Efficacy analysis of folic acid in chronic atrophic gastritis with Helicobacter pylori infection: a systematic review and meta-analysis by Hui Li, Jincheng Li, Mingyu Lai

“…Results 16 randomized controlled trials with 1364 patients were included. …”
Get full text

Effect of exercise training on cardiac autonomic function in type 2 diabetes mellitus: a systematic review and meta-analysis by Sohini Raje, G Arun Maiya, Padmakumar R, Mukund A. Prabhu, Krishnananda Nayak, Shivashankara KN, BA Shastry, Megha Nataraj

“…The Cohrane ROB-2 tool was used for randomized controlled trials (RCTs) and the ROBINS-I tool for non-RCT for risk of bias assessment were used. …”
Get full text

Effect of a Balance Adjustment System on Postural Control in Patients with Chronic Ankle Instability by Kazushi Yoshida, Rieko Kuramochi, Junji Shinohara

“… # Level of Evidence Level Ⅰ, randomized control trial…”
Get full text

Effect of Low-Load Blood Flow Restriction Training After Anterior Cruciate Ligament Reconstruction: A Systematic Review by Baris B. Koc, Alexander Truyens, Marion J.L.F. Heymans, Edwin J.P. Jansen, Martijn G.M. Schotanus

“… # Results A total of six randomized controlled trials were included. Random sequence generation and allocation concealment was defined as high risk in two of the six studies. …”
Get full text

Comparison of the safety of remimazolam and propofol during general anesthesia in elderly patients: systematic review and meta-analysis by Xianchun Liu, Longyi Zhang, Li Zhao, Xuelei Zhou, Wei Mao, Linlin Chen, Hongyu Zhu, Ying Xie, Linji Li

“…Data extraction and quality assessment were performed independently by two researchers.ResultsEight randomized controlled trials involving 571 participants were included. …”
Get full text

Scoping Review of PTSD Treatments for Natural Disaster Survivors by Arjun Nanduri, Marlon Vasquez, Savithri Chandana Veluri, Noshene Ranjbar

“…It includes fourteen randomized control trials (RCTs). The included interventions were, pharmaceuticals, nutraceuticals, herbal supplements, CBT, yoga, narrative exposure therapy, acupuncture stimulation, web-based interventions, and a multimodal art and meditation program. …”
Get full text

Evidence Graph Analysis of Postoperative Pain Sensitization Induced by Perioperative Sleep Deprivation by XUE Jianjun, WANG Caihong, GUO Lingling, LI Xiuxia, ZHANG Jie, XU Ziqing, HOU Huaijing, YANG Kehu

“…The number of publications increased rapidly after 2018 and peaked in 2022, and clinical studies in this field mainly focused on cohort studies, with fewer randomized controlled trials and systematic reviews/Meta-analysis studies. …”
Get full text

A comprehensive review of urinary tract fistulas: the evolution of etiologies, surgical techniques, and contemporary outcomes by Noah Nigro, Gary Shahinyan, Shujian Lin, Rohan G. Bhalla, Brian J. Flynn

“…The study concludes with advocacy for more widespread access to the RAL platform as well as more research, including randomized controlled trials, to further refine the body of evidence and promote patient outcomes.…”
Get full text

An Overview of the Impact of Statin Therapy on Cardiac Incident Risk by Urszula Świrk, Aleksandra Paprocka, Karolina Kalinowska, Paulina Fijałek, Jan Karczmarz, Marika Gutowska, Agnieszka Kosińska, Wiktoria Belcarz, Joanna Orzechowska, Michał Orzechowski

“…Evidence from large-scale randomized controlled trials and meta-analyses consistently demonstrates that statins significantly reduce the incidence of major cardiovascular events by lowering low-density lipoprotein (LDL) cholesterol levels and exerting pleiotropic effects like improving endothelial function and stabilizing atherosclerotic plaques. …”
Get full text

Eclecticism in child welfare by Terje Halvorsen

“…Several researchers then advocated a clean-up campaign where one through randomized controlled trials should decide which theories are true and which methods work. …”
Get full text

Orthoplastic surgery research: Three decades of growth and future directions by Alexander F. Dagi, Michael B. Amrami, Nikhil A. Gangoli, Dylan K. Kim, Jarrod T. Bogue

“…While meta-analyses support the clinical benefits of orthoplastic management for complex fractures, showing reduced surgical interventions and infection rates, the evidence base relies predominantly on retrospective studies, with no randomized controlled trials identified. Key opportunities to strengthen the field include conducting prospective studies, expanding research beyond lower extremity trauma to areas such as upper extremity reconstruction, oncologic applications, and paediatric care, addressing healthcare access disparities, evaluating cost-effectiveness across different healthcare systems, and developing standardized guidelines beyond the UK.…”
Get full text

Effects Of Hormonal Supplements In Women with Poor Ovarian Response Undergoing Assisted Reproductive Technology by Silan Melis Bozan, Gurkan Bozdag

“…However, there is a need to support the available data with further randomized controlled trials seeking for live birth rate as the primary outcome. …”
Get full text

Application of oral nutritional supplements to control body weight loss in postoperative patients suffering from solid tumors: a systematic review and meta-analysis by Ying Liu, Zhen Wu, Tingting Shao, Wanzhen Zheng, Jing Huang

“…Data from eligible studies were extracted, and pooled mean differences (MD) along with their 95% confidence intervals (CIs) for BWL were computed.ResultsA total of 12 randomized controlled trials (RCTs) with 2,268 participants were finally included. …”
Get full text

Lipedema: Clinical Features, Diagnosis, and Management by Hatan Hisham Mortada, Abdulmalek W. Alhithlool, Nouf Z. AlBattal, Rashika K. Shetty, Ghaleb A. AL-Mekhlafi, Joon Pio Hong, Feras Alshomer

“…Further high-quality randomized controlled trials are urgently needed to continue advancing our understanding of this often neglected disease and exploring optimal medical and surgical treatment regimens tailored specifically for lipedema patients. …”
Get full text

Health Implications of Anabolic-Androgenic Steroids: Usage, Risks, and Treatment Approaches - The Literature Review by Krzysztof Jodłowski, Ewa Dubniewicz, Paula Majewska, Alicja Staszek, Wiktoria Łoskot, Jan Szwech, Mateusz Matczak, Karol Jasiński, Aleksandra Broda, Kacper Hoksa

“…Despite the growing concern over AAS misuse, current research is limited by methodological constraints, including a lack of randomized controlled trials and long-term studies. The review explores the health implications of AAS use, highlighting the importance of an interdisciplinary approach to managing AAS-related health issues, emphasizing harm reduction, pharmacological interventions, and fertility preservation techniques. …”
Get full text

Viloxazine, a Non-stimulant Norepinephrine Reuptake Inhibitor, for the Treatment of Attention Deficit Hyperactivity Disorder: A 3 Year Update by Hannah W Haddad, Paul B. Hankey, Jimin Ko, Zahaan Eswani, Pravjit Bhatti, Amber N. Edinoff, Adam M. Kaye, Alan D. Kaye

“…Phase 2 and 3 randomized control trials have demonstrated significant efficacy of viloxazine in improving ADHD symptoms versus placebo. …”
Get full text

Role of stem cells on motor function recovery in stroke patients: systematic review by Babita Raghuwanshi, Suresh K. Thanneeru, Roshan Chanchalani, Sumit Raj, Pradeep Chouksey, Md Yunus, Amit Agrawal

“…Future well-designed, robust randomized controlled trials are necessary to evaluate the efficacy, safety, and ethical implications of stem cell therapy for motor recovery in stroke patients.…”
Get full text

Meralgia Paresthetica Review: Update on Presentation, Pathophysiology, and Treatment by Yanet de la Caridad Gomez, Edgar Remotti, Deandra Uju Momah, Emily Zhang, Daniel D. Swanson, Rosa Kim, Ivan Urits, Alan D. Kaye, Christopher L Robinson

“…Further research including randomized controlled trials are needed to better understand the most optimal treatment options for MP including studies with a larger number of participants.…”
Get full text

Treatment of convulsive status epilepticus in Brazil: a review by Luis Otavio Caboclo

“…In the absence of randomized controlled trials, treatment should be guided by the physician's experience, clinical judgment, and established therapeutic options from previous reports.…”
Get full text

Validity of a Sham Dry Needling Technique on a Healthy Population by Daniel M Cushman, Anna Holman, Lee Skinner, Keith Cummings, Peter Haight, Masaru Teramoto

“…This technique may be useful for randomized controlled trials in the future. # Levels of Evidence 2…”
Get full text