Resveratrol, a food-derived polyphenol, promotes Melanosomal degradation in skin fibroblasts through coordinated activation of autophagy, lysosomal, and antioxidant pathways by Saki Okamoto, Saya Kakimaru, Mayuko Koreishi, Mika Sakamoto, Yoshimasa Nakamura, Hideya Ando, Yoshio Tsujino, Ayano Satoh

“…Furthermore, reporter assays showed resveratrol's activation of antioxidant response via nuclear factor erythroid 2-related factor 2 (NRF2)-mediated, leading to upregulation of transcription factor EB/transcription factor E3 (TFEB/TFE3), master regulators of lysosomal function. In fibroblasts pre-loaded with melanosomes, resveratrol reduced melanosome content compared to control by day 3. …”
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Techniques for Suppressing Mineral Dust Aerosol from Raw Material Stockpiles and Open Pit Mines: A Review by Hsin-Chieh Kung, Wan-Ching Lin, Bo-Wun Huang, Justus Kavita Mutuku, Guo-Ping Chang-Chien

“…Industries with notable mineral dust production capture and suppress dust using dry and wet techniques to curb nuisance and attain air quality regulations. Wet techniques are more versatile than dry methods for large stockpiles requiring constant loading and offloading. …”
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WNT11 Promotes immune evasion and resistance to Anti-PD-1 therapy in liver metastasis by Weiliang Jiang, Bingjie Guan, Hongcheng Sun, Yushuai Mi, Sanjun Cai, Rong Wan, Xinxiang Li, Peng Lian, Dawei Li, Senlin Zhao

“…Our findings highlight WNT11/CAMKII axis as a critical regulator of the TME and a promising target for immunotherapy in patients with LM.…”
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Targeting adipocyte ESRRA promotes osteogenesis and vascular formation in adipocyte-rich bone marrow by Tongling Huang, Zhaocheng Lu, Zihui Wang, Lixin Cheng, Lu Gao, Jun Gao, Ning Zhang, Chang-An Geng, Xiaoli Zhao, Huaiyu Wang, Chi-Wai Wong, Kelvin W. K. Yeung, Haobo Pan, William Weijia Lu, Min Guan

“…Estrogen-related receptor α (ESRRA) is a key regulator responding to metabolic stress. Here, we show that adipocyte-specific ESRRA deficiency preserves osteogenesis and vascular formation in adipocyte-rich bone marrow upon estrogen deficiency or obesity. …”
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The Influence of Pro Evolution Soccer Game-Based Learning on Understanding Football Rules among Tenth Grade Students by Irvan Abdillah, Samsuddin Siregar, Rafael Burgueño, Felisa Romo Lea, Gertude Barton

“…This research endeavors to examine the influence of Pro Evolution Soccer on the understanding of Soccer regulations among tenth-grade students at SMA Dharma Pancasila Medan. …”
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Peripheral membrane protein endophilin B1 probes, perturbs and permeabilizes lipid bilayers by Arni Thorlacius, Maksim Rulev, Oscar Sundberg, Anna Sundborger-Lunna

“…Abstract Bin/Amphiphysin/Rvs167 (BAR) domain containing proteins are peripheral membrane proteins that regulate intracellular membrane curvature. BAR protein endophilin B1 plays a key role in multiple cellular processes critical for oncogenesis, including autophagy and apoptosis. …”
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Weakened future surface warming in China due to national planned afforestation through biophysical feedback by Shuaifeng Song, Xiaodong Yan, Xuezhen Zhang, Zhibo Gao, Wenqiang Xie

“…Here, using the Weather Research and Forecast model (WRF) nested by the bias-corrected MPI-ESM1-2-HR model, we simulated how future afforestation regulated the land surface temperature (LST) in China. …”
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Design and Pro-typing of an Electronic Coil Winding Machine. by Arinaitwe, Joel

“…This allows for: Precise Control: The encoder data can be used by a control system to precisely regulate the speed and direction of the winding spindle, ensuring consistent coil geometries. …”
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Phages as potential life-saving therapeutic option in the treatment of multidrug-resistant urinary tract infections by Beata Zalewska-Piątek, Michalina Nagórka

“…The aim of this review is to present issues related to the use of phages in the treatment of UTIs of various etiological origins in selected patients, including those with comorbidities, taking into account the legal regulations, safety and effectiveness of this experimental therapy. …”
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Consideraciones sobre la regulación jurídica ambiental de los servicios ecosistémicos en Argentina by Clara María Minaverry

“…Una de las limitaciones para el caso de Argentina, es que no se dictó una norma específica que regule a los servicios ambientales. Podemos concluir que en la normativa de los otros países de la región que cuentan con leyes sobre pago por servicios ecosistémicos, se pueden encontrar algunos aspectos de relevancia que podrían ser tenidos en cuenta para una futura norma jurídica y/o políticas públicas en Argentina.…”
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IMPACT OF GENDER DIVERSITY ON TAX COMPLIANCE OF NON-FINANCIAL LISTED COMPANIES IN NIGERIA by Mathias Gboyega OGUNDEJI

“…This study employs explanatory sequential design of mixed method to analyse and interpret the quantitative and qualitative data set. 68 out of 116 non-financial listed companies from 2004 to 2018 were selected as the final sample based on data availability while qualitative data was obtained through semi structured interviews on 17 corporate governance agents (Board of Directors; Key Executive Management; Partners of the big four audit companies; Academic Scholars; Regulators; Tax Consultants; and Shareholders). A Generalised Least Squares Regression and Discourse analysis were used to analyse the quantitative and qualitative data respectively. …”
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Host plants selection of Centranthera grandiflora Benth. and nontargeted metabolomics analysis of its parasitic and non-parasitic samples. by Song Jin, Yuchuan Li, Jun Ni, Haili Xie, Falin Lei, He Liu

“…Analysis of the 37 pathways in combination with the differential metabolites showed that in addition to being involved in the synthesis pathway of iridoid terpenes, the up-regulated metabolites of parasitized plants were involved in the synthesis pathways of several functional components, while that of non-parasitic plants were involved in the subsequent catabolism of monoterpenoid compounds, as well as the metabolic pathways of nutrients synthesis and catabolism, energy generation, and phytohormone production required for plant growth.…”
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Salário de docente básico by Pedro Demo

“…Therefore, the recent proposal of 40 working hours per week and a basic salary of R$ 950,00 seems to be very unsatisfactory, as it cannot regulate teachers' work time preferably in eight hours daily. …”
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Validity of legal norms with special reference to Kelsen's general theory of law by Pajić-Šavija Sandra

“…The term validity of legal norms usually means the obligation of legal norms for entities whose behavior is regulated by a legal norm. In legal theory, the concept of validity of law is used in a different sense. …”
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A framework to guide future farming research with Indigenous communities by Daniel Hayden, Amber Hayden

“…Researchers should be aware of the implications of research in Indigenous communi­ties, involving the cultural boundaries associated with crops and seeds, which are often not regulated and thus warrant protection. As Western science seeks to find sustainable alternatives to current farming norms, as seen in other areas of land man­agement, we encourage creating shared learning environments between researchers and Indigenous Peoples to foster relevant and equitable outcomes for farming practices. …”
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Pilot study on the effects of assertion video viewing and physical activity on depressive symptoms in workers witnessing workplace bullying by Atsuo Hattori, Yasumasa Otsuka

“…Consequently, companies in Japan were legally obligated to implement the necessary employment management regulations to prevent workplace bullying in 2019. Notably, assertion and physical activities can reduce depressive symptoms. …”
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Understanding the impact of triazoles on female fertility and embryo development: Mechanisms and implications by Sonal Sharma, Geeta Pandey

“…Triazoles are among the most widely used fungicides that were launched in 1980s and are one of the most important pesticide groups used in agriculture as plant growth regulators and stress protectors. Triazoles are also frequently used in the pharmaceutical industry to treat fungal and bacterial infections as well as to treat and prevent some forms of pneumonia. …”
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DYNAMICS OF AFRICAN TRADITIONAL AND CULTURAL PRACTICE AS A SOCIAL CONTROL MECHANISM: A DETERRENT THEORETICAL ANALYSIS ON THE ALEKWU BELIEF SYSTEM AMONG THE IDOMA PEOPLE IN NIGERIA by Daniel, Rosemary Onchi

“…Traditional and cultural customs in Africa have long been used as a form of social control mechanism which is known for regulating conduct and preserving community peace. The Alekwu belief system is one such tradition that is firmly ingrained in the Idoma community of Nigeria. …”
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ILO Convenstions and Migrant Workers: Construction of Protection in National Labor Law by Shohib Muslim, Khrisna Hadiwinata, Rizqi Khoirunnisa, Shinta Hadiyantina, Zainal Amin Ayub

“…The International Labor Organization has clearly regulated that human rights such as the right to work must be upheld and guaranteed. …”
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PUBLIC AWARENESS OF DEPOSIT INSURANCE AND INVESTOR COMPENSATION SCHEMES IN BULGARIA by Irina Kazandzhieva, Elena Ralinska

“…The results of the survey provide information that the efforts of the regulators and financial safety net schemes should be directed to increasing the awareness of depositors and investors in Bulgaria about the benefits and limitations of both schemes. …”
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