Salvia deserti Decne., an endemic and rare subshrub from Arabian desert: antidiabetic and antihyperlipidemic effects of leaf hydroethanolic extracts by Arbi Guetat, Slimen Selmi, Abdelrhman T. Abdelwahab, Marwa A. Abdelfattah, Abd Ealrhman M. Elhaj, Roaa T. Mogharbel, M. J. A. Abualreish, Abdullah F. Alanazi, Karim Hosni, Naceur Mejri, Abdennacer Boulila

“…Although their effectiveness, the antidiabetic drugs have many side effects such as cardiovascular diseases, kidney failure, and hepatic complications. Many plant species of the genus Salvia L. such as “Arabian desert sage” (Salvia deserti) should began to be the focus of phytochemical and bioactivity studies.MethodsThe study aims to investigate, first-ever, the antidiabetic and antihyperlipidemic effects of the leaf hydroethanolic extract of S. deserti, an endemic and rare subshrub from Arabian desert. …”
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O-GlcNAcylation attenuates ischemia-reperfusion-induced pulmonary epithelial cell ferroptosis via the Nrf2/G6PDH pathway by Liuqing Yang, Hexiao Tang, Jin Wang, Dawei Xu, Rui Xuan, Songping Xie, Pengfei Xu, Xinyi Li

“…Thus, we generated Ogt1-conditional knockout mice and found that Ogt1 deficiency aggravated ferroptosis, as evidenced by lipid reactive oxygen species (lipid ROS), malondialdehyde (MDA), Fe2+, as well as alterations in critical protein expression glutathione peroxidase 4 (GPX4) and solute carrier family 7 member 11 (SLC7A11). …”
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Integrating Bulk and Single-Cell Transcriptomic Data to Identify Ferroptosis-Associated Inflammatory Gene in Alzheimer’s Disease by Zhou H, Peng Y, Huo X, Li B, Liu H, Wang J, Zhang G

“…FuRong Laboratory, Changsha, Hunan, 410078, People’s Republic of China, Email [email protected] Jian Wang, The Institute of Reproduction and Stem Cell Engineering, School of Basic Medical Sciences, Central South University, Changsha, 410006, People’s Republic of China, Email [email protected]: Ferroptosis is a form of programmed cell death triggered by iron-dependent lipid peroxidation, characterized by iron accumulation and elevated reactive oxygen species (ROS), leading to cell membrane damage. It is associated with a variety of diseases. …”
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Ethnobotanical survey of medicinal plants used in management of breast cancers in Qatar by Rasha.S.Abo El Alaa, Hend Al-Jaber, Fatima Al Zahraa Chokor, Abdullah A. Shaito, Layla Al-Mansoori

“…The present study documented the ethnobotanical knowledge of 13 herbalists in Qatar regarding breast cancer treatment, revealing the use of various plant species from ten different families. Saussurea costus (Falc.) …”
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Functional activity of blood eosinophils in patients with <i>Opisthorchis felineus</i> invasion by V. V. Tsukanov, N. E. Veselova, A. A. Savchenko, O. A. Kolenchukova, I. I. Gvozdev, A. V. Vasyutin, J. L. Tonkikh, E. V. Kasparov, A. G. Borisov, E. G. Gorchilova, M. Yu. Olkhovskaia, N. O. Prokopieva

“…The study of the functional activity of blood eosinophils was carried out in 42 patients with opisthorchiasis and 34 healthy individuals from the control group by chemiluminescent analysis with the measurement of the intensity of production of reactive oxygen species in spontaneous and zymosan-induced reactions in lucigenin- and luminol-dependent processes.Results. …”
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Dissolved Mn(III) is a key redox intermediate in sediments of a seasonally euxinic coastal basin by R. Klomp, R. Klomp, O. M. Żygadłowska, M. S. M. Jetten, V. E. Oldham, N. A. G. M. van Helmond, N. A. G. M. van Helmond, C. P. Slomp, C. P. Slomp, W. K. Lenstra, W. K. Lenstra

“…Dissolved Mn(III)-L is a relatively stable and mobile Mn species, compared to Mn(II), and is therefore more easily transported laterally throughout the coastal zone and possibly also to open marine waters.…”
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Effect of rhGH treatment on lipidome and brown fat activity in prepuberal small for gestational age children: a pilot study by Lorena González, Carolina Gonzalez-Riano, Pablo Fernández-García, Rubén Cereijo, Aina Valls, Andrea Soria-Gondek, Nativitat Real, Belén Requena, Joan Bel-Comos, Patricia Corrales, David Jiménez-Pavón, Coral Barbas, Francesc Villarroya, David Sánchez-Infantes, Marta Murillo

“…Further research is required to clarify the direct effects of rhGH on specific lipid species and batokines, potentially addressing metabolic disturbances linked to obesity and aging.…”
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Tritordeum, barley landraces and ear photosynthesis are key players in cereal resilience under future extreme drought conditions by Ander Yoldi-Achalandabaso, Aitor Agirresarobe, Artūrs Katamadze, Giulia Burini, Omar Vergara-Díaz, Mariana Mota, Cristina Oliveira, Usue Pérez-López, Rubén Vicente

“…., landraces) or ii) developing novel species (e.g., crop hybrids). Our study aimed to identify key functional traits and stress-tolerant germplasm to contribute to designing drought-resilient crops under future Mediterranean climatic conditions. …”
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Quantitative evaluation of essential amino acids and omega-3 long-chain polyunsaturated fatty acids from global marine bivalve aquaculture by Karsoon Tan, Peng Xu, Leiheng Huang, Cong Luo, KhaiHang Choong, Zexin Li, Yu Guo, Kit-Leong Cheong

“…Among different bivalve species, clams and scallops are the most efficient producers of EPA + DHA and EAAs, while oysters produce the least. …”
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Emodin protects against severe acute pancreatitis-associated acute lung injury by activating Nrf2/HO-1/GPX4 signal and inhibiting ferroptosis in vivo and in vitro by Gang Shen, Haiyun Wen, Huijuan Li, Xuetao Zhang, Bowen Lan, Xuanchi Dong, Peng Ge, Yalan Luo, Hailong Chen

“…Moreover, these results also showed that EMO, contrary to the effects of ML385, suppressed the ferroptosis response, which manifested as up-regulated glutathione (GSH) and GPX4 levels in vivo and in vitro and down-regulated malondialdehyde (MDA), superoxide dismutase (SOD), Fe2+, and reactive oxygen species (ROS) levels. Conclusions Our results demonstrated that EMO effectively inhibited ferroptosis both in vivo and in vitro, while also modulating the Nrf2/HO-1/GPX4 signaling pathway to provide protection against SAP-ALI.…”
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Integrated analysis of biochemical, transcriptomic, and metabolomic response mechanisms in Ussuri catfish (Pseudobagrus ussuriensis) under acute heat stress by Qing Liu, Yang Cao, Ruyi Hu, Libo Gu, Lirong Yang, Yu Liu, Weiwei Wang, Liang Xiao, Bugao Li

“…The Ussuri catfish (Pseudobagrus ussuriensis) is an important native economic species in China. However, research on heat stress in P. ussuriensis, particularly concerning gene expression and metabolites, remains limited. …”
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Flowering characteristics and breeding system of Deutzia parviflora by WANG Qi, LI Jinyu, WANG Xinyi, WANG Yixuan, GUO Wei, YUAN Tao

“…[Objective] The study aims to examine the flowering and breeding characteristics of the native plant Deutzia parviflora, promote the resistance breeding and resource utilization of Deutzia as well as enrich the species of flowering shrubs in the northern region. …”
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Prediction of Soil Organic Carbon Content in <italic>Spartina alterniflora</italic> by Using UAV Multispectral and LiDAR Data by Jiannan He, Yongbin Zhang, Mingyue Liu, Lin Chen, Weidong Man, Hua Fang, Xiang Li, Xuan Yin, Jianping Liang, Wenke Bai, Fuping Li

“…<italic>Spartina alterniflora</italic> (<italic>S. alterniflora</italic>), an invasive species characterized by high primary productivity and rapid carbon sequestration capabilities, exerts a substantial impact on SOC concentrations. …”
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ROS-induced cytosolic release of mitochondrial PGAM5 promotes colorectal cancer progression by interacting with MST3 by Shiyang Wang, Xi Wu, Wenxin Bi, Jiuzhi Xu, Liyuan Hou, Guilin Li, Yuwei Pan, Hanfu Zhang, Mengzhen Li, Sujuan Du, Mingxin Zhang, Di Liu, Shuiling Jin, Xiaojing Shi, Yuhua Tian, Jianwei Shuai, Maksim V. Plikus, Moshi Song, Zhaocai Zhou, Lu Yu, Cong Lv, Zhengquan Yu

“…Abstract Aberrant release of mitochondrial reactive oxygen species (mtROS) in response to cellular stress is well known for promoting cancer progression. …”
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Laboratory Rotational Spectroscopy Leads to the First Interstellar Detection of Singly Deuterated Methyl Mercaptan (CH2DSH) by Hayley A. Bunn, Silvia Spezzano, Laurent H. Coudert, Jean-Claude Guillemin, Yuxin Lin, Christian P. Endres, Brant Billinghurst, Olivier Pirali, Jes Jørgensen, Valerio Lattanzi, Paola Caselli

“…We report an extensive rotational spectroscopic analysis of singly deuterated methyl mercaptan (CH _2 DSH) using both millimeter and far-infrared synchrotron spectra to achieve a global torsional analysis of the three lowest torsional substates ( e _0 , e _1 , and o _1 ) of this nonrigid species. A fit including 3419 millimeter-wave transitions along with 43 infrared torsional subband centers was performed with rms deviations of 0.233 MHz and 0.270 cm ^−1 , respectively, resulting in 68 fit parameters. …”
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The ameliorative effects of melatonin against BDE-47-induced hippocampal neuronal ferroptosis and cognitive dysfunction through Nrf2-Chaperone-mediated autophagy of ACSL4 degradati... by Quan Yuan, Mingwei Wang, Zhaoxiang Zhang, Ruofei Wang, Dechao Wang, Zichun Sang, Pu Zhao, Xiaoli Liu, Xiaoying Zhu, Gaofeng Liang, Hua Fan, Dongmei Wang

“…Acyl-CoA synthetase long-chain family member 4 (ACSL4), a key lipid metabolism enzyme dictating ferroptosis sensitivity, accompanied by higher MDA and lipid reactive oxygen species (ROS), was remarkably increased under BDE-47 stress, while melatonin supplementation could suppress the elevated ACSL4 in vivo and in vitro. …”
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Exploring the multifaceted roles of Sonneratia apetala and Nipa fruticans in coastal habitat restoration and bioactive properties discovery by Sabina Yasmine, Rezwana Zaman Proma, Md. Ripaj Uddin, Mohammad Saydur Rahman, Md. Hamedul Islam, Muhammad Abdullah Al Mansur, AHM Shofiul Islam Molla Jamal, Abu Yousuf, Md. Hasnain Mustak, Sarker Kamruzzaman, M. Mahboob Ali Siddiqi

“…Background: Sonneratia apetala and Nipa fruticans are mangrove species, perennial wild plants with significant therapeutic, ecological, and environmental value. …”
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Blue elixir of youth and wellness: The multicomponent-multitarget paradigm of Curcuma caesia Roxb by Sabrina Burattini, Federico Gianfanti, Francesco Onesimo, Sabrina Donati Zeppa, Barbara Canonico, Mariele Montanari, Giovanna Panza, Daniele Lopez, Giosuè Annibalini, Fabiana Fanelli, Roberta Saltarelli, Michele Mari, Michele Retini, Riham Osman, Aghna Mariam, Matteo Micucci, Giovanni Caprioli, Agnese Santanatoglia, Deborah Agostini, Michela Battistelli

“…This study aims to delve into the antioxidative and protective potential of a rhizome extract from Curcuma caesia Roxb., a less explored species within the turmeric family, focusing on its effects on HaCaT cells subjected to UV radiation. …”
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Construction of “Biomigration – Regional Cooling” Multi-functional Ecological Network in Wuhan Urban Agglomeration by Jiajie LI, Yuanyuan GU, Zhong XING

“…This integrated network sustains the regular functioning of diverse ecological processes by interlinking the supply sources of various ecological functions, thereby amplifying the protective benefits of species habitats across urban and rural landscapes and augmenting the thermal comfort of human settlements. …”
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Structure-activity relationship and in silico docking analysis of dicarboximide fungicides on 17β-hydroxysteroid dehydrogenase 1 of human, rat, and pig by Huiqian Chen, Sailing Chen, Yunbing Tang, Yingfen Ying, Shaowei Wang, Yang Zhu, Yiyan Wang, Ren-shan Ge, Ping Duan

“…In conclusion, dicarboximide fungicides inhibit 17β-HSD1 depending on lipophilicity, species, and cysteine residue interactions.…”
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