Metabolic and Genetic Determinants of Lipid Metabolism Disruption in Non-Alcoholic Fatty Liver Disease by O. Yu. Kytikova, T. P. Novgorodtseva, Yu. K. Denisenko, D. A. Kovalevsky

“…Further research into the NAFLD genetic mechanisms regulating the metabolism of fatty acids appears to be promising for a deeper understanding of the pathogenesis of this multifactorial disease.…”
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A new sliding mode control strategy to improve active power management in a laboratory scale microgrid by Oscar Gonzales-Zurita, Jean-Michel Clairand, Guillermo Escrivá-Escrivá

“…Most SPVSIs on the market use proportional–integral (PI) control for their closed-loop regulation process. Although the PI controller represents an effective method for power management in a microgrid, it exhibits challenges in achieving proper system response and stability for active power generation. …”
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Metabolic rate and insulin-independent glucose uptake increase in a TDP-43Q331K mouse model of amyotrophic lateral sclerosis by Tanya S. McDonald, Cedric S. Cui, Titaya Lerskiatiphanich, Jianina Marallag, John D. Lee

“…Impaired glucose regulation is increasingly recognised in amyotrophic lateral sclerosis (ALS), yet the precise mechanisms remain unclear. …”
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Pathogenesis of Functional Biliary Pain and Pharmacology of Trimebutin by E. L. Bueverova, O. Yu. Zolnikova, N. L. Dzhakhaya, A. V. Sedova, V. Т. Ivashkin

“…In the multilevel system of regulation of the gallbladder and sphincter apparatus, the opioid system occupies a special place. …”
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Innovation of kwetiau with red rice and red bean flour: evaluation of nutritional value and potential fiber source for patients with diabetes mellitus by Mulus Gumilar, Gurid Pramintarto Eko Mulyo, Dila Evianda, Roro Nur Fauziyah

“…Dietary fiber can help delay carbohydrates conversion to glucose, slow the rise in blood sugar, and aid in blood sugar regulation. This study aimed to evaluate the effects of red rice flour and red bean flour formulations on the sensory characteristics, fiber content, and nutritional value of kwetiau. …”
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Clinical and Morphological Manifestations of Gastritis and Serum Cytokine Levels in Schoolchildren with Familial History of Gastric Cancer by T. V. Polivanova, E. V. Kasparov, V. A. Vshivkov

“…In positive history and negative H. pylori tests, the cell immune response regulator IL-18 37 was revealed elevated in histology. …”
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The Multi-Level Governance Dilemma in Mandalika Special Economic Zone: A Bargaining and Cooperation Approach by Roseno Aji Affandi, Salsa Nabila Putri, Tirta Nugraha Mursitama, Yanyan Mochamad Yani, Arry Bainus

“…The research concluded that the main problems in SEZ development stemmed from three main factors: (1) lack of comprehension of multi-level governance, both from the central and local governments; (2) too-centralized government imposing top-down regulation; (3) lack of skills from the local government and local community to negotiate and collaborate with the multi-stakeholders. …”
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Action Plans to Reduce PM2.5 Concentrations in Hotspots of Delhi-NCR Using a One-way Coupled Modeling Approach by Shubham Sharma, Mukesh Khare, Sri Harsha Kota

“…A marginal reduction of 4% estimated for the previously implemented traffic rationing measure, the odd-even rule, indicates that such regulation of vehicles alone might be inefficacious. …”
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An elucidatory model of oxygen's partial pressure inside substomatal cavities by A. S. Kowalski, A. S. Kowalski

“…At very high leaf temperatures, mass flow also influences transport of water vapour and carbon dioxide, physically decoupling their exchanges and reducing water-use efficiency, independently of stomatal regulation.</p>…”
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Natural selection and adaptive traits in the Maniq, a nomadic hunter-gatherer society from Mainland Southeast Asia by Tobias Herzog, Maximilian Larena, Wibhu Kutanan, Helmut Lukas, Martin Fieder, Helmut Schaschl

“…Genes under positive selection were enriched in pathways related to immunity, metabolic regulation, structural adaptation, cardiovascular performance, and neuromodulatory traits. …”
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Decoding vascular aging: implications for atherosclerosis progression and clinical intervention by Silumbwe Ceaser Wankumbu, Xiao-Man Ji, Ming Xu

“…In the review, we highlighted five altered vascular mechanisms in cardiovascular models: genomic instability, neurohormonal deregulation, epigenetics, protein regulation, and the gut microbiome. The articles were selected from various indexed scientific databases. …”
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Phusis, proto-embrayage et bruits du corps by Denis Bertrand

“…Soupirs, ronflements, reniflements, rots, éternuements, toux, gargouillis, pets... nombreux sont les bruits du corps. Leur régulation est graduelle, à la fois personnelle – entre ceux que l’on contrôle et ceux que l’on ne contrôle pas – et collective – ils sont objets évolutifs d’acceptation sociale, de tolérance, de rejet ou d’interdit radical. …”
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A daily rhythm of cell proliferation in a songbird brain by Vladimira Hodova, Valentina Maresova, Rebecca Radic, Lubica Kubikova

“…This study may have implications for understanding the mechanisms underlying the daily regulation of brain cell proliferation in different species.…”
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Exploring Core Genes Associated with Sepsis and Systemic Inflammatory Response Syndrome Using Single-Cell Sequencing Technology by Shen Y, Leng L, Hu Y

“…The frequency of occurrence is on the rise, but there is a lack of certain indicators for the timely detection and recognition of illnesses.Methods: By virtue of scRNA-seq, this research has analyzed single-cell transcriptome data from samples taken from groups with septic death and systemic inflammatory response syndrome so as to identify the unique markers and patterns in immune response.Results: By revealing the status of twelve cell clusters of four major cell types in blood samples through UMAP cell clustering and the differences of major cell populations between the dead and SIRS patients, the results have elucidated the components of different cells and their marker genes in two disease states, and the response mechanism beneficial to disease diagnosis in blood samples.Conclusion: By establishing a theoretical framework centered on cellular and molecular regulation, the study has introduced a novel approach for diagnosing and treating sepsis death group and SIRS patients early, as well as differentiating and preventing these conditions.Keywords: sepsis, SIRS, single cell sequencing, biomarkers, single cell transcriptome…”
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Analysis of poisoning with OTC drugs for suicidal purposes among children and adolescents in Poland in the period 2012 - 2023 by Maria Kubicka, Paulina Polańska, Marta Gruszka, Martyna Zakrocka

“…Strengthening psychological support and implementing stricter regulation of OTC drugs are crucial to addressing the root causes of youth suicide attempts. …”
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Importance of the 5’ untranslated region for recombinant enzyme production in isolated Bacillus subtilis 007 by Jana Senger, Adriana Schulz, Ines Seitl, Martin Heider, Lutz Fischer

“…These findings underscored the crucial role of post-transcriptional regulation and emphasized mRNA stability as a key role in recombinant enzyme production in B. subtilis 007.…”
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Unraveling the PVTGlu-mPFCGlu circuit: A new frontier in chronic pain management for bone cancer pain by Liqun Duan, Qianliang Wang, Jianpeng Chen, Zelin Fan, Wenzhi Zhang, Jun Yan

“…These findings imply a pivotal role for the PVTGlu-mPFCGlu circuit in the regulation of chronic pain in BCP.…”
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Macrophage MST1 protects against schistosomiasis-induced liver fibrosis by promoting the PPARγ-CD36 pathway and suppressing NF-κB signaling. by Jianyang Li, Xinyuan Cai, Yan Yang, Yulin Mao, Lin Ding, Qian Xue, Xunhao Hu, Yan Huang, Cong Sui, Yuxia Zhang

“…Conversely, MST1 deletion leads to up-regulation of pro-inflammatory genes instead of fibrolytic genes in macrophages, accompanied by decreased expression of CD36 and impaired phagocytosis. …”
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AlphaFold-based AI docking reveals AMPK/SIRT1-TFEB pathway modulation by traditional Chinese medicine in metabolic-associated fatty liver disease by Lulu Zhang, Yi Zheng, Mingyan Shao, Aiping Chen, Meiyi Liu, Wenlong Sun, Tianxing Li, Yini Fang, Yang Dong, Shipeng Zhao, Hui Luo, Juan Feng, Qi Wang, Lingru Li, Yanfei Zheng

“…Moreover, cotreatment with AMPK inhibitor Compound C, the regulation of QGJZF on TFEB, SIRT1, autophagy-related protein levels, and lipid deposition were reversed. …”
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PIN2-mediated self-organizing transient auxin flow contributes to auxin maxima at the tip of Arabidopsis cotyledons by Patricio Pérez-Henríquez, Shingo Nagawa, Zhongchi Liu, Xue Pan, Marta Michniewicz, Wenxin Tang, Carolyn Rasmussen, Xinping Cui, Jaimie Van Norman, Lucia Strader, Zhenbiao Yang

“…The reduction of IAA levels results in PIN2 down-regulation and cessation of the auxin flow. Hence, our results elucidate a self-activating and self-terminating transient polar auxin transport system in cotyledons, contributing to the formation of localized auxin maxima that spatiotemporally coordinate pavement cell interdigitation.…”
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