Anti-VEGF therapy improves EGFR-vIII-CAR-T cell delivery and efficacy in syngeneic glioblastoma models in mice by Dai Fukumura, Rakesh K Jain, Jun Ren, Xinyue Dong, Zohreh Amoozgar, Somin Lee, Meenal Datta, Sylvie Roberge, Mark Duquette

“…We found that treatment with the anti-mouse VEGF antibody (B20) improved CAR-T cell infiltration and distribution throughout the GBM TME, delayed tumor growth, and prolonged survival of GBM-bearing mice compared with EGFRvIII-CAR-T cell therapy alone. Our findings provide compelling data and a rationale for clinical evaluation of anti-VEGF agents with CAR T cells for GBM patients.…”
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Combined effects of co-exposure to microcystin-LR and polystyrene microplastics on growth, brain pathology and thyroid hormone homeostasis in adult zebrafish by Wang Lin, Ling Liao, Ling Ling, Huimin Luo, Ying Jiang, Xinru Li, Yilong Yao, Pinhong Yang

“…In our study, male zebrafish (Danio rerio) were exposed to environmentally relevant concentrations of MCLR alone (0, 0.8, 4, 20 μg/L) and a mix of MCLR and PSMPs (100 μg/L) for 60 days. …”
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Differentiating the Acceleration Mechanisms in the Slow and Alfvénic Slow Solar Wind by Yeimy J. Rivera, Samuel T. Badman, J. L. Verniero, Tania Varesano, Michael L. Stevens, Julia E. Stawarz, Katharine K. Reeves, Jim M. Raines, John C. Raymond, Christopher J. Owen, Stefano A. Livi, Susan T. Lepri, Enrico Landi, Jasper. S. Halekas, Tamar Ervin, Ryan M. Dewey, Rossana De Marco, Raffaella D’Amicis, Jean-Baptiste Dakeyo, Stuart D. Bale, B. L. Alterman

“…Recent work suggests that fast solar wind requires additional momentum beyond what can be provided by the observed thermal pressure gradients alone, whereas it is sufficient for the slowest wind. …”
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Effects of exogenous sugar on color phenotype and anthocyanin synthesis in the spathe of Zantedeschia hybrida by LÜ Chengcong, ZHANG Le, ZHAO Meng, ZHANG Zijun, HUANG Shasha, JIN Xuehua

“…Expression of ZhMYB, ZhCHS, and ZhCHI under GHG treatment was lower than glucose alone. [Conclusion] Appropriate amount of exogenous glucose, mannose, and mannitol can effectively promote anthocyanin accumulation in the spathe of Z. hybrida and improve color appearance. …”
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A rugalmasítás határán: bérmunkaviszonyok a kertészeti ágazatban by András Vigvári, Krisztina Németh

“…Adaptációs stratégiájuk sikere azonban nem pusztán a kertészetek gazdasági helyzetétől, tőkeellátottságától, üzemméretétől és technológiákhoz való viszonyától függ, hanem olyan strukturális folyamatok is befolyásolják, mint a birtokkoncentráció vagy a foglalkoztatási viszonyok mezőgazdaságon túlmutató átrendeződése. …”
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Synergistic effect of polymer and graphene oxide nanocomposite in heterogeneous layered porous media: a pore-scale EOR Study by M. Iravani, M. Simjoo, A. H. Molaei

“…It demonstrated a significant improvement in oil recovery (as much as 10%) compared to polymer flooding alone, paving the way for further research on GOPN for EOR applications and more efficient oil production.…”
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Effect of pasak bumi (Eurycoma longifolia Jack), DHA, and seluang fish (Rasbora spp.) on neuroinflammation and neurotransmitter alterations in malnourished rats by Triawanti, Didik Dwi Sanyoto, Meitria Syahadatina Noor, Dimas Ikhsan Airlangga

“…Treatments involving pasak bumi extract, both alone and in combination with DHA or seluang fish, reduced IL-6 levels. …”
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Entre architecture, sémiotique et physique, y a-t-il place pour la force comme outil descriptif ? by Manar Hammad

“…Depuis cinquante ans, nous avons soumis l’architecture à un questionnement sémiotique qui tente d’en rendre compte. …”
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Response of some wheat cultivars to plot orientation and foliar boron levels by Lana Dhahir Mohammed, Sami Mohammad Amin Mohammed Amin

“…There were not significant differences observed among different level of boron alone and different cultivars in all studied traits except plant height and 1000 kernels weight of V2 increased compared to other cultivars. …”
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Unlocking the potential of rice straw: Sustainable utilization strategies for Bangladesh by Bidhan Nath, Md Moudud Ahmmed, Subrata Paul, Md Durrul Huda, Mohammad Afzal Hossain, Sharmin Islam

“…In the 2021–2022 season alone, Bangladesh produced 52.25 million tons of rice straw, with an energy potential of 189.52 × 109 MJ. …”
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Nighttime Blue Lighting and Downward Airflow to Manage Tipburn in Indoor Farm Lettuce by John Ertle, Chieri Kubota

“…A leaf gas exchange analysis showed that application of B100 lighting alone increased nighttime leaf conductance by more than 50% and transpiration by 25% over nighttime darkness, while the results of B80R20 treatment were not different from those of the B100 or control treatments. …”
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Investigation of the liquid-vapor equilibrium in the mixture of carbon dioxide and normal alkanes in binary systems using the Peng-Robinson equation of state modified with mixing r... by Ahad Khaghani, Mojtaba Saei Moghaddam, Mohammad Fani Kheshti

“…Results show that the Peng-Robinson model alone has average errors of 5.82 % in the vapor phase and 7.24 % in the liquid phase, emphasizing the need for binary interaction coefficients for accuracy. …”
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Diagnostic ultrasound enhances, then reduces, exogenously induced brain activity of mice by Henry Tan, Devon J. Griggs, Devon J. Griggs, Lucas Chen, Kahte Adele Culevski, Kathryn Floerchinger, Alissa Phutirat, Gabe Koh, Nels Schimek, Pierre D. Mourad, Pierre D. Mourad

“…In a separate experiment, we showed that tDUS alone, without a blinking light, had no observable effect on median brain activity, but upon its cessation, brain activity decreased. …”
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Liver cirrhosis epidemiology in Chelyabinsk region in 2006-2015 by A. I. Dolgushina, Ye. R. Olevskaya, A. N. Tarasov, M. S. Kazakova, A. Yu. Markina

“…By 2015 the decline in mortality due to alcohol-induced LC down to 12.6 cases per 100,000 population alone with increase of female proportion up to 42.5% was noted. …”
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Anterior Cruciate Ligament Allograft Reconstruction Outcome Independent of Patient’s Age by Parimal Rana, Jane Brennan, Anagh Astavans, Sneha Kuppireddy, Christina Morganti, Benjamin M Petre, Andrea Johnson, Justin J Turcotte, Daniel Redziniak

“…Discussion and Conclusions: The results of the current study demonstrate that age does not significantly impact allograft ACLR outcomes. Age alone should not be the sole determining factor when considering ACL surgery, emphasizing the importance of personalized factors in decision-making.…”
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The impact of fruit and vegetable intake on healthcare costs and preventive care in older adults: evidence from SHARE data by S. Asieh Hosseini Tabaghdehi, Cristina Elisa Orso, Cristina Tealdi, Simona Tenaglia

“…Conclusion These findings suggest that while fruit and vegetable consumption alone may not prevent hospitalizations in this segment of the population, it is linked to reduced re-hospitalization risk and shorter inpatient durations when hospitalized. …”
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Effects of different fertilization treatments on ground-dwelling arthropods and their functional groups in agricultural landscapes by Ziqi Bian, Ziqi Bian, Lyuyi Liu, Lyuyi Liu, Yan Li, Yan Li, Yanli Li, Yanli Li, Shengyan Ding, Shengyan Ding

“…Conversely, organic matter became the primary determinant when organic fertilizers were used alone. Interestingly, when chemical and organic fertilizers were combined, soil total nitrogen, pH, and available phosphorus were identified as the principal drivers. …”
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Prevalence and sociodemographic characteristics of functional impairment in community-dwelling older adults in China: a cross-sectional study by Yun Li, Li Zhang, Zhe Tang, Lina Ma, Pan Liu, Xiaxia Li, Wenhua Yu, Yaxin Zhang

“…Illiteracy, no spouse, living alone, poor self-reported health, low income, limited meat intake, less exercise, chronic diseases and geriatric syndromes were associated with functional impairment. …”
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Examination of Depression Levels in Individuals Aged 65 and Over by Rukuye Aylaz, Nuri Yıldırım, Fidan Balkaya

“…In the study, it was found that the mean depression scores of the participants who were illiterate, living alone, living on 65-year-old pension and having more than one chronic disease were higher. …”
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Du concept de vulnérabilité à la perception des dépérissements forestiers par la société by Nathalie Bréda

“…Les cadres conceptuels dans lesquels les scientifiques travaillent pour comprendre l’origine des dépérissements, mieux les gérer et réduire leur occurrence ont évolué avec les progrès réalisés et les enjeux rencontrés. Nous avons eu l’opportunité d’interroger des citoyens sur leur perception de la santé des forêts, leur compréhension des processus en cours et de débattre de solutions pour aider la forêt à aller mieux. …”
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