Minimizing Honey Bee Exposure to Pesticides by James D. Ellis, Jeanette Klopchin, Eileen Buss, Frederick M. Fishel, William H. Kern, Catharine Mannion, Eugene McAvoy, Lance S. Osborne, Michael Rogers, Malcolm Sanford, Hugh Smith, Phillip Stansly, Lukasz Stelinski, Susan Webb

“…Kern, C. Mannion, E. McAvoy, L. S. Osborne, M. Rogers, M. Sanford, H. Smith, P. …”
Get full text

Assessing the quality of life among African medical and health science students using the WHOQOL-BREF tool by Fatima Alzahra Galgam, Adil Abdalla, Mahmoud Shahin, Magda Yousif, Nahla Abdulrahman, Fatmah Alamoudi, Mehrunnisha Ahmad, Amira Yahia, Mohammad Sidiq, Aksh Chahal, Fuzail Ahmad, Mohammad Abu Shaphe, Gopal Nambi, Moattar Raza Rizvi, Faizan Kashoo

“…Background The quality of life (QoL) among health professional students is available in the literature, yet there is a paucity of information concerning QoL among African students. The study aimed to measure the QoL with the World Health Organization Quality of Life-BREF (WHOQOL-BREF) tool among African medical and health science students. …”
Get full text

2018 Vegetable Production Handbook Chapter 15: Root Crop Production by Peter J. Dittmar, Eugene J. McAvoy, Monica Ozores-Hampton, Richard Raid, Hugh A. Smith, Bonnie Wells, Julien Beuzelin, Johan Desaeger, Joseph W. Noling, Lincoln Zotarelli, Shouan Zhang, Christian F. Miller, Qingren Wang

“…Written by Peter J. Dittmar, Eugene J. McAvoy, Monica Ozores-Hampton, Richard Raid, Hugh A. …”
Get full text

Neuroprotective role of epigallocatechin-3-gallate, albeginin and melanoxetin in alzheimer's disease by Arif Malik, Mehreen Hassan, Sulayman Waquar, Muhammad Wasim, Anam Naz, Faryal M. Awan, Muhammad T. Khan, Ali I. Khawaja, Sumera Zaib, Jamshed Iqbal, Ayesha Zahid, Marvi Marvi, Javeid Iqbal, Heng Wang, Dong-Qing Wei

“…Melanoxetin, a phenolic molecule, chelates toxic metals, lowers ROS, and protects neurons at 15–40 mg/kg/day in animal models and 50–150 mg/day in humans. These chemicals show promise for Alzheimer's treatment. …”
Get full text

Systemic delivery of AAV5, AAV8, and AAV9 packaging a C5-12-microdystrophin-FLAG expression cassette in non-human primates by Mengping Liu, Erica Cook, Yanshan Dai, Erich Ehlert, Francois du Plessis, Jacek Lubelski, Bogdan G. Sleczka, Petia Shipkova, Zhuyin Li, Joshua Gamse, David Gordon, Leonard P. Adam, Paul C. Levesque, Glen B. Banks

Get full text

Baccaurea ramiflora fruit peel powder supplementation prevented inflammatory cell infiltration, oxidative stress, and fibrosis in carbon tetrachloride (CCl4) administered ovariecto... by Tahsin Zahan, Mirza Alimullah, Ishrat Jahan, Md. Borhan Uddin, Khondker Ayesha Akter, Md. Junaeid Rahman, Shahnaz Siddiqua, Kamrun Nahar Ela, Sakil Amin, Khondoker Shahin Ahmed, Hemayet Hossain, Ferdous Khan, Md Ashraful Alam, Nusrat Subhan

“…The catalase and superoxide dismutase activities were also restored in the plasma of CCl4-administered rats. …”
Get full text

Urinary bacteriophage cooperation with bacterial pathogens during human urinary tract infections supports lysogenic phage therapy by Mahmood Almosuli, Anna Kirtava, Archil Chkhotua, Lia Tsveniashvili, Nina Chanishvili, Sumaiya Safia Irfan, Emily Ng, Hope McIntyre, Adam J. Hockenberry, Robyn P. Araujo, Weidong Zhou, Ngoc Vuong, Barbara Birkaya, Lance Liotta, Alessandra Luchini

Get full text

Peroral endoscopic myotomy with fundoplication (POEM-F) for achalasia: Systematic review and meta-analysis by Harishankar Gopakumar, Eugene Annor, Ishaan Vohra, Iman Andalib, Amy Tyberg, Avik Sarkar, Haroon Shahid, Mine Carames, Juan Carlos Carames, Giovanna Porfilio Gularte, Abed Al-Lehibi, Resheed Alkhiari, Amol Bapaye, Carlos Robles-Medranda, Michel Kahaleh

“… Background and study aims: Gastroesophageal reflux (GER) and its long-term sequelae remain a concern following peroral endoscopic myotomy (POEM). …”
Get full text

Amyloids in bladder cancer hijack cancer-related proteins and are positive correlated to tumor stage by Diego Alem, César X. García-Laviña, Francisco Garagorry, Dardo Centurión, Joaquina Farias, Hany Pazos-Espinosa, María Noel Cuitiño-Mendiberry, Carolina Villadóniga, Susana Castro-Sowinski, Martín Fló, Federico Carrión, Brenda Iglesias, Kevin Madauss, Lucía Canclini

Get full text

Collection of SARS-CoV-2 Virus from the Air of a Clinic within a University Student Health Care Center and Analyses of the Viral Genomic Sequence by John A. Lednicky, Sripriya N. Shankar, Maha A. Elbadry, Julia C. Gibson, Md. Mahbubul Alam, Caroline J. Stephenson, Arantzazu Eiguren-Fernandez, J. Glenn Morris, Carla N. Mavian, Marco Salemi, James R. Clugston, Chang-Yu Wu

Get full text

Rimegepant for the treatment of migraine by Amnon A. Berger, Ariel Winnick, Austin H. Carroll, Alexandra Welschmeyer, Nathan Li, Marc Colon, Antonella Paladini, Giovanni F. Ramírez, Jamal Hasoon, Elyse M. Cornett, Jaehong Song, Giustino Varrassi, Adam M. Kaye, Alan D. Kaye, Latha Ganti

“…It is also generally safer for use than existing options, does not appear to increase the chance of developing chronic migraines, and carries a very tolerable side effects profile. …”
Get full text

Discrete vulnerability to pharmacological CDK2 inhibition is governed by heterogeneity of the cancer cell cycle by Vishnu Kumarasamy, Jianxin Wang, Michelle Roti, Yin Wan, Adam P. Dommer, Hanna Rosenheck, Sivasankar Putta, Alec Trub, John Bisi, Jay Strum, Patrick Roberts, Seth M. Rubin, Costakis Frangou, Karen McLean, Agnieszka K. Witkiewicz, Erik S. Knudsen

Get full text

Non-canonical lysosomal lipolysis drives mobilization of adipose tissue energy stores with fasting by GV Naveen Kumar, Rui-Sheng Wang, Ankit X. Sharma, Natalie L. David, Tânia Amorim, Daniel S. Sinden, Nandini K. Doshi, Martin Wabitsch, Sebastien Gingras, Asim Ejaz, J. Peter Rubin, Bradley A. Maron, Pouneh K. Fazeli, Matthew L. Steinhauser

Get full text

Unique North American isolates of severe metastatic hypervirulent Klebsiella pneumoniae strain infections with hepatic abscesses seen in young patients within Texas. by Junaid M Alam, Eric N Riha, Haris Ahmed, Hong M Thai, Kevin Garnepudi, Ramesh B Kesavan, Gnananandh Jayaraman, Anna Sangster, Dylan Curry, Heidi A Butz, Lori Smith, Maureen Vowles, Kelly F Oakeson, Erin L Young, Siva T Sarva

Get full text

Dendritic excitations govern back-propagation via a spike-rate accelerometer by Pojeong Park, J. David Wong-Campos, Daniel G. Itkis, Byung Hun Lee, Yitong Qi, Hunter C. Davis, Benjamin Antin, Amol Pasarkar, Jonathan B. Grimm, Sarah E. Plutkis, Katie L. Holland, Liam Paninski, Luke D. Lavis, Adam E. Cohen

Get full text

Repression of CADM1 transcription by HPV type 18 is mediated by three-dimensional rearrangement of promoter-enhancer interactions. by Karen Campos-León, Jack Ferguson, Thomas Günther, C David Wood, Steven W Wingett, Selin Pekel, Christy S Varghese, Leanne S Jones, Joanne D Stockton, Csilla Várnai, Michelle J West, Andrew Beggs, Adam Grundhoff, Boris Noyvert, Sally Roberts, Joanna L Parish

“…Since CTCF is an important regulator of host cell transcription via coordination of epigenetic boundaries and long-range chromosomal interactions, we hypothesised that HPV18 may also manipulate CTCF to contribute to host transcription reprogramming. …”
Get full text

An ontology-based rare disease common data model harmonising international registries, FHIR, and Phenopackets by Adam S. L. Graefe, Miriam R. Hübner, Filip Rehburg, Steffen Sander, Sophie A. I. Klopfenstein, Samer Alkarkoukly, Ana Grönke, Annic Weyersberg, Daniel Danis, Jana Zschüntzsch, Elisabeth F. Nyoungui, Susanna Wiegand, Peter Kühnen, Peter N. Robinson, Oya Beyan, Sylvia Thun

“…Abstract Although rare diseases (RDs) affect over 260 million individuals worldwide, low data quality and scarcity challenge effective care and research. This work aims to harmonise the Common Data Set by European Rare Disease Registry Infrastructure, Health Level 7 Fast Healthcare Interoperability Base Resources, and the Global Alliance for Genomics and Health Phenopacket Schema into a novel rare disease common data model (RD-CDM), laying the foundation for developing international RD-CDMs aligned with these data standards. …”
Get full text

Diagnostic accuracy of calculated serum osmolarity to predict dehydration in older people: adding value to pathology laboratory reports by Lee Shepstone, John F Potter, Lee Hooper, Asmaa Abdelhamid, Amy Jennings, Paul R Hunter, W Garry John, Neil P Walsh, Adam Ali, Diane K Bunn, Susan Kerry, Gregor Lindner, Carmen A Pfortmueller, Fredrik Sjöstrand, Susan J Fairweather-Tait

“…Objectives To assess which osmolarity equation best predicts directly measured serum/plasma osmolality and whether its use could add value to routine blood test results through screening for dehydration in older people.Design Diagnostic accuracy study.Participants Older people (≥65 years) in 5 cohorts: Dietary Strategies for Healthy Ageing in Europe (NU-AGE, living in the community), Dehydration Recognition In our Elders (DRIE, living in residential care), Fortes (admitted to acute medical care), Sjöstrand (emergency room) or Pfortmueller cohorts (hospitalised with liver cirrhosis).Reference standard for hydration status Directly measured serum/plasma osmolality: current dehydration (serum osmolality >300 mOsm/kg), impending/current dehydration (≥295 mOsm/kg).Index tests 39 osmolarity equations calculated using serum indices from the same blood draw as directly measured osmolality.Results Across 5 cohorts 595 older people were included, of whom 19% were dehydrated (directly measured osmolality >300 mOsm/kg). …”
Get full text

Cellular rejuvenation protects neurons from inflammation-mediated cell death by Sienna S. Drake, Abdulshakour Mohammadnia, Aliyah Zaman, Christine Gianfelice, Kali Heale, Adam M.R. Groh, Elizabeth M.-L. Hua, Matthew A. Hintermayer, Yuancheng Ryan Lu, David Gosselin, Stephanie Zandee, Alexandre Prat, Jo Anne Stratton, David A. Sinclair, Alyson E. Fournier

Get full text