.…”
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Blue light promotes conjunctival epithelial-mesenchymal transition and collagen deposition through ITGB4 by Qianjie Yang, Kuangqi Chen, Siyi Chen, Yinhao Wang, Yutong Xia, Jinbo Chen, Ye Shen

“…Reactive oxygen species-mediated damage caused by BL upregulated ITGB4 expression, promoting cell migration and EMT through the extracellular signal-regulated kinase /Snail pathway.…”
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In vivo regulation of the monocyte phenotype by Mycobacterium marinum and the ESX-1 type VII secretion system by Kristina Munke, Line Wulff, Julia Lienard, Fredric Carlsson, William W. Agace

“…Our findings demonstrate that infection of infiltrating monocytes with M. marinum alters their cytokine expression profile, induces glycolytic metabolism, hypoxia-mediated signaling, nitric oxide synthesis, tissue remodeling, and suppresses responsiveness to IFNγ. …”
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Eosinophilic esophagitis: literature review and original case presentation by V. T. Ivashkin, Ye. K. Baranskaya, V. O. Kaybysheva, Ye. V. Ivanova, Ye. D. Fedorov

“…Eosinophilic esophagitis is chronic immune antigen-mediated inflammatory disease of the esophagus with still obscure etiopathogenesis. …”
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The regulatory role of placental extracellular vesicle on trophoblast and endothelial cell functions by Kunfeng Bai, Kunfeng Bai, Xintong Li, Yanjie Guo, Ye Shang, Leqian Lin, Philip C. N. Chiu, Philip C. N. Chiu, Cheuk-Lun Lee

“…During pregnancy, EVs are secreted by the syncytiotrophoblast layer of the placenta villi, where they mediate the functions of resident leukocytes and invading extravillous trophoblasts (EVTs) in the decidua. …”
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Follistatin like-1 aggravates silica-induced mouse lung injury by Yinshan Fang, Si Zhang, Xiaohe Li, Fangxin Jiang, Qiao Ye, Wen Ning

“…The induced Fstl1 regulated inflammation response via activation of nod-like receptor family, pyrin domain containing 3v (NLRP3) inflammasome-mediated IL-1β production from macrophages. Meanwhile, Fstl1 promoted fibrosis via positive regulation of TGF-β1 signaling. …”
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Czy pojawienie się technologii informacyjno-komunikacyjnych w klasie szkolnej oznacza zmianę praktyk nauczania i uczenia się? by Lucyna Kopciewicz

“…The analysis resulted in three distinct sets of emergent teaching and learning practices and a series of conflicts and tensions teachers experience in their everyday tablet-mediated teaching practices. …”
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Feminist spiritualities, gender equality and sustainable development: The possibilities of a countermovement by N. Swanepoel, T. van Wyk

“…Feminist spirituality became a countermovement – countering perceptions and ingrained convictions that a woman could not be a mediator between God and humanity. Feminist spirituality contributed to the creation of spaces for women to study and participate in the creation of religious-spiritual texts. …”
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Remote cooling of spin-ensembles through a spin-mechanical hybrid interface by Yang Wang, Durga Bhaktavatsala Rao Dasari, Jörg Wrachtrup

“…Abstract We present a protocol for the ground-state cooling of a tripartite hybrid quantum system, in which a macroscopic oscillator acts as a mediator between a single-probe spin and a remote spin ensemble. …”
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Desmoplastic reaction in the microenvironment of head and neck and other solid tumors: the therapeutic barrier by Kohei Okuyama, Maiko Tsuchiya, Kala Chand Debnath, Shajedul Islam, Souichi Yanamoto

“…DR promotes epithelial-mesenchymal transition and cancer cell invasion through CAF-mediated extracellular matrix remodeling and signaling pathways such as transforming growth factor-beta. …”
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