Budget Impact of Rivaroxaban for the Prevention of Thromboembolic Events after Hip or Knee Replacement in Spain by Xavier Granero Xiberta, Antonio Murcia, José Ricardo Troncoso Durán, Claudio Gómez Zubeldia, Aleix Llorac Moix, Ruth Graefenhain De Codes, Maria Giovana Ferrario, Luis Lizán

“…**Background:** Anti-thrombotic prophylaxis is routinely used in patients undergoing elective total hip or knee replacement (THR or TKR) to reduce the risk of venous thromboembolism (VTE). In Spain, pharmacological prophylaxis is performed with low-molecular-weight heparin, enoxaparin being the most commonly used. …”
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The effects of Thymus capitatus essential oil topical application on milk quality: a systems biology approach by Ralph Nehme, Chiara Gini, Elise Vanbergue, Sergine Even, Filippo Biscarini, Sonia Andrés, Lucie Rault, Faustine Noel, Valerie Hardit, Said Bouhallab, David M. Pereira, Riadh Ksouri, Philippe Roussel, Secundino López, Paola Cremonesi, Bianca Castiglioni, Donatella Caruso, Fiorenza Faré, Manuela Fontana, Fabrizio Ceciliani, Latifa Abdennebi-Najar

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Safety evaluation of ethanol extract from Artocarpus altilis leaves as a herbal medicine candidate: Studies in acute and subchronic toxicity by Fitrya Fitrya, Elfita Elfita, Ferlinahayati, Salma Fayzah Septami, Umi Tsalsa Sabrina, Fatma Sri Wahyuni, Annisa Amriani, Rennie Puspa Novita

“…Background: Artocarpus altilis is a traditional medicine proven to be efficacious in several pharmacological tests using animal models. However, there have been no reports regarding its safety so far. …”
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From guideline to practice: three years of ICH S11 insights and recommendations by Diana Tavares, Hsiao-Tzu Chien, Hsiao-Tzu Chien, Maria Elzbieta Sheean, Peter Theunissen, Peter Theunissen, Peter van Meer, Peter van Meer, Peter van Meer, Karen Van Malderen

“…A thorough consideration of developmental aspects of the product’s pharmacological target, the clinical relevance of notable toxicity findings, and the clinical context of the medicine’s use fosters effective dialogue and improves regulatory alignment. …”
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Personalized prediction of anticancer potential of non-oncology drugs through learning from genome derived molecular pathways by Xiaobao Dong, Huanhuan Liu, Ting Tong, Liuxing Wu, Jianhua Wang, Tianyi You, Yongjian Wei, Xianfu Yi, Hongxi Yang, Jie Hu, Haitao Wang, Xiaoyan Wang, Mulin Jun Li

“…Utilizing protein–protein interaction networks, CHANCE harmonizes multilevel mutation annotations and integrates pharmacological information across different drugs into a single model. …”
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Flavonoid Compounds from Ethanol Extract of Sungkai Leaves (Peronema canescens. Jack) and Antibacterial Activity Test Against Staphylococcus epidermidis and Escherchia coli by Nindita Clourisa Amaris Susanto, Jammes Ardhica, Nelson, Madyawati Latief

“…Traditional medicinal plants have been widely recognized for their therapeutic potential, and Peronema canescens Jack is well-known to contain bioactive compounds. Among its pharmacological properties, its antibacterial potential has drawn scientific interest. …”
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The Lollipop with Lemon Aroma May Be Promising in Nausea and Vomiting in Pregnancy by Ismail Biyik, Fatih Keskin

“…Lemon-flavored lollipops are cheap and easily accessible and therefore promising as a non-pharmacological complementary treatment for nausea and vomiting of pregnancy. …”
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Amentoflavone from Selaginella bryopteris leaf extracts modulate MAPK signaling - Molecular modeling study for therapeutic target analysis by Praveen Mallari, Mashooq Ahmad Bhat

“…Subsequent research aims to characterize individual bioactive phytochemicals and their mode of action for possible pharmacological application.…”
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Brivaracetam to Treat Partial Onset Seizures in Adults by Dustin Latimer, David Le, Evan Falgoust, Patrick Ingraffia, Alaa Abd-Elsayed, Elyse M. Cornett, Rupin Singh, JooHee Choi, Giustino Varrassi, Adam M. Kaye, Alan D. Kaye, Latha Ganti

“… # Conclusion The treatment of epilepsy with pharmacologic agents is a difficult task due to balancing the efficacy of the drug with the side effect profile that will allow for the best quality of life for the patient. …”
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Immunological Approaches and Different Strategies for Vaccine Development Against SARS-COV-2 by Muhammed Babakir-Mina

“…Moreover, there are different strategies that used by researchers and pharmacological companies to develop vaccines including attenuated or killed viruses, RNA of a spike protein, and vector expressing a particular protein of the virus. …”
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Management of a Female Patient with Irritable Bowel Syndrome and Somatoform Disorder by E. A. Trush, E. A. Poluektova, A. G. Beniashvili, O. S. Shifrin

“…Kolofort can be the drug of choice both in patients with IBS and the pharmacological part of therapy in patients with somatization disorder.…”
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Rheumatoid-like hand deformities and aortic valve disease in a 13-year-old girl with homozygous familial hypercholesterolemia: a case report by Anjuman Ara Rahman, Abhijit Datta, Kamal Uddin Ahmed, Anindita Das Barshan, Mohammad Jahid Hasan

“…Early detection allows timely intervention, such as lifestyle modifications and pharmacological treatments, which can significantly reduce these risks. …”
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The Effects of Six Weeks of Patella Taping on Function, Proprioception, and Balance in Women with Knee Osteoarthritis by Maryam Alikhani, Hamid Tabatabai

“…Patella taping may be an effective non-pharmacological tool for enhancing these outcomes and is recommended for use by sports trainers and physiotherapists.…”
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Post-chemoradiotherapy adjuvant chemotherapy of rectal cancer by E. V. Ledin, A. V. Kochatkov

“…To present the analysis of available data on approach to pharmacological antineoplastic therapy at rectal cancer (RC) after chemoradiotherapy followed by surgical treatment, as well as within the «watch & wait» concept. …”
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The Effect of Six Weeks of Patella Taping on Pain in Women with Knee Osteoarthritis by Maryam Alikhani, Hamid Tabatabai

“…Therefore, sports trainers and physiotherapists are encouraged to consider patella taping as a non-pharmacological intervention to alleviate pain in women with knee osteoarthritis.…”
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Effects of photobiomodulation therapy in patients with chronic non-specific low back pain: protocol for a randomised placebo-controlled trial by Lucíola da Cunha Menezes Costa, Shaiane Silva Tomazoni, Leonardo Oliveira Pena Costa, Layana de Souza Guimarães, Amanda Costa Araujo, Dafne Port Nascimento, Flávia Cordeiro de Medeiros, Marina Athayde Avanzi

“…Photobiomodulation therapy (PBMT) is a frequently used non-pharmacological therapy for the treatment of musculoskeletal disorders. …”
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Design, synthesis and biological evaluation of buthutin derivatives as cardioprotective agents by Yuan Liu, Fa-Qi Wang, Xin-Hao Hua, Shu-Han Yang, Li-Ning Wang, Yun-Sheng Xu, Chen-Yue Shao, Xiang-Bo Gou, Yu-Ming Liu

“…The structure–activity relationship (SAR) studies suggested that the presences of amide group, four-carbon linker, and para hydroxyl benzene ring were advantageous pharmacophores for above two pharmacological actions. This research would open new avenues for developing amide-guanidine-based cardioprotective agents. …”
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Effect of hypnotherapy on paediatric cancer pain management in Indonesia: A quasi-experimental study by Sri Hartini M.A, Nafisatun Nisa, Satriya Pranata, Mudy Oktiningrum, Sri Puguh Kristiawati

“…Hypnotherapy, a non-pharmacological intervention, has shown promise in pain management. …”
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Glucagon-like peptide 1 receptor agonists in obesity treatment - a literature review by Aleksander Jentkiewicz, Esmail Haj Obeid, Jakub Ulrych, Jan Krupa, Maciej Malinowski, Michał Krasowski, Alicja Kalinowska, Wiktoria Pietras, Adrian Kozieł, Zofia Kurek

“…Tirzepatide and semaglutide are two pharmacological agents which show best results in terms of weight loss.   …”
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Patient Management in Non-Alcoholic Fatty Liver Disease and Type 2 Diabetes Mellitus by A. E. Bagriy, A. D. Zubov, M. V. Khomenko, E. S. Mikhailichenko, E. A. Pylaeva, N. A. Khaustova, E. V. Bryukhovetskaya

“…A current overview of non-pharmacological and drug-based approaches to non-alcoholic fatty liver disease (NAFLD) combined with type 2 diabetes mellitus (T2D).Key points. …”
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