Network pharmacology and molecular analysis of mechanisms underlying the therapeutic effects of Rhubarb in treating atherosclerosis and abdominal aortic aneurysm by Huilin Xu, Jun Huang, Youjie Zeng, Xia Wang, Huilin Lian, Siyi Zhang, Ren Guo

“…Five core pharmacological targets were also identified: TNF, IL-1β MMP9, TP53, and PPARG. …”
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Detection of the Extended γ-Ray Emission around TeV Source 1LHAASO J0249+6022 with Fermi-LAT by Yunlu Gong, Liancheng Zhou, Qi Xia, Shan Chang, Jun Fang, Li Zhang

“…The results show that its γ -ray spectrum can be well fitted by a single power law with an index of 1.54 ± 0.17, and integral photon flux is (4.28 ± 1.03)  × 10 ^−11 photons cm ^−2 s ^−1 . We also considered theoretically whether the nonthermal emission could originate from a pulsar wind nebula (PWN) scenario. …”
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Health-related Quality of Life and hospital costs of Finnish melanoma patients participating in the second Multicenter Selective Lymphadenectomy Trial (MSLT-II) by Pia J. Heino, Jukka Pappinen, John F. Thompson, Micaela Hernberg, Tiina A. Jahkola, Mark B. Faries

“…Tertiary care costs between the groups were also compared. Results: At 60 months, the mean HRQoL score for the CLND and observation groups for General Health were 77.3 versus 65.0 (p = 0.007, adjusted p = 0.065), for role limitations due to physical health 89.5 versus 72.3 (p = 0.029, adjusted p = 0.203) and for role limitations due to emotional problems 91.4 versus 71.9 (p = 0.006, adjusted p = 0.065) and at 48 months, 92.8 versus 71.3 (p = 0.002, adjusted p = 0.056). …”
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Sarcopenia in IBD patients and the role of nutritional and physical activity interventions in its management – a systematic review by Michalina Jurkiewicz, Karolina Siembab, Julia Białeta, Katarzyna Rowińska, Agnieszka Napieralska, Wiktor Garbarczyk, Albert Kapla, Alicja Černohorská, Daria Bednarczyk, Wiktoria Pysiewicz

“…This kind of exercises was proven to improve muscle mass, strength and physical performance. Aerobic activity is also important as it enhances metabolic capacity of the muscles. …”
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Epidemiological Changes in Hospitalized Bronchiolitis in Children Under 2 Years of Age in Hangzhou Before and After COVID-19 Restriction Easing by Xu X, Chen X, He J, Su L, Tong X, Sun Y, Huang S, Bai G, Chen Z

“…This study aimed to analyze the changes in the viral etiology of bronchiolitis in Hangzhou during the COVID-19 restriction period (2022) compared to the period following the easing of restrictions(2023).Methods: This study collected data on patients under 2 years of age who were admitted for bronchiolitis to the Department of Pulmonology at the Children’s Hospital, Zhejiang University School of Medicine (Hangzhou) from January, 1, 2022, to December 31, 2023. It also investigated seasonal variations in the incidence of bronchiolitis and pathogen distribution across different years.Results: This study included a total of 697 children with bronchiolitis, with a median age of 7.5 (4.2– 12.0) months. …”
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Abnormal sagittal patellar tilt during active knee flexion and extension on 4DCT might be associated with patellofemoral pain by Yurou Chen, Xin Liu, Bo Sheng, Mao Yuan, Furong Lv, Fajin Lv, Fan Yu, Jia Li

“…PU-QTA, P-LTPA, and PA-LTPA also decreased as the knee flexion angle increased, but P-SHLA and PA-SHLA increased. …”
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Analisis Kesiapan Kerja Mahasiwa di Era Revolusi Industri 4.0 Menggunakan Soft - System Methodology by Anthony Anthony, Eko Sediyono, Ade Iriani

“…In order to support this research, the researcher also applies Industrial Revolution 4.0 literacy which can be used by the students to make them better prepared to face the workforce of Industrial Revolution 4.0. …”
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TECHNOLOGY LITERACY AMONG PRIMARY SCHOOL TEACHERS FOR ENHANCING NUMERACY AND LITERACY SKILLS OF EARLY-GRADE PUPILS WITH HEARING IMPAIRMENTS IN TANZANIA by Hamadi Mtani, Shubi Kaijage, Neema Mduma

“…The results found that female teachers had higher technological literacy than male teachers. Also, teachers with lower education levels were found to have higher technological literacy than those with higher levels of education. …”
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Emission Characteristics of Volatile Organic Compounds from Typical Coal Utilization Sources: A Case Study in Shanxi of Northern China by Yang Xu, Hualong Yu, Yulong Yan, Lin Peng, Rumei Li, Cheng Wang, Zhiyong Li

“…As a major source of volatile organic compounds (VOCs), coal utilization also led to high national emissions of these pollutants. …”
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Near Junction Integration of Vapor Chamber for Transient Thermal Performance Improvements of SiC Power Module by Wei Mu, Laili Wang, Haoyuan Jin, Borong Hu, Binyu Wang, Jinfeng Zhang, Liang Wang, Teng Long

“…A novel fabrication process enables the near junction integration of VC which not only acts as heat spreaders but also conducts the drain current of MOSFETs. The thermal impedance analysis in the frequency domain highlights VC's strong attenuation effect on medium frequency thermal cycles, which are particularly damaging to power modules. …”
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Exploring BCL2 regulation and upstream signaling transduction in venetoclax resistance in multiple myeloma: potential avenues for therapeutic intervention by Rodrigo Fonseca, Yuan Xiao Zhu, Laura A. Bruins, Joseph Ahmann, Cecilia de Bonolo Campos, Esteban Braggio, Xianfeng Chen, Mariano Arribas, Susie Darvish, Seth Welsh, Erin Meermeier, Kiran K. Mangalaparthi, Richard K. Kandasamy, Greg Ahmann, J. Erin Wiedmeier-Nutor, Akhilesh Pandey, Marta Chesi, P. Leif Bergsagel, Rafael Fonseca

“…Lastly, the inhibition of AURKA and mitochondrial respiration also improved VTX sensitivity in some resistant HMCLs. …”
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Digitala läspraktiker i förskolan by Malin Nilsen

“…At the same time, they may also lead to reduced social interaction and fewer discussions about the content of the books, especially if carried out without the involvement of a participating educator. …”
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CHALLENGES FOR UNIVERSITIES TO ONLINE TECHNOLOGIES IMPLEMENTATION IN THE CONDITIONS OF WAR IN UKRAINE by Yuliia Sytnykova, Tаtyana Petrenko, Oksana Bezkorovaina, Anastasiia Ptushka

“…The psychological state of both teachers and students in the circumstances of online education was also examined. The most common psychological difficulties with online learning were connected with external ones as constant shelling, and air alarms as with internal ones as stress, anxiety, worries, depression, burnout, sadness, and frustration. …”
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Preliminary exploration of mRNA, lncRNA, and miRNA expressions in the bovine jejunum unveils novel aspects of Mycobacterium avium subspecies paratuberculosis infections by Yahui Gao, Jie Cao, Bo Han, Dongxiao Sun

“…Our results demonstrated that not only mRNAs but also lncRNAs and miRNAs played important roles in regulating MAP infection in dairy cattle. …”
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El estrés calórico afecta a las hembras ovinas Blackbelly durante el verano en el trópico by Ethel Caterina García y González, Blanca Celia Pineda-Burgos, Maricela Ruiz-Ortega, Cesar Cortez-Romero, Marisol Paredes-Alvarado, José Luis Ponce-Covarrubias

“…Finalmente, la variable potencial de hidrogeno (pH) presentó variaciones, siendo más alto en los muestreos tres y seis, y los valores más bajos en los muestreos cuatro, cinco, siete y doce (p<0.001). …”
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The Impact of Stock Liquidity on Returns under Asymmetric Information and Financial Constraints by Mehrzad Alijani, Fatemeh Nezhad Hossseinian

“…This study sought to examine the relationship between stock liquidity and investment efficiency of companies listed on the Tehran Stock Exchange. It also tried to investigate whether the effect of stock liquidity on the reduction of investment in companies with information asymmetry and financial constraints is more significant or not. …”
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Safe-and-sustainable-by-design redox active molecules for energy storage applications by Clemens Wolf, Janine Maier, Julia Wenger, Georg Rudelstorfer, Christian Leypold, Julia Voglhuber-Höller, Matiss Reinfelds, Andrea Weiner, Arantza Muriana, Susanne Lux, Claudia Mair-Bauernfeind, Andreas Falk, Stefan Spirk

“…The proposed solvent change resulted in a greener alternative [changed from tetrahydrofuran (THF) to 2-methyl-tetrahydrofuran (MTHF)], and the ecotoxicity testing revealed MGQ and MHQS to be improved options. However, we also faced severe challenges regarding access to reliable LCA data on the raw material sourcing. …”
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Proximity extension assay revealed novel inflammatory biomarkers for follicular development and ovarian function: a prospective controlled study combining serum and follicular flui... by Chong Wang, Ying Feng, Yu Chen, Xianhua Lin, Xiangjuan Li

“…Because systemic inflammation has also been found to contribute to diminished ovarian reserve (DOR) in previous studies, do certain serum/FF inflammatory biomarkers affect both follicular development and ovarian function?…”
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MAEMC-NET: a hybrid self-supervised learning method for predicting the malignancy of solitary pulmonary nodules from CT images by Tianhu Zhao, Tianhu Zhao, Yong Yue, Hang Sun, Jingxu Li, Yanhua Wen, Yudong Yao, Wei Qian, Yubao Guan, Shouliang Qi, Shouliang Qi

“…These results not only significantly surpass the joint diagnosis by two experienced chest radiologists (77.3% accuracy) but also outperform the current state-of-the-art methods. …”
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Measuring Chinese negative emotion towards climate change: Psychometric properties of the Chinese version of Climate Change Anxiety Scale by Sam SS Lau, Kubi Appiah, Cherry CY Ho, Marco CH Cheng, Bo-Yi Yang

“…Introduction: In response to growing concerns over negative emotions towards climate change worldwide, it is essential that a validated and reliable scale is available for the generalizability of the constructs being measured, and it is not just applicable to Western context, but also the East. Method: The present study aims to conduct a psychometric investigation of the 13-item Climate Change Anxiety Scale (CCAS) of Clayton and Karazsia in Traditional Chinese using a large sample (N = 1,567) of Chinese individuals in Hong Kong, China. …”
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