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1021
Phytochemistry and pharmacological advances of Ascophyllum nodosum in the management of human diseases: A comprehensive review
Published 2025-02-01“…Results: We conducted a comprehensive review of the research progress on ANE, focusing on its pharmacological effects on various diseases using animal models, mechanisms of action, and composition, are as not explored in preceding reviews. …”
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1022
Rock fracture mode and acoustic emission characteristics under true triaxial single-sided unloading path
Published 2025-02-01“…While the proportions of tensile cracks in siltstone and fine sandstone are 41.43% and 56.41% respectively. Under the action of axial stress, they are prone to longitudinal splitting and form tensile cracks approximately parallel to the direction of the maximum principal stress. …”
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1023
Microbial proliferation deteriorates the corrosion inhibition capability, lubricity, and stability of cutting fluid
Published 2025-02-01“…The rolling and bridging action of the resulting fungal mycelium caused flocculation of the effective components in the cutting fluid, resulting in reduced lubricity and poor stability. …”
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1024
Research progress and application prospects of flexible wearable sensor in spacesuit
Published 2025-02-01“…It can realize the benefits of heart rate, breathing, sweat, action recognition and date acquisition, etc. The joint resistance characteristics of spacesuit is revealed under pressure were studied by wearing flexible wearable sensors, which provides a theoretical basis for improving the performance of spacesuit. …”
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1025
Biodiversity reporting: Comparing listed entities in the United Kingdom and South Africa
Published 2025-01-01“…Practical implications: The disclosure schematic serves as a valuable tool for evaluating biodiversity reporting in different national contexts and provides a framework for companies developing biodiversity action plans. The findings help stakeholders assess organisations’ progress in achieving biodiversity objectives and integrating biodiversity considerations into business operations. …”
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1026
The mental health impact of COVID-19: the need for community interventions and collaboration for recovery
Published 2024-01-01“…Materials and methods: This qualitative study aims to map out the mental health consequences of the COVID-19 pandemic and suggest recovery strategies based on analyzing COVID-19 mental health and psychosocial impact-related comments on social/news media, participant’s observations, and participant action research. The results and suggested recovery strategies were triangulated with literature survey. …”
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1027
Heterologous expression of SpsTAC2 in Arabidopsis affected branch angle and secondary vascular system development
Published 2025-12-01“…This study can help to characterize the regulatory effect of the TAC gene on the branching angle and explore its effect on the branching angle and vascular system development, and also help to explore the possible molecular regulatory mechanism, which can provide a theoretical basis for further elucidation of the mechanism of action of the IGT gene family.…”
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1028
Practical Aspects of Clinical Manifestations, Pathogenesis and Therapy of Alcoholic Liver Disease and Non-alcoholic Fatty Liver Disease: Expert Opinion
Published 2023-11-01“…In the treatment of NAFLD, diet and lifestyle modification, weight loss, the use of insulin sensitizers, vitamin E, statins (in the presence of hyperlipidemia) and drugs with metabolic activity are effective.Currently, a point of view is being actively expressed about the synergism of the action of alcohol and the metabolic syndrome on the development of fibrosis, cirrhosis, and hepatocellular carcinoma. …”
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1029
How integrated knowledge translation worked to reduce federal policy barriers to the implementation of medication abortion in Canada: a realist evaluation
Published 2025-02-01“…We found key components of the causal explanatory configurations included: researcher motivation to move evidence into action, trusted reputations as credible sources of evidence, strategic partnerships, understanding of health policy processes, and researcher roles as a trusted convenor between key groups and decision makers. …”
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1030
A cognitive model of perceptual anomalies: The role of source monitoring, top-down influence and inhibitory processes for hallucinations in schizophrenia spectrum disorders and hal...
Published 2025-04-01“…Methods: Eighty-nine patients with schizophrenia spectrum disorders (SSD) were divided into two groups based on AHs presence - 46 with AHs and 43 - non-hallucinating, 43 matched healthy controls (HC), and a sample selected from the general population of 40 participants with high HLEs and 43 with low HLEs performed three experimental tasks assessing top-down processes (False Perception Task - FPT), source monitoring (Action Memory Task - AMT), and inhibitory control (Go/No-Go Task). …”
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1031
Long-chain chlorinated paraffins (LCCPs) exposure induces apoptosis in primary chicken embryo hepatocytes through oxidative stress
Published 2025-01-01“…Consequently, this study employed primary chicken embryo hepatocyte as a model to investigate the toxicological effects of LCCPs exposure and its potential mechanisms of action. Our findings indicate that the proliferation capacity of primary chicken embryo hepatocytes exposed to LCCPs at concentrations of 1, 10, and 100 μg/L was significantly diminished, with an observed arrest in the G0/G1 phase and a notable reduction in the proportion of cells in the G2/M phase. …”
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1032
Extracecellulr vesicles (EVs) microRNAs (miRNAs) derived from mesenchymal stem cells (MSCs) in osteoarthritis (OA); detailed role in pathogenesis and possible therapeutics
Published 2025-02-01“…Thus, the biosynthesis, chemical makeup, and mechanism of action of miRNAs-enriched EVs in OA are all thoroughly covered in this review. …”
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1033
Understanding sociodemographic differences in climate behavior, climate policy acceptance, and political participation
Published 2025-01-01“…Methods: Data from four waves (2022–2023) of the Planetary Health Action Survey (PACE) were analyzed (N = 3,830, nonprobabilistic representative German sample). …”
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1034
The clinical journey of belantamab mafodotin in relapsed or refractory multiple myeloma: lessons in drug development
Published 2025-02-01“…It considers how incorporating longer follow-up in DREAMM-3 may have better captured the clinical benefits of belantamab mafodotin, particularly given its multimodal, immune-related mechanism of action with responses deepening over time. A non-inferiority hypothesis may have been more appropriate rather than superiority in the context of a monotherapy versus an active doublet therapy. …”
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1035
An Overview of the Impact of Statin Therapy on Cardiac Incident Risk
Published 2025-02-01“…This review presents a comprehensive overview of the impact of statin therapy on cardiac incident risk, examining its efficacy in primary and secondary prevention, the underlying mechanisms of action, associated adverse effects, and considerations for patient adherence. …”
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1036
Pathogenetic Substantiation of the Therapeutic Impact on Microbiota in Irritable Bowel Syndrome
Published 2019-09-01“…The majority of studies on IBS have demonstrated the predominance of intestinal bacteria with pro-inflammatory potential (Enterobacteriaceae) and the lack of bacteria with a pronounced anti-inflammatory, antimicrobial and enzymatic action (Lactobacillus and Bifidobacterium), as well as increased mucus degradation. …”
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1037
The Role of Non-Governmental Organisations (NGOs) on the Socio¬economic Transformation of Rural Areas in Nyarusiza Sub-County Kisoro District.
Published 2023“…The data collection methods are put into action in Chapter 3. The research used both qualitative and quantitative methods of data collection and analysis. …”
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1038
Assessing the Role of MBIFCT as a Non-Governmental Organisations (NGO) in Socio-Economic Transformation of Rural Areas in Gitenderi Parish Nyarusiza Sub-County Kisoro District.
Published 2023“…In chapter three this is where the methods of data collection were put into action. The research used both qualitative and quantitative methods of data collection and analysis. …”
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1039
Gender Relations and Women Empowerment in Kisoro Municipality.
Published 2023“…There was a critical review of the issues that have been explored and studied both theoretically and empirically in the existing literature on gender relations as an independent variable women empowerment as the dependent variable and the methods of data collection were put into action. The research used 80 respondents as the sample size, and both qualitative and quantitative methods of data collection and analysis were employed. …”
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1040
Impact of Maziba Church of Uganda on Family Stability in Maziba Sub-County Kabale District.
Published 2024“…In chapter three this is where the methods of data collection were put into action. The research used both qualitative and quantitative methods of data collection and analysis. …”
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Thesis