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6421
Top health service concerns: a data mining study of the Shanghai health hotline
Published 2025-02-01“…The top 10 health service concerns identified in Shanghai included medical staff attitudes, medications, fees, registration, family planning, medical disputes, ambulance services, environmental health, illegal medical practices, and immunization.ConclusionsThis study not only identifies critical issues within the Shanghai health service system but also offers actionable insights to inform targeted policy interventions. …”
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6422
Development of Stylistics and Rhetoric in Lithuania
Published 2024-03-01“…The most extensive and comprehensive “Lietuvių kalbos stilistika” [Stylistics of the Lithuanian Language] by Juozas Pikčilingis was also prepared at that time. After the restoration of independence, rhetoric thrived. …”
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6423
Molecular characterization of putative antibiotic resistance determinant and virulence factors genes of Acinetobacter baumannii strains isolated from intensive care unit patients i...
Published 2025-04-01“…Method: The A. baumannii isolates were confirmed by the VITEK-2 automated system and 16S rRNA phylogenetic relatedness. …”
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6424
MECHANISMS FOR ENSURING THE ECONOMIC DEVELOPMENT OF RURAL AREAS THROUGH THE FORMATION OF THEIR ENERGY DEPENDENCE BASED ON THE INTENSIFICATION OF BIOFUEL PRODUCTION
Published 2024-12-01“…This comprehensive approach enabled an in-depth analysis of the opportunities and limitations of bioenergy in Ukraine, in particular by comparing biomass use practices in developed countries and identifying effective strategies for the Ukrainian context. The article also discusses the prospects for improving the regulatory framework to create favourable conditions for bioenergy development, the need for infrastructure improvements and the involvement of local communities in renewable energy projects. …”
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6425
Divergent thinking in groups during cold-water immersion is impaired by cold stress not the cold shock response
Published 2025-02-01“…To date, research shows that executive functioning is generally impaired by intense, acute stress, which implies the ability to think through potential actions to maximize survival would also be impaired by the cold shock response.MethodsTo examine whether the severity of cold shock response impairs higher-level thinking in a group, 29 active duty service members completed a group format Divergent Association Task (DAT; 4–5 per group) prior to and during a 13-min cold-water immersion (water temperature: 1.3°C, air temperature: −2.7°C).ResultsResults showed no relationship between cold shock response magnitude, indexed by peak heart rate, and DAT performance. …”
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6426
Heterochrony in orthodenticle expression is associated with ommatidial size variation between Drosophila species
Published 2025-02-01“…When otd expression is driven prematurely during D. melanogaster eye development, the ommatidia grow larger, supporting a possible role for the timing of otd expression in regulating ommatidial size. We also identified potential direct targets of Otd that are differentially expressed between D. mauritiana and D. simulans during ommatidial maturation. …”
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6427
Effects of dietary chlorogenic acid supplementation on laying performance, egg quality, antioxidant capacity, and liver lipid metabolism in late-peak laying hens
Published 2025-12-01“…Significant improvements were also noted in the Haugh unit, albumen height, and yolk colour in both CGA groups, along with elevated levels of ovomucin in the albumen and lutein in the yolk. …”
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6428
Microbiota governs host chenodeoxycholic acid glucuronidation to ameliorate bile acid disorder induced diarrhea
Published 2025-02-01“…In vitro, important gene involved in the reduction of BA disorder induced-diarrhea were screened by RNA transcriptomics sequencing, and activation pathway of FXR-SIRT1-LKB1 to alleviate BA disorder diarrhea and P53-mediated apoptosis were proposed in vitro by multifarious siRNA interference, CO-IP, immunofluorescence, and so on, which mechanism was also verified in a variety of mouse models. Results Here, we reveal for the first time that core microbiota derived I3C represses gut epithelium glucuronidation, particularly 3β-glucuronic CDCA production, which reaction is mediated by host UDP glucuronosyltransferase family 1 member A4 (UGT1A4) and necessary of BA disorder induced diarrhea. …”
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6429
Platycodin D inhibits tumor proliferation by modulating macrophage polarization through promoting JAK2 ubiquitination
Published 2025-02-01“…Treatment with PD led to a significant reduction in melanoma tumor weight, inhibition of the mTOR pathway, and suppression of M2-polarized macrophages. PD also downregulated M2 macrophage markers, impaired mitochondrial function, reduced ROS production, and diminished the tumor-promoting functions of TAMs. …”
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6430
Profile of Egyptian pediatrics with COVID-19: insights from healthcare providers in Egypt
Published 2025-02-01“…While initially thought to affect adults predominantly, it became clear that children and adolescents were also susceptible to the virus's effects. This study aims to explore the epidemiological patterns, clinical features, laboratory and radiological characteristics, and outcomes of COVID-19 infection in a group of Egyptian children (≤ 18 years). …”
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6431
STING agonist-based treatment promotes vascular normalization and tertiary lymphoid structure formation in the therapeutic melanoma microenvironment
Published 2021-02-01“…Consistent with a central role for DC in TLS formation, ADU S-100-activated mCD11c+ DCs also exhibited upregulated expression of TLS promoting factors including lymphotoxin-α (LTA), interleukin (IL)-36, inflammatory chemokines and type I interferons in vitro and in vivo. …”
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6432
Advances in Radiation Protection in Oral and Dental Radiology: Pragmatic Approaches and Recent Innovations
Published 2025-01-01“…The primary conclusions and relevant units of measurement are also included. According to the predefined inclusion and exclusion criteria, a total of 26 articles were systematically reviewed for this study. …”
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6433
Immunodeficiency, Centromeric Instability, and Facial Dysmorphism (ICF) Syndrome: How HSCT alters the impairment of the DNA methylation process
Published 2025-02-01“…Advances in molecular biology and genetics enabled insights into the DNA methylation machinery, which allowed us to gain a more precise understanding of the pathogenesis of ICF and also opened up opportunities for the development of new therapeutic options. …”
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6434
The study of miRNA-211 affects melanogenesis progress in Cashmere goats via suppressing <i>AP1S2</i>
Published 2025-02-01“…Following subcutaneous injection of antagomiRNA-211 (chemical modification inhibitor), the expression levels of the <i>AP1S2</i> gene and protein were enhanced, and the localization in the hair follicle was also increased. Furthermore, reduction in melanin content in the skin was detected. …”
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6435
Borogon: Ethnonym and Ethnic History
Published 2024-11-01“…Those sources, however, provide only fragmentary information about the bearers of Borogon identity. It is also proposed the etymology, supported by linguistic data presented in different lexical and etymological dictionaries and recent results of researches on the development of historical phonetics of the Mongolic and Turkic languages. …”
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6436
Effects of coenzyme q10 supplementation on metabolic and reproductive outcomes in obese rats
Published 2025-02-01“…Moreover, it caused a reduction in the number of AMH + follicles (p < 0.001), increasing follicular atresia (p < 0.05) and serum estradiol levels (p < 0.05). Obesity also altered the estrous cycle and reduced the ovulation rate (p < 0.05). …”
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6437
E-HEART score: A novel scoring system for undifferentiated chest pain in the emergency department
Published 2023-10-01“…The E-HEART Score was also compared with existing traditional scoring systems for risk-stratifying acute chest pain. …”
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6438
Trend analysis of precipitation and temperature in Lahaul-Spiti district, Himachal Pradesh, India
Published 2025-02-01“…Hence, it is essential to study the trends of temperature and precipitation for the region and also its effects on sustainable development. The objective of this study is to investigate the variability of rainfall and temperature on a monthly, seasonal, and annual basis from 1981 to 2021. …”
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6439
Understanding Citizens’ Response to Social Activities on Twitter in US Metropolises During the COVID-19 Recovery Phase Using a Fine-Tuned Large Language Model: Application of AI
Published 2025-02-01“…ConclusionsThe results show a gradual decline in sentiment and interest in restrictions across all 3 cities as the pandemic approached its conclusion. These results are also ensured by a sentiment estimation model fine-tuned on actual Twitter posts. …”
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6440
Arab representation in Israeli healthcare professions: achievements, challenges and opportunities
Published 2025-02-01“…In medicine, dentistry, and pharmacy, many of the licensed Arab health professionals had studied outside of Israel; this phenomenon also exists for nursing but is less widespread there. …”
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