Natural compounds from medicinal plants against COVID-19 by Anton Kolodnitsky, Nikita Ionov, Irina Gravel, Vladimir Poroikov

“…Nevertheless, all of them have certain limitations: uncertainty in duration, limited efficacy of vaccines, and lack of effective drugs for COVID-19 treatment. …”
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Effects of health education using mobile technologies on caregivers’ knowledge of routine growth monitoring for children aged 9 to 24 months in Kenya by Justus O. S. Osero, Edna N. Osano

“…Unfortunately, many caregivers cease active RGM activities once they exhaust the government-recommended vaccines. The study aimed to find out the effects of health education using mobile technologies on caregivers’ knowledge of RGM. …”
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Factors influencing incomplete immunization among under five years old children at CHUK hospital, Nyarugenge district, Rwanda by Mercy Nwankwo, Chinenye, Elizabeth, Orua

“…Background: Low-income countries still have challenges with vaccine-preventable diseases, despite improvement in immunization coverage in Rwanda, cases of drop out and incomplete immunization persists. …”
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Development and characterization of a reverse genetics system for the lineage II Chicava strain of Machupo virus in a guinea pig model. by Emily Mantlo, Junki Maruyama, John T Manning, Rachel A Reyna, Cheng Huang, Slobodan Paessler

“…<h4>Background</h4>Machupo virus (MACV) is a New World mammarenavirus (hereafter referred to as "arenavirus") and the etiologic agent of Bolivian hemorrhagic fever (BHF). No vaccine or antiviral therapy exists for BHF, which causes up to 35% mortality in humans. …”
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Exploring the role and mechanisms of MAGEA4 in tumorigenesis, regulation, and immunotherapy by Weijian Zhu, Qiang Yi, Zheng Chen, Jiaqi Wang, Kui Zhong, Xinting Ouyang, Kuan Yang, Bowei Jiang, Jianing Zhong, Jinghua Zhong

“…MAGEA4-based TCR-T cell therapy and cancer vaccines show clinical potential. This article comprehensively reviews the structure and function of MAGEA4, as well as recent research progress in solid tumors, providing a theoretical foundation for the clinical translation of MAGEA4 and its application in immunotherapy.…”
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Multi-target and natural product-based multi-drug approach for anti-VEGF resistance in glioblastoma by Sasikumar Jalajakumari Soumya, Kesavan Rathi Arya, Chandran Sheela Abhinand, Padmanabhan Sunitha, Ajitha Prabhakaran Athira, Achuthsankar Sukumaran Nair, Oommen V. Oommen, Perumana R. Sudhakaran

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Inhibition of STING-mediated type I IFN signaling by African swine fever virus DP71L by Lakmal Ranathunga, Sachini Abesinghe, Ji-Won Cha, Niranjan Dodantenna, Kiramage Chathuranga, Asela Weerawardhana, D. K. Haluwana, Nuwan Gamage, Jong-Soo Lee

“…Taken together, these results highlight the important role of DP71L with respect to inhibition of interferon responses and provide guidance for a better understanding of ASFV pathogenesis and the development of live attenuated ASFV vaccines.…”
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Relationship between RSV-hospitalized children and meteorological factors: a time series analysis from 2017 to 2023 by Shuying Wang, Yifan Wang, Yingxue Zou, Cheng-liang Yin

“…Furthermore, continued research into vaccines and therapeutic drugs remains indispensable for augmenting public health outcomes.…”
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Proline isomerization modulates the bacterial IsdB/hemoglobin interaction: an atomic force spectroscopy study by Francesca Pancrazi, Omar De Bei, Francesco Lavecchia di Tocco, Marialaura Marchetti, Barbara Campanini, Salvatore Cannistraro, Stefano Bettati, Anna Rita Bizzarri

“…Abstract Iron surface determinant B (IsdB), a Staphylococcus aureus (SA) surface protein involved in both heme iron acquisition from host hemoglobin (Hb) and bacterial adhesion, is a proven virulence factor that can be targeted for the design of antibacterial molecules or vaccines. Recent single-molecule experiments on IsdB interaction with cell adhesion factors revealed an increase of the complex lifetime upon applying a stronger force (catch bond); this was suggested to favor host invasion under shear stress. …”
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Sealless Production Ultracentrifuge and Its Magnetically Self-Bearing Openable Motors for Purification in Viral Nanotechnology by Emanuel J. Hubmann, Daniel Steinert, Thomas Nussbaumer, Johann W. Kolar

“…Viral nanotechnology enables new possibilities for gene therapies and vaccines. However, the manufacturing of viral vectors lacks a satisfactory production capable method for purification of full capsids. …”
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Simple and Fail-safe Method to Transform Miniprep Escherichia coli Strain K12 Plasmid DNA Into Viable Agrobacterium tumefaciens EHA105 Cells for Plant Genetic Transformation by Beenzu Siamalube, Emmanuel Ehinmitan, Maina Ngotho, Justus Onguso, Steven Runo

“…Plants are genetically engineered to develop disease-free varieties, knock out unsettling traits for crop improvement, or incorporate an antigenic protein to make the plant a green factory for edible vaccines. The method’s robustness was validated through successful transformations, demonstrating its effectiveness as a standard approach for researchers working in plant biotechnology. …”
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Global progress, challenges and strategies in eliminating public threat of viral hepatitis by Sihui Zhang, Fuqiang Cui

“…While improving the coverage of vaccine use, drugs for treating hepatitis B are not only becoming more effective, but also decreasing in price. …”
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Eastern equine encephalitis virus: Pathogenesis, immune response, and clinical manifestations by Bhumika Parashar, Rishabha Malviya, Sathvik Belagodu Sridhar, Tarun Wadhwa, Sirajunisa Talath, Javedh Shareef

“…By collating current knowledge, this review underscores the urgent need for the development of targeted vaccines and therapeutic interventions to mitigate the growing threat of EEEV, particularly in the context of climate change-driven geographical expansion.…”
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Impact of Social Assistance Grants for Empowerment on Standards of Living of Elderly Persons in Kabale Municipality Kabale District. by Naturinda, Suzan

“…The study results on the effect of social assistance grants for empowerment on the health of the elderly in Kabale Municipality, the highest number of respondents mentioned that social assistance grants for empowerment can help to alleviate financial stress which leads to better physical health outcomes for elderly persons while the least number of respondents mentioned that social assistance grants for empowerment help elderly individuals stay healthy since they can be able to purchase vaccines and have good health. The study findings on the effect of social assistance grants for empowerment on the consumption of elderly in Kabale Municipality, the highest number of respondents mentioned that social assistance grants for empowerment can alleviate financial stress and uncertainty for elderly individuals, allowing them to budget more effectively and plan for future consumption needs while the least number of respondents mentioned that social assistance grants for empowerment allows elderly persons to allocate more of their funds towards consumption for better health. …”
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Incompatible Aedes aegypti male releases as an intervention to reduce mosquito population-A field trial in Puerto Rico. by Liliana Sánchez-González, Jacob E Crawford, Laura E Adams, Grayson Brown, Kyle R Ryff, Mark Delorey, Jose Ruiz-Valcarcel, Nicole Nazario, Nexilianne Borrero, Julieanne Miranda, Sara N Mitchell, Paul I Howell, Johanna R Ohm, Charlie Behling, Brian Wasson, Craig Eldershaw, Bradley J White, Vanessa Rivera-Amill, Roberto Barrera, Gabriela Paz-Bailey

“…Without widely available vaccines, mosquito control is the primary tool for fighting the spread of these viruses. …”
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Effect of Double Masking with Silk or Cotton Over-masks on the Source Control Capabilities of a Surgical Mask by Adam F. Parlin, Mikhail Yermakov, Samuel M. Stratton, Susan R. Reutman, Theresa M. Culley, Patrick A. Guerra, Sergey A. Grinshpun

“…Abstract In spite of the remarkable progress made in the development of safe and effective vaccines against COVID-19, deployment of respiratory protective devices remains vital for mitigating the transmission of SARS-CoV-2 during the ongoing pandemic. …”
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Prevalence and correlates of facemask usage during the second wave of COVID-19 pandemic in Uganda. by Nelson Onira Alema, Christopher Okot, Emmanuel Olal, Eric Nzirakaindi Ikoona, Freddy Wathum Drinkwater Oyat, Steven Baguma, Denish Omoya Ochula, Patrick Odong Olwedo, Johnson Nyeko Oloya, Francis Pebalo Pebolo, Pamela Okot Atim, Godfrey Smart Okot, Ritah Nantale, Judith Aloyo, David Lagoro Kitara

“…We conducted a cross-sectional study on 587 adults across nine districts in northern Uganda, across 24 high-volume health facilities offering free COVID-9 vaccines. Respondents were selected from the health facilities using a single-stage systematic sampling method. …”
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Targeted therapy and immunotherapy for gastric cancer: rational strategies, novel advancements, challenges, and future perspectives by Dong Luo, Yunmei Liu, Zhengmao Lu, Lei Huang

“…Innovative immunotherapy modalities, including adoptive immune cell therapy, tumor vaccines, and non-specific immunomodulators therapy, and oncolytic viruses have shown promise in early-stage clinical trials for GC. …”
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Estimating the Health-Related Quality of Life Benefit of Prophylactic Treatment for COVID-19 in Immunocompromised People: A Multimethod Valuation Study by Katy Gallop, Rebekah Hall, Michael Watt, Daniel Squirrell, Neil Branscombe, Sofie Arnetop, Andrew Lloyd

“…**Background:** Pre-exposure prophylaxis (PrEP) for COVID-19 provides additional protection, beyond vaccines alone, for individuals who are immunocompromised (IC). …”
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Atomic Force Microscopy (AFM) nanomechanical characterization of micro- and nanoplastics to support environmental investigations in groundwater by Massimiliano Galluzzi, Michele Lancia, Chunmiao Zheng, Viviana Re, Valter Castelvetro, Shifeng Guo, Stefano Viaroli

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