The WAVE complex in developmental and adulthood brain disorders by Hyung-Goo Kim, Clara Berdasco, Angus C. Nairn, Yong Kim

“…The activity of the WAVE complex is tightly regulated by extracellular cues and intracellular signaling to execute its roles in specific intracellular events in brain cells. …”
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Annex G of the 2001 Agreement on Succession Issues: Self-executing or Not? by Vesna Crnić-Grotić, Sandra Fabijanić Gagro, Petra Perišić

“…Specifically, Annex G of the Agreement regulated the issue of the protection of private property and acquired rights of citizens and legal persons of ex-Yugoslavia, requiring their protection by the successor States. …”
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Targeting ceramide transfer protein sensitizes AML to FLT3 inhibitors via a GRP78-ATF6-CHOP axis by Xiaofan Sun, Yue Li, Juan Du, Fangshu Liu, Caiping Wu, Weihao Xiao, Guopan Yu, Xiaowei Chen, Robert Peter Gale, Hui Zeng

“…Abstract Sphingolipid, ceramide for example, plays an essential role in regulating cancer cell death. Defects in the generation and metabolism of ceramide in cancer cells contribute to tumor cell survival and resistance to chemotherapy. …”
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Cardiac repair using regenerating neonatal heart tissue-derived extracellular vesicles by Hanjing Li, Yining Liu, Yuqing Lin, Sijia Li, Chenlu Liu, Ao Cai, Wei Li, Wanyu Zhang, Xinlu Gao, Zhongyu Ren, Haoyu Ji, Yang Yu, Xiuxiu Wang, Wenya Ma, Ning Wang, Dan Zhao, Tianlong Li, Yu Liu, Benzhi Cai

“…Proteomic analysis reveals the expression of Wdr75 protein, a regulator of p53, is higher in AR-Neo-EVs than in Neo-EVs. …”
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Examining inclusivity: the use of AI and diverse populations in health and social care: a systematic review by John Gabriel O. Marko, Ciprian Daniel Neagu, P. B. Anand

“…A holistic approach must be used to address disparities, enforce effective regulations, safeguard privacy, promote inclusion and equity, and emphasize rigorous validation.…”
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A low-carbon scheduling method based on improved ant colony algorithm for underground electric transportation vehicles by Yizhe Zhang, Yinan Guo, Yao Huang, Shirong Ge

“…The model incorporates constraints related to load capacity, cruising range, and safety regulations. A specific energy consumption model for ETVs is formulated, considering factors such as road conditions, load, and driving state. …”
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Nrf2 phosphorylation contributes to acquisition of pericyte reprogramming via the PKCδ pathway by Rika Sakuma, Yusuke Minato, Seishi Maeda, Hideshi Yagi

“…PKCδ inhibitor treatment suppressed pNrf2 activation and restored the down-regulated expression of stem cell markers in iPCs in vitro. …”
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Morphological, physiological, element absorption, and transcriptomic analysis reveals the mechanism of 2-(3,4-Dichlorophenoxy) trimethylamine alleviating copper stress in cucumber... by Yang Li, Xiaoning Wang, Mengwei Huang, Yijing Xing, Xueting Wang, Hu Wang, Meng Li, Qingjie Du, Huaijuan Xiao, Jiqing Wang, Juanqi Li

“…This study has demonstrated that DCPTA reduces the impact of copper stress on plants by enhancing leaf pigment and photosynthesis, regulating root growth, and balancing the antioxidant system. …”
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Noise pollution in developing countries: Loopholes and recommendations for Vietnam law by Quang Chinh Nguyen, An Thanh Thi Chu, Bao Gia Truong, Duyen Hong Thuc Nguyen

“…Although noise pollution and control are receiving more attention from the authorities, no significant improvement is attained. Regulations on noise pollution in Vietnam are scattered, only providing general principles without clear guidance on sources, national plans, noise maps, and criminal liability. …”
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Hustle Culture: Loopholes in Violations of Employment Law by Ellen Lutya Putri Nugrahani, Jody Imam Rafsanjani, Zaihan Harmaen Anggayudha, Hilmi Ardani Nasution

“…However, it is often exploited to justify practices that violate labor laws, such as forcing employees to work beyond regulated hours without fair overtime pay or compensation. …”
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Virgin and photo-degraded microplastics induce the activation of human vascular smooth muscle cells by Elisa Persiani, Antonella Cecchettini, Sofia Amato, Elisa Ceccherini, Ilaria Gisone, Agnese Sgalippa, Chiara Ippolito, Valter Castelvetro, Tommaso Lomonaco, Federico Vozzi

“…Key markers like RUNX-2 and galectin-3, which regulate cardiovascular pathology, were activated, alongside the inflammasome complex. …”
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The endocytic adaptor AP-2 maintains Purkinje cell function by balancing cerebellar parallel and climbing fiber synapses by Marianna Tolve, Janine Tutas, Ebru Özer-Yildiz, Ines Klein, Anne Petzold, Veronika J. Fritz, Melina Overhoff, Quinn Silverman, Ellie Koletsou, Filip Liebsch, Guenter Schwarz, Tatiana Korotkova, Silvana Valtcheva, Graziana Gatto, Natalia L. Kononenko

“…These findings highlight the role of AP-2 in regulating GRID2IP levels in Purkinje cells to maintain PF-CF synaptic balance and prevent motor dysfunction.…”
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Spatial proteomics identifies a CRTC-dependent viral signaling pathway that stimulates production of interleukin-11 by Benjamin J. Ravenhill, Marisa Oliveira, George Wood, Ying Di, Joanne Kite, Xinyue Wang, Colin T.R. Davies, Yongxu Lu, Robin Antrobus, Gill Elliott, Nerea Irigoyen, David J. Hughes, Paul A. Lyons, Betty Chung, Georg H.H. Borner, Michael P. Weekes

“…To comprehensively identify signaling factors, we analyzed protein relocalization on a global scale during viral infection. cAMP-responsive element-binding protein (CREB)-regulated transcription coactivators 2 and 3 (CRTC2/3) exhibited early cytoplasmic-to-nuclear translocation upon infection with multiple viruses in diverse cell types. …”
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Single cell suppression profiling of human regulatory T cells by Jonas Nørskov Søndergaard, Janyerkye Tulyeu, David Priest, Shimon Sakaguchi, James B. Wing

“…Abstract Regulatory T cells (Treg) play an important role in regulating immune homeostasis in health and disease. …”
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Homeostasis and metabolism of iron and other metal ions in neurodegenerative diseases by Leilei Chen, Qingqing Shen, Yingjuan Liu, Yunqi Zhang, Liping Sun, Xizhen Ma, Ning Song, Junxia Xie

“…Then, the upstream regulators, downstream effector, and crosstalk of mental ions under both physiologic and pathologic conditions will be summarized. …”
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Analysing Informal Governance Arrangements in Small-Scale Fisheries: A Case Study of Norton, Zimbabwe by Tawanda Jimu, Samantha Williams, Manfred Spocter

“…This formal centralised system is poorly regulated, and challenges exist when implementing management strategies. …”
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Functional-proteomics-based investigation of the cellular response to farnesyltransferase inhibition in lung cancer by Yanbo Pan, Olena Berkovska, Soumitra Marathe, Georgios Mermelekas, Greta Gudoityte, Amare D. Wolide, Taner Arslan, Brinton Seashore-Ludlow, Janne Lehtiö, Lukas M. Orre

“…Additionally, we identified a synergistic drug combination involving tipifarnib and a ferroptosis inducer and discovered PTP4A1 as a regulator of interferon signaling. Our data, covering 15,080 proteins, offer valuable insights for future studies of farnesylation and FTIs.…”
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Development and Assessment of an Online, Asynchronous State-Specific Pharmacy Law Continuing Education Program for Multistate Pharmacy Jurisprudence Examination Preparation by Apryl Peddi, Lauren Caldas, Evan Sisson, Sofia Yousufzai, Laura Frankart

“…Description of the Innovation: The Virginia Commonwealth University School of Pharmacy created an online, asynchronous continuing education (CE) course that provides content specific to Virginia pharmacy laws and regulations. The course is divided into six modules, aligned with MJPE competency statements. …”
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INVESTIGATING THE COST EFFECTIVENESS OF BIODIESEL DISTRIBUTION IN INDONESIA by Herbert Wibert Victor Hasudungan, Elis Heviati, Sulthon Sjahril Sabaruddin, Sigit Hargiyanto

“…Given that fuel prices fluctuate periodically, we also argue that the cost differences between the regulated and formulated reference may arise due to i) the data inaccuracy of the diesel fuel consumption and ii) specific terms outlined in the agreement between the corresponding transporters and suppliers. …”
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Assessing the Concentration of Agrochemicals in Water Sources in Mbarara District: A Case Study: River Rwizi Mbarara. by Mujurizi, Barnabas

“…Key objectives include characterizing agrochemical levels, analyzing physiochemical parameters of water quality, and evaluating compliance with environmental regulations. Data collection involved sampling at strategic points along the River Rwizi, with laboratory analysis of fertilizer concentrations. …”
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