Clinical and Cost Burden of Primary Sjögren’s Syndrome: Descriptive Analysis Using a US Administrative Claims Database by Sue Perera, Liyuan Ma, Raj Punwaney, Sulabha Ramachandran

“…These patients experienced a higher disease burden, and more commonly reported pain, fatigue or insomnia and any combination of pain, fatigue or insomnia (41.3%) compared with patients with glandular disease only (12.4%). …”
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Extracecellulr vesicles (EVs) microRNAs (miRNAs) derived from mesenchymal stem cells (MSCs) in osteoarthritis (OA); detailed role in pathogenesis and possible therapeutics by Seyede Sara Pakdaman Kolour, Saeide Nematollahi, Masoud Dehbozorgi, Farnaz Fattahi, Fatemeh Movahed, Neda Esfandiari, Mohammad Saeed Kahrizi, Nima Ghavamikia, Bahareh Salmanian Hajiagha

“…The primary cause of pain and disability in the world is osteoarthritis (OA), a common joint disease characterized by the primary pathological alteration in articular cartilage deterioration. …”
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Hymecromone Efficacy in the Treatment of Biliary Pancreatitis by A. V. Okhlobystin, M. A. Tatarkina, O. Z. Okhlobystina, S. A. Budzinskiy, P. V. Pavlov, L. A. Labut

“…According to factor analysis, monotherapy with hymocromone resulted in a decrease in abdominal pain, nausea, heaviness in the abdomen and bloating. …”
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An Unusual Case of Primary Aneurysmal Bone Cyst of the Patella with a Review of Literature by Girish Mugdum, Rajiv Kaul, Anil Kumar Mishra

“…A 28-year-old male, who presented with intermittent knee pain of 9 months duration, with swelling and tenderness over the patella underwent a clinico-radiological evaluation which revealed fluid-fluid levels, suggestive of an aneurysmal bone cyst (ABC). …”
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Successful rivaroxaban and doxycycline therapy for Mycoplasma pneumonia with pulmonary embolism in children: a case report by Fang Xiaoqian, Lu Hemin

“…A 10-year-old male presented with fever, cough, and chest pain as the main symptoms. M pneumoniae polymerase chain reaction of bronchoalveolar lavage fluid was positive, and computed tomography angiography indicated pulmonary embolism. …”
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Modern approaches to functional dyspepsia treatment by A. A. Sheptulin

“…At a choice of specific drug clinical variant of disease should be taken into account. At pain-predominant (ulcer-like) variant antisecretory agents (first of all — proton pump inhibitors) are the drugs of choice, at postprandial distress syndrome (dysmotility-like variant) - prokinetics. …”
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Metateoretiese perspektiewe op liggaamlike probleme as moontlike uitvloeisel van onverwerkte trauma by W. Coetzer, H. Kotzé

“…For most persons, the initial response to trauma is that of denial. However, emotional pain that is suppressed on a continued basis could result in physical problems. …”
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Clinical Guidelines of the Russian Society of Surgeons, the Russian Gastroenterological Association, the Association of Surgeons-Hepatologists and the Endoscopic Society “REndO” o... by V. T. Ivashkin, A. G. Kriger, A. V. Okhlobystin, M. A. Anischenko, S. S. Kardasheva, S. A. Alekseenko, S. F. Bagnenko, M. I. Bykov, S. A. Budzinskiy, I.  M. Buriev, V. A. Vishnevskiy, E. I. Galperin, V. P. Glabay, V. R. Goltsov, T. G. Dyuzheva, G. G. Karmazanovskiy, M. P. Korolev, D. M. Krasilnikov, Yu. A. Kucheryavy, I. V. Maev, N. A. Maystrenko, M. F. Osipenko, M. I. Prudkov, V. I. Simanenkov, E. G. Solonitsin, A. V. Fedorov, E. D. Fedorov, I. B. Khlynov, M. V. Chikunova, A. V. Shabunin, S. G. Shapovalyants, A. A. Sheptulin, O. S. Shifrin

“…Aim: to present modern methods of diagnosis and treatment of chronic pancreatitis for gastroenterologists, general practitioners and physicians.Chronic pancreatitis (CP) is a long-term inflammatory disease of the pancreas, manifested by irreversible morphological changes in the parenchyma and pancreatic ducts, which cause pain and/or persistent impairment of function. Current concept on the etiology of CP is reflected by the TIGAR-O classification. …”
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Russian Non-Interventional Study of the Efficacy and Tolerability of Rifaximin-α Therapy in Patients with Uncomplicated Diverticular Disease under the Conditions of Outpatient Prac... by O. S. Shifrin, E. A. Poluektova, A. V. Korolev, T. I. Semenova, M. V. Shein, G. N. Leksikova, O. A. Tokareva, O. E. Davydova, P. S. Andreev, S. E. Katorkin, A. A. Chernov, A. V. Zhuravlev, O. S. Sek, A. A. Kopina, N. Yu. Samokhina, Yu. V. Gorozhankina, M. F. Samigullin, V. S. Groshilin, E. N. Borisova, T. A. Petrova, I. Yu. Pirogova, S. V. Mednikov, N. V. Smagin, A. S. Sarsenbaeva, N. V. Smirnova, L. G. Kirsanova, N. M. Malyutina, M. A. Smirnova, E. N. Shleikova, V. T. Ivashkin

“…Such symptoms, as abdominal pain, constipation, diarrhea, flatulence and tenesmus were evaluated using a 4-score scale. …”
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Management of Complex Nonunion of Long Bones by Distraction Osteogenesis Using Monorail Fixator by Azad Khan, Parwez Ahmed, Vishvendra Tomar, Rahul Kumar Gupta, Areeb Ali Siddiqui, Mohd Adnan

“…Other complications encountered were pain during distraction, pin loosening, and joint stiffness. …”
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Disorders of esophageal clearance in gastroesophageal reflux disease and option of their treatment by O. A. Storonova, A. S. Trukhmanov, N. L. Dzhahaya, V. T. Ivashkin

“…Overall 30 patients whose symptoms included heartburn (100%), burning chest pain (70%), belching (30%) were enrolled in original study. …”
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Clinical advances in kidney autotransplantation: a review by Shengjie Lin, Jingci Gai, Shangjin Huang, Yingzhen He, Da Hao, Shuhang Luo, Yilong Lin, Jiang Qiu, Jun Li, Changxi Wang, Chenglin Wu

“…Kidney autotransplantation may be indicated for the rare condition of loin pain-hematuria syndrome when conservative measures fail. …”
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Torque visuomotor feedback training versus standard eccentric exercise for the management of patellar tendinopathy: protocol for a randomised controlled trial by David Evans, Francesco Negro, Michail Arvanitidis, Eduardo Martinez-Valdes, Ragul Selvamoorthy, Patricio Pincheira

“…Our primary objective is to evaluate whether the TF protocol reduces pain and disability more effectively than the EE protocol in individuals with PT. …”
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Experience of Two-Stage Treatment of Rectal Fistulas Using Low-Thrombin Fibrin Glue “Kriofit” by S. А. Frolov, A. M. Kuzminov, D. V. Vyshegorodtsev, V. Yu. Korolik, I. S. Bogormistrov, A. N. Ryndin

“…In the postoperative period, the intensity of pain syndrome was assessed using the visual analog scale of pain. …”
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A clinical study on the efficacy and safety of poly-herbal formulation in managing functional dyspepsia by Debasish Hota, Anand Srinivasan, Manas Kumar Panigrahi, Snigdha Suman Dalua, Poorva Tiwari, Ramachandran Valavan

“…The burning feeling behind the breastbone, pain behind the breastbone, burning feeling in the center of the upper stomach, acid taste in the mouth, and unpleasant movement of material upwards towards the mouth improved significantly from the beginning of the study to the follow-up visits. …”
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Dimensions of suffering and the need for palliative care: experiences and expectations of patients living with cancer and diabetes and their caregivers in Mexico – a qualitative st... by Svetlana V Doubova, Ingrid Patricia Martinez-Vega, Felicia Knaul, Afsan Bhadelia, Diana Pérez-Moran, Nancy García-Cervantes

“…They expressed the importance of relief from suffering, viewing it as the health sector’s responsibility and requesting more humane, personalised care and access to medicines and pain clinics.Conclusions The multifaceted nature of SHS highlights the health system’s responsibility to provide high-quality palliative care. …”
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A Rare Case of Spontaneous Heterotopic Pregnancy at 12 weeks of Gestation Following Natural Conception With Literature Review by Wang F, Xu Y, Dong X, Jiang P, Yu QQ

“…Lower quadrant abdominal or pelvic pain should prompt consideration of heterotopic pregnancy, as the presence of an intrauterine pregnancy does not exclude a concurrent ectopic pregnancy.Keywords: ectopic pregnancy, heterotopic pregnancy, laparoscopy, spontaneous pregnancy…”
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Effects of manual osteopathic interventions on psychometric and psychophysiological indicators of anxiety, depression and stress in adults: a systematic review and meta-analysis of... by Darren J Edwards, Jerry Draper-Rodi, Danny Miller, Josh Hope-Bell, Andrew MacMillan, Tom C Gordon

“…Depression improvements were greater in pain populations (Hedges’ g=−0.61, 95% CI: –1.06 to –0.17, p=0.01). …”
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Protocol of a randomised trial of teriparatide followed by zoledronic acid to reduce fracture risk in adults with osteogenesis imperfecta by Jennifer Walsh, Catriona Keerie, Stuart H Ralston, Christopher J Weir, Muhammad K Javaid, WAYNE LAM, Bente L Langdahl, Jannie D Hald, Patricia Osborne

“…Questionnaires will be completed to assess pain and other aspects of health-related quality of life (HRQoL). …”
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