Phytochemical profile, therapeutic potentials, nutritional composition, and food applications of ginger: a comprehensive review by Great Iruoghene Edo, Ufuoma Augustina Igbuku, Raghda S. Makia, Endurance Fegor Isoje, Tayser Sumer Gaaz, Emad Yousif, Agatha Ngukuran Jikah, Khalid Zainulabdeen, Patrick Othuke Akpoghelie, Rapheal Ajiri Opiti, Arthur Efeoghene Athan Essaghah, Dina S. Ahmed, Huzaifa Umar

“…Ginger exerts its bioactivities via a number of mechanisms such as inhibiting the activation of tumor necrosis factor α and cyclooxygenase-2 in human synoviocytes and limiting the body’s leukotrienes and prostaglandins to elicit anti-inflammatory activity, activating the descendent inhibitory pathways of pain and suppressing the transmission of nociceptive signals thus exhibiting anti-nociceptive effects amongst others. …”
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Osteoperiosteal versus osteochondral for autologous transplantation in the treatment of large cystic osteochondral lesions of the talus by Lequan Liu, Jiangtao Jin, Jinping Pan, Huikang Guo, Sen Li, Jisheng Li, Zheng Zhang

“…Results The within-group comparison showed significant improvements in pain severity and function in both groups post-treatment compared with pre-treatment. …”
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Combination of Gilbert's syndrome and gastrointestinal diseases by G. M. Dubrovina, O. K. Botvinyev, A. I. Kolotilina

“…Patients demonstrate various complaints related to disorders — nausea, decrease of appetite, heartburn, epigastric pain, defecation disorders. Gilbert's syndrome quite often is combined to of the upper gastro-intestinal diseases (gastroduodenitis, esophagitis, sphincter disorders). …”
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Liver cystic echinococcosis: A retrospective study on the demographics and clinical profile of patients managed at a single tertiary institution in central Eastern Cape Province, S... by A Govindasamy, P R Bhattarai, J van Niekerk, J John

“…The mean age of the patients was 37.5 years. Abdominal pain (n=39; 69.6%) was the most common presenting symptom, and a palpable abdominal mass (n=36; 64.3%) was the predominant presenting sign. …”
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Effectiveness of supracondylar dome osteotomy in reducing lateral condylar prominence and enhancing functional outcomes in pediatric cubitus varus: a retrospective study by Yam Prakash Gurung, Sabin Pokharel, Rajan Bhusal, Tarun Rajbhandari, Ashok Kumar Banskota, Bibek Banskota

“…While primarily considered a cosmetic concern, it can lead to significant complications, including chronic pain, ulnar nerve palsy, and posterolateral elbow instability. …”
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The Fibularis Quartus Muscle: A Cadaveric Case Report with Historical, Embryological, Molecular and Clinical Considerations by Dibakar Borthakur, Rajesh Kumar, Namaschivayam G R, Mohammed Ahmed Ansari, Seema Singh

“…The muscle has been implicated in a variety of clinical problems ranging from ankle pain to subluxation and tear of peroneal tendons. …”
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Point of Care Ultrasound Guided Management of Lateral Ankle Sprains: A Case Series by Matthew Bush, Jon Umlauf, Bryan Pickens

“…Participants completed the Foot and Ankle Ability Measure (FAAM) activities of daily living and Sports subscale, the Foot and Ankle Outcome Score (FAOS), Patient Reported Outcomes Measurement Information Systems Global Health, Tampa Scale of Kinesiophobia (TSK-11), Cumberland Ankle Instability Tool (CAIT), and the Numeric Pain Rating Scale as well as the Ankle Lunge Test and Figure 8 measurements at baseline, 4 weeks, 8 weeks and 12 weeks post enrollment. …”
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Airway Management in Pan Facial Fracture: An Outcome Analysis of Elective Tracheostomy and Submental Endotracheal Intubation by Vipin Venugopal Nair, Yuvraj Issar, Harmanjot Singh Dhillon, Gurpinder Singh Ghotra, Pranay Pratap, Ayush Mathur, Kamalpreet Singh

“…Demographic data, intraoperative time (IOT), length of hospital stay (LOHS), postoperative pain score at three and seven days, and Vancouver Scar Score (VSS) at 4 and 12 weeks was compared between the two groups. …”
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Exploration of analgesic and anthelmintic activities of Artocarpus chaplasha ROXB. leaves supported by in silico molecular docking by S M Sohag, Sharmin Nur Toma, Md. Niaj Morshed, Md. Al Imran Imon, Md. Monirul Islam, Md. Ibnul Piash, Naznin Shahria, Imran Mahmud

“…Our present study suggests that Aartocarpus chaplasha leaves can be a potential source of lead compounds for pain management and helminth infections and further advanced investigations are required in the future.…”
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The Effects of Adverse Events and Associated Costs on Value-Based Care for Metastatic Pancreatic Ductal Adenocarcinoma by Prachi Bhatt, Jared Hirsch, Paul Cockrum, George Kim, Gabriela Dieguez

“…Rates of most nonhematologic AEs were higher in patients receiving FFX with all 4 components, with diarrhea occurring in 28.3%, abdominal pain in 31.5%, and nausea/vomiting in 41.5% of patients. …”
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Do We Need A Bone Block Procedure in Recurrent Anterior Shoulder Instability?: A Case Report by Hastomo Agung Wibowo, Dadang Rona Sasetyo, Yusa muhammad Thoriq, Felix Giovanni Hartono

“…The surgery was successfully performed, and there was no sign of recurrent instability and pain after one year. Discussion: The number of recurrent shoulder dislocations is over 75%. …”
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Economic Outcomes and Incidence of Postsurgical Hypotension With Liposomal Bupivacaine vs Epidural Analgesia in Abdominal Surgeries by Margaret Holtz, Nick Liao, Jennifer H. Lin, Carl V. Asche

“…**Background:** Epidural analgesia can be associated with high costs and postsurgical risks such as hypotension, despite its widespread use and value in providing opioid-sparing pain management. We tested the hypothesis that liposomal bupivacaine (LB) might be a reliable alternative to epidural analgesia in this real-world study. …”
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Endometrial Carcinoma Presenting with an Isolated Osseous Metastasis: A Case Report by Nesrine Tounsi, Ines Zemni, Fatma Saadalah, Maher Slimane, Nadia Boujelbene, Mohamed ali Ayadi, Chargui Rhiad, Rahal Khaled

“…She was complaining about progressive right rib pain as a first sign of the disease of endometrial cancer. …”
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A Clinical Study on Functional Outcome of Percutaneous Transforaminal Endoscopic Discectomy under Local Anesthesia by Suryansh Nema, Varun Kumar Agarwal

“…This study included 54 patients with radicular pain for at least 3 weeks with a positive nerve root compression sign and who underwent PTED under local anesthesia. …”
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Chiari malformation with concurrent papilledema: a patient-level meta-analysis of case reports and case series by Alejandro Pando, Daniel J. Valdivia, Daniel A. Brenner, Mohammed Ali Alvi, Hai Sun, James K. Liu, Ira Goldstein

“…Abstract Background Chiari I malformation, characterized by the displacement of cerebellar tonsils, and Chiari 1.5, involving cerebellar tonsils and brainstem displacement, share symptoms with Idiopathic Intracranial Hypertension, including headache, paresthesia, vision issues, shoulder/arm pain, diplopia, numbness, and motor weakness. Historically, papilledema marked IIH, but there are reports of papilledema in patients with Chiari I/1.5, leading to uncertainty about the most effective treatment strategies. …”
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Efficacy of osmotic laxative polyethylene glycol 4000 in treatment of constipation in pediatrics by S. I. Erdes, B. O. Matsukatova, S. A. Revyakina, Ye. V. Casanave

“…The symptoms testifying complication of disease, such as spastic abdominal pain (80%), flatulence (87%) and anal painfulness (73%) were revealed as well. …”
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Comparative Study of Diode Laser Versus Intense Pulsed Light (IPL) for the management of Hirsutism in Sulaimani Government by Burhan Tahir Saeed

“…The present study was carried out in order to compare diode laser and IPL procedures regarding their effectiveness in decreasing hirsutism, patient satisfaction, and pain level. The present cross-sectional prospective study was carried out on 66 patients with hirsutism who regularly visited a dermatology clinic in Sulaimani, Kurdistan Region-Iraq over a period of 8 months from February to October 2020. …”
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Clinical Recommendations of the Russian Gastroenterological Association on Diagnosis and Treatment of Infectious Esophagitis by V. T. Ivashkin, N. D. Yuschuk, I. V. Maev, A. S. Trukhmanov, O. A. Storonova, A. A. Makushina, S. S. Pirogov, O. V. Zayratyants, O. P. Alekseeva, D. N. Andreyev, T. L. Lapina, A. V. Tkachev, Yu. P. Uspenskiy, A. A. Sheptulin

“…However, cases of severe odynophagia, dysphagia, severe pain syndrome, high complication risks (e.g., esophageal ulcer bleeding in thrombocytopenia), severe immunodeficiency, generalised forms of disease and severe concomitant disorders are considered for hospital care. …”
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Ultrasonic characteristics of inserted central catheter related fibroblastic sleeve by Zhifei Ben, Jue Wang, Jinyong Zhan, Kaiying Xu

“…Patients required the ultrasound evaluation due to local swelling and pain, abnormal coagulation function, lack of response to flushing of saline and heparin, or before extubation. …”
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Surgical Treatment Patterns, Healthcare Resource Utilization, and Economic Burden in Patients with Tenosynovial Giant Cell Tumor Who Underwent Joint Surgery in the United States by Feng Lin, Winghan J. Kwong, Sherry Shi, Irina Pivneva, Eric Q. Wu, John A. Abraham

“…**Background:** Tenosynovial giant cell tumors (TGCT) are rare and locally aggressive neoplasms in synovium, bursae, and tendon sheaths, which cause pain, joint dysfunction, and damage to the affected joints. …”
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