Health care utilization patterns of patients enrolled in an interdisciplinary program for back pain by Sara Davin, Psy.D., MPH, Brittany Lapin, PhD., MPH, Belinda Udeh, PhD, Sarah Rispinto, PhD, Nicolas R. Thompson, MS, Ryan Honomichl, PhD, Andre Machado, MD, Irene L. Katzan, MD

“…Healthcare utilization categories included outpatient resources, specialist visits, imaging, pain interventional procedures, and acute care utilization. Opioid use was also extracted based on inpatient and outpatient orders, as well as days on opioids within 2 weeks following an emergency department visit or hospitalization. …”
Get full text

Potential improvement in spatial accessibility of methadone treatment with integration into other outpatient substance use disorder treatment programs, New York City, 2024. by Marcus A Bachhuber, Chinazo O Cunningham, Ashly E Jordan

“…<h4>Background</h4>Methadone is an effective treatment for opioid use disorder; however, its provision in the US is limited to federally-regulated opioid treatment programs (OTP). …”
Get full text

Postoperative Pain and Opiate Requirement is Increased Following Second-Side Surgery Among Patients Undergoing Staged Total Knee Arthroplasty by Vivek P. Chadayammuri, MD, Shuvalaxmi D. Haselton, MS, Elizabeth Diaz, PA-C, Roger H. Emerson, MD

“…Patients with a history of chronic opioid dependency were excluded. Baseline demographics, primary outcome measures, including visual analog scale (VAS) pain scores, perioperative opioid utilization (MME/day), and surgical satisfaction were evaluated. …”
Get full text

Global cervical cancer elimination: quantifying the status, progress, and gaps by Liangru Zhou, Yi Li, Hongyun Wang, Ruixi Qin, Zhen Han, Ruifeng Li

“…The 10 countries with the highest annual opioid consumption (excluding methadone) for CC, in oral morphine equivalence per capita (2017), were all HICs. …”
Get full text

Cost analysis of MOUD implementation and sustainability in Massachusetts jails by Danielle Ryan, Don Lochana Ekanayake, Elizabeth Evans, Edmond Hayes, Thomas Senst, Peter D. Friedmann, Kathryn E. McCollister, Sean M. Murphy

“…Abstract Background In 2018 Massachusetts mandated that county jails offer all FDA-approved medications for opioid use disorder (MOUD) to incarcerated individuals with OUD. …”
Get full text

Magnesium in pain control - mechanisms of action in perioperative pain, neuropathic pain and migraine by Anna Konarska, Artur Fabijański, Adriana Dukacz, Wojciech Firlej, Joanna Rychlewska-Duda, Justyna Lisiecka, Michał Nowak, Mateusz Janik, Barbara Ufnalska, Anna Machowiak

“…Evidence suggests that magnesium supplementation can reduce opioid use, counteract central and peripheral sensitization, and potentially prevent migraine attacks, highlighting its potential as an effective adjuvant in pain management strategies. …”
Get full text

Substance Abuse: A Public Health Concern by Ulfat Amin, Adil Mudasir Malla, Ishrat Amin, Roohi Jan

“…Cannabis, sedatives, hypnotics, anxiolytics, inhalants, opioids, hallucinogens, and stimulants are the most abused drugs. …”
Get full text

Evaluation of the functional gastrointestinal diseases concept from standpoints of Rome IV (2016) diagnostic criteria (review) by D. N. Andreyev, A. V. Zaborovsky, A. S. Trukhmanov, I. V. Mayev, V. T. Ivashkin

“…The new nosological entities with known causative factor (opioid-induced gastrointestinal hyperalgesia, opioidinduced constipation, cannabinoid induced hyperemesis syndrome), hypersensitive reflux syndrome, nausea and vomiting syndrome (that encompasses previously separate nosological forms: chronic idiopathic nausea and functional vomiting) were added to the new version of the classification. …”
Get full text

Pathogenesis of Functional Biliary Pain and Pharmacology of Trimebutin by E. L. Bueverova, O. Yu. Zolnikova, N. L. Dzhakhaya, A. V. Sedova, V. Т. Ivashkin

“…In the multilevel system of regulation of the gallbladder and sphincter apparatus, the opioid system occupies a special place. The agonist of peripheral receptors of the enkephalinergic system, trimebutine, in clinical studies led to the relief of biliary pain in more than 80 % of patients with functional biliary disorders, while a significant decrease in the severity of diarrhea, dyspeptic, and constipation syndromes was revealed.Conclusion. …”
Get full text

Possible erythropoietin pharmacotherapeutic targets on painful diabetic neuropathy in rats by SAMUEL SUAREZ-MENDEZ, DEYSI Y. BERMÚDEZ-OCAÑA

“….), methiothepin (non-selective 5-HT receptor antagonist; 0.01-0.1 mg/kg, i.p.) and naloxone (non-selective opioid receptor antagonist; 1 mg/kg). Intraperitoneal administration of erythropoietin (500-4000 UI/kg) prevented allodynia in diabetic rats. …”
Get full text

Comparison of Real-world Outcomes Between Patients Treated with Tapentadol ER or Oxycodone CR by Mike Durkin, Jacqueline Pesa, Jessica Lopatto, Rachel Halpern, Damon Van Voorhis, Stephanie Korrer

“…**Background:** The objective of this study was to compare health care utilization and costs between matched cohorts of chronic pain patients treated with the opioids tapentadol extended release (ER) or oxycodone controlled release (CR). …”
Get full text

Diagnosis and treatment of the irritable bowel syndrome: clinical guidelines of the Russian gastroenterological association and Russian association of coloproctology by V. T. Ivashkin, Yu. A. Shelygin, Ye. K. Baranskaya, Ye. A. Belousova, A. G. Beniashvili, S. V. Vasilyev, A. O. Golovenko, O. V. Golovenko, Ye. G. Grigoryev, N. V. Kostenko, T. L. Lapina, I. D. Loranskaya, O. S. Lyashenko, I. V. Mayev, Ye. A. Poluektova, V. G. Rumyantsev, V. M. Timerbulatov, A. S. Trukhmanov, O. Yu. Fomenko, I. L. Khalif, E. Yu. Chashkova, A. A. Sheptulin, O. S. Shifrin, V. V. Yanovoy

“…Enterokinetic agent prucalopride may be prescribed at inefficacy of laxatives. Peripheral opioid agonists (trimebutine maleate) normalizing intestinal motor activity via action on different subtypes of peripheral opioid receptors, combined plant-derived medication STW 5 are applied as well. …”
Get full text

Functional constipation by Yu. O. Shulpekova, A. A. Kurbatova, A. V. Sedova

“…In the section devoted to the bowel diseases the new entity - opioid-induced constipation was defined; besides that diagnostic (mostly - the time-based criteria) of irritable bowel syndrome and functional constipation were modified. …”
Get full text

Unmet needs in the management of migraine in Greece from the perspective of medical experts: a Delphi consensus by Georgia Kourlaba, Michail Vikelis, Theodoros Karapanayiotides, Argyro Solakidi, Dimitrios Trafalis, Katerina Lioliou, Panagiotis Andriopoulos, Aspasia Panagiotou, Dimos-Dimitrios Mitsikostas

“…However, consensus was not reached on statements concerning patient preferences for treatment administration, treatment adherence, opioid use, and frequency of visits to neurologists. …”
Get full text

Economic Outcomes and Incidence of Postsurgical Hypotension With Liposomal Bupivacaine vs Epidural Analgesia in Abdominal Surgeries by Margaret Holtz, Nick Liao, Jennifer H. Lin, Carl V. Asche

“…**Background:** Epidural analgesia can be associated with high costs and postsurgical risks such as hypotension, despite its widespread use and value in providing opioid-sparing pain management. We tested the hypothesis that liposomal bupivacaine (LB) might be a reliable alternative to epidural analgesia in this real-world study. …”
Get full text

Staphylococcus aureus susceptibilities from wounds of patients who use illicit fentanyl by Drew T. Dickinson, Stephen Saw, Lauren Dutcher, Christina Maguire, Adrienne Terico, Margaret Lowenstein, Sonal Patel

“…We compared frequency of in-hospital medication treatment for opioid use disorder among patients who left the hospital prior to vs after the availability of S. aureus susceptibilities. …”
Get full text

Peer-assisted telemedicine hepatitis-C treatment for people who use drugs in rural communities: a mixed methods study by Kim Hoffman, Gillian Leichtling, Sarah Shin, Andrew Seaman, Tonhi Gailey, Hunter C. Spencer, P. Todd Korthuis

“…Abstract Background The increase in opioid use disorder among young, nonurban people has fueled sharp rises in hepatitis C virus (HCV) infections. …”
Get full text

Acute fibrinous and organizing pneumonia after lung transplantation: A case report of treatment with infliximab and tocilizumab and literature review by Christophe Abellan, Foteini Ioakeim, Alessio Casutt, Benoit Lechartier, Zisis Balmpouzis, Samuel Rotman, Leslie Noirez, Isabelle Rochat, John-David Aubert, Angela Koutsokera

“…She developed severe pleuritic pain needing opioid treatment and died 4 months later. Conclusion: While high-dose systemic corticosteroids remain the first line of treatment, the use of anti TNF-α has shown promising results in case reports. …”
Get full text

Study protocol of a pilot randomised controlled trial assessing the feasibility and acceptability of RecoverEsupport: a digital health intervention to enhance recovery in women und... by Christopher Oldmeadow, Mitch J Duncan, Penny Reeves, Priscilla Viana da Silva, Rebecca Wyse, Helen Moore, Alison Zucca, Sancha Robinson, Stephen Ridley Smith, Emma Sansalone, Owen Morris, Rebecca Chenery, Lara Riley, Anna Palazzi-Parsons

“…Enhanced Recovery After Surgery (ERAS) guidelines include the following patient-managed recommendations: early mobilisation, early eating and drinking, opioid minimisation and physiotherapy exercises. Low adherence rates to these recommendations suggest that patients need support to do these things. …”
Get full text

A longitudinal cohort study on dispensed analgesic and psychotropic medications in older adults before, during, and after the COVID-19 pandemic: the HUNT study by Tanja Louise Ibsen, Ekaterina Zotcheva, Sverre Bergh, Debby Gerritsen, Gill Livingston, Hilde Lurås, Svenn-Erik Mamelund, Anne Marie Mork Rokstad, Bjørn Heine Strand, Richard C. Oude Voshaar, Geir Selbæk

“…Results Overall, prescriptions of opioids, other analgesics, and anxiolytics/sedatives were higher in 2022 than during the lockdown. …”
Get full text