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1281
Sedum alfredii Hance: A cadmium and zinc hyperaccumulating plant
Published 2025-01-01“…This also encourages studies on functional genes involved in metal transport, antioxidant, transcription regulation and stress response, providing candidates for genetic modification. …”
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1282
Grape stems as sources of tryptophan and selenium: Functional properties and antioxidant potential
Published 2025-02-01“…Tryptophan, selenium, and phenolic compounds, which regulate cognitive functions, protein and enzyme synthesis, and antioxidant processes, were analysed. …”
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1283
Genome-wide identification and expression analysis of ZF-HD family in sunflower (Helianthus annuus L.) under drought and salt stresses
Published 2025-02-01“…Conclusions Overall, this study enhances our comprehension of the function of ZF-HD genes in positive regulation of responsiveness to abiotic stress and provide key candidate genes for sunflower stress resistance breeding.…”
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1284
The OXT rs6133010 variant modulates susceptibility to psychiatric symptoms during withdrawal in patients with alcohol dependence
Published 2025-02-01“…Additionally, OXT may not directly act as an anxiolytic but instead regulates anxiety by modulating hostility.…”
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1285
Production of novel theranostic nano-vector based on superparamagnetic iron oxide nanoparticles/miR-497 targeting colorectal cancer
Published 2025-02-01“…Immunofluorescence was employed to confirm transfection of cells with miR-497@NPs, and the down- regulation of CTLA4 in HT29, and Caco2 cell lines. On the other hand, PDL1 showed a significant increase in colorectal cell lines (HT-29 and Caco-2) in response to mir497-5p@Nano treatment. …”
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1286
New Zealand policy experts’ appraisal of interventions to reduce smoking in young adults: a qualitative investigation
Published 2017-12-01“…Exceptions were social marketing campaigns and extending smoke-free regulations to include outdoor areas of cafes and bars, which participants saw as politically feasible and likely to be effective.Conclusions Our findings suggest the merit of an approach that combines social marketing with regulation that makes accessing and using tobacco less convenient for young adults; however, political barriers may limit the regulatory options available in the short term. …”
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1287
Dysbiosis and extraintestinal cancers
Published 2025-02-01“…The oncogenic cascade always engages in the disruption of hormonal regulation and inflammatory responses, the induction of genomic instability and mutations, and the dysregulation of adult stem cell proliferation. …”
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1288
Dyskryminacja dzieci pozamałżeńskich w ustawodawstwie cywilnym w Drugiej Rzeczypospolitej i próby jej przezwyciężenia w projektach kodyfikacyjnych
Published 2025-02-01“…The author initially analyzes the concept of an illegitimate child in district legislation in interwar Poland, then addresses the issue of the distinction in the category of illegitimate children, as well as the uniform regulation of their legal status in after partitions legislation. …”
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1289
Current molecular understanding of central nervous system schwannomas
Published 2025-02-01“…In addition to genetic alterations, research is also being conducted on gene expression and epigenetic regulation, with a focus on NF2 methylation and post-transcriptional silencing by micro RNA. …”
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1290
Effects of foliar spraying ABA on ultrastructure and photosynthesis of cotton leaves at bolling stage
Published 2025-01-01“…[Objective] The study aims to investigate the mechanism of different concentrations of abscisic acid (ABA) on the photosynthetic effect and ultrastructure of cotton leaves during the bolling stage, and provide a theoretical basis for the regulation of cotton ineffective water loss by ABA in southern Xinjiang. …”
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1291
Distinct roles of Constitutive Photomorphogenesis Protein 1 homolog (COP1) in human hepatocyte models
Published 2025-02-01“…Transcriptomic changes were consistent with perturbed metabolism in primary hepatocytes and HepG2 cells and impaired cell cycle regulation in HuH-7 cells. In HepG2 and primary hepatocytes but not in HuH-7 cells, COP1 suppression reduced the expression of important hepatic regulators and markers. …”
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1292
Functional Outcome of Mesenchymal Stem Cells Vs. Hyaluronic Acid in Knee Osteoarthritis Kellgren-Lawrence Grade I-III At 6-and 12-Months Follow-Up: A Meta-Analysis
Published 2023-10-01“…The highly differentiated MSC aids in tissue repair, regulation of immune response, and anti-inflammatory effect on knee osteoarthritis, including the chondrogenesis mechanism. …”
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1293
Deciphering the regulatory programs of RNA binding proteins in rheumatoid arthritis through single-cell transcriptome analysis
Published 2025-01-01“…Single-cell RNA sequencing (scRNA-seq) data from published datasets were obtained to investigate the expression and dysregulation of RNA-binding proteins (RBPs), which are critical for alternative mRNA splicing and translational control in rheumatoid arthritis (RA). How RBP regulation differs between RA and osteoarthritis (OA) was examined using RBP for single-cell sub-clustering. …”
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1294
Transcriptome-wide identification and characterization of WUSCHEL-related homeobox (WOX) gene family in Pinus yunnanensis
Published 2025-02-01“…Abstract WUSCHEL-related homeobox (WOX), a specific gene family in plants, plays a critical role during stem cell regulation, plant regeneration and upgrowth. However, our understanding of WOX functions in conifers is limited compared to angiosperms. …”
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1295
Usability Testing pada Simulator Media Pembelajaran Lalu Lintas Berbasis Android
Published 2021-03-01“…Abstract The lack of public awareness about traffic regulation is a cause of frequent traffic accidents in Indonesia. …”
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1296
Extracecellulr vesicles (EVs) microRNAs (miRNAs) derived from mesenchymal stem cells (MSCs) in osteoarthritis (OA); detailed role in pathogenesis and possible therapeutics
Published 2025-02-01“…These EVs have been shown to significantly influence the regulation of various physiological activities of cells in the joint cavity. …”
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1297
Influence of day and night temperature and carbon dioxide concentration on growth, yield, and quality of green butterhead and red oakleaf lettuce.
Published 2025-01-01“…Production of lettuce (Lactuca sativa) within vertical farms is an expanding segment of controlled environment agriculture-precise manipulation of environmental parameters including mean daily temperature (MDT) and carbon dioxide (CO2) concentration enables year-round production, alongside color, yield, and crop size regulation. Our objectives included 1) quantify how MDT and CO2 interact to influence lettuce growth, development, and quality; 2) model lettuce growth under several MDTs and CO2 concentrations. …”
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1298
Seed priming and abiotic stress tolerance in carrot: Unraveling the mechanisms of improved germination.
Published 2025-01-01“…The application of inhibitors highlighted the involvement of specific cellular processes in regulation of seed germination under stress. For instance, actinomycin D reduced germination by 40% under salinity stress. …”
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1299
Anaerobic metabolism promotes breast cancer survival via Histone-3 Lysine-18 lactylation mediating PPARD axis
Published 2025-02-01“…We utilized chromatin immunoprecipitation sequencing with H3K18la antibodies, transcriptomics of clinical BC samples, and proteomics and ATAC-seq analyses of in vivo tumors to identify the genes regulated by H3K18la and the transcription factor PPARD. qPCR and Western blot assays were used to detect expressions of molecules. …”
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1300
Principles to award learning achievements for lifelong learning in health using micro-credentials: an international Delphi study
Published 2025-02-01“…This research supports the efforts by UN agency representatives and experts in qualification systems, medical education, the health and care sector, regulation, and accreditation, to build foundations from which to launch normative work on the application of micro-credentials to award learning achievements for health and care workers. …”
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