Phase II clinical trial assessing the addition of hyperthermia to salvage concurrent chemoradiotherapy for unresectable recurrent head and neck cancer in previously irradiated pati... by Kai-Lin Yang, Mau-Shin Chi, Chung-Yu Hao, Hui-Ling Ko, Yi-Ying Huang, Ren-Hong Wu, Hung-Chih Lai, Ying-Chu Lin, Sheng-Po Hao, Kwan-Hwa Chi

“…Conclusions Adding hyperthermia to salvage CCRT greatly enhances tumor response and survival rates compared to historical re-irradiation outcomes for previously irradiated unresectable recurrent head and neck cancer, with manageable toxicities. …”
Get full text

Analisis Kesiapan Penerapan Process Mining pada Sistem Manajemen Pembelajaran Universitas Telkom by Angelina Prima Kurniati, Gede Agung Ary Wisudiawan

“…Studi kelayakan ini diakhiri dengan diskusi tentang kelayakan LMS untuk dianalisis dengan process mining, evaluasi oleh tim ahli LMS, dan usulan pengembangan LMS di masa mendatang.   Abstract Computer-based Learning Management Systems (LMS) are commonly used in educational institutions, including universities. …”
Get full text

TGF-β induces cholesterol accumulation to regulate the secretion of tumor-derived extracellular vesicles by Dorival Mendes Rodrigues-Junior, Chrysoula Tsirigoti, Konstantina Psatha, Dimitris Kletsas, Michalis Aivaliotis, Carl-Henrik Heldin, Aristidis Moustakas

“…EV-associated latent-TGF-β1 activated SMAD signaling, even when EV uptake was blocked by heparin, indicating competent signaling capacity from target cell surface receptors. …”
Get full text

Sinensetin attenuates hepatic ischemia-reperfusion injury through suppressing GRP78/CHOP-mediated endoplasmic reticulum (ER) stress in mice by Yihong Yang, Guanghua Xiong, Huangqi Shi, Yulin Peng, Jinghong Liu, Yaxuan Jiang, Min Lu, Hongbo Liu, Yong Liu

“…In addition, hepatocytic necrosis and lipid deposition were significantly improved under SEN pretreatment conditions compared to the HIRI group alone. Meanwhile, HIRI can significantly increase the expression of genes related to liver injury and inflammation, while SEN pretreatment can lead to a concentration-dependent decrease in these genes. …”
Get full text

Correlates of prior HIV testing and schistosomiasis treatment: Baseline survey findings from the "creating demand for fishermen's schistosomiasis HIV services" (FISH) cluster-rando... by Geoffrey Kangogo, Donaldson F Conserve, Sekeleghe Kayuni, Moses K Kumwenda, Kathryn L Dovel, James Chirombo, Peter MacPherson, Elizabeth L Corbett, Anthony Butterworth, Augustine Talumba Choko

“…Prevalence of willingness to attend a beach clinic was computed.<h4>Results</h4>A total of 6,297 fishermen were surveyed from the 45 clusters with harmonic mean number of fishermen per cluster of 112 (95% CI: 97; 134). …”
Get full text

The Identification of FN1 as an Early Diagnostic Marker for Recurrent Abortion by Single-Exosome Profiling by Wang C, Lu Z, She G, Chen K, Zhou H, Zhan X, Yu H, Pi L, Zuo L, Che D

“…After PBA treatment, samples were analyzed for single exosomes, and exosomes from each group were compared using volcano plots, dot plots, and ROC curves.Results: By intersecting all significantly differentially expressed genes obtained from comparisons between the normal pregnancy control group and the recurrent abortion group, including the RA before abortion, RA after abortion, and RA non-pregnancy groups, we identified seven shared differential genes: FN1, APIPOQ, CDH13, DSG1, CLDN4, CD36, and ULBP3. …”
Get full text

Preoperative prediction of IDH genotypes and prognosis in adult-type diffuse gliomas: intratumor heterogeneity habitat analysis using dynamic contrast-enhanced MRI and diffusion-we... by Xingrui Wang, Zhenhui Xie, Xiaoqing Wang, Yang Song, Shiteng Suo, Yan Ren, Wentao Hu, Yi Zhu, Mengqiu Cao, Yan Zhou

“…Results Three habitats were identified: Habitat 1 (hypo-vasopermeability and hyper-cellularity), Habitat 2 (hypo-vasopermeability and hypo-cellularity), and Habitat 3 (hyper-vasopermeability). Compared to the IDH wild-type group, the IDH mutant group exhibited lower mean Ktrans values in Habitats 1 and 2 (both P < 0.001), higher volume (P < 0.05) and volume percentage (pVol, P < 0.01) of Habitat 2, and lower volume and pVol of Habitat 3 (both P < 0.001). …”
Get full text

Keamanan Data Menggunakan Secure Hashing Algorithm (SHA)-256 dan Rivest Shamir Adleman (RSA) pada Digital Signature by Juniar Hutagalung, Puji Sari Ramadhan, Sarah Juliana Sihombing

“…The decryption result is comparable to the e-document hash, so the verified document is considered valid. …”
Get full text

Rat Model of Cystic Neutrophilic Granulomatous Mastitis by Corynebacterium Kroppenstedtii by Wang M, Zeng Y, Liu M, Zhang D, Zhao D, Wang J, Liu Y, Zhao W

“…Histopathology revealed minimal inflammatory cell infiltration and no granulomatous formation in groups B and C. Group F showed no masses or inflammatory cell infiltration. …”
Get full text

Klasifikasi Kelas Kata (Part-Of-Speech Tagging) untuk Bahasa Madura Menggunakan Algoritme Viterbi by Ilham Firmansyah, Putra Pandu Adikara, Sigit Adinugroho

“…There is a specific field in computer science that processes natural language, which is called Natural Language Processing. …”
Get full text

Exploring the benefits and prescribing informations of combining East Asian herbal medicine with conventional medicine in the treatment of rheumatoid arthritis: A systematic review... by Hee-Geun Jo, Jihye Seo, Eunhye Baek, Donghun Lee

“…EACM was associated with higher ACR responses: ACR 20 (RR: 1.2332; 95 % CI: 1.1852–1.2831, p < 0.0001), ACR 50 (RR: 1.3782; 95 % CI: 1.2936–1.4684, p < 0.0001), and ACR 70 (RR: 1.7084; 95 % CI: 1.5555–1.8762, p < 0.0001), as well as a favorable AEI (OR: 0.3977; 95 % CI: 0.3476–0.4551, p < 0.0001), indicating both better efficacy and safety compared to CM alone. These patterns were consistent across eight secondary outcomes measuring pain, inflammation, and disease activity in RA. …”
Get full text

PhantomAR: gamified mixed reality system for alleviating phantom limb pain in upper limb amputees—design, implementation, and clinical usability evaluation by Cosima Prahm, Korbinian Eckstein, Michael Bressler, Zhixing Wang, Xiaotong Li, Takashige Suzuki, Adrien Daigeler, Jonas Kolbenschlag, Hideaki Kuzuoka

Get full text

Novel Procedures for Evaluating Autism Online in a Culturally Diverse Population of Children: Protocol for a Mixed Methods Pathway Development Study by Venus Mirzaei, Jeanne Wolstencroft, Georgia Lockwood Estrin, Eleanor Buckley, Shermina Sayani, Panos Katakis, Reena Anand, Tessa Squire, Eleanor Short, Paige Frankson, David Skuse, Michelle Heys

“…Sensitivity and specificity will be calculated by comparing the diagnosis of autism through CHATA with usual care. …”
Get full text

Process Evaluations of Interventions for the Prevention of Type 2 Diabetes in Women With Gestational Diabetes Mellitus: Systematic Review by Iklil Iman Mohd Sa'id, Natasha Hotung, Madeleine Benton, Iliatha Papachristou Nadal, Anisah Baharom, Matthew Prina, Barakatun Nisak Mohd Yusof, Kimberley Goldsmith, Samantha Birts, Ching Siew Mooi, Angus Forbes, Khalida Ismail, Boon How Chew

“…Women with GDM have an increased risk of developing type 2 diabetes mellitus (T2DM) later in life compared to those with normoglycemic pregnancy. While diabetes prevention interventions (DPIs) have been developed to delay or prevent the onset of T2DM, few studies have provided process evaluation (PE) data to assess the mechanisms of impact, quality of implementation, or contextual factors that may influence the effectiveness of the intervention. …”
Get full text

Pengembangan Business Intelligence Dashboard untuk Monitoring Aktivitas Pariwisata (Studi Kasus: Dinas Pariwisata Provinsi Bali) by Evan Himawan Saragih, I Putu Agung Bayupati, Gusti Agung Ayu Putri

“…This study develops an information system using the BI approach in analyzing Bali tourism data and data management by replacing paper use as computer media so that data does not just disappear, but is used as a reference when making decisions. …”
Get full text

In-Season Automated Mapping of Xinjiang Cotton Based on Cumulative Spectral and Phenological Characteristics by Yongsheng Huang, Yaozhong Pan, Yu Zhu, Xiufang Zhu, Xingsheng Xia, Qiong Chen, Jufang Hu, Hongyan Che, Xuechang Zheng, Lingang Wang

“…In the absence of samples, the accuracy of the CSP method was comparable to that of support vector machine and RF-supervised classification results, which could be realized 60&#x2013;70 days before cotton harvest. …”
Get full text

Effects of biologic therapy on novel indices of lung inhomogeneity in patients with severe type-2 high asthma by Nayia Petousi, Nick P Talbot, Ian Pavord, Peter A Robbins, Nicholas M J Smith, Graham Richmond, Asma Alamoudi, Lorenzo Petralia, Haopeng Xu, Dominic Sandhu, Grant AD Ritchie

“…Introduction/Aim Lung inhomogeneity measures obtained using computed cardiopulmonography (CCP) are sensitive to small-airways disease. …”
Get full text

Pre-exposure Prophylaxis Awareness and Endorsement among Adolescents and Young Adults in Tanzania: Insights from the 2022 Demographic and Health Survey by Alpha Johnson Kapola, Rahma Musoke, Glenda Marie Manayon, Hassan Fredrick Fussi, Hafidha Mhando Bakari, Haji Mbwana Ally, Swalehe Mustafa Salim, Zuhura Mbwana Ally, Lynn Moshi, Mariam Salim Mbwana, Habib Omari Ramadhani

“…Female respondents (adjusted odds ratio [aOR] = 0.69; 95% CI 0.51–0.91) and rural residents (aOR = 0.78; 95% CI 0.61–1.00) had lower odds of PrEP awareness compared with male respondents and urban residents, respectively. …”
Get full text

Supporting primary care clinicians in caring for patients with alcohol use disorder: study protocol for Records for Alcohol Care Enhancement (RACE), a factorial four-arm randomized... by Kara M. Magane, Richard Saitz, Sarah Fielman, Marc R. LaRochelle, Christopher W. Shanahan, Christine A. Pace, Michael LaValley, Kaley Penington, Skylar Karzhevsky, Emily Hurstak

“…Discussion The study will evaluate how a targeted EHR innovation alone, compared with population health and care management enhancements alone or in combination, impact engagement in AUD treatment, a national quality of care measure. …”
Get full text

Implementasi Algoritme Evolusioner NSGA-II pada Optimasi Daya Wireless Power Transfer Multi-Penerlima by Sabriansyah Rizqika Akbar, Eko Setiawan, Agung Setiabudi

“…The obtained optimal parameter values are compared with the results of the LTSPICE simulator application to validate the power value of the receiver. …”
Get full text