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2441
Toxicological effects of the environmental pollutant perfluoronanoic acid on the ground-dwelling arthropod Solenopsis invicta
Published 2025-01-01“…Perfluorononanoic acid (PFNA), widely employed in surfactants, coatings, plastics, corrosion inhibitors, and fire-extinguishing agents, is less regulated than PFOS or PFOA but displays higher bioaccumulation and potential toxicity. …”
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2442
Bee Venom—A Potential Complementary Medicine Candidate for SARS-CoV-2 Infections
Published 2021“…Melittin is associated with the underexpression of proinflammatory cytokines, including nuclear factor-kappa B (NF-kB), extracellular signal-regulated kinases (ERK1/2), and protein kinase Akt. …”
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2443
EFFECT OF AUDIT QUALITY ATTRIBUTES AND IFRS ADOPTION ON FINANCIAL REPORTING QUALITY OF LISTED MANUFACTURING FIRMS IN NIGERIA
Published 2024-10-01“…Hence, the study recommends the enhancing the implementation and oversight of IFRS standards and ensuring that the regulations are not only adhered to but also comprehensively understood, and any unintended consequences are mitigated. …”
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2444
Mitigating drought stress in fenugreek through synergistic effects of alanine and potassium-enriched biochar
Published 2025-02-01“…Furthermore, the enrichment of potassium (K) in biochar also increases its availability to plants, directly regulating the stomatal conductance to alleviate drought stress. …”
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2445
The Managers' Perceptions of Telework Implementation Requirements in the Algerian Companies: A Post Covid-19 Assessment
Published 2025-02-01“…Findings: The results concluded that accelerating the telework implementation in Algerian company requires, firstly, the legislative framework by reviewing the labor law that regulates and documents the existing relationship between the teleworker and the employer, and also consistent with the developments of the current situation, and secondly to, the presence of digital infrastructure that goes beyond the need for designated places to include the presence of a wide-coverage, protected, and high-flow communication network, meaning preparing the primary environment with basic equipment and software, thirdly, the existence of training program in order to help to make the best use of information technology (ICT) and reduces the need for supervision and follow-up. …”
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2446
Preterm nutrition and brain development
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2447
The position of Lithuanian parties towards Poland in 1920-1926: from modus vivendi to permanent confrontation
Published 2008-08-01“…Unsuccessful attempts to regulate the conflict with Poland in a pacific way and to regain the historical capital made the leaders of the state's political parties choose a state of permanent confrontation with Poland and seek support to ensure the safe existence of the state from the Soviet Union and Germany. …”
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2448
SLC7A11 is a potential therapeutic target and prognostic biomarker correlated with immune cell infiltration in cervical cancer
Published 2025-02-01“…Besides, SLC7A11 was positively regulated cervical cancer cells’ proliferation, migration and invasion. …”
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2449
Maximizing tuberculosis services through private provider engagement – A case study from Pakistan
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2450
Wnt/β-catenin signalling underpins juvenile Fasciola hepatica growth and development.
Published 2025-02-01“…FISH-mediated transcript localisation revealed partitioning of the five Wnt ligands, with each displaying a distinct expression pattern, consistent with each Wnt regulating the development of different cell/tissue types. …”
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2451
Continuous Improvements and Future Challenges of Air Pollution Control at an Advanced Semiconductor Fab
Published 2023-04-01“…This effective strategy employs a two-stage treatment method to comply with national emission regulations. Eight different types of local scrubbers (typ. gas flow rate: 0.3–2.0 CMM for the dry type or 60–83.3 CMM for the wet type) are used as pre-treatment devices at the first stage to remove specific target pollutants with high concentrations emitted from process chambers. …”
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2452
Coupling relationship between land use transition and rural transformation development: A case study of county-level regions in Jiangsu Province
Published 2025-01-01“…[Conclusion] The coupling relationship between land use transition and rural transformation development determines the internal dynamics of regional rural transformation, and regulating this relationship provides an effective path for optimizing the rural spatial governance system and promoting sustainable rural development.…”
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2453
Ginkgetin delays the progression of osteoarthritis by inhibiting the NF-κB and MAPK signaling pathways
Published 2025-02-01“…Results Network pharmacology has revealed that GK regulates OA via several key pathways, especially NF-κB, HIF-1, PI3K-AKT, and substances like reactive oxygen species. …”
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2454
Potential improvement in spatial accessibility of methadone treatment with integration into other outpatient substance use disorder treatment programs, New York City, 2024.
Published 2025-01-01“…<h4>Background</h4>Methadone is an effective treatment for opioid use disorder; however, its provision in the US is limited to federally-regulated opioid treatment programs (OTP). Expansion of methadone treatment into non-OTP substance use disorder (SUD) treatment programs ('expanded methadone treatment access') is a promising intervention to increase access.…”
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2455
Optimizing therapeutic outcomes: preconditioning strategies for MSC-derived extracellular vesicles
Published 2025-02-01“…Additionally, miRNA variability in MSC-EVs presents challenges due to the diverse roles of miRNAs play in regulating gene expression and cell behavior. The miRNA content of MSC-EVs can be influenced by preconditioning strategies and differences in isolation and purification methods, which may alter the expression profiles of specific miRNAs, contributing to differences in their therapeutic effects.…”
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2456
A bidirectional Mendelian randomization study integrating genome-wide association studies, expression quantitative trait locus, and methylation quantitative trait locus data reveal...
Published 2025-02-01“…By incorporating consistent summary data-based Mendelian randomization associations between DNA methylation and smoke/Barrett’s esophagus, gene expression and smoke/Barrett’s esophagus, and DNA methylation and gene expression, we identified that the genetic variant-cg00935895-RBM43 (ENSG00000184898)-smoke/Barrett’s esophagus axis exerted an effect on smoke/Barrett’s esophagus by altering the DNA methylation level, which regulated the expression level of RBM43. Conclusions: Our study provides evidence of a bidirectional causal association between smoking and Barrett’s esophagus from a genetic perspective, which sheds new light on the potential role of RBM43 as a mediator in facilitating the impact of smoking and Barrett’s esophagus.…”
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2457
Resetting the Hsc70-mediated lysosomal degradation of PD-L1 via a supramolecular meso peptide for the restoration of acquired anti-tumor T cell immunity
Published 2025-02-01“…Overall, this work not only presents an alternative approach for targeting PD-L1-dependent cancer immune evasion, but also provides a modularized strategy for discovering specific regulators for target proteins in various diseases.…”
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2458
THE IMPACT OF FIRM CHARACTERISTICS ON ACCRUALS AND REAL EARNINGS MANGEMENT OF LISTED MANUFACTURING FIRMS IN NIGERIA
Published 2024-10-01“…Therefore, this study recommends heightened oversight and transparency, particularly in the context of real earnings management; regulators can work towards curbing detrimental practices that impact firm value. …”
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2459
Sustainable PV-hydrogen-storage microgrid energy management using a hierarchical economic model predictive control framework
Published 2025-02-01“…Under the proposed framework, a mixed-integer nonlinear optimization problem is solved by the long-term EMPC in the upper level to regulate the start-up/shut-down of hydrogen devices and the state of charge in the battery, and the short-term EMPC in the lower level reoptimizes the power demand tracking cost while tracking the optimal reference signal from the long-term EMPC, thereby improving overall control system efficiency. …”
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2460
An Interactive Clustering-Based Visualization Tool for Air Quality Data Analysis
Published 2023-10-01“…., fireworks and traffic regulations, school closures) as well as longer-term decision-making (e.g., transport control stations, fuel permits, old vehicle replacement, fuel type).…”
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