Bacterial nanocellulose and its oxidized form as functional carriers for pomegranate peel extract: A sustainable approach to bioactive delivery by Vuk Filipovic, Jasmina Nikodinovic-Runic, Katarina Savikin, Jelena Zivkovic, Jelena Mudric, Nemanja Krgovic, Marijana Ponjavic

“…Antioxidant activity was evaluated by DPPH and FRAP assays, while the α-glucosidase inhibition assay was used to assess the ability to slow carbohydrate digestion, which helps regulate blood sugar levels. The o-BNC-PPE formulation exhibited significantly higher antioxidant activity than BNC-PPE, attributed to its richer phenolic content. …”
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Endoplasmic reticulum stress-related CLIP4 plays a procarcinogenic role in hepatocellular carcinoma: an integrated analysis by Anqi Wang, Sitong Yan, Weijia Jiang, Xiang Chen, Yuhan Huang, Xiangyu Zu, Xiao Du, Lulu Fan, Jiatao Liu, Guoping Sun

“…Conclusions CLIP4 is a potential immune-related oncogenic molecule in HCC. ERS regulates the expression of CLIP4, and CLIP4 promotes the proliferation, migration, and EMT of HCC cells.…”
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Methanotroph-methylotroph lipid adaptations to changing environmental conditions by Nora Richter, Laura Villanueva, Laura Villanueva, Ellen C. Hopmans, Nicole J. Bale, Jaap S. Sinninghe Damsté, Jaap S. Sinninghe Damsté, Darci Rush

“…Methanotrophs, in particular methane-oxidizing bacteria (MOB), regulate the release of methane from lakes, and often co-occur with methylotrophs that may enhance methane-oxidation rates. …”
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Incorporating insulin into alginate-chitosan 3D-printed scaffolds: A comprehensive study on structure, mechanics, and biocompatibility for cartilage tissue engineering by Afsaneh Jahani, Mohammad Sadegh Nourbakhsh, Ali Moradi, Marzieh Mohammadi, Lobat Tayebi

“…This research aims to develop to yield mechanically optimized, bioactive 3D-printed scaffolds for regulated delivery of Insulin to promote cartilage regeneration.…”
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Effectiveness of educational interventions to promote safe handling of pesticides: protocol for a systematic review and meta-analysis by Anne Cockcroft, Neil Andersson, Sergio Paredes-Solís, José Legorreta-Soberanis, Belén Madeline Sánchez-Gervacio, Víctor Manuel Alvarado-Castro, Miguel Flores-Moreno, Claudia Erika Rios-Rivera, Janet Saldaña-Almazán

“…Introduction Appropriate use of pesticides minimises harm to human health and the environment. Despite regulations and restrictions on use, however, many farmers still use highly toxic pesticides in ways that endanger their health and the environment. …”
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Connections Across Open Water: A Bi‐Organelle, Genomics‐Scale Assessment of Atlantic‐Wide Population Dynamics in a Pelagic, Endangered Apex Predator Shark (Isurus oxyrinchus) by Andrea M. Bernard, Marissa R. Mehlrose, Kimberly A. Finnegan, Bradley M. Wetherbee, Mahmood S. Shivji

“…ABSTRACT Large‐bodied pelagic sharks are key regulators of oceanic ecosystem stability, but highly impacted by severe overfishing. …”
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Unraveling the depth-dependent causal dynamics of methanogenesis and methanotrophy in a high-latitude fen peatland by Shuai Yang, Jinyun Tang, Zhen Li, Kunxiaojia Yuan, Qiong Wu, Kuang-Yu Chang, Suzanne B Hodgkins, Rachel M Wilson, Qing Zhu, Robert F Grant, William J Riley, Scott R Saleska, Virginia I Rich, Ruth K Varner

“…Next, to explore the vertical heterogeneity in CH _4 cycling, we applied the PCMCI/PCMCI+ causal detection framework with a bootstrap aggregation method to the modeling results, characterizing causal relationships among regulating factors (e.g. temperature, microbial biomass, soil substrate concentrations) through acetoclastic methanogenesis, hydrogenotrophic methanogenesis, and methanotrophy, across three depth intervals (0–10 cm, 10–20 cm, 20–30 cm). …”
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Eucalyptus grandis WRKY genes provide insight into the role of arbuscular mycorrhizal symbiosis in defense against Ralstonia solanacearum by Jianlang Zhang, Xinzhu Yang, Chunyu Huo, Xinyi Fan, Qiutong Liu, Zhihong Liu, Yu Su, Zujing Chen, Zujing Chen

“…Several genes (including EgWRKY116, EgWRKY62, and EgWRKY107) were significantly induced by Ri; these genes might enhance the defense of E. grandis against Rs.DiscussionTherefore, we identified E. grandis WRKY genes that are regulated by AMF colonization, some of which might improve the defense of E. grandis against R. solanacearum. …”
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Preliminary exploration of mRNA, lncRNA, and miRNA expressions in the bovine jejunum unveils novel aspects of Mycobacterium avium subspecies paratuberculosis infections by Yahui Gao, Jie Cao, Bo Han, Dongxiao Sun

“…Our results demonstrated that not only mRNAs but also lncRNAs and miRNAs played important roles in regulating MAP infection in dairy cattle. This study provided a valuable resource for understanding the molecular basis of JD, potentially contributing to the genetic improvement of JD resistance in dairy cattle.…”
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An Ontology for Digital Medicine Outcomes: Development of the Digital Medicine Outcomes Value Set (DOVeS) by Benjamin Rosner, Matthew Horridge, Guillen Austria, Tiffany Lee, Andrew Auerbach

“…An outcomes-based DHT ontology could therefore be valuable not only for health systems seeking to evaluate tools that influence certain outcomes, but also for regulators and vendors seeking to ascertain potential substantial equivalence to predicate devices. …”
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The sphingosine‐1‐phosphate signaling pathway (sphingosine‐1‐phosphate and its receptor, sphingosine kinase) and epilepsy by Lin Wang, Qingxia Kong, Xinyi Leng, Howan Leung, Yang Li

“…Plain Language Summary This article combines the latest research literature at home and abroad to review the sphingosine 1‐phosphate signaling pathway and epileptogenesis, drug‐resistant epilepsy, epilepsy comorbidities, other diseases that can cause epilepsy, as well as the sphingosine‐1‐phosphate signaling pathway regulators and epilepsy, with the expectation of providing a certain theoretical basis for finding potential epilepsy treatment targets and/or epileptogenic biomarkers in the sphingosine‐1‐phosphate signaling pathway.…”
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BTEX Exposure Assessment and Inhalation Health Risks to Traffic Policemen in the Klang Valley Region, Malaysia by Noor Fatihah Mohamad Fandi, Juliana Jalaludin, Mohd Talib Latif, Haris Hafizal Abd Hamid, Mohd Fairus Awang

“…These results, which provide baseline data for determining the occupational risk to individuals who are exposed to BTEX while working on or near a road, emphasize the need for additional regulations, including the use of appropriate respiratory protective equipment.…”
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Beyond the screen: Exploring the dynamics of social media influencers, digital food marketing, and gendered influences on adolescent diets. by Ashley Amson, Mariangela Bagnato, Lauren Remedios, Meghan Pritchard, Soulene Sabir, Grace Gillis, Elise Pauzé, Christine White, Lana Vanderlee, David Hammond, Monique Potvin Kent

“…Policy efforts should focus on regulating unhealthy food marketing, addressing gender-specific targeting, and fostering a healthy social media environment for adolescents to support healthier dietary patterns.…”
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Bioinformatics screening and clinical validation of CircRNA and related miRNA in male osteoporosis by Jiayi Li, Sijia Guo, Qingyun Sun, Ning An, Jisheng Lin, Qi Fei

“…Conclusion We emphasized the roles of several significantly up- and down-regulated circRNAs and four circRNAs derived from three hub genes in male osteoporosis. …”
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Book spreaders in the towns of Samogitian principality in the XVIII century by Elmantas Meilus

“…For this reason, in 1743, the Samogitian bishop Antanas Tiškevičius banned the free book trade in his diocese and commissioned Juozas Stripeika and Martynas Maulevičius, living in Kražiai, with the task of regulating book selling. Antanas Tiškevičius' circular provides the following information: 1. …”
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Impact of COVID-19 on the Air Quality over China and India Using Long-term (2009–2020) Multi-satellite Data by Manish Soni, Sunita Verma, Hiren Jethava, Swagata Payra, Lok Lamsal, Priyanshu Gupta, Janhavi Singh

“…Over the SE and NE China, both NO2 and SO2 levels decreased dramatically in 2020 from that of 2009–19, by more than 40% and 65%, respectively, because of both stricter regulations of emissions and less traffic activity due to reduced social and industrial activities during COVID-19 restrictions. …”
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Assessing Lung and Skin Cancer Risks for Steel and Iron Manufacturing Industry Workers Exposed to Polycyclic Aromatic Hydrocarbons by Ying-Fang Wang, Yu-Chieh Kuo, Ming-Yeng Lin, Perng-Jy Tsai

“…The mean inhalatory exposure concentrations of the melting and casting workers (2.84 × 104–3.32 × 104 ng m−3) were higher, but ladling workers (1.58 × 105 ng m−3) were lower, than the time-weighted average permissible exposure level (PEL-TWA) regulated in Taiwan (1.00 × 105 ng m−3). The estimated lifetime excessive lung cancer risks for the latter (2.09 × 10−3) were lower than that of the former (3.43 × 10-3–8.84 × 10−3), they were all higher than the significant risk (10−3) defined by the US Supreme Court. …”
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Designing a Digital Transformation Model in the Offshore Oil and Gas Industry in Iran by Saeid Noadoust, Mostafa Safdari Ranjbar

“…Also, promoting an organizational culture based on the adoption of digital technologies at industry and national levels via establishing stringent environmental and safety regulations for personnel who work on offshore platforms and supporting investment in digital transformation in the oil and gas industry can help with reaching the set targets.   …”
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Dietary and plasma atherogenic and thrombogenic indices and cardiometabolic risk factors among overweight and individuals with obesity by Reyhaneh Mokhtari, Mahdieh Abbasalizad Farhangi

“…Conclusion This research introduces a novel field of investigation and emphasizes the possible importance of TI, AI, and AIP indices in regulating cardiometabolic risk factors.…”
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Spatial and seasonal distribution of selected nitrogen cycle genes in deep waters of the Baltic Proper by Michał Grabski, Michał Grabski, Ewa Kotlarska, Aneta Łuczkiewicz, Konrad Hryniewicz, Grzegorz Węgrzyn, Beata Szymczycha

“…Marine nitrogen cycle ultimately depends on the biological responses of oceanic microbial communities. It indirectly regulates primary production and influences the strength of the biological pump, which contributes to the oceanic uptake of atmospheric carbon dioxide (CO2). …”
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