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  1. 1081

    Role of Fcγ receptors in HER2-targeted breast cancer therapy by Hope S Rugo, Antonino Musolino, William J Gradishar, Jeffrey L Nordstrom, Edwin P Rock, Fernanda Arnaldez, Mark D Pegram

    Published 2022-01-01
    “…Several therapeutic monoclonal antibodies (mAbs), including those targeting epidermal growth factor receptor, human epidermal growth factor receptor 2 (HER2), and CD20, mediate fragment crystallizable gamma receptor (FcγR)–dependent activities as part of their mechanism of action. These activities include induction of antibody-dependent cellular cytotoxicity (ADCC) and antibody-dependent cellular phagocytosis (ADCP), which are innate immune mechanisms of cancer cell elimination. …”
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    Article
  2. 1082

    Mitigating effects of Jiawei Chaihu Shugan decoction on necroptosis and inflammation of hippocampal neurons in epileptic mice by Qin Wang, Baijun Qin, Han Yu, Jiawei Zeng, Jingjing Fan, Qiong Wu, Rong Zeng, Haichun Yu, Xian Zhang, Mingfen Li, Yanying Zhou, Limei Diao

    Published 2025-02-01
    “…Abstract Jiawei Chaihu Shugan decoction (JWCHSGD) is a traditional Chinese medicine well-known for its beneficial effects in treating epilepsy (Xianzheng in ancient Chinese), but the molecular mechanism of its action remains unclear. To investigate the molecular mechanism of JWCHSGD’s prevention of epilepsy-mediated neuron from necroptosis and inflammation via the circRNA-Csnk1g3/Csnk1g3-85aa/ CK1γ3/TNF-α signal pathway. …”
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    Article
  3. 1083

    Circular RNA encoded by PPARG in the peripheral blood and a lipopolysaccharide-induced cardiomyocyte inflammation model is identified as a marker of fulminant myocarditis by Shasha Huang, Shumin He, Fei Xiao, Yang Zhou, Su Lyu

    Published 2025-02-01
    “…Biological function classification and enrichment analysis were used to explore the main action pathways involving differentially expressed circRNAs. …”
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    Article
  4. 1084

    Cloud-edge hybrid deep learning framework for scalable IoT resource optimization by Umesh Kumar Lilhore, Sarita Simaiya, Yogesh Kumar Sharma, Anjani Kumar Rai, S. M. Padmaja, Khan Vajid Nabilal, Vimal Kumar, Roobaea Alroobaea, Hamed Alsufyani

    Published 2025-02-01
    “…PPO enhances policies in continuous action spaces to guarantee reliable performance in real-time, dynamic IoT settings. …”
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    Article
  5. 1085

    Effective dietary interventions during pregnancy: a systematic review and meta-analysis of behavior change techniques to promote healthy eating by Hannah O’Connor, Nina Meloncelli, Shelley A. Wilkinson, Anna Mae Scott, Lisa Vincze, Alita Rushton, Samantha Dawson, Jenna Hollis, Bree Whiteoak, Sarah Gauci, Susan de Jersey

    Published 2025-02-01
    “…The BCT category Reward and threat was successful in improving dietary quality and vegetable intake, whilst 'Action planning’ (1.4) from the category Goals and planning significantly improved dietary quality. …”
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    Article
  6. 1086

    Evaluating a novel team learning approach for integrating drugs in sports education in preclinical medical training by Samuel Pelobello, Grayson Potter, Daniel K. Rogstad, Andrew J. Mock, Sean M. Wilson

    Published 2025-02-01
    “…Future iterations will focus on emphasizing drug pharmacology, mechanisms of action, and physiological effects for MS1 students, while providing opportunities for more comprehensive knowledge integration through the case studies for MS2 students. …”
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    Article
  7. 1087

    Influence of diglyme and cumene additives upon emission and combustion behaviour of diverse biodiesel fuelled diesel engine by Swarup Kumar Nayak, Dinesh Babu Munuswamy, Ganesan Subbiah, Mallireddy Naresh, Yuvarajan Devarajan

    Published 2025-03-01
    “…The growing need for sustainable and eco-friendly fuels aligns with global efforts to achieve the United Nations Sustainable Development Goals (SDGs), particularly SDG 7 (Affordable and Clean Energy), SDG 13 (Climate Action), and SDG 12 (Responsible Consumption and Production). …”
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    Article
  8. 1088
  9. 1089

    Efecto de una intervención Act sobre la resistencia aeróbica y evitación experiencial en marchistas / Effect of an ACT Intervention on Aerobic Endurance and Experiential Avoidance... by María Clara Rodríguez-Salazar, Ángela Patricia Valero-Ballesteros

    Published 2015-12-01
    “…The instruments used were the 3000-meter test and the Acceptance and Action Questionnaire (AAQ). The ACT intervention was conducted in four sessions, where they developed the contents defined by the authors of this intervention (Wilson and Luciano, 2002). …”
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    Article
  10. 1090

    Performance of Banana Peelings Extract as A Natural Coagulant in the Treatment of Surface Water Case Study: River Rwizi, Mbarara. by Asingya, Derrick

    Published 2023
    “…However, many researchers have come up with different plant-based coagulants to replace Aluminum sulphate thus, the main objective of this research was to the investigate performance of banana peelings extract as a natural coagulant in the treatment of surface water by comparing the coagulation action of the raw and ripe banana peelings extracts against Aluminium sulphate, a chemical coagulant as the control experiment. …”
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    Thesis
  11. 1091

    Effect of Gender Equality on Economic Development of Household Heads in Uganda: A Case Study of Rwamucucu Sub-County, Rukiga District. by Nsimire, Millicent

    Published 2024
    “…There was critical review of the issues that have explored and studied both theoretically and empirically in the existing literature on of gender equality as an independent variable economic development as the dependent variable and the methods of data collection were put into action. The research used 80 respondents as the sample size, both qualitative and quantitative methods of data collection and analysis were employed. …”
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    Thesis
  12. 1092

    Atiyah and Adams' sale of goods / by Twigg-Flesner, Christian, 1975-, Canavan, Rick, Atiyah, P. S., Adams, John, 1939-

    Published 2021
    Table of Contents: “…Sources of the law of sale of goods -- The contract of sale -- Subject-matter of the contract -- The types of obligation created -- The existence of the goods and the duty to pass a good title -- The duty to deliver the goods -- The duty to supply the goods at the right time -- The duty to supply goods in the right quantity -- The duty to supply goods od the right quality -- Exclusion of seller's liability -- The duties of the buyer -- The transfer of property -- Risk and frustration -- Transfer of title by a non-owner -- Export sales -- International Convention on Sales of Goods ("CISG") -- Real remedies -- Personal remedies -- Rejection of the goods, rescission, and specific performance -- Action for damages -- Consumer sales contracts -- Product liability -- Manufacturers' guarantees.…”
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    Book
  13. 1093

    Çin Siyasi Düşüncesi ve Siyasi Tarihi Bağlamında Çinli Siyasi Elitler by Tuğrul Keskin

    Published 2024-12-01
    “… The book Chinese Political Elites in the Context of Chinese Political Thought and Political History by Can Ulusoy offers an in-depth examination of China's political elites, focusing on the historical and intellectual frameworks that shaped their actions and ideologies from 1840 to 1978. By drawing comparisons to similar processes in Turkish political history, Ulusoy seeks to understand China's modern political developments. …”
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    Article
  14. 1094
  15. 1095

    Repeated positron emission tomography tracing neutrophil elastase in a porcine intensive-care sepsis model by Frida Wilske, Olof Eriksson, Rose-Marie Amini, Sergio Estrada, Helena Janols, Amina Khalil, Anders Larsson, Miklós Lipcsey, Sara Mangsbo, Jonathan Sigfridsson, Jan Sjölin, Paul Skorup, Anders Wall, Viola Wilson, Markus Castegren, Gunnar Antoni

    Published 2025-02-01
    “…Abstract Background Neutrophil granulocytes are important parts of the defence against bacterial infections. Their action is a two-edged sword, the mediators killing the intruding bacteria are at the same time causing tissue damage. …”
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    Article
  16. 1096

    Penerapan Agent-Based Simulation dalam Memprediksi Penggunaan Berkelanjutan Sistem ERP by Afrin Fauzya Rizana, Fadillah Ramadhan

    Published 2020-02-01
    “…On the other side, special treatment must be performed when the majority of the ERP users have low IM and ACP. Further action that can be taken by manager with low IM and ACP on ERP users was discussed in this paper.  …”
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    Article
  17. 1097

    Association of baseline and trajectory of triglyceride-glucose index with the incidence of cardiovascular autonomic neuropathy in type 2 diabetes mellitus by Qiong Huang, Wenbin Nan, Baimei He, Zhenhua Xing, Zhenyu Peng

    Published 2025-02-01
    “…Methods Based on the Action to Control Cardiovascular Risk in Diabetes (ACCORD) trial, multivariate logistic regression models and restricted cubic splines (RCS) were deployed for elucidating the relation between baseline TyG index and the incidence of CAN. …”
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    Article
  18. 1098

    Disruption of zinc homeostasis reverses tigecycline resistance in Klebsiella pneumoniae by Jinyu Wang, Jinyu Wang, Cuiping Xia, Cuiping Xia, Zhaoxin Xia, Zhaoxin Xia, Jilu Shen, Jilu Shen

    Published 2025-02-01
    “…The changes in intracellular zinc ion levels, superoxide dismutase activity, reactive oxygen species concentration, and cell wall synthesis pathway were monitored to evaluate the mechanism of action of PBT2.ResultsOur results revealed that PBT2 successfully reversed the resistance of K. pneumoniae to tigecycline. …”
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    Article
  19. 1099

    Application of the DEB-TKTD model with multi-omics data: Prediction of life history traits of Chinese mitten crab (Eriocheir sinensis) under different salinities by Hanzun Zhang, Shipeng Dong, Hongwei Shan, Chao Yang, Fang Wang

    Published 2025-01-01
    “…The omics data were used to ascertain the physiological mode of action (pMoA) affected by salinity in the crabs. A dynamic energy budget toxicokinetic-toxicodynamic (DEB-TKTD) model was built based on these pMoAs to predict the life history traits of crabs across different salinities, including survival, growth, and reproduction. …”
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    Article
  20. 1100

    Characteristics of Land Use Change and Evaluation of Ecological Sensitivity in Chongqing by XIE Xianjian, GOU Qiantao, WU Han

    Published 2024-12-01
    “…Regions with significant changes in sensitivity levels were located in the central urban area and the southeastern Wuling Mountainous area of Chongqing. (3) The temporal and spatial evolution of comprehensive ecological sensitivity in the study area was the result of the joint action of natural environmental factors and social economic factors. …”
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    Article