Occupational adjustments and work ability of young adult cancer survivors: results from the AYA-Leipzig study by Hannah Brock, Katharina Schröter, Michael Friedrich, Annekathrin Sender, Diana Richter, Anja Mehnert-Theuerkauf, Kristina Geue, Katja Leuteritz

“…Conclusion Our results highlight the need for targeted occupational counselling throughout the treatment and even beyond the return-to-work process, considering individual and social factors.…”
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In vitro study on the inhibitory effect of various essential oils against murine coronavirus mouse hepatitis virus A-59 replication by Karelle Contant, Shiv Shankar, Monique Lacroix

“…Tanacetum annuum at 10000 µg/ml inhibited 5.03-log MHV-A59. Beyond 4-log, the drug can be qualified as an antiviral according to the guidelines of ICH. …”
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Descripción de la estructura familiar de una muestra de pacientes con hemofilia. Comparación Argentina-México / Description of a Sample of Hemophilia Patients’ Family Structures: A... by Maricela Osorio-Guzmán, Silvina Graña

“…Abstract: Chronic diseases such as hemophilia go beyond the containment of institutional health care systems and involve not only a patient’s personal daily life but also their social networks. …”
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REGIONAL FACTORS OF MECHANISMS TRANSFORMATION FOR STRENGTHENING THE ECONOMIC SECURITY OF ENTREPRENEURIAL ACTIVITY IN THE INDUSTRIAL SECTOR OF UKRAINE by Tetyana Calinescu, Olena Zelenko, Serhii Pidmohylnyi

“…This support should extend beyond professional reorientation, encompassing social and everyday support to ensure the proper quality of life for these individuals.…”
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The Impact of Atorvastatin on Intraprostatic Biomarkers – Prognostic Value of 3LS-score – Follow-up of ESTO1-Trial by Eemil Lehtonen, Maiju Vertanen, Heimo Syvälä, Teemu Tolonen, Seppo Auriola, Teuvo Tammela, Aino Siltari, Teemu Murtola

“…Background: Prostate cancer (PCa) remains a global health burden, with limited reliable biomarkers beyond prostate-specific antigen (PSA). Statins have been associated with survival benefits in advanced Pca, potentially by modulating cholesterol metabolism and tumor biology. …”
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Age-stratified analysis of the BMI-kidney stone relationship: findings from a national cross-sectional study by Liuliu Zhou, Wei Gu, Yufeng Jiang, Haimin Zhang

“…In the 40–59-year group, the risk of kidney stones peaked and then plateaued as BMI increased beyond a certain threshold. In the ≥60-year age group, risk initially increased with BMI but then slightly declined. …”
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Scaling of fractured rock flow. Proposition of indicators for selection of DFN based flow models by Davy, Philippe, Le Goc, Romain, Darcel, Caroline, Selroos, Jan-Olof

“…A 4th indicator on the representative elemental volume could in principle be defined but the data show that this volume/scale is beyond the 300 m investigated. We tested a series of numerical models built in three steps: the geo-DFN based on the observed fracture network, the open-DFN which is the part of the geo-DFN where fractures are open, and a transmissivity model applying on each fracture of the open-DFN (Discrete Fracture Network). …”
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Health IT Implementation and the Impact of the COVID-19 Pandemic on Clinician-IT Dynamics: Qualitative Study by Adeola Bamgboje-Ayodele, Adrian Boscolo, Mitchell Burger, Owen Hutchings, Miranda Shaw, Tim Shaw, Amina Tariq, Sundresan Naicker, Steven McPhail, Melissa Baysari

“…While health care organizations are keen to transition beyond the ways of working during the pandemic, it is imperative to learn from the health IT implementation successes and failures that occurred in the pandemic via process evaluations. …”
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European Working Time Directive and doctors’ health: a systematic review of the available epidemiological evidence by Consol Serra, Evangelia Demou, Ewan B Macdonald, Sergio Vargas-Prada, Maria Cruz Rodriguez-Jareño, Kaveh A Sanati, Alenka Škerjanc, Pedro G Reis, Ritva Helimäki-Aro

“…Objective To summarise the available scientific evidence on the health effects of exposure to working beyond the limit number of hours established by the European Working Time Directive (EWTD) on physicians.Design A systematic literature search was conducted in PubMed and EMBASE. …”
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Severe COVID-19 disease is associated with genetic factors affecting plasma ACE2 receptor and CRP concentrations by Verena Vogi, David Haschka, Lukas Forer, Simon Schwendinger, Verena Petzer, Stefan Coassin, Ivan Tancevski, Thomas Sonnweber, Judith Löffler-Ragg, Elisabeth Puchhammer-Stöckl, Marianne Graninger, Dominik Wolf, Florian Kronenberg, Johannes Zschocke, Emina Jukic, Günter Weiss

“…The innovative approach of polygenic scores to investigate genetic factors in COVID-19 severity should provide a comprehensive approach beyond single-gene studies. In our cohort of 156 patients of European ancestry, two overlapping Polygenic Scores (PGS) predicting a genetic predisposition to basal CRP concentrations were significantly different between non-severe and severe COVID-19 cases and were associated with less severe COVID-19 outcomes. …”
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Ivermectin as a promising therapeutic option for onchocerciasis‐associated epilepsy by Mohammad Amin Manavi, Razieh Mohammad Jafari, Hamed Shafaroodi, Mohammad Sharifzadeh, Ahmad Reza Dehpour

“…Clinical research in the Congo among infected epileptics on anti‐seizure medications (ASMs) suggested ivermectin may decrease seizure frequency following oral administration of ivermectin tablets (3 mg). Beyond its antiparasitic properties, ivermectin has demonstrated anticonvulsant effects against clonic and tonic–clonic seizures, likely through modulation of GABAA receptor and neuroinflammation. …”
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Biochemical Pattern of Methylmalonyl-CoA Epimerase Deficiency Identified in Newborn Screening: A Case Report by Evelina Maines, Roberto Franceschi, Francesca Rivieri, Giovanni Piccoli, Björn Schulte, Jessica Hoffmann, Andrea Bordugo, Giulia Rodella, Francesca Teofoli, Monica Vincenzi, Massimo Soffiati, Marta Camilot

“…Increased MMA levels may be negligible at NBS as they may reach relevant values beyond the first days of life and thus could be identified only in confirmatory analyses.…”
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Impact of rock mineralogy on reactive transport of CO2 during carbon sequestration in a saline aquifer by Mohamed Gamal Rezk, Ahmed Farid Ibrahim

“…Elevating Anorthite concentrations speeds up CO2 mineralization, ensuring secure storage in saline aquifers, with a minimum threshold concentration of 0.05 volume fraction; beyond this point, no further changes in CO2 mineralization are observed. …”
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Hydrochemical assessment of borehole water in Effurun, Delta state Niger Delta, Nigeria: implications for public health and safety by Odunayo Tope Ojo, Chiaka Joy Ike, Adegoke Ige Aladeboyeje, Olayiwola Grace Olaseeni, Olumuyiwa Femi Adewumi

“…The study highlights diverse hydrochemical characteristics of Effurun's borehole water, with some areas showing contamination beyond acceptable limits. Regular monitoring is essential to ensure safe drinking water and address potential health risks. …”
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Cohort profile: Born in Wales—a birth cohort with maternity, parental and child data linkage for life course research in Wales, UK by Amrita Bandyopadhyay, Sarah Davies, Michaela James, Sinead Brophy, Sam Dredge, Hope Jones, Mike J Seaborne, Natasha L Kennedy, Adele Battaglia

“…We present the descriptive data available in the core dataset, and the future expansion plans for the database beyond its initial development stage.Participants Descriptive information from 2011 to 2023 has been gathered from the National Community Child Health Database (NCCHD) in SAIL. …”
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Call for Papers: Intergenerational Justice Prize 2020 by FRFG, IF (Foundation for the Rights of Future Generations, Intergenerational Foundation)

“…• To what extent do inheritance (and gift) tax systems differ in terms of tax rates and allowances according to degree of kinship in OECD countries or beyond? What percentage of the population is liable to these taxes? …”
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Pattern and Predictors of Maternal Healthcare Services Utilization among Women of Reproductive Age in Lagos, Nigeria by Esther Oluwakemi Oluwole, Alero Ann Roberts, Ifeoma Peace Okafor, Victoria Oluwasola Yesufu

“…Conclusion: This study reveals high awareness and utilization of maternal health services but highlights room for improvement in early antenatal care registration and postnatal care beyond the child’s immunization.…”
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Optimizing Energy and Spectral Efficiency in Mobile Networks: A Comprehensive Energy Sustainability Framework for Network Operators by Luis Mata, Marco Sousa, Pedro Vieira, Maria Paula Queluz, Antonio Rodrigues

“…By leveraging Machine Learning (ML) and Explainable Artificial Intelligence (XAI) techniques applied to live data - including Performance Management (PM) and Energy Management (EM) metrics - integrated with domain expertise, the framework goes beyond deterministic computation to identify the root-cause factors influencing the BSs’ energy class, thereby enabling targeted optimisation. …”
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Hepatocellular carcinoma: signaling pathways and therapeutic advances by Jiaojiao Zheng, Siying Wang, Lei Xia, Zhen Sun, Kui Ming Chan, René Bernards, Wenxin Qin, Jinhong Chen, Qiang Xia, Haojie Jin

“…Several signaling pathways are dis-regulated in HCC and cause uncontrolled cell propagation, metastasis, and recurrence of HCC. Beyond the frequently altered and therapeutically targeted receptor tyrosine kinase (RTK) pathways in HCC, pathways involved in cell differentiation, telomere regulation, epigenetic modification and stress response also provide therapeutic potential. …”
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Effects of Agrochemicals on Soil Bio-Physico-Chemical Properties in Potato Production Systems in the Highlands of South Western Uganda. by Twebaze, Jeniffer

“…Lead (Pb) was recorded in the range of 0.05-113 mg kg-1 and Cd between 0.05-32 mg kg-1 with most fields having higher concentrations beyond the recommended levels of <40 mg kg-1 and <1.0, mg kg-1 respectively. …”
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