A socio-ecological model of the management of leprosy reactions in Indonesia and India using the experiences of affected individuals, family members and healthcare providers by Annisa Ika Putri, Ruth M. H. Peters, Kevin De Sabbata, Brittney S. Mengistu, Regitta I. Agusni, Medhi Denisa Alinda, Joydeepa Darlong, M. Yulianto Listiawan, Cita R. S. Prakoeswa, Stephen L. Walker, Marjolein B. M. Zweekhorst

“…Results This study highlights the significant impact of public health insurance regulations and uptake at the macrosystem level on the provision of healthcare services, clinical decision-making, care expenditure, and the psychological well-being of individuals with LR in Indonesia and India. …”
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Sistem Kontrol Swarm untuk Flocking Wahana NR-Awak Quadrotor dengan Optimasi Algoritma Genetik by Endra Joelianto, Winarendra Satya Rajasa, Agus Samsi

“…Pengontrol pertama menggunakan pengontrol proporsional derivatif (PD), sedangkan pengontrol kedua menggunakan regulator linier kuadratik (RLK). Pengontrol yang dirancang memiliki parameter yang banyak, sehingga pemilihan parameter yang optimal sangat sulit. …”
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Addressing the toxic chemicals problem in plastics recycling by Bethanie Carney Almroth, Eric Carmona, Nnaemeka Chukwuone, Tridibesh Dey, Daniel Slunge, Thomas Backhaus, Therese Karlsson

“…To address this problem, we suggest the following policy strategies: 1) improved reporting, transparency and traceability of chemicals in plastics throughout their full life cycle; 2) chemical simplification and group-based approaches to regulating hazardous chemicals; 3) chemical monitoring, testing and quality control; 4) economic incentives that follow the waste hierarchy; and 5) support for a just transition to protect people, including waste pickers, impacted throughout the plastics life cycle.…”
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Bienestar psicológico y ansiedad competitiva: el papel de las estrategias de afrontamiento / Competitive Anxiety and Psychological Well-being: the Role of Coping Strategies by Enrique Cantón-Chirivella, Irene Checa-Esquiva, María Yolanda Vellisca-González

“…The results predict, through regression analysis, the possibility of experiencing anxiety and psychological well-being in the competitive context, regulated by the mediator of task-directed coping strategies. …”
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Micromechanical behavior of the apple fruit cuticle investigated by Brillouin light scattering microscopy by Timm Landes, Bishnu P. Khanal, Hans Lukas Bethge, Tina Lehrich, Maximilian Seydi Kilic, Franz Renz, Miroslav Zabic, Moritz Knoche, Dag Heinemann

“…Abstract The cuticle is a polymeric membrane covering all plant aerial organs of primary origin. It regulates water loss and defends against environmental stressors and pathogens. …”
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Development and Efficiency Analysis of Dual Active Bridge Converter Employing SiC Devices Using TMS 320F280039 by T. Deepti, K. Deepa, Albert Alexander Stonier, Geno Peter, A. Anoop, Vivekananda Ganji

“…Furthermore, this study presents a closed-loop voltage controller that effectively regulates the output voltage in the presence of significant variations in both the input line and load conditions. …”
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Digital Markets and Data Exploitation: Addressing Abuse of Dominance Under Indonesian Competition Law by Moch. Marsa Taufiqurrohman, Helza Nova Lita, Gress Gustia Adrian Pah

“…The article concludes by suggesting that lawmakers should establish a framework and adequate regulations to address the exploitation of personal data by business actors in the digital market. …”
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Accelerated photonic design of coolhouse film for photosynthesis via machine learning by Jinlei Li, Yi Jiang, Bo Li, Yihao Xu, Huanzhi Song, Ning Xu, Peng Wang, Dayang Zhao, Zhe Liu, Sheng Shu, Juyou Wu, Miao Zhong, Yongguang Zhang, Kefeng Zhang, Bin Zhu, Qiang Li, Wei Li, Yongmin Liu, Shanhui Fan, Jia Zhu

“…Here, using a synergistic genetic algorithm and machine learning, we propose and demonstrate a coolhouse film that regulates temperature and water for photosynthesis without requiring additional energy or water. …”
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An Integrated Database for Exploring Alternative Promoters in Animals by Feiyang Xue, Yuqin Yan, Weiwei Jin, Haotian Zhu, Yanbo Yang, Zhanhui Yu, Xuewen Xu, Jing Gong, Xiaohui Niu

“…Abstract Alternative promoter (AP) events, as a major pre-transcriptional mechanism, can initiate different transcription start sites to generate distinct mRNA isoforms and regulate their expression. At present, hundreds of thousands of APs have been identified across human tissues, and a considerable number of APs have been demonstrated to be associated with complex traits and diseases. …”
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Metabolic deficiencies underlie reduced plasmacytoid dendritic cell IFN-I production following viral infection by Trever T. Greene, Yeara Jo, Carolina Chiale, Monica Macal, Ziyan Fang, Fawziyah S. Khatri, Alicia L. Codrington, Katelynn R. Kazane, Elizabeth Akbulut, Shobha Swaminathan, Yu Fujita, Patricia Fitzgerald-Bocarsly, Thekla Cordes, Christian Metallo, David A. Scott, Elina I. Zúñiga

“…Mechanistically, we identify lactate dehydrogenase B (LDHB) as a positive regulator of pDC IFN-I production in mice and humans; meanwhile, LDHB deficiency is associated with suppressed IFN-I production, pDC metabolic capacity, and viral control following infection. …”
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Developing Halal Tourism Based on Local Wisdom in Religious Area of Sis Aljufri by Suhri Hanafi, Nadia Nadia, Muhammad Syarif Nurdin, Sitti Nurkhaerah, Zaiton Osman

“…However, realizing this potential faces challenges related to the provision of halal facilities and the enforcement of government regulations. This research aims to analyze the development of halal tourism in the Sis Aljufri Religious Area based on local wisdom with reference to the Indonesian Ulema Council halal tourism guidelines. …”
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Orphan G protein-coupled receptor GPRC5B controls macrophage function by facilitating prostaglandin E receptor 2 signaling by Jeonghyeon Kwon, Haruya Kawase, Kenny Mattonet, Stefan Guenther, Lisa Hahnefeld, Jamal Shamsara, Jan Heering, Michael Kurz, Sina Kirchhofer, Cornelius Krasel, Michaela Ulrich, Margherita Persechino, Sripriya Murthy, Cesare Orlandi, Christian D. Sadik, Gerd Geisslinger, Moritz Bünemann, Peter Kolb, Stefan Offermanns, Nina Wettschureck

“…Abstract Macrophages express numerous G protein-coupled receptors (GPCRs) that regulate adhesion, migration, and activation, but the function of orphan receptor GPRC5B in macrophages is unknown. …”
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Plasma membrane and nuclear phosphatidylinositol 4,5-bisphosphate signalling in cancer by Agnieszka Chytła, Stephanie Rattay, Baki Akgül, Martin Sztacho

“…Nuclear phosphoinositides, particularly PI(4,5)P2, are essential for regulating transcription factors and chromatin organisation, thereby shaping gene expression patterns. …”
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Inducers of Autophagy and Cell Death: Focus on Copper Metabolism by Weikang Ling, Shuo Li, Yang Zhu, Xin Wang, Dongmei Jiang, Bo Kang

“…Furthermore, autophagy may be activated by a disruption in copper homeostasis, while it plays a dual role in regulating copper-induced cell death by acting both as an inhibitor of cell death and as a promoter of cytotoxicity. …”
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Development of path reservation for wheelchair users within a High-Activity train Station: A case study of SRT Red Line, Don Mueang Station, Bangkok, Thailand by Pakapon Ueasatchamongkhon, Somsiri Siewwuttanagul

“…The results contribute to the existing knowledge by giving an in-depth comprehension of the role of path reservation based on spatial-based accessibility and legal standards and regulations in improving circulation within the station. …”
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Dimethyl fumarate promotes the degradation of HNF1B and suppresses the progression of clear cell renal cell carcinoma by Yue Dai, Hongchen Li, Shiyin Fan, Kai Wang, Ziyi Cui, Xinyu Zhao, Xue Sun, Mingen Lin, Jiaxi Li, Yi Gao, Ziyin Tian, Hui Yang, Bingbing Zha, Lei Lv, Yanping Xu

“…In summary, we provide evidences supporting DMF as a potential drug for clinical treatment of ccRCC by targeting HNF1B and reveal a previously unrecognized role of HNF1B in regulating YAP in ccRCC.…”
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Integrated transcriptomic and metabolomic analyses reveal critical gene regulatory network in response to drought stress in Dendrobium nobile Lindl by Chaoyan Lv, Ya He, Zaiqian Jiang, Wenjia Hu, Mei Zhang

“…Conclusions The results showed that arginine and proline metabolism, glucosinolate biosynthesis and tyrosine metabolism pathways participated in regulating drought stress in D. nobile Lindl. Our study provides a theoretical basis for studying the drought resistance mechanisms in Dendrobium.…”
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Dipropyl phthalate induces craniofacial chondrogenic defects in zebrafish embryos by Qinyuan Shen, Weitao Hu, Fasheng Liu, Si Dong, Xinya Peng, Yihang Zhong, Chao Chen, Yuhua Zuo, Chenkai Ge, Weirong Li, Wenwen Zha, Zhijun Ye, Zigang Cao, Lan Liao

“…Transcriptome sequencing and molecular docking analyses revealed that DPRP down-regulated chondrocyte-related genes and induced activation of the FoxO signaling pathway, which in turn interfered with cell proliferation and apoptosis. …”
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The integrated management system in the bakery industry of Leskovac by Veličković Jasmina, Arsić Jovana, Staletović Maja

“…In order to get high quality and safe, short-lived and semi-permanent products, apart from the use of regulated and standardized equipment, that is, the procedures of quality systems ISO 9001:2015, it is necessary to provide the food safety system (HACCP), which determines, evaluates and controls risks important for the safety of made products. …”
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XGBoost-enhanced ensemble model using discriminative hybrid features for the prediction of sumoylation sites by Salman Khan, Sumaiya Noor, Tahir Javed, Afshan Naseem, Fahad Aslam, Salman A. AlQahtani, Nijad Ahmad

“…Abstract Posttranslational modifications (PTMs) are essential for regulating protein localization and stability, significantly affecting gene expression, biological functions, and genome replication. …”
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