Transcriptional regulation of suberin and its response to the environment by ZHOU Yue, AN Yongping, MA Rong, WANG Pei

“…Acting as a barrier between the plants and their environment, suberin controls the transport of water and solutes, protecting plants from environmental stresses and pathogenic invasion. This article reviews the key enzymes and transcription factors involved in suberin biosynthesis, and discusses the impact of environmental factors on suberin synthesis and deposition. …”
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Investigation of new exopolysaccharides produced by strains of donkey milk by Arevik Israyelyan, Tsovinar Balabekyan, Lara Aleksanyan, Inesa Sahakyan, Anna Gasparyan, Flora Тkhruni

“…Results: The antimicrobial activity of the polysaccharide and antimicrobial protein-like fractions of the genus Enterococcus strains depends on its concentration, time of interaction with the test culture, and the species of the pathogenic bacteria. Conclusion: The obtained results were shown that strains isolated from fermented donkey milk that are capable of synthesizing two substances of different nature with high antimicrobial properties during the growth process are promising for further research and application for their use as probiotics and biopreparations in pharmaceuticals. …”
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Integrating agent-based disease, mobility and wastewater models for the study of the spread of communicable diseases by Néstor DelaPaz-Ruíz, Ellen-Wien Augustijn, Mahdi Farnaghi, Sheheen A. Abdulkareem, Raul Zurita Milla

“…To that end, we developed an integrated Agent-Based Model (ABM) that facilitates analysis in space and time at various temporal resolutions, including disease spread, population mobility and wastewater production, while also being sufficiently generic for different types of infectious diseases or pathogens. The integrated model replicates the epidemic curve for COVID-19 and can estimate the daily infections at the household level, enabling the monitoring of the spatial patterns of infection intensity. …”
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Combating antibiotic resistance: mechanisms, challenges, and innovative approaches in antibacterial drug development by Aiswarya M. Rajesh, Shraddha Subhash Pawar, Kruthi Doriya, Rambabu Dandela

“…Key antibiotics discussed include carvacrol, dalbavancin, quinolones, fluoroquinolones, and zoliflodacin, each with unique actions against bacterial pathogens. Bacteria have evolved complex resistance strategies, such as enzyme production to neutralize drugs, modifying drug targets, and using efflux pumps to remove antibiotics, significantly reducing drug efficacy. …”
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Potency of the Consortium of Pseudomonad fluorescent pf-142 and Bacillus mycoides Isolates Against Bacterial Wilt Disease In-Vitro by Yosua Nathanael Itona Sagala, Endang Triwahyu Prasetyawati, Yenny Wuryandari

“…The variables observed were the symptoms of attack and pathogenicity of R. solanacearum, compatibility and inhibitory rate of the consortium of Pseudomonad fluorescens pf-142 and B. mycoides against R. solanacearum. …”
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Identification of a comprehensive set of transcriptional regulators involved in the long-term survivability of Escherichia coli in soil by Soma Nakamoto, Ikki Kobayashi, Koichi Watanabe, Takeru Kikuta, Sousuke Imamura, Tomohiro Shimada

“…These transcription factors are often global regulators and conserved among other pathogenic bacterial species. Taken together, we successfully identified a comprehensive set of transcription factors involved in the long-term survival of E. coli in soil. …”
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Substantiation of application and estimation of efficacy of probiotics at inflammatory bowel diseases by Ye. A. Poluektova, Yu. O. Sidorina, S. Yu. Kuchumova, A. V. Korolev, O. S. Shifrin

“…At patients with IBD the intestinal microbiome have quantitative and qualitative differences from microbiome of healthy patients aside of increase in contents of opportunistic and pathogenic microorganisms. Microbiome changes result in initiation of cascade of pathological immune reactions of the host in related to presence of genetical defects, that, in turn, promotes development of clinical symptoms and morphological changes in intestinal wall. …”
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Differential Diagnosis of MutYH-Associated Polyposis from Sporadic Colon Polyps by A. S. Tsukanov, V. P. Shubin, A. M. Kuzminov, M. Kh. Toboeva, T. A. Savelyeva, V. N. Kashnikov, Yu. A. Shelygin

“…Mutations in the MutYH gene were not detected in patients with 4–19 polyps (p <0.05). The pathogenic significance of the disease development was established not only for biallelic, but also for monoallelic mutations.Conclusion. …”
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An Exhaled Breath Sampler Based on Condensational Growth and Cyclone Centrifugation (BSCC) by Lebing Wang, Jianguo Deng, Dongbin Wang, Menghao Chen, Xue Li, Yun Lu, Jingkun Jiang

“…This enables rapid sample collection and eliminates certain pre-treatment steps for pathogenic microorganism analysis. Laboratory-generated aerosols were mixed with saturated water vapor to simulate exhaled breath, and the collection efficiency and the virus infectivity conservation efficiency of the BSCC were evaluated. …”
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A new crustin-like gene from the redclaw crayfish Cherax quadricarinatus and its response to decapod iridescent virus 1 (DIV1) challenge by Xiaoying Hang, Jianbo Zheng, Fei Li

“…Crustin, a widely-studied antimicrobial peptides (AMPs), has been proven to be involved in mediating innate immune responses against intruding pathogens. In this study, a novel crustin-like gene, Cqcarc1, was characterized from the redclaw crayfish Cherax quadricarinatus. …”
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Diseases impact the performance of maize hybrids in southern Minas Gerais by Guilherme Vieira Pimentel, Luiz Daniel Rodrigues da Silva, Natalia Costa, Amanda Santana, Elisabete da Cruz Silva Watanabe, Silvino Guimarães Moreira

“…The evaluated traits were: severity (%) of foliar and ear diseases, incidence (%) of pathogens in grains, plant and ear height, yield, weight of 100 grains and final stand. …”
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Comparison of chemical constituents in Lysimachia species and their antimicrobial activity for extending the shelf life of foods by Li-Li Chen, Shuang Long Yang, Ji-Cun Bao, Wei-You Xie, Zhao-Chan Wang, Nian Shi, Zhao-Jie Wang

“…The KBZZC-05, 21, and 23 inhibited both spoilage organisms and foodborne pathogens (MICs = 2–256 μg/mL) better than potassium sorbate (MIC >256 μg/mL). …”
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Protein arginine methyltransferase 7 linked to schizophrenia through regulation of neural progenitor cell proliferation and differentiation by Ting Shen, Jing Yu, Bin Xie, Cuiping Huang, Jingjie Cui, Kefu Liu, Chunyu Liu, Chao Chen

“…Summary: Genome-wide association studies (GWASs) have identified numerous genomic loci linked to schizophrenia (SCZ), while their pathogenic mechanisms largely remain unclear. This study demonstrated protein arginine methyltransferase 7 (PRMT7) as a key target of SCZ risk SNPs with allele-specific enhancer activity at 16q22.1. …”
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Diagnostics and treatment of biliary dyskinesia: clinical guidelines of the Russian gastroenterological Association by V. T. Ivashkin, I. V. Mayev, Yu. O. Shulpekova, Ye. K. Baranskaya, A. V. Okhlobystin, A. S. Trukhmanov, T. L. Lapina, A. A. Sheptulin

“…Contractility disorders along with increased lithogenicity followed by cyclooxygenase-2 overactivation in biliary tract tissue play significant pathogenic role; putative change in bile acid composition may be involved as well. …”
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Principles of portal hypertension treatment at patients with liver cirrhosis by Ye. A. Fedosina, M. V. Mayevskaya, V. T. Ivashkin

“…As the major part of these states peripheral vasodilation, prescription of vasoconstrictors (first of all — terlipressin) is pathogenically justified and results in arrest of acute bleedings from esophageal VV, and in functional recovery of kidneys at renal failure.…”
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Hypercalcemia and co-occurring TBX1 mutation in Glycogen Storage Disease Type Ib: case report by Zakaria Kasmi, Imane Ain El Hayat, Zahra Aadam, Abderrahmane Errami, Ibtihal Benhsaien, Jalila EL Bakkouri, Dalal Ben Sabbahia, Meryem Atrassi, Ahmed Aziz Bousfiha, Fatima Ailal

“…Genetic testing confirmed a homozygous pathogenic variant in SLC37A4 and a heterozygous variant of uncertain significance in TBX1. …”
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Antibiotic resistance gene occurrence in poultry farms in northeast Brazil by Henrique Francisco de Almeida, Paulo Ricardo Conceição Marques Trindade, César Roberto Viana Teixeira, Claudson Oliveira Brito, Silvio Santana Dolabella, Sona Jain, Maíra Pompeu Martins, Ana Andréa Barbosa

“… The misuse of antibiotics in food-producing animal farming practices exerts selective pressure on bacterial strains, intensifying the spread of pathogenic and commensal bacteria carrying antibiotic resistance genes (ARGs). …”
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A novel isothermal whole genome sequencing approach for Monkeypox Virus by Matthias Licheri, Manon Flore Licheri, Lukas Probst, Cora Sägesser, Pascal Bittel, Franziska Suter-Riniker, Ronald Dijkman

“…Whole genome sequencing (WGS) has been successfully used to keep track of viral evolution during outbreaks or for surveillance of multiple pathogens of public health significance. Current WGS protocols for MPXV are either based on metagenomic sequencing or tiled-PCR amplification. …”
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Parathyroid carcinoma and pheochromocytoma in a patient with neurofibromatosis type 1: a rare association by Jardelina Brena Rocha Leite, Nicole Ramalho De Freitas, Rafaella Nelice de Holanda Cardoso, Erik Trovão Diniz, Gabriel Rodrigues de Assis Ferreira, Fernão Henrique Costa e Alvim, Camila Ribeiro Coutinho Madruga, Ana Carolina Thé Garrido, Luciano Albuquerque, Patricia Sampaio Gadelha, Ruy Lyra, Lucio Vilar

“…Genetic analysis corroborated NF1 with a pathogenic variant in the NF1 gene. The patient’s clinical manifestations, coupled with the presence of café-au-lait spots and axillary freckles, supported the diagnosis of NF1. …”
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Case report: Hypoparathyroidism-sensorineural hearing loss-renal dysplasia without febrile seizures: a novel mutation in the GATA3 gene by Haibin Chen, Haibin Chen, Yudi Zhang, Xueyao Yang, Xueyao Yang, Yongzhen Li

“…The missense mutation was determined to be both pathogenic and novel.ConclusionEarly genetic testing should be prioritized, and regular monitoring of kidney development and hearing status is essential. …”
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