Immune microenvironment spatial landscapes of tertiary lymphoid structures in gastric cancer by Yi Xie, Haoxin Peng, Yajie Hu, Keren Jia, Jiajia Yuan, Dan Liu, Yanyan Li, Xujiao Feng, Jian Li, Xiaotian Zhang, Yu Sun, Lin Shen, Yang Chen

“…ST analysis confirmed that T and B cells co-localise within TLS, enhancing immune response activation compared to cancer nests and exerting a strong anti-tumour effect. …”
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Calculated parameters for the diagnosis of Wilson disease by Nada Syazana Zulkufli, Pavai Sthaneshwar, Wah-Kheong Chan

“…This study aimed to: (a) compare the diagnostic values of non-caeruloplasmin copper (NCC), NCC percentage (NCC%), copper-caeruloplasmin ratio (CCR) and adjusted copper in WD; and (b) derive and evaluate a discriminant function in diagnosing WD. …”
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Evaluation of Nausea and Vomiting Severity in Pregnancies Conceived Through Assisted Reproduction by Ozge Senem Yucel Cicek, Merve Demir

“…Weight change during pregnancy and hospital admission due to nausea vomiting of pregnancy were also compared to assess severe nausea vomiting of pregnancy. …”
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MyD88 inhibitor TJ-M2010-5 alleviates spleen impairment and inflammation by inhibiting the PI3K/miR-136-5p/AKT3 pathway in the early infection of Trichinella spiralis by Huifang Bai, Qianqian Dang, Guoliang Chen, Lingfeng Xie, Saining Wang, Ning Jiang, Xiaoxia Wu, Shuyan Zhang, Xuelin Wang

“…MyD88 promoter methylation results showed that the methylation levels in the 5 d group were lower compared to the control group (P < 0.05). Furthermore, the methylation led to an imbalance in anti-inflammatory regulation in the infected mice. …”
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Comparison of Real-world Outcomes Between Patients Treated with Tapentadol ER or Oxycodone CR by Mike Durkin, Jacqueline Pesa, Jessica Lopatto, Rachel Halpern, Damon Van Voorhis, Stephanie Korrer

“…**Background:** The objective of this study was to compare health care utilization and costs between matched cohorts of chronic pain patients treated with the opioids tapentadol extended release (ER) or oxycodone controlled release (CR). …”
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Small molecule metabolites drive plant rhizosphere microbial community assembly patterns by Yanwei Ma, Heqi Wang, Yalong Kang, Tao Wen

“…Our findings revealed that rhizosphere metabolites accounted for more variance in microbial community composition compared to chemical properties (ANOVA, F = 1.53, p = 0.04), enzyme activities, or root traits (ANOVA, F = 1.04, p = 0.001). …”
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Enhancing cracking resistance in semi-flexible pavements using an interfacial immersion method by Xiaoyu Liu, Kuanghuai Wu, Giovanni Giacomello, Yunpeng Yue, Fengming Ren, Xu Cai, Marco Pasetto

“…To enhance the cracking resistance of SFP, an interfacial immersion method is proposed to immerse the porous asphalt mixture (PAM) specimens using a silane coupling agent (SCA) in this paper. Compared to traditional methods. this method directly improves the crack resistance of SFP by strengthening the interface. …”
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PneumoniaCheck, a novel aerosol collection device, permits capture of airborne Mycobacterium tuberculosis and characterisation of the cough aeromicrobiome in people with tuberculos... by Tinaye L. Chiyaka, Georgina R. Nyawo, Charissa C. Naidoo, Suventha Moodley, Jose C. Clemente, Stephanus T. Malherbe, Robin M. Warren, David N. Ku, Leopoldo N. Segal, Grant Theron

“…In a subset (n = 6), PMC microbiota (bag, filter) was compared to oral washes and bronchoalveolar lavage fluid (BALF). …”
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Exploring the potential cost-effectiveness and societal burden implications of screening for fracture risk in a UK general radiography setting by E. Söreskog, B. Lopez, T. Bean, P. Lewis, N. Ashley, J. Da Palma Lopes, R. Meertens, A. Ratcliffe

“…Methods The study used a health economic model that compared the health outcomes and costs of screening with IBEX BH versus usual care for men and women aged 50 and older who had a forearm radiograph for any reason. …”
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Differed brain spontaneous neural activity between limb-onset and bulbar-onset amyotrophic lateral sclerosis patients by Si-Jie Chen, Qing-Yang Li, Jiang Zhou, Qian Wu, Yu Zhang, Qian-Qian Zhang, Hao Hu, Xiao-Quan Xu, Fei-Yun Wu, Qi Niu

“…Both ALS subtypes demonstrated distinct ALFF alterations compared to HC. Differences in ReHo values were only found between ALS-B and HC. …”
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Immune dysfunction revealed by digital spatial profiling of immuno-oncology markers in progressive stages of renal cell carcinoma and in brain metastases by Wei Wei, Michael Hurwitz, Sabina Signoretti, Lucia Jilaveanu, Toni K Choueiri, David L Rimm, Adebowale Adeniran, Sandra Martínez, Harriet M Kluger, David A Schoenfeld, Myrto Moutafi, Dijana Djureinovic, Ross D Merkin, David A Braun, Fabio Parisi

“…We profiled 76 primary tumors, 27 adjacent histologically normal kidney samples, and 86 metastases, including 24 brain metastases.Results We observed lower immune checkpoint (TIM-3 and CTLA-4), cytolytic (GZMA and GZMB), and T cell activation (CD25) protein expression in metastases compared with primary tumors in two separate cohorts. …”
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Obstacles and opportunities for care collaboration through the utilisation of a preventive care process for frail older adults: a study protocol for a mixed methods study design by Åsa Larsson Ranada, Elisabet Rothenberg, Helle Wijk, Martina Karin Boström, Pia Skott, Anette Erichsen

“…The study protocol comprises the two first phases.Phase 1 (quantitative) Data from SA (2019–2021) will be analysed to compare municipalities regarding the quality of registration in the PcP. …”
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Standard reference values of the upper body posture in healthy young female adults in Germany: an observational study by Daniela Ohlendorf, Charlotte Doerry, Vanessa Fisch, Sebastian Schamberger, Gerhard Oremek, Hanns Ackermann, Johannes Schulze

“…Objective Classifications of posture deviations are only possible compared with standard values. However, standard values have been published for healthy male adults but not for female adults.Design Observational study.Setting Institute of Occupational Medicine, Social Medicine and Environmental Medicine, Goethe-University Frankfurt/Main.Participants 106healthy female volunteers (21–30 years old; 25.1±2.7 years) were included. …”
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Limited Effects of Ultra-low Oxygen Concentration during Extended Embryo Culture on In vitro Fertilisation Outcomes in Indian Women: A Retrospective Cross-sectional Study by Deven Patel, R. G. Patel, Trupti Patel, Nikunj Patel, Naroda Maheshwari

“…Outcomes such as pregnancy rate, implantation rate, abortion rate, twinning rate, and live birth rate were compared between the groups. Statistical Analysis Used: Chi square test was applied to compare the primary and secondary outcomes between different groups. …”
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Outcomes of Hospitalized COVID-19 Patients by Risk Factors: Results from a United States Hospital Claims Database by Peter J. Mallow, Kathy W. Belk, Michael Topmiller, Edmond A. Hooker

“…The presence of CDC risk factors was associated with increased ICU utilization, longer ICU LOS, and longer hospital LOS compared to those with no risk factors. Patients with hypertension (OR 0.77, 95% CI, 0.70–0.86; P < 0.001) and those administered statins were less likely to die (OR 0.54, 95% CI, 0.49–0.60; P < 0.001). …”
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The important roles of ERAP1, ERAP2 genes polymorphisms and their DNA methylation levels in pulmonary tuberculosis by Shi-Hong Su, Xue-Qian Cai, Yong-Huai Li, Ai-Hui Xu, Qian Huang, Hua Niu, Qing-Hai You, Geng-Yun Sun

“…Results Our results showed that the GG genotype, G allele frequencies of ERAP2 gene rs2549782 were significantly increased in PTB patients compared to controls, and rs2549782 polymorphism was related to the increased risk of PTB under recessive model. …”
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Identification of m6A methyltransferase-related WTAP and ZC3H13 predicts immune infiltrates in glioblastoma by Liyun Gao, Jiaxin Gao, Jiayin He, Wenyan Fan, Xiangxin Che, Xin Wang, Tao Wang, Chunhua Han

“…Our analysis revealed that cluster1 exhibited higher WTAP expression but lower ZC3H13 expression compared to cluster2. Cluster1 showed higher levels of immune infiltration and TMB compared to cluster2. …”
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Implementation of a Targeted Technologic Screening Tool to Increase Pneumococcal Vaccine Uptake in Health-System Retail Pharmacies: A Quality Improvement Initiative by Annika Skogg, Alicia Zagel, R. May O'Donnell, Ann Philbrick, Mary Nelson, Allyson Schlichte, Kassie Klasen

“…Vaccine rates and sociodemographic characteristics were compared before and after the PDSA cycle began, and reasons for patient decline were assessed. …”
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Design and assessment of lipase-CuO nanoparticle conjugates for enhanced antimicrobial efficacy against clinical pathogens by Eman M. Handak, Dina H. Amin, Mai M. Elhateir

“…Copper oxide (CuO) nanoparticles were characterized using visual indication of greenish color formation, UV-vis spectrum analysis which revealed a strong peak at 300 nm. …”
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Application of the OMERACT Grey-scale Ultrasound Scoring System for salivary glands in a single-centre cohort of patients with suspected Sjögren’s syndrome by Lene Terslev, Simon Krabbe, Viktoria Fana, Uffe M Dohn

“…More patients with pSS compared with non-pSS had score ≥2 in at least one gland (72% vs 13%; p&lt;0.001). …”
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