Targeting the G-quadruplex as a novel strategy for developing antibiotics against hypervirulent drug-resistant Staphylococcus aureus by Maria Sultan, Maria Razzaq, Joohyun Lee, Shreyasi Das, Shrute Kannappan, Vinod Kumar Subramani, Wanki Yoo, Truc Kim, Hye-Ra Lee, Akhilesh K. Chaurasia, Kyeong Kyu Kim

“…Conclusions In summary, the current study identified NMM as a broad-spectrum potent antibacterial agent and elucidated its plausible mechanism of action primarily by targeting G4-motif in the mraZ promoter of the dcw gene cluster.…”
Get full text

Analisis Dukungan Petugas Kesehatan Dalam Optimalisasi Competence Baby Care Pada Ibu muda Melalui Pendekatan Maternal Sensitivity Models Berbasis Keluarga (Analysis of Health Of... by diyan indriyani

“…Pendekatan penelitian berupa partisipatif (kualitatif) dan Participatory Action Reseacrh (PRA). Tehnik pengumpulan data melalui Focus Group Discussion (FGD) dan indept interview pada petugas kesehatan di Puskesmas Sumbersari dan Sukorambi Jember sejumlah 9 partisipan, sedangkan jumlah responden yang menjadi subyek penelitian adalah 50 keluarga. …”
Get full text

A Program for Master of Science in Environment and Natural Resources (MENR) by Kabale University

“…According to UN Sustainable Development Goals (SDG), the Goals and targets will stimulate action over the next 15 years in areas of critical importance for humanity and the planet. …”
Get full text

The Role of Psychology Towards Sustainable Development Goal 3: Good Health and Wellbeing in South Africa by Ntombophelo Sithole-Tetani

“…The 2030 Agenda for Sustainable Development, as it is known, is a call to action to end poverty, protect the planet, and ensure prosperity for all. …”
Get full text

Advantages and disadvantages of coronary drug-eluting stent: a 23-year journey of randomized clinical trials by Alfredo E. Rodriguez, Juan Mieres, Juan M. Rokos

“…The finding of a high incidence of non-cardiac death observed in DES trials compared to coronary artery bypass grafting and optimal medical treatment is disturbing, and the reasons are unknown. Prompt action should be taken by the sponsors of the trials, scientific societies, and/or regulatory agencies to confirm or discard this intriguing observation. …”
Get full text

Current Trends in Treatment for Acid-Dependent Diseases: Clinical Efficacy and Safety of Rabeprazole by O. D. Lopina, B. K. Nurgalieva, T. L. Lapina

“…The rabeprazole properties of high acid suppression potential, persistent antisecretory effect from first day of therapy, non-enzymatic metabolism and pleiotropic action determine its high efficacy in treatment for a wide range of acid-dependent diseases at a minimal risk of drug interaction.…”
Get full text

The importance of the general system theory for the modern world by Šijan Aleksandar, Karabašević Darjan, Rajčević Dušan

“…The paper explains how diffusion and fragmentation across scientific disciplines created needs within the science that further motivated action to create metatheory that would resolve this fragmentation and atomization through a unique - umbrella approach. …”
Get full text

Sinemada Motion Capture Uygulamalarında Yazılım Şirketlerin Estetik ve Teknolojik Çözümleri by Ersin Kozan

“…Film yapımında motion capture teknolojisinin başta animasyon türünde sinema filmlerinde kullanılması dışında live action türünde sinema filmlerinde de artan yoğun kullanımına şahit olunmaktadır. …”
Get full text

Gendering the Decision-Making Positions in Higher Education: A Cross-Sectional Gender Audit in Three Selected Universities in Malawi by Juliet Chiwaya Kamwendo

“… Malawi is one of the countries that has doubled its efforts to narrow the gender gap since the 1995 Beijing Platform for Action. The country ratified both international and regional gender protocols as well as enacting the national gender policy to safeguard gender equality at all levels to empower women. …”
Get full text

Effects of an Educational Comic Book on Knowledge Related to the Safe Use of Fluoride Toothpaste in Children by Henrique Cesar de Souza Perez, Luciane Zanin de Souza, Flávia Martão Flório

“…Material and Methods: This is a quantitative action research aimed at evaluating the effect of a comic book on the necessary knowledge for indirectly supervised tooth brushing practices in early childhood education. …”
Get full text

NIR-activated catechol-functionalized nanodiamond nanofibers for accelerating on-demand MRSA and E. coli biofilm eradication by Hyeonseo Park, Tejal V. Patil, Jieun Lee, Hojin Kim, Seong-Jun Cho, Ki-Taek Lim

“…Our research proposes a platform that not only effectively addresses antibiotic-resistant infections but also contributes to advancements in wound healing therapies by enabling controlled antibacterial action with minimal toxicity.…”
Get full text

Deep learning based gasket fault detection: a CNN approach by S. Arumai Shiney, R. Seetharaman, V. J. Sharmila, S. Prathiba

“…The proposed method automates the detection of misaligned or incorrectly fitting gaskets, ensuring timely repair action. The suggested method uses deep learning approaches to recognize and evaluate radiator images, with a focus on identifying misaligned or incorrectly installed gaskets. …”
Get full text

Functional characteristics of serotoninergic nerves stimulating stomach and intestinal contractions by V. M. Smirnov, D. S. Sveshnikov, T. Ch. Kuznetsova, M. I. Mongush, O. S. Rayevskaya

“…Stimulatory effect for the stomach considerably exceeds brake action of sympathetic nerve. Comparative analysis of serotoninergic nerve functional properties versus sympathetic nerve was carried out. …”
Get full text

Restorative Justice Policy Model in the Future of Criminal Law by Rado Rudini Hasyim, Restu Monika Nia Betaubun, Emiliana B. Rahail

“… Restorative justice as a constructive, creative, self-determined action with assistance and open opportunities for group involvement. …”
Get full text

Natura, architektura i zabawa jako źródła przeżyć estetycznych i odkryć geometrycznych dzieci – badania w działaniu by Barbara Bilewicz-Kuźnia, Małgorzata Centner-Guz

“…The current paper presents the methods of using them for playing, observing nature and architecture, that were validated in action research. The aim of the methodological solutions described here is to sensitize children to discovering beauty and geometrical dependencies in their surroundings, as well as to develop their spatial thinking. …”
Get full text

THE CHORAL OUTLINE IN THE OPERA “ALEXANDRU LĂPUŞNEANU” BY GHEORGHE MUSTEA by Luminiţa GUŢANU

“…They are largely developed in this opera, in addition to the fact that they integrate the general atmosphere of the action, rather than outlining various personalities or feelings. …”
Get full text

Prenatal Acetaminophen Exposure and its Associated Risk for Attention Deficit Hyperactivity Disorder by Noah J. Spillers, Norris C. Talbot, Patrick M. Luther, Gianni H. Ly, Caylin J. Roberts, Shahab Ahmadzadeh, Sahar Shekoohi, Omar Viswanath, Alan D. Kaye

“…The risks and benefits of treatment should be considered so that the patient may continue with the course of action with the most favorable outcome. This review was mainly based on manuscripts pulled from Google Scholar and PubMed. …”
Get full text

Neurosurgical aspects of marble bone disease: treatment modalities and outcome by Mahmoud Mohammed Gamal, Roshdy Elkhayat, Hassan Mohammed Hassan

“…Abstract Background Marble bone disease or osteopetrosis is an extremely rare hereditary condition that causes abnormal bone density and fragility due to impaired osteoclastic action. This causes the body to produce an abnormal amount of bone that are evident in radiographic findings and cause problems with the body systems, particularly the nervous system. …”
Get full text

Modern options of prokinetics in gastroesophageal reflux disease treatment by A. A. Sheptulin, A. A. Kurbatova, S. A. Baranov

“…GERD belongs to acid-related diseases, because detrimental action of hydrochloric acid on esophageal mucosa plays major role in its pathogenesis. …”
Get full text

Bound states of massive complex ghosts in superrenormalizable quantum gravity theories by M. Asorey, G. Krein, M. Pardina, I. Shapiro

“…Abstract One of the remarkable differences between renormalizable quantum gravity with four-derivative action and its superrenormalizable polynomial generalizations is that the latter admit a more sophisticated particle mass spectrum. …”
Get full text