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1341
Asini Corii Colla (Ejiao) as a health-care food and traditional Chinese medicine: A review of its chemical composition, pharmacological activity, quality control, modern applicatio...
Published 2025-02-01“…It offers a range of therapeutic benefits, including anti-anemia properties, immune regulation, hemostasis, anti-inflammatory effects, antioxidant activity, and antibacterial properties. …”
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1342
Fractional-order PID feedback synthesis controller including some external influences on insulin and glucose monitoring
Published 2025-02-01“…The innovations of this work include a fractional-order diabetes mellitus model that captures the biological memory and hereditary effects of glucose regulation under stress, and a fractional-order PID controller that offers greater stability and robustness compared to conventional controllers, particularly in managing adrenaline-induced hyperglycemia. …”
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1343
The promising role of nanopore sequencing in cancer diagnostics and treatment
Published 2025-04-01“…In the field of RNA research, nanopore sequencing proves invaluable in discerning differentially expressed transcripts, uncovering novel elements linked to transcriptional regulation, and identifying alternative splicing events and RNA modifications at the single-molecule level. …”
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1344
Pendekatan Soft System Methodology (SSM) untuk membangun SIMOKAUD Holistik Integratif
Published 2022-10-01“…Abstract The Government of Indonesia has issued Presidential Regulation Number 60 of 2013 concerning Integrative Holistic PAUD for use by early childhood schools which is used as a rule and guideline in carrying out PAUD work programs. …”
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1345
Quzhou Aurantii Fructus Flavonoids Ameliorate Inflammatory Responses, Intestinal Barrier Dysfunction in DSS-Induced Colitis by Modulating PI3K/AKT Signaling Pathway and Gut Microbi...
Published 2025-02-01“…The alterations in endogenous metabolites were detected by untargeted metabolomics, and their potential correlation with intestinal flora was then examined utilizing Spearman correlation analysis. Subsequently, the regulation of gut microbiome by QAFF was validated by fecal microbiota transplantation (FMT).Results: Eleven flavonoids, including Naringin and hesperidin, were initially identified from QAFF. …”
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1346
A hammerhead ribozyme selects mechanically stable conformations for catalysis against viral RNA
Published 2025-02-01“…Abstract Ribozymes, widely found in prokaryotes and eukaryotes, target nucleic acids and can be engineered as biotechnical tools or for gene regulation or immune therapy. Among them, hammerhead is the smallest and best characterized ribozyme. …”
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1347
Microplastics: A threat to Fetoplacental unit and Reproductive systems
Published 2025-06-01“…The placenta has limited detoxifying capabilities and unique immunological regulation, making it especially sensitive to foreign particles. …”
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1348
New insights into the mechanism of triphenyl phosphate and its metabolite diphenyl phosphate in diabetic kidney disease
Published 2025-02-01“…The results indicated statistically significant regulation of most core targets by TPHP and DPHP in MPC5, MES13, and human kidney-2 cells.…”
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1349
Foliar spraying melatonin reduces the threat of chromium-contaminated water to wheat production by improving photosynthesis, limiting Cr translocation and reducing oxidative stress
Published 2025-01-01“…Furthermore, MT application enhanced transcriptional regulation, alleviated oxidative stress by boosting antioxidant enzyme activities, and restricted Cr translocation from roots to leaves and grains by increasing the accumulation of secondary metabolites, such as lignin and metallothionein. …”
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1350
Desregulación emocional en población con TDAH; una aproximación teórica/Emotional dysregulation in the population with ADHD. A Theoretical Approach
Published 2019-06-01“…It is important to review this concept since emotional regulation is one of the Executive Functions that is affected in people with ADHD, causing an impact on the person and their social functioning throughout life. …”
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1351
Predictive biomarkers for cardiometabolic risk in postmenopausal women: insights into visfatin, adropin, and adiponectin
Published 2025-02-01“…The selection of visfatin, adropin, and adiponectin as biomarkers is based on their significant roles in metabolic regulation and inflammation, which are critical factors in cardiometabolic risk. …”
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1352
Metformin Ameliorates Ulcerative Colitis Through Inhibiting NLRP3 Inflammasome Activation
Published 2025-02-01“…In addition, the level of IL-1β in serum was remarkedly down-regulated by Met. In vitro, Met could inhibit NLRP3 inflammasome activation and subsequently dampen the maturation of pro-caspase-1 and pro-IL-1β. …”
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1353
Super-twisting sliding mode control of grid-side inverters for wind power generation systems with parameter perturbation
Published 2025-04-01“…Further, the predictable control gain and time-varying control gain in three STSMC controllers are designed to minimize control system energy expenditure caused by over-regulation and prevent excessive computation of uncertainty boundaries following system disturbances. …”
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1354
Just-In-Time Adaptive Interventions to Promote Behavioral Health: Protocol for a Systematic Review
Published 2025-02-01“…In addition, conditional upon a sufficiently homogeneous literature, we will conduct meta-analyses to investigate the effectiveness of JITAIs for promoting distal outcomes (here, aspects of behavioral health) and proximal outcomes (eg, emotion regulation). MethodsThis systematic review is being conducted in accordance with the PRISMA-P (Preferred Reporting Items for Systematic Reviews and Meta-Analyses Protocols). …”
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1355
Sex differences in the neuroinflammatory signaling pathway: effect of miRNAs on fatty acid synthesis in microglia
Published 2025-02-01“…Notably, testosterone has been reported to regulate cognitive functions in the brain, with low serum testosterone levels correlating with increased AD risk. …”
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1356
Network pharmacology and experimental verification to investigate the mechanism of isoliquiritigenin for the treatment of Alzheimer’s disease
Published 2025-02-01“…GO and KEGG pathway analysis found that ISL was significantly enriched in regulation of mitogen-activated protein kinase (MAPK) signaling pathway. …”
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1357
Single-cell transcriptome atlas of lamprey exploring Natterin- induced white adipose tissue browning
Published 2025-01-01“…These findings elucidate vertebrate cellular evolution and advance our understanding of adipose tissue plasticity and metabolic regulation in lampreys.…”
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1358
Heterochrony in orthodenticle expression is associated with ommatidial size variation between Drosophila species
Published 2025-02-01“…Conclusions Taken together, our results suggest that differential timing of otd expression may contribute to natural variation in ommatidia size between D. mauritiana and D. simulans, which provides new insights into the mechanisms underlying the regulation and evolution of compound eye size in insects.…”
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1360
Targeted inhibition of the PTEN/PI3K/AKT pathway by YSV induces cell cycle arrest and apoptosis in oral squamous cell carcinoma
Published 2025-02-01“…RNA-seq and molecular docking revealed that YSV regulated the PTEN/PI3K/AKT signaling pathway. Western blotting confirmed the modulation of this pathway both in vitro and in vivo. …”
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